GenomeNet

Database: Pfam
Entry: Uso1_p115_C
LinkDB: Uso1_p115_C
Original site: Uso1_p115_C 
#=GF ID   Uso1_p115_C
#=GF AC   PF04871.15
#=GF DE   Uso1 / p115 like vesicle tethering protein, C terminal region
#=GF AU   Kerrison ND;0000-0002-1471-953X
#=GF SE   Pfam-B_6073 (release 7.6)
#=GF GA   28.40 28.40;
#=GF TC   28.40 28.40;
#=GF NC   28.30 28.30;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 57096847 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Family
#=GF RN   [1]
#=GF RM   11927603
#=GF RT   Sequential tethering of Golgins and catalysis of SNAREpin
#=GF RT   assembly by the vesicle-tethering protein p115. 
#=GF RA   Shorter J, Beard MB, Seemann J, Dirac-Svejstrup AB, Warren G; 
#=GF RL   J Cell Biol 2002;157:45-62.
#=GF RN   [2]
#=GF RM   12077354
#=GF RT   Vesicle tethering complexes in membrane traffic. 
#=GF RA   Whyte JR, Munro S; 
#=GF RL   J Cell Sci 2002;115:2627-2637.
#=GF DR   INTERPRO; IPR006955;
#=GF DR   SO; 0100021; polypeptide_conserved_region;
#=GF CC   Also known as General vesicular transport factor, Transcytosis
#=GF CC   associate protein (TAP) and Vesicle docking protein, this
#=GF CC   myosin-shaped molecule consists of an N-terminal globular head
#=GF CC   region, a coiled-coil tail which mediates dimerisation, and a
#=GF CC   short C-terminal acidic region [1].  p115  tethers COP1 vesicles
#=GF CC   to the Golgi by binding the coiled coil proteins giantin (on the
#=GF CC   vesicles) and GM130 (on the Golgi), via its C-terminal  acidic
#=GF CC   region.  It is required for intercisternal transport in the
#=GF CC   golgi stack. This family consists of the acidic C-terminus,
#=GF CC   which binds to the golgins giantin and GM130.  p115 is thought
#=GF CC   to juxtapose two membranes by binding giantin with one acidic
#=GF CC   region, and GM130 with another [2].
#=GF SQ   1413
#=GS A0A1S8BJK9_9PEZI/883-1045   AC A0A1S8BJK9.1
#=GS A0A151GG12_9HYPO/800-934    AC A0A151GG12.1
#=GS A0A091NJ74_APAVI/839-940    AC A0A091NJ74.1
#=GS A0A4U5U2K9_COLLU/826-947    AC A0A4U5U2K9.1
#=GS A0A2K3L476_TRIPR/54-147     AC A0A2K3L476.1
#=GS L8G7E9_PSED2/782-909        AC L8G7E9.1
#=GS V5EZL7_KALBG/1284-1409      AC V5EZL7.1
#=GS Q7ZW40_DANRE/826-956        AC Q7ZW40.1
#=GS A0A5B7GVA7_PORTR/1-175      AC A0A5B7GVA7.1
#=GS F2EL68_HORVV/798-929        AC F2EL68.1
#=GS A0A5J5DNE0_9PERO/125-229    AC A0A5J5DNE0.1
