GenomeNet

Database: Pfam
Entry: UL45
LinkDB: UL45
Original site: UL45 
#=GF ID   UL45
#=GF AC   PF05473.13
#=GF DE   UL45 protein, carbohydrate-binding C-type lectin-like
#=GF PI   Herpes_UL45;
#=GF AU   Moxon SJ;0000-0003-4644-1816
#=GF SE   Pfam-B_17674 (release 8.0) & Pfam-B_16138 (release 10.0)
#=GF GA   27.00 27.00;
#=GF TC   27.00 27.00;
#=GF NC   26.90 26.90;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 47079205 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Family
#=GF RN   [1]
#=GF RM   11958453
#=GF RT   Mutation of the herpes simplex virus 1 KOS UL45 gene reveals
#=GF RT   dose dependent effects on central nervous system growth. 
#=GF RA   Visalli RJ, Brandt CR; 
#=GF RL   Arch Virol 2002;147:519-532.
#=GF RN   [2]
#=GF RM   11145911
#=GF RT   The equine herpesvirus 1 UL45 homolog encodes a glycosylated
#=GF RT   type II transmembrane protein and is involved in virus egress. 
#=GF RA   Oettler D, Kaaden OR, Neubauer A; 
#=GF RL   Virology 2001;279:302-312.
#=GF RN   [3]
#=GF RM   18256535
#=GF RT   HSV-1 UL45 encodes a carbohydrate binding C-type lectin protein.
#=GF RA   Wyrwicz LS, Ginalski K, Rychlewski L;
#=GF RL   Cell Cycle. 2008;7:269-271.
#=GF RN   [4]
#=GF RM   20080138
#=GF RT   Role of the UL45 protein in herpes simplex virus entry via low
#=GF RT   pH-dependent endocytosis and its relationship to the
#=GF RT   conformation and function of glycoprotein B.
#=GF RA   Dollery SJ, Lane KD, Delboy MG, Roller DG, Nicola AV;
#=GF RL   Virus Res. 2010;149:115-118.
#=GF DR   INTERPRO; IPR008646;
#=GF DR   SO; 0100021; polypeptide_conserved_region;
#=GF CC   This family consists of several UL45 proteins. The herpes
#=GF CC   simplex virus UL45 gene encodes an 18 kDa virion envelope
#=GF CC   protein whose function remains unknown. It has been suggested
#=GF CC   that the 18 kDa UL45 gene product is required for efficient
#=GF CC   growth in the central nervous system at low doses and may play
#=GF CC   an important role under the conditions of a naturally acquired
#=GF CC   infection [1]. This family also contains several Varicellovirus
#=GF CC   UL45 or gene 15 proteins. The Equine herpesvirus 1 UL45 protein
#=GF CC   represents a type II membrane glycoprotein which has been found
#=GF CC   to be non-essential for EHV-1 growth in vitro but deletion
#=GF CC   reduces the viruses' replication efficiency [2]. Studies have
#=GF CC   shown that UL45 has a C-type lectin-like fold, suggesting that
#=GF CC   it might have a carbohydrate-binding function [3,4].
#=GF SQ   93
#=GS O56871_ILTV/33-274          AC O56871.1
#=GS A0A1I8QBD3_STOCA/127-222    AC A0A1I8QBD3.1
#=GS J9QYP6_9ALPH/2-157          AC J9QYP6.1
#=GS A0A2K5KQ70_CERAT/5-123      AC A0A2K5KQ70.1
#=GS A0A261BNF9_9PELO/3-150      AC A0A261BNF9.1
#=GS Q77Q60_9ALPH/3-192          AC Q77Q60.1
#=GS A0A3Q0JHC2_DIACI/580-708    AC A0A3Q0JHC2.1
#=GS A0A194REM0_PAPMA/2411-2525  AC A0A194REM0.1
#=GS B4JY64_DROGR/157-257        AC B4JY64.1
#=GS A0A3Q0ECY1_TARSY/6-169      AC A0A3Q0ECY1.1
#=GS A0A1U7TGV5_TARSY/6-157      AC A0A1U7TGV5.1
#=GS Q14WA2_9VIRU/25-164         AC Q14WA2.1
#=GS I1V8C8_9ALPH/19-218         AC I1V8C8.1
#=GS H9J6Q7_BOMMO/2351-2463      AC H9J6Q7.1
#=GS A0A1X9T5G1_9VIRU/100-208    AC A0A1X9T5G1.1
#=GS A0A443SMF6_9ACAR/1-94       AC A0A443SMF6.1
#=GS A0A0Y0A759_9ALPH/6-170      AC A0A0Y0A759.1
#=GS A0A068EHX7_9POXV/11-145     AC A0A068EHX7.1
#=GS Q7T5D3_CHV1/7-173           AC Q7T5D3.1
#=GS A0A482X9C4_LAOST/3-115      AC A0A482X9C4.1
#=GS A0A2A4JQC2_HELVI/2534-2647  AC A0A2A4JQC2.1
#=GS A0A067R1K6_ZOONE/6-73       AC A0A067R1K6.1
#=GS A0A068EP99_9ALPH/22-216     AC A0A068EP99.1
#=GS B4I3N0_DROSE/133-233        AC B4I3N0.1
#=GS A0A3S2P127_CHISP/2535-2650  AC A0A3S2P127.1
#=GS EP153_ASFP4/12-145          AC O89335.1
#=GS A0A452RV82_URSAM/3-150      AC A0A452RV82.1
#=GS Q69365_FHV1/7-189           AC Q69365.1
#=GS A0A1I8NGE1_MUSDO/131-223    AC A0A1I8NGE1.1
#=GS A0A1S3QRB6_SALSA/7-107      AC A0A1S3QRB6.1
#=GS A0A2J7QMK8_9NEOP/5-72       AC A0A2J7QMK8.1
#=GS O39257_EHV4/19-218          AC O39257.1
#=GS B4JQJ9_DROGR/2598-2721      AC B4JQJ9.1
#=GS CONT_DROME/133-233          AC Q9VN14.2
#=GS Q14W75_9VIRU/14-199         AC Q14W75.1
#=GS A0A087T3V6_9ARAC/12-93      AC A0A087T3V6.1
#=GS O89243_9ALPH/3-191          AC O89243.1
#=GS A0A1U7SWG4_TARSY/14-158     AC A0A1U7SWG4.1
#=GS D3YPA9_HHV1/4-171           AC D3YPA9.1
#=GS A0A212EXL4_DANPL/2339-2452  AC A0A212EXL4.1
#=GS A0A2T7NRD8_POMCA/1-146      AC A0A2T7NRD8.1
#=GS A0A2K5TXM0_MACFA/20-183     AC A0A2K5TXM0.1
#=GS A0A2H2I614_CAEJA/52-146     AC A0A2H2I614.1
#=GS A0A2K6C8E0_MACNE/20-183     AC A0A2K6C8E0.1
#=GS A0A087ZZ67_APIME/13-80      AC A0A087ZZ67.1
#=GS EV45_HHV11/4-171            AC P10229.1
#=GS R7UI05_CAPTE/1-86           AC R7UI05.1
#=GS A0A340YDA9_LIPVE/2-146      AC A0A340YDA9.1
#=GS A0A2A3EGS0_APICC/14-79      AC A0A2A3EGS0.1
#=GS E2IUC5_SHV1/4-169           AC E2IUC5.1
#=GS A0A060Q0W5_9ALPH/6-169      AC A0A060Q0W5.1
#=GS A0A2K5UXV0_MACFA/6-123      AC A0A2K5UXV0.1
#=GS EV45_EHV1B/11-211           AC P28981.1
#=GS NKG2A_PANTR/12-231          AC Q95MI5.2
#=GS A0A452QIG1_URSAM/4-144      AC A0A452QIG1.1
#=GS E0VHE2_PEDHC/68-119         AC E0VHE2.1
#=GS A0A210QJ01_MIZYE/2-82       AC A0A210QJ01.1
#=GS A0A154PRQ2_DUFNO/1-84       AC A0A154PRQ2.1
#=GS Q66077_9ALPH/1-174          AC Q66077.1
#=GS A0A2K6FPM2_PROCO/3-138      AC A0A2K6FPM2.1
#=GS A0A1S3CTW1_DIACI/3-88       AC A0A1S3CTW1.1
#=GS F8TC43_9ALPH/3-191          AC F8TC43.1
#=GS A0A2A4JNJ3_HELVI/2524-2637  AC A0A2A4JNJ3.1
#=GS A0A1V0M8J2_9ALPH/22-216     AC A0A1V0M8J2.1
#=GS EV45_GAHVM/3-192            AC P22653.1
#=GS A0A077B9A2_9ALPH/8-198      AC A0A077B9A2.1
#=GS A1YZN4_9ALPH/33-223         AC A1YZN4.1
#=GS A0A210QIS8_MIZYE/1-100      AC A0A210QIS8.1
#=GS A0A3P9CYE8_9CICH/2-130      AC A0A3P9CYE8.1
#=GS E2BBG0_HARSA/4-105          AC E2BBG0.1
#=GS A0A1U7TR39_TARSY/16-125     AC A0A1U7TR39.1
#=GS A8XY68_CAEBR/7-175          AC A8XY68.2
#=GS A0A484BNT4_DRONA/162-259    AC A0A484BNT4.1
#=GS EP153_ASFB7/12-146          AC Q65150.1
#=GS A0A2K6MYZ3_RHIBE/6-123      AC A0A2K6MYZ3.1
#=GS Q77L25_MEHV1/3-193          AC Q77L25.1
#=GS V008_FOWPN/5-156            AC P14370.1
#=GS A0A2R8ZLF0_PANPA/12-231     AC A0A2R8ZLF0.1
#=GS A0A1R3T5D7_9ALPH/9-197      AC A0A1R3T5D7.1
