GenomeNet

Database: Pfam
Entry: WD40_like
LinkDB: WD40_like
Original site: WD40_like 
#=GF ID   WD40_like
#=GF AC   PF17005.6
#=GF DE   WD40-like domain
#=GF AU   Coggill P;0000-0001-5731-1588
#=GF SE   c_1703 - Hirt RP, Nakjang S
#=GF GA   40.00 40.00;
#=GF TC   40.00 40.00;
#=GF NC   39.90 39.70;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 47079205 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Family
#=GF WK   WD40_repeat
#=GF RN   [1]
#=GF RM   24259309
#=GF RT   Reduction and expansion in microsporidian genome evolution: new
#=GF RT   insights from comparative genomics.
#=GF RA   Nakjang S, Williams TA, Heinz E, Watson AK, Foster PG, Sendra
#=GF RA   KM, Heaps SE, Hirt RP, Martin Embley T;
#=GF RL   Genome Biol Evol. 2013;5:2285-2303.
#=GF DR   INTERPRO; IPR031544;
#=GF DR   SO; 0100021; polypeptide_conserved_region;
#=GF CC   This is a family of proteins which have weak homology to the
#=GF CC   WD40 repeat family. Members are largely from microsporidia and
#=GF CC   related species.
#=GF SQ   43
#=GS A0A0B2UNI8_9MICR/3-301    AC A0A0B2UNI8.1
#=GS A0A195EHY2_9HYME/75-309   AC A0A195EHY2.1
#=GS A0A059F3Y3_9MICR/14-299   AC A0A059F3Y3.1
#=GS A0A3M7Q486_BRAPC/263-453  AC A0A3M7Q486.1
#=GS A0A0F9WQ95_9MICR/3-301    AC A0A0F9WQ95.1
#=GS A0A1R0GNH1_9FUNG/79-402   AC A0A1R0GNH1.1
#=GS L7JWR4_TRAHO/138-241      AC L7JWR4.1
#=GS A0A195FBV4_9HYME/75-423   AC A0A195FBV4.1
#=GS L2GY11_VAVCU/307-412      AC L2GY11.1
#=GS R0MG28_NOSB1/82-379       AC R0MG28.1
#=GS A0A3S2M9M1_CHISP/225-550  AC A0A3S2M9M1.1
#=GS H8Z9C0_NEMS1/1-158        AC H8Z9C0.1
#=GS B7XMY6_ENTBH/16-78        AC B7XMY6.1
#=GS K9Y0P2_STAC7/1267-1444    AC K9Y0P2.1
#=GS E2A3S1_CAMFO/74-198       AC E2A3S1.1
#=GS A0A437AN53_9MICR/11-294   AC A0A437AN53.1
#=GS B7XN87_ENTBH/16-154       AC B7XN87.1
#=GS S7W9E7_SPRLO/12-317       AC S7W9E7.1
#=GS A0A194QNA3_PAPMA/71-393   AC A0A194QNA3.1
#=GS A0A1W0E4L2_9MICR/6-302    AC A0A1W0E4L2.1
#=GS A0A2A4J622_HELVI/73-397   AC A0A2A4J622.1
#=GS B7XM57_ENTBH/16-92        AC B7XM57.1
#=GS A0A1R0GX25_9FUNG/79-402   AC A0A1R0GX25.1
#=GS L2GY11_VAVCU/161-275      AC L2GY11.1
#=GS A0A158NKA7_ATTCE/75-408   AC A0A158NKA7.1
#=GS F4W8K9_ACREC/1-319        AC F4W8K9.1
#=GS J9JRX6_ACYPI/234-491      AC J9JRX6.1
#=GS L2GJY6_VITCO/20-253       AC L2GJY6.1
#=GS I3EK78_NEMP3/9-336        AC I3EK78.1
#=GS C4VAG3_NOSCE/15-313       AC C4VAG3.1
#=GS A0A177ECB8_9MICR/13-345   AC A0A177ECB8.1
#=GS A0A194PZD0_PAPXU/69-392   AC A0A194PZD0.1
#=GS A0A2T9Z2S7_9FUNG/64-385   AC A0A2T9Z2S7.1
#=GS B7XI71_ENTBH/16-313       AC B7XI71.1
#=GS A0A151I1K2_9HYME/75-224   AC A0A151I1K2.1
#=GS A0A151ZJZ6_9MYCE/103-266  AC A0A151ZJZ6.1
#=GS B7XQH1_ENTBH/16-131       AC B7XQH1.1
#=GS J8ZY85_EDHAE/6-349        AC J8ZY85.1
#=GS Q8SRX6_ENCCU/3-301        AC Q8SRX6.1
#=GS L7JWR4_TRAHO/1-121        AC L7JWR4.1
#=GS A0CJP1_PARTE/211-525      AC A0CJP1.1
#=GS A0A151I7S4_9HYME/76-413   AC A0A151I7S4.1
#=GS A0A1Y1XMQ9_9FUNG/206-480  AC A0A1Y1XMQ9.1
A0A0B2UNI8_9MICR/3-301               ........d-EIYCIDFYA.S.TRILLYGGKNNKCIAMNVDTGD..V..V..A..VV.E.DFDDSVVFCKFL.DSE....KFI.V.GS.LD..GTI--SLMTFEG..........EIN.NVC.LNEDIA..R..M..K..I..IG.D..K..VVV.G..TEVGNIHV........FS.L.D.L.....C.....FQNV.CIGQH..SEIL..DM.CYE..................................................NG..KLYTLT.AD.SFV.M.F..DS.N.T..HQK..LTG..F..KIK...N.......GLC..LDKI..PESDVI.C.IGSE..NMV...VI....S........K..NMNILAKIEVEG...L..P.LCALYM..N....N....YFV..I..GGCFE.YILL..VNIP..MGM.RV.FKIPL.....GTI.EVWDIRGDG.LNQIVFST.SCGLVGHGDIRDEKSFKLFKTDLRSIFDLCFKDQV....VYAAGENGYNVI.............................................
