GenomeNet

Database: Pfam
Entry: WD40_like
LinkDB: WD40_like
Original site: WD40_like 
#=GF ID   WD40_like
#=GF AC   PF17005.5
#=GF DE   WD40-like domain
#=GF AU   Coggill P;0000-0001-5731-1588
#=GF SE   c_1703 - Hirt RP, Nakjang S
#=GF GA   40.00 40.00;
#=GF TC   40.00 40.00;
#=GF NC   39.90 39.90;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 45638612 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Family
#=GF WK   WD40_repeat
#=GF RN   [1]
#=GF RM   24259309
#=GF RT   Reduction and expansion in microsporidian genome evolution: new
#=GF RT   insights from comparative genomics.
#=GF RA   Nakjang S, Williams TA, Heinz E, Watson AK, Foster PG, Sendra
#=GF RA   KM, Heaps SE, Hirt RP, Martin Embley T;
#=GF RL   Genome Biol Evol. 2013;5:2285-2303.
#=GF DR   INTERPRO; IPR031544;
#=GF DR   SO; 0100021; polypeptide_conserved_region;
#=GF CC   This is a family of proteins which have weak homology to the
#=GF CC   WD40 repeat family. Members are largely from microsporidia and
#=GF CC   related species.
#=GF SQ   45
#=GS A0A0B2UNI8_9MICR/3-301    AC A0A0B2UNI8.1
#=GS A0A195EHY2_9HYME/75-309   AC A0A195EHY2.1
#=GS A0A059EK00_9MICR/2-172    AC A0A059EK00.1
#=GS A0A059F3Y3_9MICR/14-299   AC A0A059F3Y3.1
#=GS A0A1R2BX14_9CILI/151-431  AC A0A1R2BX14.1
#=GS A0A0F9WQ95_9MICR/3-301    AC A0A0F9WQ95.1
#=GS A0A1R0GNH1_9FUNG/79-402   AC A0A1R0GNH1.1
#=GS L7JWR4_TRAHO/138-241      AC L7JWR4.1
#=GS A0A195FBV4_9HYME/75-423   AC A0A195FBV4.1
#=GS A0A1X0QBY0_9MICR/4-302    AC A0A1X0QBY0.1
#=GS L2GY11_VAVCU/307-412      AC L2GY11.1
#=GS R0MG28_NOSB1/82-379       AC R0MG28.1
#=GS T0L902_9MICR/9-303        AC T0L902.1
#=GS H8Z9C0_NEMS1/1-158        AC H8Z9C0.1
#=GS B7XMY6_ENTBH/16-78        AC B7XMY6.1
#=GS K9Y0P2_STAC7/1267-1444    AC K9Y0P2.1
#=GS E2A3S1_CAMFO/74-198       AC E2A3S1.1
#=GS B7XN87_ENTBH/16-154       AC B7XN87.1
#=GS S7W9E7_SPRLO/12-317       AC S7W9E7.1
#=GS A0A194QNA3_PAPMA/71-393   AC A0A194QNA3.1
#=GS A0A1W0E4L2_9MICR/6-302    AC A0A1W0E4L2.1
#=GS A0A2A4J622_HELVI/73-397   AC A0A2A4J622.1
#=GS B7XM57_ENTBH/16-92        AC B7XM57.1
#=GS A0A158NKA7_ATTCE/75-408   AC A0A158NKA7.1
#=GS A0A1R0GX25_9FUNG/79-402   AC A0A1R0GX25.1
#=GS L2GY11_VAVCU/161-275      AC L2GY11.1
#=GS F4W8K9_ACREC/1-319        AC F4W8K9.1
#=GS J9JRX6_ACYPI/234-491      AC J9JRX6.1
#=GS L2GJY6_VITCO/20-253       AC L2GJY6.1
#=GS I3EK78_NEMP3/9-336        AC I3EK78.1
#=GS C4VAG3_NOSCE/15-313       AC C4VAG3.1
#=GS A0A177ECB8_9MICR/13-345   AC A0A177ECB8.1
#=GS A0A194PZD0_PAPXU/69-392   AC A0A194PZD0.1
#=GS H9UC95_FERPD/463-726      AC H9UC95.1
#=GS A0A1Y1S6Z9_9MICR/17-321   AC A0A1Y1S6Z9.1
#=GS B7XI71_ENTBH/16-313       AC B7XI71.1
#=GS A0A151I1K2_9HYME/75-224   AC A0A151I1K2.1
#=GS A0A151ZJZ6_9MYCE/103-266  AC A0A151ZJZ6.1
#=GS B7XQH1_ENTBH/16-131       AC B7XQH1.1
#=GS J8ZY85_EDHAE/6-349        AC J8ZY85.1
#=GS Q8SRX6_ENCCU/3-301        AC Q8SRX6.1
#=GS L7JWR4_TRAHO/1-121        AC L7JWR4.1
#=GS A0CJP1_PARTE/211-525      AC A0CJP1.1
#=GS A0A151I7S4_9HYME/76-413   AC A0A151I7S4.1
#=GS A0A1Y1XMQ9_9FUNG/206-480  AC A0A1Y1XMQ9.1
A0A0B2UNI8_9MICR/3-301               ........d-EIYCIDFYA.STRILLYGGKNNKCIAMNVDTGD..V..V..A..VV.E.DFDDSVVFCKFL.DSE....KFIV.GS.LD..GTI--SLMTFEG..........EIN.N.VC.LNEDIAR..M..K..I..IG.D..K..VVV.G..TEVGNIHV........FS.L.D....L.....C.....FQNV.CIG..QH..SEIL..DM.CYE..................................................NGKLYTLT..ADSFV.MFD....S.N.T..HQKLTG..F..KIK...N.......GLC..LDKI..PESDVIC.IGSENMV...VI....S........K..NMNILAKIEV.....EG...L..P.LCALYM..N...N....YFV..I.GGCFE.YILLVNIP..MGM.RV.FKIPL.....GTI.EVWDIRGD..G.LNQIVFST.S....CGLVGHGDIRDEKSFKLFKTDLRSIFDLCFKDQV....VYAAGENGYNVI.............................................