#=GS A0A151RN78_CAJCA/787-915    AC A0A151RN78.1
#=GS F0UA89_AJEC8/810-931        AC F0UA89.1
#=GS A0A1V6YR15_PENNA/1002-1143  AC A0A1V6YR15.1
#=GS M4DJL4_BRARP/24-152         AC M4DJL4.1
#=GS A0A226NET4_CALSU/712-841    AC A0A226NET4.1
#=GS A5DLM2_PICGU/1701-1839      AC A5DLM2.2
#=GS A0A0C3C829_HEBCY/715-835    AC A0A0C3C829.1
#=GS A0A5C6MUW8_9TELE/790-913    AC A0A5C6MUW8.1
#=GS A0A1R3HFX8_9ROSI/576-702    AC A0A1R3HFX8.1
#=GS A0A4W3J423_CALMI/830-960    AC A0A4W3J423.1
#=GS A0A3A2ZPC7_9EURO/929-1081   AC A0A3A2ZPC7.1
#=GS A0A2P4Z9R3_9HYPO/895-1037   AC A0A2P4Z9R3.1
#=GS A0A139AYD5_GONPJ/732-866    AC A0A139AYD5.1
#=GS A0A1B9I3A8_9TREE/958-1090   AC A0A1B9I3A8.1
#=GS A0A3Q3MIK2_9TELE/826-957    AC A0A3Q3MIK2.1
#=GS A0A672YRJ0_9TELE/790-921    AC A0A672YRJ0.1
#=GS A0A061ED20_THECC/490-616    AC A0A061ED20.1
#=GS B8M0U6_TALSN/840-985        AC B8M0U6.1
#=GS S8BJP5_DACHA/871-995        AC S8BJP5.1
#=GS A0A6G0J984_LARCR/855-976    AC A0A6G0J984.1
#=GS A0A455BFZ1_PHYMC/801-971    AC A0A455BFZ1.1
#=GS A0A2G5DXA4_AQUCA/797-925    AC A0A2G5DXA4.1
#=GS A0A5N6Z7M5_9EURO/952-1066   AC A0A5N6Z7M5.1
#=GS A0A672HN51_SALFA/828-958    AC A0A672HN51.1
#=GS A0A1B7MYU7_9AGAM/710-825    AC A0A1B7MYU7.1
#=GS J3PD62_GAET3/812-965        AC J3PD62.1
#=GS A0A044T642_ONCVO/718-884    AC A0A044T642.1
#=GS A0A166B073_EXIGL/737-874    AC A0A166B073.1
#=GS Q2UCP4_ASPOR/890-1056       AC Q2UCP4.1
#=GS J7R5P7_KAZNA/2065-2219      AC J7R5P7.1
#=GS A0A565BS76_9BRAS/787-915    AC A0A565BS76.1
#=GS A0A0S6XVQ8_9FUNG/945-1080   AC A0A0S6XVQ8.1
#=GS A0A1D5PRZ7_CHICK/784-963    AC A0A1D5PRZ7.2
#=GS A0A2S7Q9D8_9HELO/754-896    AC A0A2S7Q9D8.1
#=GS A0A063BX22_USTVR/817-940    AC A0A063BX22.1
#=GS A0A1F8AA63_9EURO/1068-1190  AC A0A1F8AA63.1
#=GS A0A2U3ZLP7_ODORO/815-966    AC A0A2U3ZLP7.1
#=GS A0A674HMM8_TAEGU/694-863    AC A0A674HMM8.1
#=GS A0A1W4WNJ3_AGRPL/690-815    AC A0A1W4WNJ3.1
#=GS F7EIK3_MACMU/722-892        AC F7EIK3.3
#=GS A0A0E0FNV8_ORYNI/782-912    AC A0A0E0FNV8.1
#=GS A0A2H3IG45_9EURO/845-984    AC A0A2H3IG45.1
#=GS A0A4C1X6S8_EUMVA/723-844    AC A0A4C1X6S8.1
#=GS A0A446ST89_TRITD/797-931    AC A0A446ST89.1
#=GS A0A397VA04_9GLOM/684-796    AC A0A397VA04.1
#=GS A0A2G8LQK6_STIJA/754-910    AC A0A2G8LQK6.1
#=GS A0A1J7IXT3_9PEZI/708-830    AC A0A1J7IXT3.1
#=GS H0YTJ2_TAEGU/737-905        AC H0YTJ2.2
#=GS W9CKK2_SCLBF/831-958        AC W9CKK2.1