A0A195EHY2_9HYME/75-309              .......ht--VFCCSLSK.N.GDLVATGGEDDKGYLWNANTGE..S..I..L.nTG.D.SHNDSVIFSDFN.YND....KYV.-.AT.ADmrGKIKLWRISDKT..........CVW.ETA.LMNDIN..W..I..K..WhpFS.D..I..LVT.G..GETGEVYM........LK.T.R.-.....K.....DDYK.IFAQG..SGIK..SE.TGIilpdgtfllkreqntnlnltgkraaigyengmihvidlksntlvsttppdQT..RLYGHS.SN.-II.A.L..DC.YmD..NNL..LIS..V..SVE...S.......QTI..LSTV..HNGKVI.C.VL--..---...--....-........-..------------...-..-.------..-....-....---..-..-----.----..----..---.--.-----.....---.---------.--------.-----------------------------------....------------qdlhrh.......................................
A0A059F3Y3_9MICR/14-299              ........l-EVYSVNISN.S.NKEVIFGGGSDNVSVICVESNE..E..I..F..-T.D.TYNESIFYANFT.AD-....GII.V.IV.YD..GTVVFYDINYHK..........-CK.EHF.FNEEVS..V..V..K..E..YK.G..R..YFI.G..FESGRLII........LE.R.Y.-.....E.....IIYD.YTLFS..SGIL..DI.LID..................................................EE..MFYLLN.NE.SLL.I.Y..SI.D.F..-IE..IKR..H..KLK...N.......GQL..FCMM..--NKLI.C.VIEE..SIL...SF....Y........T..IHKKIHEIQIQE...V..-.ECMLTM..N....N....YIV..L..GGNFN.YLML..IDCN..--Y.QI.KKINL.....PIE.GSTRIKF-S.NNLLFISS.SDDKFCYGDFN---KFKVVESEVGVIFDYALSKEY....YVLAGEKGIS--i............................................
A0A3M7Q486_BRAPC/263-453             ....qvttf------DTN-.N.DDLIASGSLDGSVVFI-NRSTT..Q..I..M..KR.F.EFSDSIVHVKF-.DDP....FVL.V.VS.SG..GNLSKIDLNTFS..........LEK.SVK.LTETVT..S..A..Q..L..IN.N..N..ILI.G..TETGFIRV........YQ.K.D.T.....L.....AKIRdYPKSD..NPID..VI.ANL..................................................NG..SLFASS.SG.NEL.KiWtsNY.S.L..FSG..PID..T..TSK...V.......MAI..FMIS..-NKNVV.T.IGQD..GLI...IV....W........-..------------...-..-.------..-....-....---..-..-----.----..----..---.--.-----.....---.---------.--------.-----------------------------------....------------adprydrl.....................................
A0A0F9WQ95_9MICR/3-301               .........SEIYSIDYSF.K.SSYFLYGGNDQQCTIFSTRSNT..I..V..S..II.E.GFSESVIFCKLL.SDN....LIL.V.CS.ID..GYILTTDLNNSF..........-TS.TTQ.INEEIS..C..V..H..T..TD.N..H..FYI.G..TYTGTIYKi......hYK.E.D.I.....N.....CQEV.LMGHG..TEIL..SI.ISD..................................................NN..IIYTLS.SL.YFI.K.Y..--.I.N..NNI..EYK..I..NLV...D.......GVS..FSII..PDTEIF.C.ICTS..SDI...LI....Y........K..KDILIKKISSEY...Q..P.ECVIYT..E....G....YFV..V..GGYCD.YLLL..INTN..MNM.VT.YKYSL.....VSS.GVNKLIS-K.SYKVYFST.TCGYVGSCDIRKDDTVEMYESKVGTVFDMCVNNDT....FYIGGLNGVDIL.............................................
A0A1R0GNH1_9FUNG/79-402              .........EPVYSVAINPvD.TNIVVSGGGDDTAYVWRRDTGE..L..V..Q..KL.D.KHSDSVTAVGFS.VDG...qYVA.S.GG.MD..GKIKVYKTNPIT.........pHFV.FED.GPDEVV..W..LdwH..P..VG.N..V..FAV.G..ANDGSVWM........YN.VpG.K.....K.....LMNV.FYGHN..EPVT..TG.RFTh...............................................sgKN..IISGSE.DG.SLI.I.W..NP.A.N..ASV..VHK..F..SSE...DkrfhqegITS..LDIN..-SDDSI.I.ISGS..TDStakVL....H........K..NGNILGSLQAHS...D.sV.ETVGIS..S....A....MSMaaT..GSVDG.SICV..WDINtlRLR.DT.FK---.....HED.AVTKLKFVN.NSPLITSTsVDCTVKVWDSRSGENVRTWKGHQDAILDFALVGD-....------------gktvvtasddgcclv..............................
L7JWR4_TRAHO/138-241                 ...shvydi----------.-.----------------------..-..-..-..--.-.------------.---....---.-.--.--..------------..........---.---.------..-..-..-..-..--.-..-..---.-..--------........--.-.-.-.....-.....----.-----..----..--.---..................................................--..------.--.---.-.-..--.-.-..---..---..-..---...-.......---..----..------.-.----..---...--....-........-..--------SSNA...-..T.ECIAKI..N....D....DLV..I..GGEY-.-LMV..M-VK..--G.RE.--HRT.....AVQ.HVNLLVV-S.NTIVVFAT.LDGQIGIGDYREE-QFSMCDGGVGLVYDMVLCGNV....VYVAGENGTN--ei...........................................