A0A195EHY2_9HYME/75-309              .......ht--VFCCSLSK.NGDLVATGGEDDKGYLWNANTGE..S..I..L.nTG.D.SHNDSVIFSDFN.YND....KYV-.AT.ADmrGKIKLWRISDKT..........CVW.E.TA.LMNDINW..I..K..WhpFS.D..I..LVT.G..GETGEVYM........LK.T.R....-.....K.....DDYK.IFA..QG..SGIK..SE.TGIilpdgtfllkreqntnlnltgkraaigyengmihvidlksntlvsttppdQTRLYGHS..SN-II.ALD....C.YmD..NNLLIS..V..SVE...S.......QTI..LSTV..HNGKVIC.VL-----...--....-........-..----------.....--...-..-.------..-...-....---..-.-----.--------..---.--.-----.....---.--------..-.--------.-....----------------------------------....------------qdlhrh.......................................
A0A059EK00_9MICR/2-172               ........f----------.-----------------------..-..-..-..--.-.------------.---....----.--.--..------------..........---.-.--.-------..-..-..-..--.-..-..---.-..--------........--.-.-....-.....-.....----.---..-S..SSIL..DI.LID..................................................EEMFYLLN..NESLL.IYS....I.D.F..-IEIKR..H..KLK...N.......GQL..FCMM..--NKLIC.VIEESIL...SF....Y........T..IHKKIHEIQI.....QE...V..-.ECMLTM..N...N....YIV..L.GGNFN.YLMLIDCN..--Y.QI.KKINL.....PIE.GSTRIKF-..R.NNLLFISS.S....DDKFCYGDFN---KFKVVESEVGVIFDYALSKEY....YVLAGEKGIS--i............................................
A0A059F3Y3_9MICR/14-299              ........l-EVYSVNISN.SNKEVIFGGGSDNVSVICVESNE..E..I..F..-T.D.TYNESIFYANFT.AD-....GIIV.IV.YD..GTVVFYDINYHK..........-CK.E.HF.FNEEVSV..V..K..E..YK.G..R..YFI.G..FESGRLII........LE.R.Y....-.....E.....IIYD.YTL..FS..SGIL..DI.LID..................................................EEMFYLLN..NESLL.IYS....I.D.F..-IEIKR..H..KLK...N.......GQL..FCMM..--NKLIC.VIEESIL...SF....Y........T..IHKKIHEIQI.....QE...V..-.ECMLTM..N...N....YIV..L.GGNFN.YLMLIDCN..--Y.QI.KKINL.....PIE.GSTRIKF-..S.NNLLFISS.S....DDKFCYGDFN---KFKVVESEVGVIFDYALSKEY....YVLAGEKGIS--i............................................
A0A1R2BX14_9CILI/151-431             .......ks--INSMVISD.DNKYIISGSSDKTIRIWDLNNQK..L..D..F..IL.T.GHKDNVNCVVIS.SDS...tLIAS.CS.HD..YTIKLWDFKLKQ..........EIC.MlKG.HTENISS..L..A..I..SK.D..KtlLVS.G..SWDFSVII........WN.L.N....T....kN.....IENV.FYG..HN..NIVS..CV.AIT..................................................DNKKYIASgaGDHTI.RIW....S.V.N..EKKLIH..V..LEK...H.......TNI..VRCIafRSNGKVL.LSGSADA...TI....I........C..WNLLEEKINFcfkghRS...E..I.LCIGISrnD...K....YLI..S.GSSDK.TVKIWNID..EAR.LE.YTIAD.....NND.YICSIAIT..TdSKKIVYCS.A....DSIISI----------------------------....------------wnl..........................................
A0A0F9WQ95_9MICR/3-301               .........SEIYSIDYSF.KSSYFLYGGNDQQCTIFSTRSNT..I..V..S..II.E.GFSESVIFCKLL.SDN....LILV.CS.ID..GYILTTDLNNSF..........-TS.T.TQ.INEEISC..V..H..T..TD.N..H..FYI.G..TYTGTIYKi......hYK.E.D....I.....N.....CQEV.LMG..HG..TEIL..SI.ISD..................................................NNIIYTLS..SLYFI.KY-....-.I.N..NNIEYK..I..NLV...D.......GVS..FSII..PDTEIFC.ICTSSDI...LI....Y........K..KDILIKKISS.....EY...Q..P.ECVIYT..E...G....YFV..V.GGYCD.YLLLINTN..MNM.VT.YKYSL.....VSS.GVNKLIS-..K.SYKVYFST.T....CGYVGSCDIRKDDTVEMYESKVGTVFDMCVNNDT....FYIGGLNGVDIL.............................................
A0A1R0GNH1_9FUNG/79-402              .........EPVYSVAINPvDTNIVVSGGGDDTAYVWRRDTGE..L..V..Q..KL.D.KHSDSVTAVGFS.VDG...qYVAS.GG.MD..GKIKVYKTNPIT.........pHFV.F.ED.GPDEVVW..LdwH..P..VG.N..V..FAV.G..ANDGSVWM........YN.VpG....K.....K.....LMNV.FYG..HN..EPVT..TG.RFTh...............................................sgKNIISGSE..DGSLI.IWN....P.A.N..ASVVHK..F..SSE...DkrfhqegITS..LDIN..-SDDSII.ISGSTDStakVL....H........K..NGNILGSLQA.....HS...D.sV.ETVGIS..S...A....MSMaaT.GSVDG.SICVWDINtlRLR.DT.FK---.....HED.AVTKLKFV..N.NSPLITSTsV....DCTVKVWDSRSGENVRTWKGHQDAILDFALVGD-....------------gktvvtasddgcclv..............................
