GenomeNet

Database: Pfam
Entry: YopD
LinkDB: YopD
Original site: YopD 
#=GF ID   YopD
#=GF AC   PF05844.14
#=GF DE   YopD protein
#=GF AU   Moxon SJ;0000-0003-4644-1816
#=GF SE   Pfam-B_8937 (release 8.0)
#=GF GA   25.00 25.00;
#=GF TC   26.70 50.20;
#=GF NC   24.10 24.20;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 57096847 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Family
#=GF RN   [1]
#=GF RM   8418066
#=GF RT   YopB and YopD constitute a novel class of Yersinia Yop proteins. 
#=GF RA   Hakansson S, Bergman T, Vanooteghem JC, Cornelis G, Wolf-Watz H; 
#=GF RL   Infect Immun 1993;61:71-80.
#=GF DR   INTERPRO; IPR008898;
#=GF DR   SCOP; 1kdl; fa;
#=GF DR   SO; 0100021; polypeptide_conserved_region;
#=GF CC   This family consists of several bacterial YopD like proteins.
#=GF CC   Virulent Yersinia species harbour a common plasmid that encodes
#=GF CC   essential virulence determinants (Yersinia outer proteins
#=GF CC   [Yops]), which are regulated by the extracellular stimuli Ca2+
#=GF CC   and temperature. YopD is thought to be a possible transmembrane
#=GF CC   protein and contains an amphipathic alpha-helix in its carboxy
#=GF CC   terminus [1].  
#=GF SQ   10
#=GS Q7N0X4_PHOLL/1-294      AC Q7N0X4.1
#=GS D0Z4V7_PHODD/189-286    AC D0Z4V7.1
#=GS E3BLV9_9VIBR/64-332     AC E3BLV9.1
#=GS A0A4P7L304_9GAMM/1-227  AC A0A4P7L304.1
#=GS Q87P62_VIBPA/59-334     AC Q87P62.1
#=GS O68699_YERPE/7-306      AC O68699.1
#=GS T0QH28_PHOTE/1-294      AC T0QH28.1
#=GS U3AVT0_9VIBR/37-334     AC U3AVT0.1
#=GS Q9I323_PSEAE/1-295      AC Q9I323.1
#=GS D0Z4V7_PHODD/64-196     AC D0Z4V7.1
Q7N0X4_PHOLL/1-294                 .........................................MKIND.-NASSQGVTSSNGVEVGTDNFVSTPTAHEAAI--QQPEKTRLTDKVELIVPKQGLDPSRLGNVG..QE.L.NNTLDMMSLLFEIAKRMRELGILQRDTENKASIDAQKSQVDEMRHGAKLMIAMAVVSGLMTLGSGLIGSFSSVKNSQAVKQQ....KTLESNIAGRNKLIES..KLQQLG......KSSDA.....DRAAIGK.VW..NV.AQDADK..STLKSLTLVFESRNSNQQLLTSVMK...SLEGM..SNNSVQVEQGLSQAKAKEHEVGSSIAQHEKQKSEDQISLNNNFMKDVLQLLQQLYQNHVQALRAATGVV........................
D0Z4V7_PHODD/189-286               .....................................gsai-----.----------------------------------------------------------------..--.-.----------------------------------------------------------------------------------....----------------..------......-----.....-------.--..--.------..-----AANKFQKQMATNNAVNTVIQ...AIGQM..ANSAANVEQTKAQARSKEDEILATHAQASKQKADENVGFQEGLLKELRELFRSISDSQNQAWRASI---ptv.....................
E3BLV9_9VIBR/64-332                .......kqgqevsavinevrssvmqltksvlntvssepif-----.------------------------------------------------------------KSSA..DA.V.AETKSLFHLLLEITKLSREQQTRQRDIATNANVTSLKTQAAELRSSTYTMIAMAVVSGVVAGVTAAFGANNSAKASKNLKSD....MGLSNQVKMQQKAADDieKLNT-A......GISDS.....MRAQLNK.AK..AEsEKIKARidPELQINKTQSDKLSSSFAAKNSVLQ...TTGQM..SNSAVNIHQTSAQAATKDAEIIAALAQASKEKVGEGIANVDTMLNHILEIYRTYVEAMNQASRTAANV-........................
A0A4P7L304_9GAMM/1-227             .......................................mm-----.----------------------------------------------------------------..--.-.----DCIALLVKAQQQVRQSNDAVASNQATAAAESQKKQAQEMDKNSDWQLALSIVSGVLNFGMTALSAISTFKANKTQQQK....NTLQQSINERTELVKT..KTSQLKdktlsvKQKDN.....LKVEIAK.LK..DL.-NKADN..LQLKTLNDASAASQKWFDLANSALQqgsSFVDKfsSAKEIKTQQTVTQEQAKEN-----SAQQVQQKSRNETDYLNGLTTKLNQLMIQLSQGQSQALRAAT---pa......................