A0A195FBV4_9HYME/75-423              .......ht--VFCCSLSK.N.GDLAATGGEDDKGYLWNASTGE..S..I..L..NTdD.SHNDSVIFSDFN.YND....KYV.-.AT.ADmrGKIKLWRISDKT..........CVW.ETA.LMNDIN..W..I..K..WhpFS.D..I..LVT.G..VETGEVYM........LK.T.R.-.....K.....DDYK.IFAQG..SGIK..SE.TGIilpdgtflfkreqninlnlagkravigyengmihvidlksntlvsttppdQR..RLHGHS.SS.-II.A.L..DC.YmD..NNL..LIS..V..SVE...S.......QTI..LSTI..HNGKVI.C.VLQD..LRR...RG....N........N..NDHIEIAAFCKD...-..-.PTFPVA..A....S....ATV..T..SETYG.KIYI..WDIS..K--.QS.LRNEM....dQEG.GITKLVWTK.ASIFFTAG.LDGKLRCFDAKIGHCLRIFSGHKGALYDLCISSD-....------------ekkaitvsddg..................................
L2GY11_VAVCU/307-412                 .....cftn----------.-.----------------------..-..-..-..--.-.------------.---....---.-.--.--..------------..........---.---.------..-..-..-..-..--.-..-..---.-..--------........--.-.-.-.....-.....----.-----..----..--.---..................................................--..------.--.---.-.-..--.-.-..---..---..-..---...-.......---..----..------.-.----..---...--....-........-..----LYNINVKG...T..-.ECIAKI..N....D....GLV..I..GGEF-.-LVI..ISQG..---.KE.YRT--.....EIK.DVNLLM-VR.DSTVIFTT.LHDQIGVGDYRG-EHFTLYDTDVGLVYDMAIDGNV....VYVAGESGMDHI.............................................
R0MG28_NOSB1/82-379                  .........EEVYNINFSF.N.N--ISYGSNRHTCTLYSLENDC..P..V..S..LF.E.GFSDSVIYSKQL.EEN....LIL.V.CT.ID..GTI--SLLSHDQ..........IIQ.SEK.IEEDIT..F..A..E..V..IK.D..K..IYI.G..GSLGSIYV........FN.L.D.L.....S.....SQNV.YLGHG..SDIH..KI.SYS..................................................NS..TIYSLS.DT.QFI.A.F..DE.F.S..FQQ..KYK..K..NFK...E.......AKI..FESF.gENQEIF.C.IGKE..GEV...VI....L........K..NGFILHKFPVQG...I..P.ECILFA..Y....D....HFI..V..GGSFP.FLIL..INTK..LNW.RE.YKLNL.....KIE.GSTKIQKIN.DFKIAIST.MCGLVGIGDIRKDDSFEFKESGVGSVFDFQFINGK....FYVGGAFGFDVV.............................................
A0A3S2M9M1_CHISP/225-550             ...vfcgkl--------HP.E.GKLAVTGGEDDVAFVWSTETGE..V..V..M..KC.D.GHKDSVIFAEFS.FCG....AYLaT.AD.MS..GVIKVWQCNTDEksq...qpwpMV-.FEY.EADDLSlgL..W..H..F..GA.R..V..LIV.G..TDGGDIYV........FK.I.P.T.....G.....ETKV.LQGHN..IKIE..CA.KVFs...............................................dgKR..LAAGYE.DG.ALK.I.W..DL.K.T..GQIihHIP..S..NVH...Q.......MRItdLDTH..PENNLIaS.ISTD..GKV...VL....T........AsvSGKVVSQLDTDN...D..L.EVVNFS..QdpqlD....YFA..I..GTLNG.SVSI..WDCT..RQM.IR.YHCSKss.deNAT.GVTKMLWIK.DHLVT-AG.LDGSVTVYEGRSGKKLHVFTGHRSELLDISFNC--....------------kanillttsddgtar..............................
H8Z9C0_NEMS1/1-158                   .......mt----------.-.----------------------..-..-..-..--.-.---------EFV.SSD....KAV.A.VS.MD..GTVASIAIKKEHgg.....ytkEIK.TVD.VQMDIT..K..A..V..V..SK.D..KqrLYI.G..TADGLVEE........LP.N.S.IdeiggR.....AVKV.YAGHS..SEIQ..DI.LES..................................................DT..CLYTVS.SG.QII.V.F..NK.E.T..GSV..SAR..Y..NAE...-.......---..----..------.-.----..---...--....-........-..------------...-..-.------..-....-....---..-..-----.----..----..---.--.-----.....---.---------.--------.-----------------------------------....------------ldsdirvvqinstgkslgvgygngslvilsysp............
B7XMY6_ENTBH/16-78                   .........TPIYAVDV--.K.GNYILVGGKDENAAVYTVDNGD..L..I..T..IV.A.DLEESVMFCKML.DDHd..vLYL.V.--.--..------------..........---.---.------..-..-..-..-..--.-..-..---.-..--------........--.-.-.-.....-.....----.-----..----..--.---..................................................--..------.--.---.-.-..--.-.-..---..---..-..---...-.......---..----..------.-.----..---...--....-........-..------------...-..-.------..-....-....---..-..-----.----..----..---.--.-----.....---.---------.--------.-----------------------------------....------------spmmt........................................