L7JWR4_TRAHO/138-241                 ...shvydi----------.-----------------------..-..-..-..--.-.------------.---....----.--.--..------------..........---.-.--.-------..-..-..-..--.-..-..---.-..--------........--.-.-....-.....-.....----.---..--..----..--.---..................................................--------..-----.---....-.-.-..------..-..---...-.......---..----..-------.-------...--....-........-..--------SS.....NA...-..T.ECIAKI..N...D....DLV..I.GGEY-.-LMVM-VK..--G.RE.--HRT.....AVQ.HVNLLVV-..S.NTIVVFAT.L....DGQIGIGDYREE-QFSMCDGGVGLVYDMVLCGNV....VYVAGENGTN--ei...........................................
A0A195FBV4_9HYME/75-423              .......ht--VFCCSLSK.NGDLAATGGEDDKGYLWNASTGE..S..I..L..NTdD.SHNDSVIFSDFN.YND....KYV-.AT.ADmrGKIKLWRISDKT..........CVW.E.TA.LMNDINW..I..K..WhpFS.D..I..LVT.G..VETGEVYM........LK.T.R....-.....K.....DDYK.IFA..QG..SGIK..SE.TGIilpdgtflfkreqninlnlagkravigyengmihvidlksntlvsttppdQRRLHGHS..SS-II.ALD....C.YmD..NNLLIS..V..SVE...S.......QTI..LSTI..HNGKVIC.VLQDLRR...RG....N........N..NDHIEIAAFC.....KD...-..-.PTFPVA..A...S....ATV..T.SETYG.KIYIWDIS..K--.QS.LRNEM....dQEG.GITKLVWT..K.ASIFFTAG.L....DGKLRCFDAKIGHCLRIFSGHKGALYDLCISSD-....------------ekkaitvsddg..................................
A0A1X0QBY0_9MICR/4-302               ........k-EVYSIDL--.KDNYLCLSTSGPGVEMYNLETSE..L..I..F..KE.E.PFDSAICLVKFV.DDN....NLFV.LT.EM..GEI--TLIRNYNsi.....kdlDYE.T.VD.FKSNVTE..S..I..C..IE.N..K..VLI.G..TQEGEIHV........FD.I.K....-.....T.....METT.YFQqyHK..AQVT..QI.ELM..................................................NGDLVSLS..DVSLV.I-D....S.F.K..NKIMTQ..K..FKI...P.......LET..FSYI..-GNNIYA.LASGSKI...FI....F........N..NKKLLWEYSI.....EN...V..-.HTMKNE..N...N....FLY..A.GGDFN.FILVIDLK..-NY.RT.FKISV.....ET-.TINEIRIIrnV.LFFVSYEP.I....IGWLPTNNFNDIKYINLIN-EMDNIFDFAVNDKF....IVIGGDNGH---fvf..........................................
L2GY11_VAVCU/307-412                 .....cftn----------.-----------------------..-..-..-..--.-.------------.---....----.--.--..------------..........---.-.--.-------..-..-..-..--.-..-..---.-..--------........--.-.-....-.....-.....----.---..--..----..--.---..................................................--------..-----.---....-.-.-..------..-..---...-.......---..----..-------.-------...--....-........-..----LYNINV.....KG...T..-.ECIAKI..N...D....GLV..I.GGEF-.-LVIISQG..---.KE.YRT--.....EIK.DVNLLM-V..R.DSTVIFTT.L....HDQIGVGDYRG-EHFTLYDTDVGLVYDMAIDGNV....VYVAGESGMDHI.............................................
R0MG28_NOSB1/82-379                  .........EEVYNINFSF.NN--ISYGSNRHTCTLYSLENDC..P..V..S..LF.E.GFSDSVIYSKQL.EEN....LILV.CT.ID..GTI--SLLSHDQ..........IIQ.S.EK.IEEDITF..A..E..V..IK.D..K..IYI.G..GSLGSIYV........FN.L.D....L.....S.....SQNV.YLG..HG..SDIH..KI.SYS..................................................NSTIYSLS..DTQFI.AFD....E.F.S..FQQKYK..K..NFK...E.......AKI..FESF.gENQEIFC.IGKEGEV...VI....L........K..NGFILHKFPV.....QG...I..P.ECILFA..Y...D....HFI..V.GGSFP.FLILINTK..LNW.RE.YKLNL.....KIE.GSTKIQKI..N.DFKIAIST.M....CGLVGIGDIRKDDSFEFKESGVGSVFDFQFINGK....FYVGGAFGFDVV.............................................
T0L902_9MICR/9-303                   ........n-EIYTVDYNK.NSNTLMFGGNNQKCTIFDTASNY..K..I..S..EI.E.GFTDSVIFVKHL.QHD....TYLI.CT.LD..GNILITTSKEE-..........-KY.T.LC.INEEISF..V..E..F..FN.N..T..LII.G..TMNFVIYK........FD.I.DnnwsL.....I.....NQTI.HFG..HS..SEIQ..QI.KYD..................................................NNLIYSLS..VYSFI.VFD....A.K.T..STCLLK..H..KLM...N.......SIC..FSYI..PNTELYC.IGTHEYI...LF....Y........K..STNLINKIPM.....EG...H..P.ECICYL..N...E....YFV..V.GGYFN.YLILINTK..MNL.QT.YKISI.....ETT.GINKIIPI..L.NYTVAFST.L....CGFVGTCDIRKSDSIQLFETKVDVIFDFNFYKNI....FL----------le...........................................
H8Z9C0_NEMS1/1-158                   .......mt----------.-----------------------..-..-..-..--.-.---------EFV.SSD....KAVA.VS.MD..GTVASIAIKKEHgg.....ytkEIK.T.VD.VQMDITK..A..V..V..SK.D..KqrLYI.G..TADGLVEE........LP.N.S....IdeiggR.....AVKV.YAG..HS..SEIQ..DI.LES..................................................DTCLYTVS..SGQII.VFN....K.E.T..GSVSAR..Y..NAE...-.......---..----..-------.-------...--....-........-..----------.....--...-..-.------..-...-....---..-.-----.--------..---.--.-----.....---.--------..-.--------.-....----------------------------------....------------ldsdirvvqinstgkslgvgygngslvilsysp............