#=GS A0A194PVR5_PAPXU/2413-2524  AC A0A194PVR5.1
#=GS A0A452QIG9_URSAM/5-148      AC A0A452QIG9.1
#=GS A0A0L0BR94_LUCCU/142-235    AC A0A0L0BR94.1
#=GS A0A3Q7S032_VULVU/15-172     AC A0A3Q7S032.1
#=GS Q6VZ40_CNPV/2-153           AC Q6VZ40.1
#=GS A0A1X9T5H3_9VIRU/50-214     AC A0A1X9T5H3.1
#=GS A0A1U7T7L2_TARSY/7-157      AC A0A1U7T7L2.1
#=GS B4QV10_DROSI/133-235        AC B4QV10.1
#=GS EV45_HHV2H/5-171            AC P89465.1
#=GS B4NID8_DROWI/163-263        AC B4NID8.1
#=GS EV45_PSHV1/50-296           AC Q6UDL6.1
#=GS B4K8Y9_DROMO/162-259        AC B4K8Y9.1
#=GS A0A3Q0IPR7_DIACI/4-82       AC A0A3Q0IPR7.1
#=GS A0A1U7SQE5_TARSY/12-157     AC A0A1U7SQE5.1
O56871_ILTV/33-274                     ..........................................................TPSEDQRSHLEKMMAELPFEVRAILE.DEPSVCSSTS..S.STTSTYSP...HPSgelhsmrpen.................tggqywkackvILLIL.LGIFL...G...L.L......IFM.F.V..I..S....T..VMA.................F.A..LP...N.S...T...W......E..G........G...LCPP.DWIQHLDSC.YRAGGGPP..........qDTYENAKLSC.RALGG.K..I..A..S...SS..K...A..I..G...F..LTIL.....D...R.....L...F.....Y.W..S..G..ST.SPQGlwwaddggk.............canvyfinsIHDDST.ASLST.QKMS.V.A.LV..ENl..qCSGTAGVICYMSPAISPALRYIKALRVALSF...............................................................................................
A0A1I8QBD3_STOCA/127-222               .....................................................ysdeq--------------------------.----------..-.--------...---......................................-----.-----...-...-.-......---.-.-..-..-....-..---.................-.-..--...-.-...-...-......-..-........N...FCPE.HWISFRQTC.YRFIRSPK...........RNWMEAKKIC.KAYNS.E..L..I..N...VD..N...I..D..K...H..AFVL.....KqliM.....Q...N.....Q.R..Q..S..RF.WTSArqtg.......................pnswVND---.-----.----.-.-.--..--....-------------------------------dnspflmidda....................................................................................
J9QYP6_9ALPH/2-157                     ...............................................radaaagackt--------------------------.----------..-.--------...---......................................----V.AAAVV...V...L.V......LGS.L.L..T..I....A..VVA.................L.A..LP...N.S...A...W......T..T........L...PCAP.GWMELGLGC.VSGESALV...........-PFRQAASNC.SA-PG.T..L..I..P...SN..A...A..A..A...M..ALML.....R...T.....Y...A.....R.N..P..I..PY.IW--...............................VRNDGV.KACVR.VADG.M.P.GI..NE...sCAEQAARVCHYYRSPGRVAQFVLRVRGALGL...............................................................................................
A0A2K5KQ70_CERAT/5-123                 .....................pdlenldedgytqlhfdsrsntriavvsekgscvasp--------------------------.----------..-.--------...---......................................-----.PWRLI...A...V.I......LGI.L.C..L..V....I..LVI................aV.V..LG...T.M...G...V......L..S........S...PCPP.NWIIYEKSC.YLFSPSLN...........-SWDGSKRQC.SQLGS.N..L..I..K...ID..S...S..K..E...L..I---.....-...-.....-...-.....-.-..-..-..--.----...............................------.-----.----.-.-.--..--....-------------------------------sdqn...........................................................................................
A0A261BNF9_9PELO/3-150                 ..................................fatslifvtivllvsgvsgnrrfg--------------------------.----------..-.--------...---......................................-----.-----...-...-.-......---.-.-..-..-....-..---.................-.-..--...-.-...-...F......G..V........K...TCPK.GWLQFQRHC.YIRQPDTL...........-DFKGAMESC.ARRGA.T..L..F..Q...FN..S...T..F..E...F..AAVR.....N...L.....F...P.....D.Y..M..F..-T.WLQAeieeelew..............lyepyeekiNGKNSV.ATCIA.FYSS.P.T.KS..YNyyypCTSRFHSICEK--------------------plds...........................................................................................
Q77Q60_9ALPH/3-192                     ..........................................................SPTPEDDRDLVVVRGRLRM-------.----MDNGAE..H.DRERR-SY...TAW......................................-PHLC.CGCTI...G...I.I......LTM.F.V..I..A....T..TLLla.............slF.A..FS...Y.M...S...L......E..S........G...TCPK.EWIGLGYSC.MRVAGNNA...........-TELEALDMC.AQHNS.K..L..V..D...FT..N...A..K..T...L..VEAI.....V...P.....F...G.....S.T..N..A..SF.GNIF...............................RLRDSR.STCIL.PTIG.G.P.IS..VD....CPRTCSVVCQRPRPLSTAASIIRDARIYLRL...............................................................................................
A0A3Q0JHC2_DIACI/580-708               ............rmsspaitfqmgeekefksgspalysasttlllvmsstlyifvafp--------------------------.----------..-.--------...---......................................-----.-----...-...-.-......-TM.S.L..I..S....S..CLFifvs.........fhsvF.S..QT...I.D...E...L......E..L........-...RCPQ.HWVQYRDSC.YRFVKSPL...........KTRNDAKLNC.KSLDS.D..L..A..N...VN..D...A..-..-...-..----.....-...-.....-...-.....-.-..-..-..--.----...............................------.-----.----.-.-.--..--....-------------------------------dehgfimyqlf....................................................................................
A0A194REM0_PAPMA/2411-2525             .......................................................nlt--------------------------.----------..-.--------...---......................................-----.-----...-...-.-......---.-.-..-..-....-..---.................-.-..--...-.-...V...L......G..G........G...KCPP.GWDAVAGTC.YMYVGAPM...........-TYEQARLFClSDNAS.M..P..Y..V...SG..N...Y..E..A...L..YEFI.....R...R.....Q...S.....Q.W..F..Q..-Y.GDRVw.............................vNHIDYV.TQCTS.FAFS.A.I.EI..TD....CYQKNAFICEIVRSIGS--------------ing............................................................................................
B4JY64_DROGR/157-257                   ......................................................tden--------------------------.----------..-.--------...---......................................-----.-----...-...-.-......---.-.-..-..-....-..---.................-.-..--...-.-...-...-......-..-........N...FCPE.HWISYRQTC.YRFIRSPK...........RNWAEAKKIC.KAYTS.D..L..I..N...VD..N...V..D..K...H..AFIL.....T...N.....L...I.....L.Q..N..Q..RQ.NRFFisarq....................tgpqnwVNDDST.Q----.----.-.-.--..--....-------------------------------lvqiedsfafdeq..................................................................................