#=GS A0A5C3MZK2_9AGAM/713-830    AC A0A5C3MZK2.1
#=GS M3AG35_PSEFD/1001-1134      AC M3AG35.1
#=GS A0A420HDA7_9PEZI/768-900    AC A0A420HDA7.1
#=GS G3SP88_LOXAF/766-941        AC G3SP88.1
#=GS F4PCC2_BATDJ/713-824        AC F4PCC2.1
#=GS A0A1B8EPT9_9PEZI/782-909    AC A0A1B8EPT9.1
#=GS A0A2K5JZ91_COLAP/780-954    AC A0A2K5JZ91.1
#=GS A6R8Q4_AJECN/814-931        AC A6R8Q4.1
#=GS Q1K4Z6_NEUCR/1036-1171      AC Q1K4Z6.1
#=GS A0A673WEJ2_SALTR/854-988    AC A0A673WEJ2.1
#=GS A0A0H2RD36_9AGAM/730-856    AC A0A0H2RD36.1
#=GS A0A383YRX1_BALAS/789-962    AC A0A383YRX1.1
#=GS G3YHM9_ASPNA/933-1053       AC G3YHM9.1
#=GS A0A485P7Z6_LYNPA/645-794    AC A0A485P7Z6.1
#=GS A0A3P9CUS5_9CICH/829-955    AC A0A3P9CUS5.1
#=GS A0A673WF92_SALTR/841-975    AC A0A673WF92.1
#=GS A0A0E9NME8_SAICN/1079-1238  AC A0A0E9NME8.1
#=GS A0A1V6PN00_PENDC/880-1021   AC A0A1V6PN00.1
#=GS A0A671G096_RHIFE/790-960    AC A0A671G096.1
#=GS A0A4W5NEX0_9TELE/831-966    AC A0A4W5NEX0.1
#=GS A0A1U8LGK2_GOSHI/715-840    AC A0A1U8LGK2.1
#=GS A0A671WR76_SPAAU/789-910    AC A0A671WR76.1
#=GS A0A421J6K6_9ASCO/1711-1854  AC A0A421J6K6.1
#=GS A0A094FBJ1_9PEZI/781-909    AC A0A094FBJ1.1
#=GS A0A2Y9QI90_DELLE/792-945    AC A0A2Y9QI90.1
#=GS G7DWQ0_MIXOS/777-897        AC G7DWQ0.1
#=GS A0A4Z1P9I9_9PEZI/780-962    AC A0A4Z1P9I9.1
#=GS H3E375_PRIPA/751-875        AC H3E375.2
#=GS A0A5M9JBB9_MONFR/720-847    AC A0A5M9JBB9.1
#=GS A0A1D6IWJ7_MAIZE/641-772    AC A0A1D6IWJ7.1
#=GS A0A2G4SRW1_RHIZD/657-830    AC A0A2G4SRW1.1
#=GS A0A2R6RQ65_9APHY/713-822    AC A0A2R6RQ65.1
#=GS A0A2B7X4M3_9EURO/814-932    AC A0A2B7X4M3.1
#=GS V7C0K5_PHAVU/787-916        AC V7C0K5.1
#=GS A0A2U3WD14_ODORO/789-959    AC A0A2U3WD14.1
#=GS I1IHT3_BRADI/798-933        AC I1IHT3.1
#=GS A0A3Q1JXX6_ANATE/827-958    AC A0A3Q1JXX6.1
#=GS A0A1S3DXX1_CICAR/786-913    AC A0A1S3DXX1.1
#=GS A0A5A7T816_CUCME/785-912    AC A0A5A7T816.1
#=GS M7TJT6_BOTF1/905-1044       AC M7TJT6.1
#=GS A0A672URD3_STRHB/826-937    AC A0A672URD3.1
#=GS E9CXP2_COCPS/802-929        AC E9CXP2.1
#=GS L8HRR4_9CETA/806-957        AC L8HRR4.1
#=GS A0A5M6C8F6_9TREE/959-1080   AC A0A5M6C8F6.1
#=GS A0A665XE41_ECHNA/917-1035   AC A0A665XE41.1
#=GS M0RTH7_MUSAM/565-691        AC M0RTH7.1
#=GS A0A091FNV0_9AVES/840-943    AC A0A091FNV0.1
#=GS G3I9F0_CRIGR/585-749        AC G3I9F0.1
#=GS A0A162BAF8_DAUCS/770-895    AC A0A162BAF8.1