B7XMY6_ENTBH/16-78                   .........TPIYAVDV--.KGNYILVGGKDENAAVYTVDNGD..L..I..T..IV.A.DLEESVMFCKML.DDHd..vLYLV.--.--..------------..........---.-.--.-------..-..-..-..--.-..-..---.-..--------........--.-.-....-.....-.....----.---..--..----..--.---..................................................--------..-----.---....-.-.-..------..-..---...-.......---..----..-------.-------...--....-........-..----------.....--...-..-.------..-...-....---..-.-----.--------..---.--.-----.....---.--------..-.--------.-....----------------------------------....------------spmmt........................................
K9Y0P2_STAC7/1267-1444               ......wvn----TIDFAS.DN-LLASGGEDNQIKLWEINNQT..SkeI..R..TI.T.GNQDRVTQVKFSaDGN....ELIS.AS.GD..GEVKLWQVKDGK..........QIN.Y.FS.HQEQVNS..V..A..F..TP.D..N..QLI.AtaTADGRINI........WN.K.D....G.....I.....LQQV.LVG..HR..GEIT..DL.NFS..................................................--------..-----.---....-.-.-..------..-..---...-.......---..----..-------.-------...--....-........-..----------.....--...-..-.------..-...-....---..-.-----.--------..---.--.-----.....---.--------..-.--------.-....----------------------------------....------------pieingnknqtqsyllasasvdktvkiwqinnlsaseaggiysva
E2A3S1_CAMFO/74-198                  .......hs--VFCCSLSK.NSELAATGSEEDKAYVWNIITGE..I..I..L..EC.T.GHKDSVIFSGFN.YND....MYLA.TGdMG..GIVKLWQISNKV..........CVW.E.TA.L-DDITW..I..KwhT..SA.N..I..LLV.G..LETGEVHM........FK.L.-....-.....-.....----.---..--..----..--.---..................................................--------..-----.---....-.-.-..------..-..---...-.......---..----..-------.-------...--....-........-..----------.....--...-..-.------..-...-....---..-.-----.--------..---.--.-----.....---.--------..-.--------.-....----------------------------------....------------pegackvfaqgygd...............................
B7XN87_ENTBH/16-154                  .........TPIYAVDV--.KGNYILVGGKDENAAVYTVDNGD..L..I..T..IV.A.DLEESVMFCKML.DDHd..vLYLV.VT.ND..GLI--CLMKLDQ..........SVE.I.TK.RNEAITT..C..K..Y..TG.G..E..LLI.G..TETGQIHV........LS.K.E....-.....L.....LVTT.TLS..WN..TPIK..EV.EKI..................................................NNYIFGLV..EMHL-.---....-.-.-..------..-..---...-.......---..----..-------.-------...--....-........-..----------.....--...-..-.------..-...-....---..-.-----.--------..---.--.-----.....---.--------..-.--------.-....----------------------------------....------------.............................................
S7W9E7_SPRLO/12-317                  .........TEIYSLDINK.DSTYIIYGGKDDKCRILDFNTLE..E..K..Y..II.D.IFKDSIQHVNFL.DND....HFIV.VT.LD..GAFMEYKIINENl........qVIR.E.EK.IKNDVST..V..C..N..LD.K..K..IAI.G..TNVGEIYY........YN.N.D....-.....-.....FEMV.FSN..HS..SEIL..EL.KIH..................................................ENFLFSLS..VDALI.VYN....L.D.S..FSLHRR..I..GIR...N.......IEN..FHIT..NFQNIFL.LSFNDHI...KI....L........K..RNEILQRIDM.....KG...K..P.LCFLNS..D...D....LVF..V.GCDTK.YICLLNFK..ANV.NT.FYIDCvdgeeDIE.GITHIKII..N.SFFIVFST.L....CGKIGFGDFRDKNTFLYQKCCEGVILSFEIRDNI....IFWYGESGFGVL.............................................
A0A194QNA3_PAPMA/71-393              .......gs--VFCCNLHP.DGKFAVTGGEDDKAYVWSTETGQ..I..I..T..EC.A.GHKDSVIFVGFS.FDG....AFLAsVD.MS..GVIKVWKCNFEStq......ewPVAfE.YE.AGDLIWG..L..W..H..FG.A..R..VLIcG..AASGDIFV........FK.I.P....S.....G.....DTKI.LPG..HNvkTECG..KL.FSD..................................................GVRLVSGY..EDGTVkVWD....L.K.T..NSVLHQvpQ..NVH...Q.......IRV..TDVDthPENNVMAsISTDGKA...VL....T........TsvNGKVVAQLET.....DN...D..L.EAVAFS..NpqlG....YLA..L.GTLNG.SVTIWDAG..RQM.IR.HYCSKke.dgVAA.GVTKIFWI..N.DQLVT-GC.L....DGSIRIYDGRSGERSLMLTGHWLEIFDICYNEK-....------------qnillstsddgt.................................
A0A1W0E4L2_9MICR/6-302               ........g-EFYSVDI--.GNTYFLVGGCNDEAVLYKKEGEA..I..K..T..IV.D.NLEESVMYVKIL.QETekecLFML.AT.VG..GLA--CLMTNNK..........AIE.I.VD.LKENISF..C..T..F..IN.N..V..FYI.G..TEIGNVYV........YS.H.D....F.....E.....HLN-.TMS..AN..VTVI..DI.QIN..................................................NTSVGVLC..ENKIC.IGD....S.Y.G..-NVIFE..K..YIP...D.......ISS..FVFL..-NGNVFA.FTAGRNF...AI....Y........K..EHNKLFETTF.....EE...E..A.DSVVLV..D...D....SFV..I.GGSFD.GIYCVNIN..-NY.SI.YKIDI.....GIN.MIKDIKVI..G.KYLVSFIQ.G....ENKIGVLDIRDKSSLRLYESMAEFIFSYGILGNE....IVIGGIKGYEY-i............................................