A0A3Q0ECY1_TARSY/6-169                 ....iiyselnlpqnpksqernsksnkssilvteqeityaelslqtasqdlldndktf--------------------------.----------..H.SKDLSSPP...EKL......................................IAGIL.GIICL...A...L.I......VTM.V.T..I..V....I..ILF.................Y.N..V-...-.S...S...A......Y..N........C...SCPE.EWFTYSNSC.YYMGKKTK...........-TWDESMMAC.ASMNS.S..L..L..-...--..-...-..-..-...-..----.....-...-.....-...-.....-.-..-..-..--.----...............................------.-----.----.-.-.--..--....-------------------------------ytddeemkflaslvheawigvsrnssd....................................................................
A0A1U7TGV5_TARSY/6-157                 ........iiyselnlppnqknqernsksnkssilvseqeityvelslqtvsqdlldn--------------------------.----------..-.--------...--Dktflskd.......................lssapeklIAGIL.GIICL...A...L.I......VTM.V.T..I..V....T..VLStetqe.......qtnsfL.N..ES...K.Q...K...A......Y..N........G...SCPE.EWFTYSNSC.YFIGKETK...........-TWDESMMTC.ASMNS.N..L..-..-...--..-...-..-..-...-..----.....-...-.....-...-.....-.-..-..-..--.----...............................------.-----.----.-.-.--..--....-------------------------------lyid...........................................................................................
Q14WA2_9VIRU/25-164                    .............................................deeehveiievkd--------------------------.---EEEESDR..V.VYKKIKET...HPC......................................---FM.IGLTW...G...W.A......MAA.L.F..F..I....G..TVL.................V.T..VQ...Q.S...Q...C......M..S........A...RCPE.EWVQKGNMCfVERVYENI...........-TCIKAKTHC.AQLQQ.R..L..K..K...PR..D...V..K..V...I..LPTY.....D...-.....-...-.....-.-..-..-..--.----...............................------.-----.----.-.-.--..--....-------------------------------sdnitvwdwaipscktnthdhvar.......................................................................
I1V8C8_9ALPH/19-218                    ..........................................................TAAMDVQAPPLPTKTVPVFAPPLPTP.PTPTECVYTK..R.RRPKRKAK...CRC......................................LFFTM.GMFAL...G...V.L......MTT.A.I..L..V....S..TFI.................L.T..VP...M.G...A...L......R..T........A...PCPA.ETFGLGDEC.IRPVLLNTs........ntSNISGVGAVC.EDYSE.M..A..A..P...ND..T...A..G..L...I..MSLL.....D...C.....I...N.....V.G..Y..N..EF.VMNKl.............................nLNDTQL.AHCNV.SSFV.E.-.--..--....CSNKGVAVCYAARPLSPLGELIYKTRQALRL...............................................................................................
H9J6Q7_BOMMO/2351-2463                 ......................................................nnlt--------------------------.----------..-.--------...---......................................-----.-----...-...-.-......---.-.-..-..-....-..---.................-.-..--...-.-...V...L......G..G........G...KCPP.GWDALAGTC.YMYVGAPM...........-TYDEARQFClSDNAS.M..P..Y..V...TG..K...Y..E..V...L..YDFI.....H...R.....Q...N.....Q.W..F..Q..-Y.GDRVw.............................vNHIDYV.TQCTS.FAFS.S.V.EI..TD....CNQKNAFICEIDP------------------kivi...........................................................................................
A0A1X9T5G1_9VIRU/100-208               ................................................appknlqgnt--------------------------.----------..-.--------...---......................................-----.-----...-...-.-......---.-.-..-..-....-..---.................-.-..--...-.-...-...-......-..-........C...FCPD.GWFTSENQC.LRLIDEKL...........-TYAEAKNKC.DALNM.Q..M..I..T...RN..A...H..L..G...G..NQLA.....T...T.....Q...F.....T.V..P..I..II.WT--...............................ETEDKV.CQTIN.TVHK.T.Q.--..QDt..hCDEKHPYVCKTN-------------------irf............................................................................................
A0A443SMF6_9ACAR/1-94                  ......................................................myrl--------------------------.----------..-.--------...---......................................-----.-----...-...-.-......---.-.-..-..W....S..TLV.................L.V..IA...F.S...N...F......A.aS........D...ECPK.NWVDYKTSC.YRFSRSPR...........KTVVDAEEIC.RKYGS.T..L..V..S...VN..S...V..D..E...H..FFII.....S...W.....L...-.....-.-..-..-..--.----...............................------.-----.----.-.-.--..--....-------------------------------kendpqhlkwltsgneqan............................................................................
A0A0Y0A759_9ALPH/6-170                 ...............................................edypylpldqh--------------------------.----------..-.TPNSRTSA...AAW......................................---VC.GGIVV...G...G.L......LTL.C.L..I..-....-..--I.................L.A..TP...S.S...S...W......S..L........P...ACEA.GWTELNNGC.ITWDSTPV...........-EYSQATQTC.GG-RS.T..L..I..P...RI..P...A..R..Q...L..VNIL.....R...V.....A...T.....P.G..F..A..AN.N-MW...............................IRGDGI.KTCLQ.LSTG.D.G.GV..SQ...tCDDLALCVCYYPRDLSGFAQIAIAVRRTLNL...............................................................................................
A0A068EHX7_9POXV/11-145                ........................................................kh--------------------------.----------..-.--------...---......................................-----.-----...G...I.L......AIA.F.I..I..L....L..LVI.................I.L..LD...V.D...R..dK......Y..L........I...SCDK.KWIEFNNLC.YFISKDKL...........-NWNDSMAVC.NNLG-.-..-..-..S...NG..N...Y..I..N...L..NMTS.....G...I.....L...N.....T.-..S..N..NY.WIKTv............................deVDCTNT.ATCNF.LYSN.V.I.GC..DI....CNIEKFYVCVKP-------------------igkinlfnffve...................................................................................
Q7T5D3_CHV1/7-173                      ...........................................erlgyrplsaggraa--------------------------.----------..-.--------...AAA......................................RLSAV.AWLIA...G...V.V......VGV.V.V..V..L....A..GLI.................L.A..VP...R.A...A...W......G..L........A...PCGA.GWTEFNAGC.LSWDPTPV...........-DHELAAGGC.RA-PA.T..L..I..P...RT..A...A..K..Q...L..AAVA.....G...V.....G...A.....R.A..S..G..AY.WW--...............................VDGDGI.KACLR.PSDG.A.S.GI..DQ...fCEGPALRICYHPRSPGGFVTFVLSARGALGL...............................................................................................
A0A482X9C4_LAOST/3-115                 .........................................................k--------------------------.----------..-.--------...---......................................-----.-----...-...-.-......IFI.L.I..L..L....A..TFE.................L.C..GT...Q.T...S...Q......E..G........GsewTCPQ.HWHKFQNSC.YRFIKSPL...........RNRNDARRNC.QAYVS.D..L..V..S...IN..N...L..E..E...L..SFIV.....N...R.....L...I.....Q.E..D..-..--.----...............................------.-----.----.-.-.--..--....-------------------------------pqhrrwyigaheqspgywvnegdstalte..................................................................
A0A2A4JQC2_HELVI/2534-2647             .....................................................mnnqt--------------------------.----------..-.--------...---......................................-----.-----...-...-.-......---.-.-..-..-....-..---.................-.-..--...-.-...V...L......G..G........G...KCPP.GWDAVAGTC.YMYVGAPM...........-TYEEARLFClSDNAS.M..P..Y..V...TG..N...Y..A..A...L..YEFI.....N...R.....Q...N.....Q.W..F..Q..-Y.GDRVw.............................vNHIDYV.TQCTS.FAFS.N.V.EI..TD....CNQKNAFICEIDP------------------kimi...........................................................................................
A0A067R1K6_ZOONE/6-73                  ......................................wflilalpcvisqirtldse--------------------------.----------..-.--------...---......................................-----.-----...-...-.-......---.-.-..-..-....-..---.................-.-..--...-.-...-...-......-..-........M...RCPE.HWVKFQLSC.YRFIKSPL...........RNRNDAKKNC.EAYQS.D..L..V..S...VN..-...-..-..-...-..----.....-...-.....-...-.....-.-..-..-..--.----...............................------.-----.----.-.-.--..--....-------------------------------tpdeh..........................................................................................
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B4I3N0_DROSE/133-233                   .....................................................tdedn--------------------------.----------..-.--------...---......................................-----.-----...-...-.-......---.-.-..-..-....-..---.................-.-..--...-.-...-...-......-..-........-...FCPE.HWVSFRQTC.YRFIRSPK...........RNWAEAKKIC.KAYNA.D..L..I..N...VD..N...V..E..K...H..SFIL.....K...N.....L...I.....L.Q..N..Q..RQ.NRFFisarq....................tgplnwVNDDNT.-----.----.-.-.--..--....-------------------------------qlvqiedsfsmdeq.................................................................................