K9Y0P2_STAC7/1267-1444               ......wvn----TIDFAS.D.N-LLASGGEDNQIKLWEINNQT..SkeI..R..TI.T.GNQDRVTQVKFSaDGN....ELI.S.AS.GD..GEVKLWQVKDGK..........QIN.YFS.HQEQVN..S..V..A..F..TP.D..N..QLI.AtaTADGRINI........WN.K.D.G.....I.....LQQV.LVGHR..GEIT..DL.NFS..................................................--..------.--.---.-.-..--.-.-..---..---..-..---...-.......---..----..------.-.----..---...--....-........-..------------...-..-.------..-....-....---..-..-----.----..----..---.--.-----.....---.---------.--------.-----------------------------------....------------pieingnknqtqsyllasasvdktvkiwqinnlsaseaggiysva
E2A3S1_CAMFO/74-198                  .......hs--VFCCSLSK.N.SELAATGSEEDKAYVWNIITGE..I..I..L..EC.T.GHKDSVIFSGFN.YND....MYL.A.TGdMG..GIVKLWQISNKV..........CVW.ETA.L-DDIT..W..I..KwhT..SA.N..I..LLV.G..LETGEVHM........FK.L.-.-.....-.....----.-----..----..--.---..................................................--..------.--.---.-.-..--.-.-..---..---..-..---...-.......---..----..------.-.----..---...--....-........-..------------...-..-.------..-....-....---..-..-----.----..----..---.--.-----.....---.---------.--------.-----------------------------------....------------pegackvfaqgygd...............................
A0A437AN53_9MICR/11-294              ........l-EVYSINISK.D.NKEIIFGGANDTLSVLHIESNE..E..L..-..FT.D.EFNESIFYVNYF.E-D....LIL.A.VT.YT..GEV--FFYKDYT..........RTL.NYN.FSEEVS..L..V..K..I..ID.K..S..ICI.G..FESGRFLI........IK.D.N.-.....E.....VIFD.YFVSN..TNVL..DV.II-..................................................DN..FIYLLT.KN.LLL.I.Y..DC.N.F..-QE..IKR..F..SLT...E.......SVS..FTLF..--DNIL.A.VVEK..NFV...SF....F........N..LTKKVNEIYFTE...V..-.ECVVKL..N....N....FLV..L..GGNFD.YLLV..IDKN..--Y.SV.RKISL.....QVK.GVTRLKV-K.NQKLFFTS.SDDKFCYGDFY---NLCVYASSVGSVFDFDVCDEF....FVLGGEKGV---ii...........................................
B7XN87_ENTBH/16-154                  .........TPIYAVDV--.K.GNYILVGGKDENAAVYTVDNGD..L..I..T..IV.A.DLEESVMFCKML.DDHd..vLYL.V.VT.ND..GLI--CLMKLDQ..........SVE.ITK.RNEAIT..T..C..K..Y..TG.G..E..LLI.G..TETGQIHV........LS.K.E.-.....L.....LVTT.TLSWN..TPIK..EV.EKI..................................................NN..YIFGLV.EM.HL-.-.-..--.-.-..---..---..-..---...-.......---..----..------.-.----..---...--....-........-..------------...-..-.------..-....-....---..-..-----.----..----..---.--.-----.....---.---------.--------.-----------------------------------....------------.............................................
S7W9E7_SPRLO/12-317                  .........TEIYSLDINK.D.STYIIYGGKDDKCRILDFNTLE..E..K..Y..II.D.IFKDSIQHVNFL.DND....HFI.V.VT.LD..GAFMEYKIINENl........qVIR.EEK.IKNDVS..T..V..C..N..LD.K..K..IAI.G..TNVGEIYY........YN.N.D.-.....-.....FEMV.FSNHS..SEIL..EL.KIH..................................................EN..FLFSLS.VD.ALI.V.Y..NL.D.S..FSL..HRR..I..GIR...N.......IEN..FHIT..NFQNIF.L.LSFN..DHI...KI....L........K..RNEILQRIDMKG...K..P.LCFLNS..D....D....LVF..V..GCDTK.YICL..LNFK..ANV.NT.FYIDCvdgeeDIE.GITHIKIIN.SFFIVFST.LCGKIGFGDFRDKNTFLYQKCCEGVILSFEIRDNI....IFWYGESGFGVL.............................................
A0A194QNA3_PAPMA/71-393              .......gs--VFCCNLHP.D.GKFAVTGGEDDKAYVWSTETGQ..I..I..T..EC.A.GHKDSVIFVGFS.FDG....AFL.AsVD.MS..GVIKVWKCNFEStq......ewPVAfEYE.AGDLIW..G..L..W..H..FG.A..R..VLIcG..AASGDIFV........FK.I.P.S.....G.....DTKI.LPGHNvkTECG..KL.FSD..................................................GV..RLVSGY.ED.GTVkV.W..DL.K.T..NSV..LHQvpQ..NVH...Q.......IRV..TDVDthPENNVM.AsISTD..GKA...VL....T........TsvNGKVVAQLETDN...D..L.EAVAFS..Np.qlG....YLA..L..GTLNG.SVTI..WDAG..RQM.IR.HYCSKke.dgVAA.GVTKIFWIN.DQLVT-GC.LDGSIRIYDGRSGERSLMLTGHWLEIFDICYNEK-....------------qnillstsddgt.................................
A0A1W0E4L2_9MICR/6-302               ........g-EFYSVDI--.G.NTYFLVGGCNDEAVLYKKEGEA..I..K..T..IV.D.NLEESVMYVKIL.QETekecLFM.L.AT.VG..GLA--CLMTNNK..........AIE.IVD.LKENIS..F..C..T..F..IN.N..V..FYI.G..TEIGNVYV........YS.H.D.F.....E.....HLN-.TMSAN..VTVI..DI.QIN..................................................NT..SVGVLC.EN.KIC.I.G..DS.Y.G..-NV..IFE..K..YIP...D.......ISS..FVFL..-NGNVF.A.FTAG..RNF...AI....Y........K..EHNKLFETTFEE...E..A.DSVVLV..D....D....SFV..I..GGSFD.GIYC..VNIN..-NY.SI.YKIDI.....GIN.MIKDIKVIG.KYLVSFIQ.GENKIGVLDIRDKSSLRLYESMAEFIFSYGILGNE....IVIGGIKGYEY-i............................................