A0A2A4J622_HELVI/73-397              .......gs--VFCCDLHP.EGKLAVTGGEDDRAYVWSVENGQ..L..V..M..DC.T.GHKDSVIFAGFS.FDG....AYLAtAD.MS..GLIKVWKCNLEEnqq....tpwTVA.F.EY.EADDLTWglW..H..F..GA.R..V..LIF.G..TESGDIYV........FK.V.P....S.....G.....DTKV.LQG..HN..TKVEcgKL.FHD..................................................GVRLAAGY..EDGVVkIWD....L.K.T..SAVLHQlpA..SVH...Q.......IRItaIDTH..PDDNLMAsISTDGKV...VL....T........TpnNGKVVGQLET.....EN...D..L.ETVAFA..Q...DtqlgFLA..T.GTLTG.AVGIWDVA..RQM.IR.HQCAKs..ddAVG.GVTKMVWV..K.-NHLVTGC.L....DGSVRVYEGRTGERTQMLTGHRSEVLDLCFNPK-....------------qslilttsddgt.................................
B7XM57_ENTBH/16-92                   .........TPIYAVDV--.KGNYILVGGKDENAAVYTVDNGD..L..I..T..IV.A.DLEESVMFCKML.DDHd..vLYLV.VT.ND..GLI--CPMKLDQ..........SVG.N.--.-------..-..-..-..--.-..-..---.-..--------........--.-.-....-.....-.....----.---..--..----..--.---..................................................--------..-----.---....-.-.-..------..-..---...-.......---..----..-------.-------...--....-........-..----------.....--...-..-.------..-...-....---..-.-----.--------..---.--.-----.....---.--------..-.--------.-....----------------------------------....------------t............................................
A0A158NKA7_ATTCE/75-408              .......ht--VFCCSLSK.NGNLVATGGEDDKGYLWNANTGE..G..I.lS..TG.D.SHNDSVIFSDFN.YND....KYV-.AT.ADmrGKIKLWRISDKT..........CVW.E.TA.LMNDINW..I..K..WhpFS.D..I..LVT.G..VETGEIYM........LK.T.R....-.....K.....DDCK.IFA..QG..SGIK..SE.AGIilpdgkravigyengmi................hvidlksntlvsntppdQTRLYGHS..SS-II.ALD....CyI.D..NNLLIS..V..SVE...S.......QTI..LSTV..HNGKVIC.ILQDLHK...RG....N........N..NDHVEVAAFC.....KD...-..P.-TFPVA..A...S....ATV..T.SETYG.KIYIWDIS..KQS.LR.HEMD-.....QEG.GVTKLVWI..K.ASIFFTSG.L....DGKLRCFDARIGHCLRIFSGHKGALYDVCISSD-....------------ekkaitvsddgt.................................
A0A1R0GX25_9FUNG/79-402              .........EPVYSVAINPvDTNIVVSGGGDDTAYVWRRDTGE..L..V..Q..KL.D.KHSDSVTAVGFS.VDG...qYVAS.GG.MD..GKIKVYKTNPIT.........pHFV.F.ED.GPDEVVW..LdwH..P..VG.N..V..FAV.G..ANDGSVWM........YN.VpG....K.....K.....LMNV.FYG..HN..EPVT..TG.RFTh...............................................sgKNIISGSE..DGSLI.IWN....P.A.N..ASVVHK..F..SSE...DkrfhqegITS..LDIN..-SDDSII.ISGSTDStakVL....H........K..NGNILGSLQA.....HS...D.sV.ETVGIS..S...A....MSMaaT.GSVDG.SICVWDINtlRLR.DT.FK---.....HED.AVTKLKFV..N.NSPLITSTsV....DCTVKVWDSRSGENVRTWKGHQDAILDFALVGD-....------------gktvvtasddgcclv..............................
L2GY11_VAVCU/161-275                 .ryllikka----------.-----------------------..-..-..-..--.-.------------.---....----.--.--..------------..........---.H.QN.IRKDITS..V..T..H..HG.N..I..LLL.G..CEDGCIHV........FY.K.N....L.....Q.....CHTN.LEG..HK..TEIN..GL.SIL..................................................NNYIFSSS..AGNFI.VYK....N.N.F..--VVY-..-..---...-.......---..----..-------.-------...--....-........-..----------.....--...-..-.------..-...-....---..-.-----.--------..---.--.-----.....---.--------..-.--------.-....----------------------------------....------------nhktdllkgmhmidgraylvyeegisvlkyne.............
F4W8K9_ACREC/1-319                   ........m----------.-----ATGGEDDKGYLWNTNTGE..G..I..L..STdD.SHNDSVIFSDFN.YND....KYVV.TAdMR..GKIKLWRISDKT..........CVW.E.TA.LMNDINW..I..K..WhpFS.D..I..LVT.G..VETGEVYM........LK.T.R....-.....T.....DDCK.IFA..QG..SGIK..SE.AGIilpdgkraaigyengmi................hvidlksntlvsttppdQTRLHGHS..SN-II.ALD....C.YmD..NNLLIS..V..SVE...S.......QTI..LSTV..HNGKVIC.VLQDLHR...RG....N........N..NDHVEIAAFC.....KD...-..P.TFPAAA..S...-....ATV..T.SETYG.KIYIWDIF..KQS.LR.HEMD-.....QEG.GVTKLVWT..K.ASIFFTSG.L....DGKLRCFDARIGHCLRIFSGHKGALYDVCISSD-....------------ekkamtvsddg..................................