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EP153_ASFP4/12-145                     ...............................................dkncekkildd--------------------------.----------..-.--------...--C......................................TTIKI.CYILI...G...I.L......IGT.N.M..ItlI....Y..NFIfw.............dhY.M..TC...N.K...K...D......K..M........F...YCPK.DWVGYNNVC.YYFNNDSK...........-NYTTATNSC.KQLNS.T..L..A..N...ND..T...-..-..N...L..LNLT.....K...V.....Y...H.....H.D..K..L..-Y.WVNY...............................SLNDNF.S----.----.-.-.--..--....-------------------------------lslrnstyekrsk..................................................................................
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Q69365_FHV1/7-189                      ..........................................................TSQPLVEIPLVDMEPQPSIHSNEPNP.PNKMLTTAIS..S.RRSGI---...---......................................FLFSL.GMFFF...G...V.I......LTA.T.I..I..V....C..TFI.................F.T..IP...V.D...M...L......Q..M........P...RCPE.ETVGIKNCC.IRPIRRHV...........KSHQDLVATC.AEYME.Q..P..A..T...AS..A...V..G..A...L..IPLL.....D...I.....F...N.....G.D..G..I..--.----...............................STNDSL.YDCIL.SDEK.K.-.--..--....SCNTSMAVCQSTYLPNPLSDFIMRVRQIFS-g..............................................................................................
A0A1I8NGE1_MUSDO/131-223               .......................................................edn--------------------------.----------..-.--------...---......................................-----.-----...-...-.-......---.-.-..-..-....-..---.................-.-..--...-.-...-...-......-..-........-...FCPE.HWISYRQTC.YRFIRSPK...........RNWMEAKKIC.KAYNA.E..L..I..N...VD..N...V..D..K...H..AFVL.....K...Q.....LilqN.....Q.R..Q..N..RF.WTSArqtg.......................pnswV-----.-----.----.-.-.--..--....-------------------------------nddnspflmveds..................................................................................
A0A1S3QRB6_SALSA/7-107                 ...............................................vgpmllagdsm--------------------------.----------..-.--------...---......................................-----.-----...T...M.L......TSL.L.I..L..S....A..TFA.................L.G..DA...N.S...I...L......E..E........D...LCPS.GWTKYGSRC.LMFVKTTR...........-SWPEAERHC.VSLGD.K..L..V..S...VP..N...V..V..K...-..----.....-...-.....-...-.....-.-..-..-..--.----...............................------.-----.----.-.-.--..--....-------------------------------ylganlasvhsseedeflqa...........................................................................
A0A2J7QMK8_9NEOP/5-72                  ...........................................gwflilalpcvasqi--------------------------.----------..-.--------...---......................................-----.-----...-...-.-......---.-.-..-..-....-..---.................-.-..--...-.R...T...L......D..S.......eM...RCPQ.HWVRFQLSC.YRFIKSPL...........RNRNDARKNC.EAYQA.D..L..V..S...VN..-...-..-..-...-..----.....-...-.....-...-.....-.-..-..-..--.----...............................------.-----.----.-.-.--..--....-------------------------------tpde...........................................................................................
O39257_EHV4/19-218                     ..........................................................TAAGNDQAPQLPTKTVLGFTPPLPTL.PQPTELVYTK..R.RRPKRRSR...CRC......................................LCFTM.GMFAM...G...V.L......MTT.T.L..L..V....S..TFV.................L.T..VP...M.V...A...L......R..T........A...PCPA.QTFGLGDEC.VRPVSLDAy........nsSNSSEIGAVC.GAYSE.M..P..A..P...DN..T...T..V..L...I..MNLL.....D...C.....L...N.....I.G..I..N..ES.AGEKl.............................nLTDTPL.ANCNF.SQNS.V.-.--..--....CSRKRVSVCYAARPLSPLGELIYKARQALRL...............................................................................................
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CONT_DROME/133-233                     .....................................................tdedn--------------------------.----------..-.--------...---......................................-----.-----...-...-.-......---.-.-..-..-....-..---.................-.-..--...-.-...-...-......-..-........-...FCPE.HWVSFRQTC.YRFIRSPK...........RNWAEAKKIC.KAHNA.D..L..I..N...VD..N...V..E..K...H..SFIL.....K...N.....L...I.....L.Q..N..Q..RQ.NRFFisarq....................tgplnwVNDDNT.-----.----.-.-.--..--....-------------------------------qlvqiedsfsmdeq.................................................................................
Q14W75_9VIRU/14-199                    ....................................vsldendlgkeadsyvnenyig------------------------KE.PTPTKDEEAA..E.KPKEKIPG...TPK......................................--ETK.HCISL...G...G.V......LCI.V.A..I..V....I..CFFma............maaM.T..AG...V.A..vM...Y......S..G........Q...QCED.KWTAVGQRC.VRSFIGHL...........GTFEYARDFC.EQESA.R..L..Y..N...YN..E...D..K..S...L..-ELI.....G...I.....L...E.....N.G..K..E..FY.WA-E...............................RFGKPI.CTMFN.VTTK.V.-.--..--....C------------------------------pklnrvfcirktleesrkcsc..........................................................................
A0A087T3V6_9ARAC/12-93                 ..............................................amlktalfivif--------------------------.----------..-.--------...---......................................-----.-----...-...-.-......---.-.-..-..-....-..---.................H.S..IS...Y.S...V...L......-..C........Q...TCPK.EWVDFSDSC.YKFTRTPL...........RTRDEAQDIC.RSYNT.D..L..V..G...VN..-...-..-..-...-..----.....-...-.....-...-.....-.-..-..-..--.----...............................------.-----.----.-.-.--..--....-------------------------------tleehnfivgwlrendpq.............................................................................
O89243_9ALPH/3-191                     ..........................................................SPTPEDDPRLGPVRGLLRM-------.----MD-ETT..S.ERHKR-SR...SGC......................................-PRLL.CGCTI...G...I.A......LTV.F.V..I..T....A..TVVla.............slF.A..FS...Y.M...S...L......E..S........G...TCPH.EWIGLGYSC.MRAMGSNA...........-TELEALDTC.SRHNS.K..L..V..D...FT..H...A..K..I...L..IEAI.....A...P.....F...A.....S.T..D..A..NS.SNVF...............................RLRDSR.TTCVR.PTAA.G.P.VA..VD....CPRTCTAICQRPRPLSIVASIIRDARTSLRL...............................................................................................
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D3YPA9_HHV1/4-171                      ..........................................rasehayrplgpgtpp--------------------------.----------..-.MRARL--P...AAA......................................-----.-WVGV...G...T.I......IGG.V.V..I..I....A..ALV.................L.V..PS...R.A...S...W......A..L........S...PCDS.GWHEFNLGC.ISWDPTPM...........-EHEQAVGGC.SA-PA.T..L..I..P...RA..A...A..K..Q...L..AAVA.....R...V.....Q...S.....A.R..S..S..GY.WW--...............................VSGDGI.RACLR.LVDG.V.G.GI..DQ...fCEEPALRICYYPRSPGGFVQFVTSTRNALGL...............................................................................................
A0A212EXL4_DANPL/2339-2452             .......................................................nna--------------------------.----------..-.--------...---......................................-----.-----...-...-.-......---.-.-..-..-....-..---.................-.-..--...-.S...V...L......G..G........G...KCPP.GWVSLSGTC.YMYIGAPM...........-TYHEARAFClSDNAS.M..P..Y..V...NG..N...Y..D..D...L..YEFI.....H...S.....Q...N.....Q.W..V..R..-Y.GDRVw.............................vNHIDYV.TQCTS.FAYS.D.I.EI..TD....CGQKNAFICEIDPKIS---------------id.............................................................................................
A0A2T7NRD8_POMCA/1-146                 ........................................................ml--------------------------.----------..-.--------...---......................................-----.-----...-...-.-......-CH.V.I..I..V....A..GAVl...............fL.T..YG...D.V...T...Q......A..T........G...GCGS.DWVQLNSAC.YYVSRTSA...........-NWSTAQTYC.RENGG.T..L..L..S...SN..Y...Q..K..E...P..IQIL.....W...N.....M...T.....R.E..N..Q..QW.WVEMqktsavta...............ipwdrsesTDGEDT.RDCAE.MDYS.G.-.LL..NDv..qCNSSLYFVCEK--------------------raernaim.......................................................................................