#=GS A0A0Q3LY36_AMAAE/786-950    AC A0A0Q3LY36.1
#=GS A0A3P9CWB4_9CICH/821-925    AC A0A3P9CWB4.1
#=GS V9KCJ9_CALMI/844-967        AC V9KCJ9.1
#=GS A0A2V1BCE6_9HELO/772-909    AC A0A2V1BCE6.1
#=GS A0A072PK08_9EURO/840-968    AC A0A072PK08.1
#=GS A0A0C4EPV7_PUCT1/669-765    AC A0A0C4EPV7.1
#=GS A0A6I8T0B0_XENTR/784-862    AC A0A6I8T0B0.1
#=GS A0A1B8E4Q2_9PEZI/782-909    AC A0A1B8E4Q2.1
#=GS A0A6I8S1T7_XENTR/788-966    AC A0A6I8S1T7.1
#=GS A0A1V6RAD8_9EURO/1003-1145  AC A0A1V6RAD8.1
#=GS A0A0C7MKW0_9SACH/1579-1713  AC A0A0C7MKW0.1
#=GS A0A669CA01_ORENI/843-970    AC A0A669CA01.1
#=GS A0A1X2I3W2_9FUNG/652-775    AC A0A1X2I3W2.1
#=GS A0A287QPN3_HORVV/798-929    AC A0A287QPN3.1
#=GS A0A1V6V683_9EURO/1003-1146  AC A0A1V6V683.1
#=GS A0A074YUY9_AURSE/1022-1141  AC A0A074YUY9.1
#=GS A0A2K3MFH0_TRIPR/155-239    AC A0A2K3MFH0.1
#=GS A0A2I3RND8_PANTR/800-965    AC A0A2I3RND8.1
#=GS A0A3M9YG99_9PEZI/844-984    AC A0A3M9YG99.1
#=GS G1M7I8_AILME/788-938        AC G1M7I8.1
#=GS A0A1D6IWI6_MAIZE/811-942    AC A0A1D6IWI6.1
#=GS T5AC17_OPHSC/815-928        AC T5AC17.1
#=GS G3PZ97_GASAC/832-944        AC G3PZ97.1
#=GS A0A0D2K9S0_9EURO/830-965    AC A0A0D2K9S0.1
#=GS A0A1E3QMY1_9ASCO/1649-1762  AC A0A1E3QMY1.1
#=GS A0A3L6REE6_PANMI/771-901    AC A0A3L6REE6.1
#=GS A0A0C3HGF4_9PEZI/772-909    AC A0A0C3HGF4.1
#=GS A0A643BU90_BALPH/775-948    AC A0A643BU90.1
#=GS A0A060SNJ9_PYCCI/745-855    AC A0A060SNJ9.1
#=GS A0A2K6TMN5_SAIBB/785-954    AC A0A2K6TMN5.1
#=GS U7PJC0_SPOS1/70-223         AC U7PJC0.1
#=GS A0A662YZ86_ACIRT/5-101      AC A0A662YZ86.1
#=GS A0A287QPN4_HORVV/592-723    AC A0A287QPN4.1
#=GS A0A669AY05_ORENI/774-880    AC A0A669AY05.1
#=GS A0A5N6MMP6_9ASTR/821-943    AC A0A5N6MMP6.1
#=GS A0A3Q2E342_CYPVA/825-940    AC A0A3Q2E342.1
#=GS A0A444EN78_ENSVE/378-471    AC A0A444EN78.1
#=GS A0A1R1WZP6_9FUNG/805-954    AC A0A1R1WZP6.1
#=GS A0A3Q1IFW5_ANATE/845-976    AC A0A3Q1IFW5.1
#=GS A0A2S4W6I6_9BASI/748-869    AC A0A2S4W6I6.1
#=GS E5A9Y3_LEPMJ/898-1018       AC E5A9Y3.1
#=GS A0A671WUZ8_SPAAU/851-960    AC A0A671WUZ8.1
#=GS A0A553PE35_9TELE/781-911    AC A0A553PE35.1
#=GS A0A3P7V0U9_9BILA/589-747    AC A0A3P7V0U9.1
#=GS A0A0N1GXB7_9EURO/799-945    AC A0A0N1GXB7.1
#=GS A0A673WF32_SALTR/843-977    AC A0A673WF32.1
#=GS A0A3Q3CLD3_HAPBU/822-948    AC A0A3Q3CLD3.1
#=GS G4USW4_NEUT9/1029-1154      AC G4USW4.1
#=GS A0A182H2B9_AEDAL/689-848    AC A0A182H2B9.1