J9JRX6_ACYPI/234-491                 .......gg--VYGVAWSA.DSTRLLTSSGDKTCKLWDVETKS..V..V..SefVIgN.QVED-QQVSCLW.QGN....YLLT.VS.LN..GFITYLDVNNPE.........kPIR.I.IKgHNKPITV..L..A..L..SP.DrsT..IYT.G..SHDGNITN........WN.A.A....N....gE.....NDRVkGVG..HG..NQIN..GM.KLD..................................................NDYLYTCG.iDDSLR.QVD....V.K.S..-NSYTD..L..QVK...L.......NAQ..PRGM.dFNSNVIV.TVTIKEI...IV....L........K..NEKKVFNLPV.....DY...E..P.SAVAISpgA...G....YVA..V.GGALD.NKVH-VYK..INE.ST.YNLEF.....VAE.--------..-.--------.-....----------------------------------....------------cdhlgpitdcs..................................
L2GJY6_VITCO/20-253                  ........d-ELYTVDICP.SKKHVIFGGKSETAEVYSYEEER..A..I..T..RI.E.EFSDSVIYAKFV.SEN....RFVI.VT.TD..GTI--ALMEHSG..........DVC.I.VD.LEEDISV..A..K..F..-S.E..K..LVV.G..ASSGRVYL........YD.A.C....L.....E.....HINT.LGG..HS..SEII..SV.DYK..................................................EGRILSMC..ANYLI.AHD....E.Q.G..-RVLYT..L..KAS...E.......AYA..FKYI..-TSDVIC.FARDGKI...QI....F........K..QTRKLFEHNI.....EE...R..V.EDVEIV..G...K....SLA..V.GGEFD.YILLIDTT..GHY.AT.FKLDV.....KTE.--------..-.--------.-....----------------------------------....------------lt...........................................
I3EK78_NEMP3/9-336                   .........EEVYCIDTCK.ETNMVISGGGDDAVTFHVFNGES..Y..VidE..VI.E.GFEDSVIMTEFI.SSD....KAIA.VA.MD..GTIAEINLIKENgr.....ytkDVN.I.VC.LQMDITK..AvlS..K..DK.K..R..IYI.G..TADGLVEE........FP.A.D....I.....AaiearAVRI.YAG..HS..SEIQ..DI.LES..................................................DSFLYTVS..GTHII.IFS....K.G.TgsVSARYK..A..EFE..tD.......IRA..VQIN..KTGKTVA.VGYGNGT...LV....LlsyspeqgK..LTNVYQNTQT.....ER..eS..V.ESLAFF..E...D....TLI..Y.GDFSS.TVSILNIK..YKTeRV.CKLSE.....DKE.CVVKIITV..S.EAVAMAIT.N....AGKVCVFSLKMDNTMI------------------....------------ceyalssitlnavvfnrficaatvegiefl...............
C4VAG3_NOSCE/15-313                  .........SEIYSIDYSF.KSSYFLYGGNDQQCTIFSTRSNT..I..V..S..II.E.GFSESVIFCKLL.SDN....LILV.CS.ID..GYILTTDLNNSF..........-TS.T.TQ.INEEISC..V..H..T..TD.N..H..FYI.G..TYTGTIYKi......hYK.E.D....I.....N.....CQEV.LMG..HG..TEIL..SI.ISD..................................................NNIIYTLS..SLYFI.KY-....-.I.N..NNIEYK..I..NLV...D.......GVS..FSII..PDTEIFC.ICTSSDI...LI....Y........K..KDIIIKKISS.....EY...Q..P.ECVIYT..E...G....YFV..V.GGYCD.YLLLINTN..MNM.VT.YKYSL.....VSS.GVNKLIS-..K.SYKVYFST.T....CGYVGSCDIRKDDTVEMYESKVGTVFDMCVNNDT....FYIGGLNGVDIL.............................................
A0A177ECB8_9MICR/13-345              .........EEVYAMGYTG.LLNMIISGGGDDAITLHVRDGLDyqI..G..E..VI.E.GLDDSVIFATFV.RGM....NPVA.VT.MD..GTVVYLDIDSPEtlkcvehfeeNIH.P.VS.LNLDVST..A..AlsS..CE.S..W..LYI.G..TTDGAITRvsaslpppYT.Q.D....-.....-.....THAV.YMG..HP..SDVL..VI.EAV..................................................NEVIYTAS..HTQVI.LFC....A.E.T..GATLKK..Y..LSQeegE.......IRT..MKVH..PTGKVVA.LGYSTGA...VV....Llsn..sqtT..NQGLLTVYRA.....EM...SlpV.ESLAFV..E...D....KLL..Y.GGFDS.VLKVVDLK..YKT.ETeCAFKE.....DAS.CIVKIIPL..N.ASIAIAAI.T....NGKVFIVDIRTNNKILKEFSIPCTITDIMLCGNL....LCAATSEGVEV-i............................................
A0A194PZD0_PAPXU/69-392              .......gs--VFCCNLHP.DGKFAVTGGEDDKAYVWSTETGE..I..V..T..EC.T.GHKDSVIFVGFS.FDG....AFLAsVD.MS..GVIKVWKCNFEStq......ewPVAfE.YE.AGDLIWG..L..W..H..FG.T..R..VLIcG..AVSGDIFV........FK.I.P....S.....G.....DTKI.LPG..HNvkTECG..KL.FSD..................................................GVRLVSGY..EDGTVkVWD....L.K.T..NSVLHQ..VppNVH...H.......MRVtdVDTH..PENNIMAsISTDGKA...VL....T........TsmNGKVVAQLET.....DD...D..L.ETVAFS..NpqlG....FLA..L.GTLNG.SVSIWDAG..RQM.MR.HYCSKke.dgVSA.GVTKIFWI..N.DQLVT-GC.L....DGSIRIYDGRSGERILMLTGHWLEIFDMCYNEKQ....------------nillstsddgta.................................