A0A2K5TXM0_MACFA/20-183                ......................qqrklkgnkssisgteqkifqvelnlqnassdhqgn--------------------------.DKTYHCKGLL..P.PPEKL--T...AEV......................................LGIIC.IVLMA...T...V.L......KTI.V.L..I..P....C..IGVle............qnnF.S..LNtriQ.K...A...Y......D..C........G...HCPE.EWITYTNSC.YYIGKEKR...........-TWEESLLTC.ASKNS.S..L..L..S...--..-...-..-..-...-..----.....-...-.....-...-.....-.-..-..-..--.----...............................------.-----.----.-.-.--..--....-------------------------------idneeemqllgslsvlswvgvsavsa.....................................................................
A0A2H2I614_CAEJA/52-146                .........................................................i--------------------------.----------..-.--------...---......................................-----.-----...-...-.-......---.-.-..-..-....-..---.................-.-..LP...A.A...S...V......C..G........P...KCPS.NWIFFGSHC.YGKLQGPA...........-NYYQFADEC.ERRGG.Q..I..A..D...NN..F...T..-..V...L..DTFL.....R...V.....A...F.....-.-..-..-..--.----...............................------.-----.----.-.-.--..--....-------------------------------eeynlnhiwikreardgmsadelsegncvava...............................................................
A0A2K6C8E0_MACNE/20-183                ......................qqrklkgnkssisgteqkifqvelnlqnassdhqgn--------------------------.DKTYHCKGLL..P.PPEKL--T...AEV......................................LGIIC.IVLMA...T...V.L......KTI.V.L..I..P....C..IGVle............qnnF.S..LNtriQ.K...A...Y......D..C........G...HCPE.EWITYTNSC.YYIGKEKR...........-TWEESLLTC.ASKNS.S..L..L..S...--..-...-..-..-...-..----.....-...-.....-...-.....-.-..-..-..--.----...............................------.-----.----.-.-.--..--....-------------------------------idneeemqllgslsvlswvgvsavsa.....................................................................
A0A087ZZ67_APIME/13-80                 ........................................ilsyntfaqnilyeelyq--------------------------.----------..-.--------...---......................................-----.-----...-...-.-......---.-.-..-..-....-..---.................-.-..--...-.-...-...-......-..-........-...HCPQ.HWIKFQESC.YRFIKSPI...........KERQDAKRNC.EAYQS.D..L..I..T...I-..-...-..-..-...-..----.....-...-.....-...-.....-.-..-..-..--.----...............................------.-----.----.-.-.--..--....-------------------------------nsleehgfi......................................................................................
EV45_HHV11/4-171                       ..........................................rasehayrplgpgtpp--------------------------.----------..-.MRARL--P...AAA......................................-----.-WVGV...G...T.I......IGG.V.V..I..I....A..ALV.................L.V..PS...R.A...S...W......A..L........S...PCDS.GWHEFNLGC.ISWDPTPM...........-EHEQAVGGC.SA-PA.T..L..I..P...RA..A...A..K..Q...L..AAVA.....R...V.....Q...S.....A.R..S..S..GY.WW--...............................VSGDGI.RACLR.LVDG.V.G.GI..DQ...fCEEPALRICYYPRSPGGFVQFVTSTRNALGL...............................................................................................
R7UI05_CAPTE/1-86                      ........................................................ms--------------------------.----------..-.--------...---......................................-----.-----...-...-.-......--T.M.L..L..V....A..LLI................aF.A..GC...P.S...S...S......L..T........A...QCPA.EWTSIGDNC.YQFSENDL...........-TSEEAREAC.KKTGG.D..L..V..A...AE..E...A..S..H...V..LNAM.....-...-.....-...-.....-.-..-..-..--.----...............................------.-----.----.-.-.--..--....-------------------------------lkmdirqdfvagk..................................................................................
A0A340YDA9_LIPVE/2-146                 ...................................................tveeasa----------------------KILQ.TDPTSRESME..E.GRSGKDLQ...RKClpi...............................tspiIPLYC.CIIII...M...V.L......ATI.V.M..V..L....S..TFLa..............vrN.T..KP...V.S...Y...V......L..Y........V...TCPK.EWIGFGSKC.FYFSE---...........----------.-----.-..-..-..-...--..-...-..-..-...-..----.....-...-.....-...-.....-.-..-..-..--.----...............................------.-----.----.-.-.--..--....-------------------------------dtrnwtfsqafctsleavlgqfeteeelnflkrykgpsdhwiglrress..............................................
A0A2A3EGS0_APICC/14-79                 .........................................lsyntfaqnilyeelyq--------------------------.----------..-.--------...---......................................-----.-----...-...-.-......---.-.-..-..-....-..---.................-.-..--...-.-...-...-......-..-........-...HCPQ.HWIKFQESC.YRFIKSPI...........KERQDAKRNC.EAYQS.D..L..I..T...I-..-...-..-..-...-..----.....-...-.....-...-.....-.-..-..-..--.----...............................------.-----.----.-.-.--..--....-------------------------------nsleehgf.......................................................................................
E2IUC5_SHV1/4-169                      ........................................npldnlrsldepeerprr--------------------------.----------..-.------SG...CAI......................................---GT.AAAVG...G...V.F......LGA.L.A..L..A....A..ALV.................L.A..AP...G.S...A...W......T..L........G...PCSP.GWIELNSAC.LADELHIA...........-TLSEARSRC.GP-SD.A..L..P..P...PE..V...A..R..Q...L..GRIA.....R...L.....G...N.....L.T..L..E..HP.VW--...............................VAGDGV.AACIH.QGRV.A.-.--..AG...gCPNQALGLCYRPRPEGVLRWVIFAARRYVGL...............................................................................................
A0A060Q0W5_9ALPH/6-169                 ..........................................aqysyqplhapqpvsr--------------------------.----------..-.--------...---......................................-PLAL.LWLCL...G...A.A......VGV.L.I..A..M....A..LLI.................L.A..TP...S.A...T...W......T..L........P...ACEA.GWTEFNTGC.LSWNPTPM...........-PYTEAQQGC.PA-PA.S..L..I..P...RN..W...A..R..Q...L..ATIL.....N...L.....P...A.....P.P..P..A..TT.VW--...............................LAGDGL.KACFH.LHNG.A.S.GL..DS...eCDPTALRVCFYSRSLGGFVQFAVMVRRALNL...............................................................................................
A0A2K5UXV0_MACFA/6-123                 ......................dlenldedgytqlhfdsrsntriavvsekgscvasp--------------------------.----------..-.--------...---......................................-----.PWRLI...A...V.I......LGI.L.C..L..V....I..LVI................aV.V..LG...T.M...G...V......L..S........S...PCPP.NWIIYEKSC.YLFSPSLN...........-SWDGSKRQC.SQLGS.N..L..I..K...ID..S...S..K..E...L..I---.....-...-.....-...-.....-.-..-..-..--.----...............................------.-----.----.-.-.--..--....-------------------------------sdqn...........................................................................................
EV45_EHV1B/11-211                      ..........................................................TATVDAQAPPLPTKTVPVFAPPLSTP.PQPNELVYTK..R.RRTKRKAK...CRC......................................LFFTM.GMFAL...G...V.L......MTT.A.I..L..V....S..TFI.................L.T..VP...I.G...A...L......R..T........A...PCPA.ETFGLGDEC.VRPVLLNAss.......ntRNISGVGAVC.EEYSE.M..A..A..S...NG..T...A..G..L...I..MSLL.....D...C.....L...N.....V.G..D..S..ES.VMNKl.............................nLDDTQL.AYCNV.PSFA.E.-.--..--....CYTKGFGVCYAARPLSPLGELIYKARQALRL...............................................................................................
NKG2A_PANTR/12-231                     ...............nlppnpkrqqrkpkgnkssilateqeityaelnlqkasqdfqe-------------------------N.DKTYH-----..-.--------...--Ckdlpsa.........................peklivgILGII.CLILM...A...S.V......VTI.V.V..I..P....S..TLIqrhn.........nsslN.T..RT...Q.K...A...R......H..C........G...HCPE.EWITYSNSC.YYIGKERR...........-TWEESLLAC.TSKNS.G..LlsI..D...NE..E...E..M..K...F..LSII.....S...P.....S...-.....-.-..-..-..--.----...............................------.-----.----.-.-.--..--....-------------------------------swigvfrnsshhpwvtinglafkheikdsdnaelncavlqvnglksaqcgssiiyhckh....................................