A0A2A4J622_HELVI/73-397              .......gs--VFCCDLHP.E.GKLAVTGGEDDRAYVWSVENGQ..L..V..M..DC.T.GHKDSVIFAGFS.FDG....AYL.AtAD.MS..GLIKVWKCNLEEnqq....tpwTVA.FEY.EADDLT..WglW..H..F..GA.R..V..LIF.G..TESGDIYV........FK.V.P.S.....G.....DTKV.LQGHN..TKVEcgKL.FHD..................................................GV..RLAAGY.ED.GVVkI.W..DL.K.T..SAV..LHQlpA..SVH...Q.......IRItaIDTH..PDDNLM.AsISTD..GKV...VL....T........TpnNGKVVGQLETEN...D..L.ETVAFA..Q....DtqlgFLA..T..GTLTG.AVGI..WDVA..RQM.IR.HQCAKs..ddAVG.GVTKMVWVK.-NHLVTGC.LDGSVRVYEGRTGERTQMLTGHRSEVLDLCFNPK-....------------qslilttsddgt.................................
B7XM57_ENTBH/16-92                   .........TPIYAVDV--.K.GNYILVGGKDENAAVYTVDNGD..L..I..T..IV.A.DLEESVMFCKML.DDHd..vLYL.V.VT.ND..GLI--CPMKLDQ..........SVG.N--.------..-..-..-..-..--.-..-..---.-..--------........--.-.-.-.....-.....----.-----..----..--.---..................................................--..------.--.---.-.-..--.-.-..---..---..-..---...-.......---..----..------.-.----..---...--....-........-..------------...-..-.------..-....-....---..-..-----.----..----..---.--.-----.....---.---------.--------.-----------------------------------....------------t............................................
A0A1R0GX25_9FUNG/79-402              .........EPVYSVAINPvD.TNIVVSGGGDDTAYVWRRDTGE..L..V..Q..KL.D.KHSDSVTAVGFS.VDG...qYVA.S.GG.MD..GKIKVYKTNPIT.........pHFV.FED.GPDEVV..W..LdwH..P..VG.N..V..FAV.G..ANDGSVWM........YN.VpG.K.....K.....LMNV.FYGHN..EPVT..TG.RFTh...............................................sgKN..IISGSE.DG.SLI.I.W..NP.A.N..ASV..VHK..F..SSE...DkrfhqegITS..LDIN..-SDDSI.I.ISGS..TDStakVL....H........K..NGNILGSLQAHS...D.sV.ETVGIS..S....A....MSMaaT..GSVDG.SICV..WDINtlRLR.DT.FK---.....HED.AVTKLKFVN.NSPLITSTsVDCTVKVWDSRSGENVRTWKGHQDAILDFALVGD-....------------gktvvtasddgcclv..............................
L2GY11_VAVCU/161-275                 .ryllikka----------.-.----------------------..-..-..-..--.-.------------.---....---.-.--.--..------------..........---.HQN.IRKDIT..S..V..T..H..HG.N..I..LLL.G..CEDGCIHV........FY.K.N.L.....Q.....CHTN.LEGHK..TEIN..GL.SIL..................................................NN..YIFSSS.AG.NFI.V.Y..KN.N.F..--V..VY-..-..---...-.......---..----..------.-.----..---...--....-........-..------------...-..-.------..-....-....---..-..-----.----..----..---.--.-----.....---.---------.--------.-----------------------------------....------------nhktdllkgmhmidgraylvyeegisvlkyne.............
A0A158NKA7_ATTCE/75-408              .......ht--VFCCSLSK.N.GNLVATGGEDDKGYLWNANTGE..G..I.lS..TG.D.SHNDSVIFSDFN.YND....KYV.-.AT.ADmrGKIKLWRISDKT..........CVW.ETA.LMNDIN..W..I..K..WhpFS.D..I..LVT.G..VETGEIYM........LK.T.R.-.....K.....DDCK.IFAQG..SGIK..SE.AGIilpdgkravigyengmi................hvidlksntlvsntppdQT..RLYGHS.SS.-II.A.L..DCyI.D..NNL..LIS..V..SVE...S.......QTI..LSTV..HNGKVI.C.ILQD..LHK...RG....N........N..NDHVEVAAFCKD...-..P.-TFPVA..A....S....ATV..T..SETYG.KIYI..WDIS..KQS.LR.HEMD-.....QEG.GVTKLVWIK.ASIFFTSG.LDGKLRCFDARIGHCLRIFSGHKGALYDVCISSD-....------------ekkaitvsddgt.................................
F4W8K9_ACREC/1-319                   ........m----------.-.----ATGGEDDKGYLWNTNTGE..G..I..L..STdD.SHNDSVIFSDFN.YND....KYV.V.TAdMR..GKIKLWRISDKT..........CVW.ETA.LMNDIN..W..I..K..WhpFS.D..I..LVT.G..VETGEVYM........LK.T.R.-.....T.....DDCK.IFAQG..SGIK..SE.AGIilpdgkraaigyengmi................hvidlksntlvsttppdQT..RLHGHS.SN.-II.A.L..DC.YmD..NNL..LIS..V..SVE...S.......QTI..LSTV..HNGKVI.C.VLQD..LHR...RG....N........N..NDHVEIAAFCKD...-..P.TFPAAA..S....-....ATV..T..SETYG.KIYI..WDIF..KQS.LR.HEMD-.....QEG.GVTKLVWTK.ASIFFTSG.LDGKLRCFDARIGHCLRIFSGHKGALYDVCISSD-....------------ekkamtvsddg..................................