H9UC95_FERPD/463-726                 nlktiavis----------.-----------------------..-..-..-..--.-.------------.---....----.--.--..------------..........---.-.--.-EEWICS..I..Y..N..SE.G..I..LYV.G..TNLGNVYA........LD.K.M....S.....Y.....KPKL.INS..YP..SPVV..KI.SRLnsqivvfhfngtiavfdg.............kvwkvqrsdvfplysglviE-------..-SQII.TGGsklrI.G.N..SSYEFE..A..FIV...D.......LAE..FRKT..-KNNIFA.SLSNGMV...VQ....I........E..DGNVVRRFSS.....QI...S..S.ISTIYA..D...D....LVI..C.GHEDG.KVSLWNYN..KKQ.AK.FELSMif.ddHTD.AVKSITRY..K.KYIISA-S.N....DKTIKVWDSKTGKLLNILTGHTGYVWSIFVVGDI....LVSGGWDGK---vil..........................................
A0A1Y1S6Z9_9MICR/17-321              ........d-EVYTVSI--.ANSVIAVGGGNESVVLSDIKSEE..I..L..L..VS.D.SFGESIVFCKII.EKSaddvKFIV.VT.VD..GMI-YCISKIEH..........VLD.L.VQ.IDESVST..C..A..F..ID.S..C..LLV.G..AESGKIYA........YS.D.H....I.....E.....HINT.-IS..GD..SQII..DI.DKN..................................................GDQYYGLS..VNQVI.VGD....Q.Y.G..-NILFR..K..MLD...N.......PNC..IKAV..-SGGVFA.VGTDKKV...FI....F........K..NNTKLMEYST.....GG...A..V.ESICIS..E...R....SFV..L.SGQFD.GLIVISMA..-NY.SV.FNMKM.....GME.-MSNLRHV..S.TYGLLFTT.IiqdnEQYVGYLDVRDKNSCRKQPVSVGHVFDIAFELNNngitTVLGGELGHEVV.............................................
B7XI71_ENTBH/16-313                  .........TPIYAVDV--.KGNYILVGGKDENAAVYTVDNGD..L..I..T..IV.A.DLEESVMFCKML.DDHd..vLYLV.VT.ND..GLI--CLMKLDQ..........SVE.I.TK.RNEAITT..C..K..Y..TG.G..E..LLI.G..TETGQIHV........LS.K.E....-.....L.....LVTT.TLS..WN..TPIK..EV.EKI..................................................NNYIFGLV..ENALI.VGD....V.Y.G..-NIETV..Y..DVH...G.......IQC..FQCI..-NKNIIA.IGTNTKF...LI....Y........C..GKKLLFELDT.....EA...V..-.ETIAIW..K...H....ICI..L.GGGFN.GLKIINMN..-NY.SH.YTILM.....ENI.YVRMIKYV..C.EFVVIYIT.Y....DNFVGVMDIRDKMTLRLLDPELGDIYDIAYELNMqiinIVVGGEYGYKHF.............................................
A0A151I1K2_9HYME/75-224              .......ht--VFCCSLSK.NGNLVATGGEDDKGYLWNANTGE..G..I..L..STdD.SHNDSVIFSDFN.YND....KYV-.AT.ADmrGKIKLWRISDKI..........CVW.E.TA.LMNDINW..I..K..WhpFS.D..I..LVT.G..VETGEIYM........LK.T.R....-.....K.....DDCK.IFA..QG..SGIK..--.---..................................................--------..-----.---....-.-.-..------..-..---...-.......---..----..-------.-------...--....-........-..----------.....--...-..-.------..-...-....---..-.-----.--------..---.--.-----.....---.--------..-.--------.-....----------------------------------....------------seagiilpddfcsrenvicilq.......................
A0A151ZJZ6_9MYCE/103-266             dpinslisk----------.-DFMVFTGDDEGTIKVWDMRQQN..I..V..C..EF.Q.EHGDYISDIITL.DDK....HFVS.TS.GD..GGLSIYNFVRHSm........eDIS.E.KS.DNELLSV..I..A..M..DNeK..K..LVC.G..SQEGQIYI........FDrN.N....L.....E.....KPQK.FVG..HP..ESVD..SLvKIN..................................................EQTLFTGS..EDGMI.RY-....-.-.-..------..-..---...-.......---..----..-------.-------...--....-........-..----------.....--...-..-.------..-...-....---..-.-----.--------..---.--.-----.....---.--------..-.--------.-....----------------------------------....------------vgikpkkllgvvgehs.............................
B7XQH1_ENTBH/16-131                  .........TPIYAVDV--.KGNYILVGGKDENAAVYTVDNGD..L..I..T..IV.A.DLEESVMFCKML.DDHd..vLYLV.VT.ND..GLI--CLMKLDQ..........SVE.I.TK.RNEAITT..C..K..Y..TG.G..E..LLI.G..TETGQIHV........LS.K.E....L.....L.....VTTT.---..--..----..--.---..................................................--------..-----.---....-.-.-..------..-..---...-.......---..----..-------.-------...--....-........-..----------.....--...-..-.------..-...-....---..-.-----.--------..---.--.-----.....---.--------..-.--------.-....----------------------------------....------------ls...........................................
J8ZY85_EDHAE/6-349                   .........EELYSIDISK.NGQLIAFGGKSDTLTLAKFPSLI..S..I..T..SE.T.SFTDSIIYVKFI.LND....VILC.AT.LD..GNLSLHVLENGEl........vEVD.N.RD.LEEDISF..I..D..V..IN.D..L..VVV.G..TNKGSIHI........FS.Q.D....L.....Q.....NEIL.FVG..QH..SEIR..DI.KIIfdesfinnnencdnnilqae.........nainekkivetdeneyfgsnfKGKLYSLS..ESHYM.IFD....L.F.T..QGTLYK..R..SYK...D.......FRT..FNIV..-NKDLLF.IGNEGES...LL....I........K..DNVVLQKYLF.....GS...-..-.ECTALV..D...D....YLV..S.GGSGF.SLTIINIK..SPS.NC.FNLRFl..aeNVE.GISKIVRL..S.KNIVGIAT.F....CGKIAIGDVRSGETFKFYDCGVGIIYDMKFFRNY....VAVCGNAGLRIV.............................................