A0A452QIG1_URSAM/4-144                 ...........................................qgvtyaelnivknsk----RQQRKAKGTKSSTSVTEQEITY.AELN------..-.--------...--Lqtasqdlqgngkn............shckglflpliaeILGII.CLVLM...S...T.V......VTI.A.V..I..T....C..KFV................wI.I..SP...N.L...S...P......A..Y........H...CCPK.EWLAHSNNC.YYISTEKKt.........wNESSIILYVC.GQ---.-..-..-..-...--..-...-..-..-...-..----.....-...-.....-...-.....-.-..-..-..--.----...............................------.-----.----.-.-.--..--....-------------------------------qv.............................................................................................
E0VHE2_PEDHC/68-119                    .....................................................seyel--------------------------.----------..-.--------...---......................................-----.-----...-...-.-......---.-.-..-..-....-..---.................-.-..--...-.-...-...-......-..-........-...KCPQ.HWEQYQQSC.YRFIKSPM...........RAREDAKKNC.EAYHS.D..L..V..S...VN..-...-..-..-...-..----.....-...-.....-...-.....-.-..-..-..--.----...............................------.-----.----.-.-.--..--....-------------------------------sleeh..........................................................................................
A0A210QJ01_MIZYE/2-82                  .......................................................fwi--------------------------.----------..-.--------...---......................................-----.-----...-...-.-......---.-.-..-..-....-..TLL.................L.T..AS...P.I...W...G......Q..T........Y...DCPQ.DWFEHGDHC.YHFSFNPL...........KTYLQAKELC.EDYGA.A..L..L..S...IE..T...T..-..-...-..----.....-...-.....-...-.....-.-..-..-..--.----...............................------.-----.----.-.-.--..--....-------------------------------sedvfiknwlsqrdqaknlw...........................................................................
A0A154PRQ2_DUFNO/1-84                  .....................................................myhiq--------------------------.----------..-.--------...---......................................-----.-----...-...I.V......LII.I.L..V..V....S..TGI.................F.T..QN...I.L...Y...G......E..T.......lY...QCPQ.HWIKFQESC.YRFIKSPI...........RERDEARKNC.QAYQS.D..L..I..T...IN..S...V..-..-...-..----.....-...-.....-...-.....-.-..-..-..--.----...............................------.-----.----.-.-.--..--....-------------------------------eehgfvlyql.....................................................................................
Q66077_9ALPH/1-174                     ................................................maqlvltdip---------LE------------DVE.NKNTSSDEET..T.NLNQKKST...CQC......................................LCVTL.GFFAA...G...I.L......LTI.A.A..I..I....F..TFI.................F.T..VP...L.E...M...L......G..S........I...NCPP.STFGIDNVC.IEPIKKSI...........NSYSELSKIC.YDRLS.N..P..I..N...QS..T...I..N..S...L..LTVL.....N...M.....F...A.....D.-..-..-..--.----...............................KNYENV.YNCNT.MSEK.-.-.--..--....TCNSSIAICQTNHPLSSLGNFVIKIRKIFGF...............................................................................................
A0A2K6FPM2_PROCO/3-138                 ..........................................nqrviysemnlaknsk--------------------------.----------..-.-RKRRKSK...DTKssiseteqeityvelnl...qnaaqdlpgndkyyqckdLLFTP.EKLIA...G...I.L......GII.C.L..V..V....T..TGI.................I.T..CN...L.S..lA...Y......H..C........G...RCPE.EWFTYSTNC.YYISKEL-...........KTWDESVTAC.ASNNS.N..L..-..-...--..-...-..-..-...-..----.....-...-.....-...-.....-.-..-..-..--.----...............................------.-----.----.-.-.--..--....-------------------------------ly.............................................................................................
A0A1S3CTW1_DIACI/3-88                  .............................................lissclfifvsfh--------------------------.----------..-.--------...---......................................-----.-----...-...-.-......---.-.-..-..-....-..-SV.................F.S..QT...I.D...E...L......E..L........-...RCPQ.HWVQYRDSC.YRFVKSPL...........KTRNDAKLNC.KSLDS.D..L..A..N...VN..D...A..-..-...-..----.....-...-.....-...-.....-.-..-..-..--.----...............................------.-----.----.-.-.--..--....-------------------------------dehgfimyqlfwqdpqr..............................................................................
F8TC43_9ALPH/3-191                     ..........................................................SPTPEDDRDLVAVRGLLRM-------.----MD-ETT..S.ERHKR-SR...SGC......................................-PRLL.CGCTI...G...I.A......LTV.F.V..I..T....A..TVVla.............slF.A..FS...Y.M...S...L......E..S........G...TCPH.EWIGLGYSC.MRAMGSNA...........-TELEALDTC.SRHNS.K..L..V..D...FT..H...A..K..I...L..IEAI.....A...P.....F...A.....S.T..D..A..NS.SNVF...............................RLRDSR.TTCVR.PTAA.G.P.VA..VD....CPRTCTAICQRPRPLSIVASIIRDARTSLRL...............................................................................................
A0A2A4JNJ3_HELVI/2524-2637             .....................................................mnnqt--------------------------.----------..-.--------...---......................................-----.-----...-...-.-......---.-.-..-..-....-..---.................-.-..--...-.-...V...L......G..G........G...KCPP.GWDAVAGTC.YMYVGAPM...........-TYEEARLFClSDNAS.M..P..Y..V...TG..N...Y..A..A...L..YEFI.....N...R.....Q...N.....Q.W..F..Q..-Y.GDRVw.............................vNHIDYV.TQCTS.FAFS.N.V.EI..TD....CNQKNAFICEIDP------------------kimi...........................................................................................
A0A1V0M8J2_9ALPH/22-216                ........................spvpeselepspepritgelrvdayppcrdasdd--------------------------.----------..-.-----SSL...TKC......................................-ARVC.CGFVL...G...T.L......VTI.V.L..V..AlvafI..VLI.................F.A..FS...Y.T...S...L......E..S........G...VCQA.EWVGLGRLC.LGVASRNA...........-SEYDANTIC.ESAGA.E..V..V..S...LG..T...I..Q..S...L..IDVL.....S...T.....F...T.....RvG..N..I..DF.TGVA...............................RVGGNK.IVCID.ASSS.G.P.TA..IK....CPDRVVVICQRARPLGVPAEIIRRVRVFLGL...............................................................................................
EV45_GAHVM/3-192                       ..........................................................SPTPEDDRDLVVVRGRLRM-------.----MDNGAE..H.DRERR-SY...TAW......................................-PHLC.CGCTI...G...I.I......LTM.F.V..I..A....T..TLLla.............slF.A..FS...Y.M...S...L......E..S........G...TCPK.EWIGLGYSC.MRVAGNNA...........-TELEALDMC.AQHNS.K..L..V..D...FT..N...A..K..T...L..VEAI.....V...P.....F...G.....S.T..N..A..SF.GNIF...............................RLRDSR.STCIL.PTIG.G.P.IS..VD....CPRTCSVVCQRPRPLSTAASIIRDARIYLRL...............................................................................................
A0A077B9A2_9ALPH/8-198                 ....................................slppleelerrigidngsggnk--------------------------.--VAQTAAAP..A.RRERRLGR...CHC......................................CCFTT.GVFVA...G...V.L......AAT.A.V..L..V....G..TFV.................L.S..VP...L.A...A...L......R..A........D...RCPP.HTFGVGEAC.VRPVYQQA...........DDYANLVELC.ARHSE.L..P..A..A...PD..T...M..L..S...L..VRLL.....S...H.....F...T.....A.D..R..G..EF.LQTPs.............................gENLSRI.AECIF.SPSE.A.-.--..--....CRNQRLGVCQAARPLSPLGKLVAGTKQALGL...............................................................................................
A1YZN4_9ALPH/33-223                    ....................wnfgngepintrrnswslgeersrpicydrhgvgcakt--------------------------.----------..-.--------...---......................................ARLIT.IGIVV...G...I.L......IVG.L.V..C..F....F..VGV.................F.A..IP...T.T...A...W......D..T........S...TCHH.GWIGIDTVC.VYAVRLNT...........-IAKDVIGLC.AAVDA.E..P..I..T...VA..N...A..K..T...L..LAAI.....G...E.....Y...A.....N.N..TsiG..ES.LPPI...............................WTNLNG.LHCLR.IDAA.G.-.AK..DD...iCSQTATTVCQKPRPLGSVAGMFRYVRRVFGL...............................................................................................