J9JRX6_ACYPI/234-491                 .......gg--VYGVAWSA.D.STRLLTSSGDKTCKLWDVETKS..V..V..SefVIgN.QVED-QQVSCLW.QGN....YLL.T.VS.LN..GFITYLDVNNPE.........kPIR.IIKgHNKPIT..V..L..A..L..SP.DrsT..IYT.G..SHDGNITN........WN.A.A.N....gE.....NDRVkGVGHG..NQIN..GM.KLD..................................................ND..YLYTCGiDD.SLR.Q.V..DV.K.S..-NS..YTD..L..QVK...L.......NAQ..PRGM.dFNSNVI.V.TVTI..KEI...IV....L........K..NEKKVFNLPVDY...E..P.SAVAISpgA....G....YVA..V..GGALD.NKVH..-VYK..INE.ST.YNLEF.....VAE.---------.--------.-----------------------------------....------------cdhlgpitdcs..................................
L2GJY6_VITCO/20-253                  ........d-ELYTVDICP.S.KKHVIFGGKSETAEVYSYEEER..A..I..T..RI.E.EFSDSVIYAKFV.SEN....RFV.I.VT.TD..GTI--ALMEHSG..........DVC.IVD.LEEDIS..V..A..K..F..-S.E..K..LVV.G..ASSGRVYL........YD.A.C.L.....E.....HINT.LGGHS..SEII..SV.DYK..................................................EG..RILSMC.AN.YLI.A.H..DE.Q.G..-RV..LYT..L..KAS...E.......AYA..FKYI..-TSDVI.C.FARD..GKI...QI....F........K..QTRKLFEHNIEE...R..V.EDVEIV..G....K....SLA..V..GGEFD.YILL..IDTT..GHY.AT.FKLDV.....KTE.---------.--------.-----------------------------------....------------lt...........................................
I3EK78_NEMP3/9-336                   .........EEVYCIDTCK.E.TNMVISGGGDDAVTFHVFNGES..Y..VidE..VI.E.GFEDSVIMTEFI.SSD....KAI.A.VA.MD..GTIAEINLIKENgr.....ytkDVN.IVC.LQMDIT..K..AvlS..K..DK.K..R..IYI.G..TADGLVEE........FP.A.D.I.....AaiearAVRI.YAGHS..SEIQ..DI.LES..................................................DS..FLYTVS.GT.HII.I.F..SK.G.TgsVSA..RYK..A..EFE..tD.......IRA..VQIN..KTGKTV.A.VGYG..NGT...LV....LlsyspeqgK..LTNVYQNTQTER..eS..V.ESLAFF..E....D....TLI..Y..GDFSS.TVSI..LNIK..YKTeRV.CKLSE.....DKE.CVVKIITVS.EAVAMAIT.NAGKVCVFSLKMDNTMI------------------....------------ceyalssitlnavvfnrficaatvegiefl...............
C4VAG3_NOSCE/15-313                  .........SEIYSIDYSF.K.SSYFLYGGNDQQCTIFSTRSNT..I..V..S..II.E.GFSESVIFCKLL.SDN....LIL.V.CS.ID..GYILTTDLNNSF..........-TS.TTQ.INEEIS..C..V..H..T..TD.N..H..FYI.G..TYTGTIYKi......hYK.E.D.I.....N.....CQEV.LMGHG..TEIL..SI.ISD..................................................NN..IIYTLS.SL.YFI.K.Y..--.I.N..NNI..EYK..I..NLV...D.......GVS..FSII..PDTEIF.C.ICTS..SDI...LI....Y........K..KDIIIKKISSEY...Q..P.ECVIYT..E....G....YFV..V..GGYCD.YLLL..INTN..MNM.VT.YKYSL.....VSS.GVNKLIS-K.SYKVYFST.TCGYVGSCDIRKDDTVEMYESKVGTVFDMCVNNDT....FYIGGLNGVDIL.............................................
A0A177ECB8_9MICR/13-345              .........EEVYAMGYTG.L.LNMIISGGGDDAITLHVRDGLDyqI..G..E..VI.E.GLDDSVIFATFV.RGM....NPV.A.VT.MD..GTVVYLDIDSPEtlkcvehfeeNIH.PVS.LNLDVS..T..A..AlsS..CE.S..W..LYI.G..TTDGAITRvsaslpppYT.Q.D.-.....-.....THAV.YMGHP..SDVL..VI.EAV..................................................NE..VIYTAS.HT.QVI.L.F..CA.E.T..GAT..LKK..Y..LSQeegE.......IRT..MKVH..PTGKVV.A.LGYS..TGA...VV....Llsn..sqtT..NQGLLTVYRAEM...SlpV.ESLAFV..E....D....KLL..Y..GGFDS.VLKV..VDLK..YKT.ETeCAFKE.....DAS.CIVKIIPLN.ASIAIAAI.TNGKVFIVDIRTNNKILKEFSIPCTITDIMLCGNL....LCAATSEGVEV-i............................................
A0A194PZD0_PAPXU/69-392              .......gs--VFCCNLHP.D.GKFAVTGGEDDKAYVWSTETGE..I..V..T..EC.T.GHKDSVIFVGFS.FDG....AFL.AsVD.MS..GVIKVWKCNFEStq......ewPVAfEYE.AGDLIW..G..L..W..H..FG.T..R..VLIcG..AVSGDIFV........FK.I.P.S.....G.....DTKI.LPGHNvkTECG..KL.FSD..................................................GV..RLVSGY.ED.GTVkV.W..DL.K.T..NSV..LHQ..VppNVH...H.......MRVtdVDTH..PENNIM.AsISTD..GKA...VL....T........TsmNGKVVAQLETDD...D..L.ETVAFS..Np.qlG....FLA..L..GTLNG.SVSI..WDAG..RQM.MR.HYCSKke.dgVSA.GVTKIFWIN.DQLVT-GC.LDGSIRIYDGRSGERILMLTGHWLEIFDMCYNEKQ....------------nillstsddgta.................................