Q8SRX6_ENCCU/3-301                   .........SEVYTVDLNP.RGSMVAYGGGNDRCTVMDLETGD..V..V..S..IV.E.NFGDSVIFCKFI.DGE....KLLV.GS.LD..GTI--SLMTLEE..........EIN.N.VS.VNEDISK..I..K..V..DK.D..K..LLV.G..TTRGNVHL........FS.L.D....L.....C.....IQNV.CIG..QY..SEIQ..DM.CYE..................................................SGRAYTLS..ETNFM.VFD....A.E.S..HRKLMD..L..HVR...G.......GSA..IGKM..PSSDVVC.LGLEGCI...VV....R........K..NAHLLGRIEV.....DG...S..P.ECILYM..N...N....YFI..V.GGDFD.YILLINMP..MSM.RT.FKIPV.....GVE.GISGIRGD..G.ENRIAFST.C....NGAVGYGDIRDEKSFKLIEGGVGCIFDMCFKGDT....IYVGGEHGFNAL.............................................
L7JWR4_TRAHO/1-121                   .....vker----------.-----------------------..-..-..-..--.-.------------.---....----.--.--..------------..........---.-.RC.LHKDISF..V..T..H..HK.N..I..LLI.G..CTDGEIHL........FY.K.N....L.....Q.....HHIN.LAG..HK..SEIT..AL.SIL..................................................NNYVFSCS..AQNFI.VY-....-.K.N..NSVVHN..H..KTN...E.......LKG..MRVI..--DDRIY.LMYNHCI...RV....L........K..HDA-------.....--...-..-.------..-...-....---..-.-----.--------..---.--.-----.....---.--------..-.--------.-....----------------------------------....------------cfstsynekey..................................
A0CJP1_PARTE/211-525                 ...qnpvsk----------.--DLIASGSEDDHLKIIKLSTQK..V..I..-..FE.K.KYDETVGLVDFN.YDG....KYLA.AGiLT..GKIYIYLLNDMSe........kMLD.G.SQ.TEPSVLK..W..H..P..KG.N..V..ILA.G..FQDSTLWM........WN.G.V....T....gE.....VMSV.FAG..HE..AEIT..--.--Cggftldgk.................................livsgsadqSFRVWKPS..TSE-Q.VYK....I.S.S..VSHKHN..Y..HKD...D.......VVC..FVQH..YKQPIIA.TGSSDST...IAf.inF........E..DGKVIGKSDP.....LGdsiV..E.LCFIGT..N...Q....PII..V.AGDMSgSVYIYNWN..SMK.LI.EKLCL.....CKN.SITKILFY..N.-QQFHISS.L....DGKIVTFDVRQMHNYRVLQAKSG-IYEMIVEEGW....ILVGCENGFV--yv...........................................
A0A151I7S4_9HYME/76-413              ......hiv---FCCSLSK.NGDLMATGGEDDKGYLWNTNTGE..S..I..F..NT.DgSHDDSVIFAEFN.YND....KYLAtAD.MC..GKIKLWRISDKT..........CVW.E.TV.LMNDINW..I..K..WhpFS.D..I..LIT.G..TETGEVYM........LK.T.R....-.....K.....DDCK.IFA..QG..TGIK..TE.AGVilpdgkraaigyengmi................hvidlksntlisttppdQTGLHGHS..ST-II.ALD....C.YmD..NNLLIS..V..SME...S.......QTI..LSTA..HNGKVIC.ILQDLNK...HG....D........N..KDHV-EVVAF.....CK...D..P.TFPAAA..S...A....TVT..SeTCGKI.YIWDISKQ..IPF.QN.LRHEI.....NQEgGVSKLVWT..K.TSIFFTAG.L....DCKLRCFDARAGHYLRVFSGHRGALYDICISSD-....------------ekkavtvsddgt.................................
A0A1Y1XMQ9_9FUNG/206-480             .....nnkk----------.----------------------Y..S..I..Y..NM.V.SHTDSI-YCLQY.NNE....RIIS.GS.RD..QTIKVWDLKTNE..........CIK.T.LNgHTGSILS..L..Q..F..DA.N..Y..LVT.G..SSDSTIIL........WD.I.K...sF.....E.....IVRR.ITG..HQ..DSVL..SV.KFN..................................................KDYIVSSS..KDHTIrIWD....I.K.T..GEFVRK..L..EGH...K.......TVA..NAIQ..-LKGDII.VSASGDR...LIrawsL........S..TGKLLKTFEG.....HT...R..GiACIFFD..G...N....III..S.GSSDC.TLKVWDFH..SNK.LL.FTLYG.....HTE.LVRTIQFD..G.K-KIVSGS.Y....DRTIKIWDFKSKQLLFSLDGHLSKIFCLQFSDSK....IISC--------ssdkh........................................
#=GC seq_cons                        ...........lashsh...psphlhhGGp--pshlashpstp..h..l......h.p.sap-SVhasph...ss....hhls.so.hD..GhI..h.hp.pp..........tlt...hp.hpcsIsh..h..p..h..hs.s..h..lll.G..spsGplah........ap.t.p..........p.......ph.hhu..as..otIt..sl.th...................................................pshlashs..psthl.hhs........s...phhhp..h..php...p............hphh...psplhh.l.tptth...hh....h........p..ptthh.ph.h.....pt.........shhh...p...t....hhh..h.Gs..t..lhlhsht.......h.hph.........t.hlpplh....t.t.hhhhts......ss.lthhDh+....h.h.pst.t.lhsh.h..p..............................................................
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