#=GS A0A673VIK7_SURSU/812-963    AC A0A673VIK7.1
#=GS A0A2H3CZU1_ARMGA/712-832    AC A0A2H3CZU1.1
#=GS A0A2I4D512_9TELE/810-936    AC A0A2I4D512.1
#=GS A0A0D0BYB7_9AGAR/715-829    AC A0A0D0BYB7.1
#=GS A0A2A9NWI1_9AGAR/728-836    AC A0A2A9NWI1.1
#=GS K5W4A0_PHACS/712-827        AC K5W4A0.1
#=GS A0A4X2KTS8_VOMUR/807-910    AC A0A4X2KTS8.1
#=GS A8PR65_MALGO/879-999        AC A8PR65.1
#=GS A0A1V2LDV0_CYBFA/1682-1814  AC A0A1V2LDV0.1
#=GS A0A1B8D8H7_9PEZI/782-909    AC A0A1B8D8H7.1
#=GS A0A059J8U4_TRIIM/819-940    AC A0A059J8U4.1
#=GS A0A3M0KQM4_HIRRU/820-942    AC A0A3M0KQM4.1
#=GS A0A2L2TNM2_9HYPO/890-1044   AC A0A2L2TNM2.1
#=GS A0A1Q3EGP2_LENED/537-662    AC A0A1Q3EGP2.1
#=GS A0A3P9MYS0_POERE/826-936    AC A0A3P9MYS0.1
#=GS K2SFS9_MACPH/904-1029       AC K2SFS9.1
#=GS A0A0F4GWK0_9PEZI/1089-1229  AC A0A0F4GWK0.1
#=GS B8N4R1_ASPFN/1092-1217      AC B8N4R1.1
#=GS Q17BY2_AEDAE/689-848        AC Q17BY2.1
#=GS A0A673WR16_SALTR/847-981    AC A0A673WR16.1
#=GS A0A093GR20_TYTAL/752-914    AC A0A093GR20.1
#=GS A0A3Q3FNJ4_9LABR/847-970    AC A0A3Q3FNJ4.1
#=GS A0A087X5G3_POEFO/779-889    AC A0A087X5G3.2
#=GS A0A3P9CVR7_9CICH/833-959    AC A0A3P9CVR7.1
#=GS A0A0C9XVZ1_9AGAR/706-826    AC A0A0C9XVZ1.1
#=GS A0A2A4ITS7_HELVI/15-135     AC A0A2A4ITS7.1
#=GS A0A0D2HI77_9EURO/833-975    AC A0A0D2HI77.1
#=GS A0A060YPZ1_ONCMY/517-650    AC A0A060YPZ1.1
#=GS A0A337S5Y6_FELCA/789-963    AC A0A337S5Y6.2
#=GS W4JP29_HETIT/721-835        AC W4JP29.1
#=GS A0A1D6DWM2_MAIZE/49-179     AC A0A1D6DWM2.1
#=GS G8BQF8_TETPH/2380-2536      AC G8BQF8.1
#=GS A4RYG2_OSTLU/363-504        AC A4RYG2.1
#=GS A0A6A4UXN9_AMPAM/732-879    AC A0A6A4UXN9.1
#=GS A0A4Y9YT99_9APHY/658-769    AC A0A4Y9YT99.1
#=GS A0A1J1I1P1_9DIPT/731-840    AC A0A1J1I1P1.1
#=GS Q757G8_ASHGO/1106-1292      AC Q757G8.1
#=GS F6WA29_CIOIN/1-105          AC F6WA29.2
#=GS A0A673VJV7_SURSU/722-873    AC A0A673VJV7.1
#=GS USO1_MOUSE/782-954          AC Q9Z1Z0.2
#=GS A0A3P8YGY8_ESOLU/788-909    AC A0A3P8YGY8.1
#=GS A0A402FRK7_9SAUR/540-675    AC A0A402FRK7.1
#=GS A0A0B0P8X2_GOSAR/781-896    AC A0A0B0P8X2.1
#=GS E9G932_DAPPU/719-893        AC E9G932.1
#=GS A0A166VHF6_9HYPO/791-925    AC A0A166VHF6.1
#=GS A0A010S3M7_9PEZI/867-1018   AC A0A010S3M7.1
#=GS Q2EEM5_CAEEL/730-875        AC Q2EEM5.1
#=GS A0A2K5M9S2_CERAT/784-954    AC A0A2K5M9S2.1
#=GS A0A3N4KXX1_9PEZI/1122-1245  AC A0A3N4KXX1.1