A0A2T9Z2S7_9FUNG/64-385              .........EPVYSVAINP.KdENMIVSGGGDDSAYIWRRDNGE..A..V..Y..KL.K.KHEDSVTSVGFS.NDG....KFL.AtGG.MD..GIINVYKSGIEE..........IYC.QLD.GPDEVM..W..MnwH..P..TG.N..V..FIA.G..SNDTTIWM........YN.A.S.S....kA.....CMNV.FHGHS..GPVS..CG.QFT..................................................NNgkNIVSGS.EDgSLI.L.W..NP.A.S..ASV..IQK..F..TPE...DkrfhqdaITS..ISVN..KDDTIF.V.TGSVdgTGK...LV....H........K..NGSILGSLEGHT..dS..V.ETVGIS..D....S....LAL..AatGSVDG.SLCVwdINTL..RLR.NT.FKH--.....-DD.AVTKLKWHNnSPLITSSS.ADCTIKVWDSRSGECVRVWKGHQDTILDFALSNDG....------------ntvvtasddgccl................................
B7XI71_ENTBH/16-313                  .........TPIYAVDV--.K.GNYILVGGKDENAAVYTVDNGD..L..I..T..IV.A.DLEESVMFCKML.DDHd..vLYL.V.VT.ND..GLI--CLMKLDQ..........SVE.ITK.RNEAIT..T..C..K..Y..TG.G..E..LLI.G..TETGQIHV........LS.K.E.-.....L.....LVTT.TLSWN..TPIK..EV.EKI..................................................NN..YIFGLV.EN.ALI.V.G..DV.Y.G..-NI..ETV..Y..DVH...G.......IQC..FQCI..-NKNII.A.IGTN..TKF...LI....Y........C..GKKLLFELDTEA...V..-.ETIAIW..K....H....ICI..L..GGGFN.GLKI..INMN..-NY.SH.YTILM.....ENI.YVRMIKYVC.EFVVIYIT.YDNFVGVMDIRDKMTLRLLDPELGDIYDIAYELNMqiinIVVGGEYGYKHF.............................................
A0A151I1K2_9HYME/75-224              .......ht--VFCCSLSK.N.GNLVATGGEDDKGYLWNANTGE..G..I..L..STdD.SHNDSVIFSDFN.YND....KYV.-.AT.ADmrGKIKLWRISDKI..........CVW.ETA.LMNDIN..W..I..K..WhpFS.D..I..LVT.G..VETGEIYM........LK.T.R.-.....K.....DDCK.IFAQG..SGIK..--.---..................................................--..------.--.---.-.-..--.-.-..---..---..-..---...-.......---..----..------.-.----..---...--....-........-..------------...-..-.------..-....-....---..-..-----.----..----..---.--.-----.....---.---------.--------.-----------------------------------....------------seagiilpddfcsrenvicilq.......................
A0A151ZJZ6_9MYCE/103-266             dpinslisk----------.-.DFMVFTGDDEGTIKVWDMRQQN..I..V..C..EF.Q.EHGDYISDIITL.DDK....HFV.S.TS.GD..GGLSIYNFVRHSm........eDIS.EKS.DNELLS..V..I..A..M..DNeK..K..LVC.G..SQEGQIYI........FDrN.N.L.....E.....KPQK.FVGHP..ESVD..SLvKIN..................................................EQ..TLFTGS.ED.GMI.R.Y..--.-.-..---..---..-..---...-.......---..----..------.-.----..---...--....-........-..------------...-..-.------..-....-....---..-..-----.----..----..---.--.-----.....---.---------.--------.-----------------------------------....------------vgikpkkllgvvgehs.............................
B7XQH1_ENTBH/16-131                  .........TPIYAVDV--.K.GNYILVGGKDENAAVYTVDNGD..L..I..T..IV.A.DLEESVMFCKML.DDHd..vLYL.V.VT.ND..GLI--CLMKLDQ..........SVE.ITK.RNEAIT..T..C..K..Y..TG.G..E..LLI.G..TETGQIHV........LS.K.E.L.....L.....VTTT.-----..----..--.---..................................................--..------.--.---.-.-..--.-.-..---..---..-..---...-.......---..----..------.-.----..---...--....-........-..------------...-..-.------..-....-....---..-..-----.----..----..---.--.-----.....---.---------.--------.-----------------------------------....------------ls...........................................
J8ZY85_EDHAE/6-349                   .........EELYSIDISK.N.GQLIAFGGKSDTLTLAKFPSLI..S..I..T..SE.T.SFTDSIIYVKFI.LND....VIL.C.AT.LD..GNLSLHVLENGEl........vEVD.NRD.LEEDIS..F..I..D..V..IN.D..L..VVV.G..TNKGSIHI........FS.Q.D.L.....Q.....NEIL.FVGQH..SEIR..DI.KIIfdesfinnnencdnnilqae.........nainekkivetdeneyfgsnfKG..KLYSLS.ES.HYM.I.F..DL.F.T..QGT..LYK..R..SYK...D.......FRT..FNIV..-NKDLL.F.IGNE..GES...LL....I........K..DNVVLQKYLFGS...-..-.ECTALV..D....D....YLV..S..GGSGF.SLTI..INIK..SPS.NC.FNLRFl..aeNVE.GISKIVRLS.KNIVGIAT.FCGKIAIGDVRSGETFKFYDCGVGIIYDMKFFRNY....VAVCGNAGLRIV.............................................