A0A210QIS8_MIZYE/1-100                 .......................................................mrt--------------------------.----------..-.--------...---......................................-----.-----...-...-.-......-TA.V.V..L..L....C..TLV.................-.-..VG...L.D...S...Q......N..I........G...ECPL.GWFFHGQSC.YEFIKDPL...........ALYEEADKIC.KGKGA.A..L..V..S...VN..S...Y..D..E...H..IFII.....Q...Q.....L...K.....-.-..-..-..--.----...............................------.-----.----.-.-.--..--....-------------------------------aidiakrytwwtsgseiddrvkw........................................................................
A0A3P9CYE8_9CICH/2-130                 .................................................vllsfvrff--------------------------.----------..-.--------...---......................................-----.-----...-...-.-......---.-.-..-..-....-..--I................kF.T..LF...S.L...S...V......T..S........L...QCPP.GWIAIGGSC.YIVRRTGL...........-TWSDALHRC.SD---.-..L..A..A...GS..H...L..A..N...L..KSLE.....D...L.....F...F.....I.S..S..Y..LL.SQNNlll........................lwtgLNDQQVsYQTIY.GATA.S.S.GS..DRl..fCRESVSLVCFWP-------------------tlhq...........................................................................................
E2BBG0_HARSA/4-105                     ........................................................ll--------------------------.----------..-.--------...---......................................-----.-----...-...-.-......---.C.V..V..V....F..SLV.................L.S..LP...V.Y...A...QstfyeeS..T........Y...QCPL.HWIKFQQSC.YRFINSPL...........RSRENARKNC.QAFQS.D..L..L..T...IN..S...V..-..-...-..----.....-...-.....-...-.....-.-..-..-..--.----...............................------.-----.----.-.-.--..--....-------------------------------dehgfviqhfrdndqyhhhrwyigvkqqngi................................................................
A0A1U7TR39_TARSY/16-125                .............................trlhfnsqnitripvisnkgtcaasppwr--------------------------.----------..-.--------...---......................................----L.VAVIL...G...V.L......CLI.T.L..V..I....A..---.................V.V..LG...T.M...G...V......L..N........S...PCPP.NWIIHENSC.YLF-STSL...........DSWNGSKKRC.SQLDS.N..L..L..K...ID..N...S..K..E...L..V---.....-...-.....-...-.....-.-..-..-..--.----...............................------.-----.----.-.-.--..--....-------------------------------snqkhs.........................................................................................
A8XY68_CAEBR/7-175                     .......................mmsaavtlhkgtpfdfevmeivgyiknrredapes--------------------------.----------..-.--------...---......................................--TTI.MKYFI...R...F.L......LTI.L.V..I..T....R..NLA.................A.L..ID...V.W...A...Q......D..E........S...SCPI.GWQIASDQC.VRIVISPA...........-SLKHAKKIC.HHEGG.E..L..M..D...TS..V...I..L..L...L..EDVM.....D...L.....L...Kn...lY.E..N..G..LY.EPTFhvggm.....................gqalnRTDDGN.YKIIT.I---.-.-.--..--....-------------------------------npsshfpficsls..................................................................................
A0A484BNT4_DRONA/162-259               .....................................................tdedn--------------------------.----------..-.--------...---......................................-----.-----...-...-.-......---.-.-..-..-....-..---.................-.-..--...-.-...-...-......-..-........-...FCPE.HWVSFRQTC.YRFIRSPK...........RNWAEAKKIC.KAYTA.D..L..V..N...VD..N...V..E..K...H..AFIL.....K...Q.....L...I.....I.Q..N..Q..RQ.NRFFisarq....................tgpqnwVNDDNT.Q----.----.-.-.--..--....-------------------------------liqiedsfaf.....................................................................................
EP153_ASFB7/12-146                     ...........................................dkncekkilddssti--------------------------.----------..-.--------...---......................................---KI.CYILI...G...I.L......IGT.N.M..ItlI....Y..NFIfw............dnyI.K..CY...R.N...N...D......K..M........F...YCPN.DWVGYNNIC.YYFSNGSF..........sKNYTAASNFC.RQLNG.T..L..A..N...ND..T...-..-..N...L..LNLT.....K...I.....Y...N.....N.Q..S..M..-Y.WVNNt............................viLRGDNK.-----.----.-.-.--..--....-------------------------------ysqkvnytd......................................................................................
A0A2K6MYZ3_RHIBE/6-123                 .....................dlenldedgytqlhfdsrsntriavvsekgscaaspp--------------------------.----------..-.--------...---......................................-----.-WRLI...A...V.I......LGI.L.C..L..V....I..LVI................aV.V..LG...T.M...G...L......L..S........S...PCPP.NWIIYEKSC.YLFSLSLN...........-SWDGSKRQC.SQVGS.N..L..I..K...ID..S...S..K..E...L..I---.....-...-.....-...-.....-.-..-..-..--.----...............................------.-----.----.-.-.--..--....-------------------------------sdqn...........................................................................................
Q77L25_MEHV1/3-193                     ..........................................................SPTPEDDRDLVVVRGRLRM-------.----MDSGTE..T.DREQRHPR...TTW......................................-RSIC.CGCTI...G...M.V......FTI.F.V..L..V....A..AVLlg.............slF.T..VS...Y.M...A...M......E..S........G...TCPD.EWIGLGYSC.MRVAGKNA...........-TDLEALDTC.ARHNS.K..L..I..D...FA..N...A..K..V...L..VEAI.....A...P.....F...G.....V.P..N..A..AY.GEVF...............................RLRDSK.TTCIR.PTMG.G.P.VS..AD....CPVTCTVICQRPRPLSTMSSIIRDARVYLHL...............................................................................................
V008_FOWPN/5-156                       .......................................................lkk--------------------------.----------..-.----QVSE...VSC......................................YAITV.LGILC...L...I.L......FTI.L.V..V..V....T..CKW................yY.A..FP...Y.F...-...-......-..S........K...VCPD.EWIGYNSKC.YYFTINET...........-NWNDSKKLC.DVMDS.S..L..I..R...FD..N...I..E..T...L..NFVS.....R...-.....-...-.....Y.G..K..G..SY.WI--...............................------.-----.----.-.-.--..--....-------------------------------dinqnrkipginfslyyeqgvndicllfdtsniiemscifherticvked.............................................
A0A2R8ZLF0_PANPA/12-231                ...............nlppnpkrqqrkpkgnkssilateqeityaelnlqkasqdfqe-------------------------N.DKTYH-----..-.--------...--Ckdlpsa.........................peklivgILGII.CLILM...A...S.V......VTI.V.V..I..P....S..TLIqrhn.........nsslN.T..RT...Q.K...A...R......H..C........G...HCPE.EWITYSNSC.YYIGKERR...........-TWEESLLAC.TSKNS.G..LlsI..D...NE..E...E..M..K...F..LSII.....S...P.....S...-.....-.-..-..-..--.----...............................------.-----.----.-.-.--..--....-------------------------------swigvfrnsshhpwvtinglafkheikdsdnaelncavlqvnglksaqcgssiiyhckh....................................
A0A1R3T5D7_9ALPH/9-197                 .....................................evskelsndndrldlrgselv--------------------------.----MMNDIQ..E.RSGGTSTT...AAY......................................VCASL.LGIMS...G...I.V......VCA.A.V..I..F....L..VCA.................F.A..VN...P.D...K...W......G..K........D...DCQD.GWIGAGKYC.IRPANLGV...........-TYEEAERAC.AG-MG.K..G..A..S...LT..D...A..D..T...V..RRMI.....D...A.....A...Y.....G.F..G..A..SS.LGPV...............................WLSGKQ.NSCVK.VENG.T.P.NE..AT....CEGTAAAVCIREKPPSKIAGIFLMV------kkfigl.........................................................................................
A0A194PVR5_PAPXU/2413-2524             .......................................................nlt--------------------------.----------..-.--------...---......................................-----.-----...-...-.-......---.-.-..-..-....-..---.................-.-..--...-.-...V...L......G..G........G...KCPP.GWDAVSGTC.YMYVGAPM...........-TYEQARLFClSDNAS.M..P..Y..V...SG..N...Y..E..A...L..YEFI.....R...R.....Q...S.....Q.W..F..Q..-Y.GDRVw.............................vNHIDYV.TQCTS.FAFS.A.I.EI..TD....CNQKNAFICE---------------------idinrpa........................................................................................