Q87P62_VIBPA/59-334                ...........apaisnqaqvvanlmgelaptidllmstta-----.----------------------------------------------------KVLNGEEVIKSP..SDaV.SQSLSLLTLLYQVSKLSREQQVLQREIAVEANVASLQSQAAELNNSASAMIAMAVVSGVLAGATAIIGALGSFKAGKEIKTEmasnNVLKTQKAGFDQVEE-..-LMNNG......NLSKT.....QQDQVKR.AHslAK.DSIADT.tAQLTSGGRKFDKLMSSNQAKNAILQ...ALGQM..ANSASNVEQTKAQARSKDDEVQATRAQAAKQKADENIGFQEGLLKELRELFRSISDSQNQAWRASI---ptv.....................
O68699_YERPE/7-306                 ...................................tdspii-----.TTGSQLDAITTETVKQSGEIKKTEDTRHEAQAIKSSEASLSRSQVPELIKPSQGINVALLSKSQ..GD.L.NGTLSILLLLLELARKAREMGLQQRDIENKATITAQKEQVAEMVSGAKLMIAMAVVSGIMAATSTVASAFSIAKEVKIVKQE....QILNSNIAGREQLIDT..KMQQMS......NIGDKa...vSREDIGR.IW..KP.EQVADQ..NKLALLDKEFRMTDSKANAFNAATQ...PLGQM..ANSAIQVHQGYSQAEVKEKEVNASIAANEKQKAEEAMNYNDNFMKDVLRLIEQYVSSHTHAMKAAFGVV........................
T0QH28_PHOTE/1-294                 ...................................metinn-----.-VSSHQVINVNNSVDIVTDK-SSVITTHEAAI--QLPEKAARMDKVDLITPKQGLDLSRLGNVK..QE.L.SNTLDMLSLLFEIAKKMRELGILQRDTENRATIDAQKSQVDEMRHGAKLMIAMAVVSGVMTLGSGLVGSFSAFKNSKSVKQQ....KMLENNIAGRKELVDI..KLQQKG......LSGEA.....KRAEFSQ.IW..GK.EQLADE..NTLKSLSRLFENRNSKQQLFSSVMN...SLGKM..SDNSVQVRQGLSQAKAKEYEVDASVAQHEKQKSEEQISLNNNFMKDVLQLLQQLSQSHNQAWRAAAGVV........................
U3AVT0_9VIBR/37-334                agmnqtsasarqnfyldipqvsnsalqadtavnvikaissn-----.--------------------------------------LMSLMQLKDSVMPSGIVKNSAVANEStsSS.S.ARVFDILVLLISIANLNRERQATERQVAVQRNVTSLQNQADELKHQATIQTIAAVGQGLLAVATSGLGIMSSVKSAKSLKSE....IDGNQLLKGHQTKLDQ..EMAKIR......ETKGFegakvQRAELREgVKniNT.DISNTK..IETQLSGRQFETQASKQQMIKASSD...GAGQV..MNTSVNVEQTKSQAASKEEEIDATRAQAEKQRSDDNNA-------------------------------slesliasllsifraqadsnsrlm
Q9I323_PSEAE/1-295                 .........................................MIDTQySLAATQAAIPSEPIAPGAAG-RSVGTPQAAADLPQVPAA--RADRVELNAPRQVLDPVRMEAAG..SE.L.DSSVELLLILFRIAQKARELGVLQRDNENQSIIHAQKAQVDEMRSGATLMIAMAVIAGVGALASAVVGSLGALKNGKAISQE....KTLQKNIDGRNELIDA..KMQALG......KTSDE.....DRKIVGK.VW..AA.DQVQDS..VALRAAGRAFESRNGALQVANTVIQ...SFVQM..ANASVQVRQGESQASAREGEVNATIGQSQKQKVEDQMSFDAGFMKDVLQLIQQYTQSHNQAWRAAAGVV........................
D0Z4V7_PHODD/64-196                ...................dqarvveklmsalaptvnllmq-----.-------------------------------------------------TTEKALNGEQVIKSP..SE.VvSQSLSLLTLLYQVSKLSREQQVLQREIAVEANVASLKSQAEELNNSAKAMIAMAVISGVLAGITAIVGVVGSMKAGKYIKQE....A---------------..------......-----.....-------.--..--.------..-------------------------...-----..---------------------------------------------------------------------agsaiaank...............
#=GC seq_cons                      .......................................h........................................................hsppslssttltpss..s-.l.spolslLsLLhclu+hsRE.tlhQR-htspAslsu.KsQssEhcpuAphMIAMAVVSGVhAhuoullGuhuohKsuKslKQ-....psLppplsG+ppll-t..Khpphu......p.u-t.....pRspls+.lh..sh.-phsDp..spLp.hsctF-ppsSptphhNolhQ...uhGQM..uNsulpVcQshoQApuKEpEltAohAQspKQKu--phuhpsshhK-lhpLhpphspupsQAhRAAh...........................
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