Q8SRX6_ENCCU/3-301                   .........SEVYTVDLNP.R.GSMVAYGGGNDRCTVMDLETGD..V..V..S..IV.E.NFGDSVIFCKFI.DGE....KLL.V.GS.LD..GTI--SLMTLEE..........EIN.NVS.VNEDIS..K..I..K..V..DK.D..K..LLV.G..TTRGNVHL........FS.L.D.L.....C.....IQNV.CIGQY..SEIQ..DM.CYE..................................................SG..RAYTLS.ET.NFM.V.F..DA.E.S..HRK..LMD..L..HVR...G.......GSA..IGKM..PSSDVV.C.LGLE..GCI...VV....R........K..NAHLLGRIEVDG...S..P.ECILYM..N....N....YFI..V..GGDFD.YILL..INMP..MSM.RT.FKIPV.....GVE.GISGIRGDG.ENRIAFST.CNGAVGYGDIRDEKSFKLIEGGVGCIFDMCFKGDT....IYVGGEHGFNAL.............................................
L7JWR4_TRAHO/1-121                   .....vker----------.-.----------------------..-..-..-..--.-.------------.---....---.-.--.--..------------..........---.-RC.LHKDIS..F..V..T..H..HK.N..I..LLI.G..CTDGEIHL........FY.K.N.L.....Q.....HHIN.LAGHK..SEIT..AL.SIL..................................................NN..YVFSCS.AQ.NFI.V.Y..--.K.N..NSV..VHN..H..KTN...E.......LKG..MRVI..--DDRI.Y.LMYN..HCI...RV....L........K..HDA---------...-..-.------..-....-....---..-..-----.----..----..---.--.-----.....---.---------.--------.-----------------------------------....------------cfstsynekey..................................
A0CJP1_PARTE/211-525                 ...qnpvsk----------.-.-DLIASGSEDDHLKIIKLSTQK..V..I..-..FE.K.KYDETVGLVDFN.YDG....KYL.A.AGiLT..GKIYIYLLNDMSe........kMLD.GSQ.TEPSVL..K..W..H..P..KG.N..V..ILA.G..FQDSTLWM........WN.G.V.T....gE.....VMSV.FAGHE..AEIT..--.--Cggftldgk.................................livsgsadqSF..RVWKPS.TS.E-Q.V.Y..KI.S.S..VSH..KHN..Y..HKD...D.......VVC..FVQH..YKQPII.A.TGSS..DST...IAf.inF........E..DGKVIGKSDPLGdsiV..E.LCFIGT..N....Q....PII..V..AGDMSgSVYI..YNWN..SMK.LI.EKLCL.....CKN.SITKILFYN.-QQFHISS.LDGKIVTFDVRQMHNYRVLQAKSG-IYEMIVEEGW....ILVGCENGFV--yv...........................................
A0A151I7S4_9HYME/76-413              ......hiv---FCCSLSK.N.GDLMATGGEDDKGYLWNTNTGE..S..I..F..NT.DgSHDDSVIFAEFN.YND....KYL.AtAD.MC..GKIKLWRISDKT..........CVW.ETV.LMNDIN..W..I..K..WhpFS.D..I..LIT.G..TETGEVYM........LK.T.R.-.....K.....DDCK.IFAQG..TGIK..TE.AGVilpdgkraaigyengmi................hvidlksntlisttppdQT..GLHGHS.ST.-II.A.L..DC.YmD..NNL..LIS..V..SME...S.......QTI..LSTA..HNGKVI.C.ILQD..LNK...HG....D........N..KDHV-EVVAFCK...D..P.TFPAAA..S....A....TVT..S.eTCGKI.YIWD..ISKQ..IPF.QN.LRHEI.....NQEgGVSKLVWTK.TSIFFTAG.LDCKLRCFDARAGHYLRVFSGHRGALYDICISSD-....------------ekkavtvsddgt.................................
A0A1Y1XMQ9_9FUNG/206-480             .....nnkk----------.-.---------------------Y..S..I..Y..NM.V.SHTDSI-YCLQY.NNE....RII.S.GS.RD..QTIKVWDLKTNE..........CIK.TLNgHTGSIL..S..L..Q..F..DA.N..Y..LVT.G..SSDSTIIL........WD.I.KsF.....E.....IVRR.ITGHQ..DSVL..SV.KFN..................................................KD..YIVSSS.KD.HTIrI.W..DI.K.T..GEF..VRK..L..EGH...K.......TVA..NAIQ..-LKGDI.I.VSAS..GDR...LIrawsL........S..TGKLLKTFEGHT...R..GiACIFFD..G....N....III..S..GSSDC.TLKV..WDFH..SNK.LL.FTLYG.....HTE.LVRTIQFDG.K-KIVSGS.YDRTIKIWDFKSKQLLFSLDGHLSKIFCLQFSDSK....IISC--------ssdkh........................................
#=GC seq_cons                        ...........lashshp..p.sphlhsGGpD-pshlashpssp..h..l..h..hh.s.sapDSVhaspF...ss....hhl.s.ss.hD..GhI..hths.pp..........tlt.thp.htc-Is..h..h..p..h..hs.s..h..lll.G..spsGplah........ap.t.s.......t.......ph.hhups..otIt..sh.th...................................................ps..hlhshs.ps.thl.h.a..s....s...ph..hhp..h..php...p........h...hph....ptplh.h.l..p..tth...hh.............p..tt.h..th.hpt.........shhh...t....s....hhh..h..us.....lhl..hsht.........hth.........t..l.hlh..t....hh..s..ss.lthh-.+...ph.h.ts....lhsh.h..t..............................................................
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