A0A452QIG9_URSAM/5-148                 ...........................................gvtyaelnivknskr-----QQRKAKGTKSSTSVTEQEITY.AELN------..-.--------...--Lqtasqdlqgng...............knshckgkliaeILGII.CLVLM...S...T.V......VTI.A.V..I..T....C..KFV................wI.I..SP...N.L...S...P......A..Y........H...CCPK.EWLAHSNNC.YYISTEKK...........-TWNESSMSC.AIKNS.N..L..L..S...--..-...-..-..-...-..----.....-...-.....-...-.....-.-..-..-..--.----...............................------.-----.----.-.-.--..--....-------------------------------ideed..........................................................................................
A0A0L0BR94_LUCCU/142-235               .......................................................nde--------------------------.----------..-.--------...---......................................-----.-----...-...-.-......---.-.-..-..-....-..---.................-.-..--...-.-...-...-......-..L........N...YCPE.HWISFRQEC.YRFIRSPK...........RNWIEAKKIC.KAYNA.E..L..L..N...VD..N...V..E..KhsfI..LKHL.....I...L.....Q...N.....H.R..Q..N..RF.WT--...............................------.-----.----.-.-.--..--....-------------------------------sarqtgvnswgnddgtpflmidd........................................................................
A0A3Q7S032_VULVU/15-172                ........................................................nn--SKRQQMKTKETKNSISVTEQEITY.TELNLQNASK..D.HPGERKNH...HYKdlllfp..........................gkilarMLGII.CFVLM...S...T.V......ITI.V.L..I..P....C..KXNns.............slK.T..NI...Q.K...A...Y......H..C........G...HCPK.EWFTYSNHC.YYISTERK...........-PWNESLASC.ASNNS.N..L..L..Y...ID..D...E..E..E...L..VD--.....-...-.....-...-.....-.-..-..-..--.----...............................------.-----.----.-.-.--..--....-------------------------------iyrvssclqwa....................................................................................
Q6VZ40_CNPV/2-153                      ...................................................eenkcnk--------------------------.----------..-.--------...---......................................--VTV.CWILVpcsS...I.I......IAL.S.I..L..V....I..IFS.................I.K..PP...P.H...D...L......S..K........F...SCPN.DWIGYNKKC.YYFSNTTD...........-NKYSASEKC.KDMNA.E..L..A..H...VK..D...V..N..E...L..NFML.....R...Y.....K...G.....L.D..D..Y..--.WVVIetndk....................fvsddvTGTKGS.NNCVF.LKDK.T.-.IS..SS...lCNVTKKWICS---------------------fvlpi..........................................................................................
A0A1X9T5H3_9VIRU/50-214                .....pdcqtrpptpcpydtypsrnmsirdriyfnwryakdfategyvatryliftfs--------------------------.----------..-.--------...---......................................-----.-----...-...V.M......L--.L.L..L..I....V..SLC.................V.A..IN...V.R...C...V......S..V........A...MCPK.GWMKDGDLC.FQVQDYMA...........-NYTEAVDLC.SREKA.E..L..M..N...HQ..T...-..-..H...F..AVVQ.....K...V.....C...E.....S.W..N..G..--.----...............................------.-----.----.-.-.--..--....-------------------------------lrynetqkkytfkdntaikypttftpiaksntlt.............................................................
A0A1U7T7L2_TARSY/7-157                 iyselnlppnqknqernsksnkssilvteqeityvelslqtvsqdlldndktflskdl--------------------------.---------S..S.------AP...EKL......................................IAGIL.GIICL...A...L.I......VTM.V.T..I..V....T..VLStetq........eqtnsFqN..ES...K.Q...K...A......Y..N........G...SCPE.EWFTYSNSC.YFIGKETK...........-TWDESMMTC.ASMNS.N..L..-..-...--..-...-..-..-...-..----.....-...-.....-...-.....-.-..-..-..--.----...............................------.-----.----.-.-.--..--....-------------------------------lyid...........................................................................................
B4QV10_DROSI/133-235                   .....................................................tdedn--------------------------.----------..-.--------...---......................................-----.-----...-...-.-......---.-.-..-..-....-..---.................-.-..--...-.-...-...-......-..-........-...FCPE.HWVSFRQTC.YRFIRSPK...........RNWAEAKKIC.KAYNA.D..L..I..N...VD..N...V..E..K...H..SFIL.....K...N.....L...I.....L.Q..N..Q..RQ.NRFFisarq....................tgplnwVNDDNT.-----.----.-.-.--..--....-------------------------------qlvqiedsfsmdeqvp...............................................................................
EV45_HHV2H/5-171                       .............................................asgpayqplapaa--------------------------.----------..-.------SP...ARA......................................RVPAV.AWIGV...G...A.I......VGA.F.A..L..V....A..ALV.................L.V..PP...R.S...S...W......G..L........S...PCDS.GWQEFNAGC.VAWDPTPV...........-EHEQAVGGC.SA-PA.T..L..I..P...RA..A...A..K..H...L..AALT.....R...V.....Q...A.....E.R..S..S..GY.WW--...............................VNGDGI.RTCLR.LVDS.V.S.GI..DE...fFEELAIRICYYPRSPGGFVRFVTSIRNALGL...............................................................................................
B4NID8_DROWI/163-263                   ....................................................fsdeen--------------------------.----------..-.--------...---......................................-----.-----...-...-.-......---.-.-..-..-....-..---.................-.-..--...-.-...-...-......-..-........-...FCPE.HWVSFRQTC.YRFIRSPK...........RNWAEAKKIC.KAYNA.D..L..I..N...VD..N...V..E..K...H..SFIL.....R...N.....L...I.....V.Q..N..Q..RQ.NRFFisarq....................tgpqnwVNDDNT.-----.----.-.-.--..--....-------------------------------qlihiedsfafde..................................................................................
EV45_PSHV1/50-296                      ......................................................eatd----DYKARRRNLESEPPFEVRAILD.DELSDYPVAAplD.AVPQKHSC...C-Cgvc................................lrrCAFVL.TGMAV...G...M.L......LAA.A.L..L..A....T..IAA.................F.A..VP...E.S...V...W......T..G........G...VCER.GWVQHMGVC.YKPGRTPPpssaadgnfsaATFAGANTNC.AAAGG.S..I..V..S...SD..Q...A..L..S...F..LVLL.....S...K.....T...A.....S.G..P..N..SA.PPRGswwtthsgscaiv....hyapsstlevygntSSLQSL.ALRTR.DALD.V.S.IA..EDt..qCSGSAGVMCAAAPAPPTALKYAQALRAILTL...............................................................................................
B4K8Y9_DROMO/162-259                   .....................................................tdedn--------------------------.----------..-.--------...---......................................-----.-----...-...-.-......---.-.-..-..-....-..---.................-.-..--...-.-...-...-......-..-........-...FCPE.HWISFRQTC.YRFIRSPK...........RNWAEAKKIC.KAYTA.D..L..V..N...VD..N...V..E..K...H..AFIL.....K...Q.....L...I.....I.Q..N..Q..RQ.NRFFisarq....................tgpqnwVNDDNT.Q----.----.-.-.--..--....-------------------------------liqiedsfaf.....................................................................................
A0A3Q0IPR7_DIACI/4-82                  ..............................................issclfifvsfh--------------------------.----------..-.--------...---......................................-----.-----...-...-.-......---.-.-..-..-....-..-SV.................F.S..QT...I.D...E...L......E..L........-...RCPQ.HWVQYRDSC.YRFVKSPL...........KTRNDAKLNC.KSLDS.D..L..A..N...VN..D...A..-..-...-..----.....-...-.....-...-.....-.-..-..-..--.----...............................------.-----.----.-.-.--..--....-------------------------------dehgfimyqlf....................................................................................
A0A1U7SQE5_TARSY/12-157                ..............nlppnlknqerkskgnkssilvteqeityaelslqtasqdllhn--------------------------.------DKTF..H.SKDLLSPP...VKL......................................IAGIL.GIICL...G...L.I......VTM.V.T..I..V....I..ILStakqk.......qtnsfQ.N..AS...T.Q...K...A......H..N........C...SCPE.EWFTYSNSC.YYIGKETK...........-TWEESMMAC.ASMNS.S..L..-..-...--..-...-..-..-...-..----.....-...-.....-...-.....-.-..-..-..--.----...............................------.-----.----.-.-.--..--....-------------------------------lyid...........................................................................................
#=GC seq_cons                          ........................................................tt........................................................................................................................hhh.h.h..l..........hhh.................h.s...s.........s...h......t..s........s...pCPp.cWlsasssC.Ythspssh............sap-ApphC.pshsu.p..L..h..s...hs..s...h.....t...h..h.hh.....t..................................................................................................................................................................................................................................
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