#=GS A0A3B5KBT1_TAKRU/833-958    AC A0A3B5KBT1.2
#=GS A0A6A3APY0_HIBSY/716-843    AC A0A6A3APY0.1
#=GS A0A4W6BXC7_LATCA/553-720    AC A0A4W6BXC7.1
#=GS A0A317SJ49_9PEZI/889-989    AC A0A317SJ49.1
#=GS A0A0D7A5X3_9AGAR/720-838    AC A0A0D7A5X3.1
#=GS A0A3Q1JXR9_ANATE/849-980    AC A0A3Q1JXR9.1
#=GS A0A5D2ZHK5_GOSMU/780-906    AC A0A5D2ZHK5.1
#=GS A0A397GUI6_9EURO/932-1033   AC A0A397GUI6.1
#=GS A0A453K2M7_AEGTS/746-877    AC A0A453K2M7.1
#=GS A0A4S3JY49_9EURO/954-1082   AC A0A4S3JY49.1
#=GS A0A3Q3MBU8_9TELE/848-979    AC A0A3Q3MBU8.1
#=GS A0A1V6PUU4_9EURO/1192-1335  AC A0A1V6PUU4.1
#=GS R7S9D0_TREMS/819-934        AC R7S9D0.1
#=GS W5JDT6_ANODA/688-855        AC W5JDT6.1
#=GS W2T390_NECAM/789-921        AC W2T390.1
#=GS A0A066X641_COLSU/844-973    AC A0A066X641.1
#=GS R7UG30_CAPTE/747-882        AC R7UG30.1
#=GS A0A4W3J6Y3_CALMI/607-719    AC A0A4W3J6Y3.1
#=GS A0A067EDQ6_CITSI/529-656    AC A0A067EDQ6.1
#=GS A0A1J7IMN7_LUPAN/793-925    AC A0A1J7IMN7.1
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T5AC17_OPHSC/815-928                   .............................................................................................................................vtqe-----RDDEIKT....LR.E.EHS..R.LL.A.D......H.A...S......M..R.K.R.G..E.ERSRK..........................................---LESQ.......L.KKVQ...ATT...TE..MER...................................................KVE.R.A.ES.K..R...L...E....A....T......KSQE.AA...........................................QSELDELLIVFGDLEDKLARY......K.......A..........RL..RE..LGEN.V...............SDR.ED....D.....S.....Q...D...-..---...---g..................................
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J3KB91_COCIM/806-933                   ...........................................................................................................................ekankd--------HIQD....LQ.T.AHE..E.YS.S.K......L.S...S......L..E.G.R.C..K.RAEER..........................................EEDDRER.......A.NKLE...ADL...EK..ARD...................................................DLK.R.F.KA.D..F...D...E....S....E......NARS.TA...........................................QSELEDLLIVFADLEAKRNED......K.......K..........RL..KA..LGQE.Vs............dvE--.-D....D.....E.....D...D...G..DDD...DDDedddnd.............................
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