GenomeNet

Database: Pfam
Entry: cEGF
LinkDB: cEGF
Original site: cEGF 
#=GF ID   cEGF
#=GF AC   PF12662.8
#=GF DE   Complement Clr-like EGF-like
#=GF AU   Wouters M;0000-0002-2121-912X
#=GF AU   Coggill P;0000-0001-5731-1588
#=GF SE   Wouters M
#=GF GA   26.60 26.60;
#=GF TC   26.60 26.60;
#=GF NC   26.50 26.50;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 47079205 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Domain
#=GF WK   EGF-like_domain
#=GF RN   [1]
#=GF RM   15772310
#=GF RT   Evolution of distinct EGF domains with specific functions.
#=GF RA   Wouters MA, Rigoutsos I, Chu CK, Feng LL, Sparrow DB, Dunwoodie
#=GF RA   SL;
#=GF RL   Protein Sci. 2005;14:1091-1103.
#=GF DR   INTERPRO; IPR026823;
#=GF DR   SO; 0000417; polypeptide_domain;
#=GF CC   cEGF, or complement Clr-like EGF, domains have six conserved
#=GF CC   cysteine residues disulfide-bonded into the characteristic
#=GF CC   pattern 'ababcc'. They are found in blood coagulation proteins
#=GF CC   such as fibrillin, Clr and Cls, thrombomodulin, and the LDL
#=GF CC   receptor. The core fold of the EGF domain consists of two small
#=GF CC   beta-hairpins packed against each other. Two major structural
#=GF CC   variants have been identified based on the structural context of
#=GF CC   the C-terminal cysteine residue of disulfide 'c' in the
#=GF CC   C-terminal hairpin: hEGFs and cEGFs. In cEGFs the C-terminal
#=GF CC   thiol resides on the C-terminal beta-sheet, resulting in long
#=GF CC   loop-lengths between the cysteine residues of disulfide 'c',
#=GF CC   typically C[10+]XC. These longer loop-lengths may have arisen by
#=GF CC   selective cysteine loss from a four-disulfide EGF template such
#=GF CC   as laminin or integrin.  Tandem cEGF domains have five linking
#=GF CC   residues between terminal cysteines of adjacent domains. cEGF
#=GF CC   domains may or may not bind calcium in the linker region. cEGF
#=GF CC   domains with the consensus motif CXN4X[F,Y]XCXC are hydroxylated
#=GF CC   exclusively on the asparagine residue.
#=GF SQ   9725
#=GS A0A182PUQ6_9DIPT/510-533    AC A0A182PUQ6.1
#=GS A0A2Y9L1U7_ENHLU/777-798    AC A0A2Y9L1U7.1
#=GS G3NHL4_GASAC/336-360        AC G3NHL4.1
#=GS A0A498NXA1_LABRO/275-297    AC A0A498NXA1.1
#=GS W5M706_LEPOC/93-116         AC W5M706.1
#=GS A0A1S3MQS0_SALSA/2924-2947  AC A0A1S3MQS0.1
#=GS A0A3B0KSW2_DROGU/462-481    AC A0A3B0KSW2.1
#=GS B4MF28_DROVI/609-635        AC B4MF28.2
#=GS A0A2G8L911_STIJA/710-733    AC A0A2G8L911.1
#=GS M3YK40_MUSPF/1261-1284      AC M3YK40.1
#=GS A0A2K6UUZ8_SAIBB/1996-2019  AC A0A2K6UUZ8.1
#=GS A0A3B3DPN3_ORYME/138-161    AC A0A3B3DPN3.1
#=GS W5U676_ICTPU/180-203        AC W5U676.1
#=GS A0A093H9Y4_STRCA/20-42      AC A0A093H9Y4.1
#=GS A0A2U9C306_SCOMX/400-423    AC A0A2U9C306.1
#=GS A0A3P8VRM0_CYNSE/92-115     AC A0A3P8VRM0.1
#=GS A0A2K6KY92_RHIBE/273-296    AC A0A2K6KY92.1
#=GS A0A2K6QTU6_RHIRO/2962-2985  AC A0A2K6QTU6.1
#=GS A0A087YIW7_POEFO/261-284    AC A0A087YIW7.2
#=GS A0A1R3HET2_COCAP/505-523    AC A0A1R3HET2.1
#=GS A0A452QXM2_URSAM/953-976    AC A0A452QXM2.1
#=GS A0A3P8YH24_ESOLU/907-928    AC A0A3P8YH24.1
#=GS A0A3B3RR58_9TELE/679-701    AC A0A3B3RR58.1
#=GS H2ZJD3_CIOSA/939-962        AC H2ZJD3.1
#=GS G1LCY3_AILME/174-197        AC G1LCY3.1
#=GS A0A0Q9XQY0_DROMO/289-310    AC A0A0Q9XQY0.1
#=GS F7GCA1_MACMU/638-661        AC F7GCA1.2
#=GS A0A3B4THE6_SERDU/684-707    AC A0A3B4THE6.1
#=GS A0A401T2B7_CHIPU/335-358    AC A0A401T2B7.1
#=GS A0A3Q1APM2_AMPOC/373-395    AC A0A3Q1APM2.1
#=GS A0A2K5QGE4_CEBCA/460-484    AC A0A2K5QGE4.1
#=GS H2NN62_PONAB/593-616        AC H2NN62.1
#=GS A0A2K5ENE1_AOTNA/233-256    AC A0A2K5ENE1.1
#=GS F7HK13_MACMU/103-126        AC F7HK13.2
#=GS A0A2K5VLH4_MACFA/268-291    AC A0A2K5VLH4.1
#=GS A0A3B3BLH7_ORYME/443-467    AC A0A3B3BLH7.1
#=GS A0A2K5IKA5_COLAP/477-501    AC A0A2K5IKA5.1
#=GS A0A3B5B9D8_9TELE/452-475    AC A0A3B5B9D8.1
#=GS A0A2K6LX72_RHIBE/956-979    AC A0A2K6LX72.1
#=GS A0A1Q3BV48_CEPFO/500-520    AC A0A1Q3BV48.1
#=GS W4ZK98_STRPU/1457-1480      AC W4ZK98.1
#=GS A0A2D0QJZ5_ICTPU/2303-2324  AC A0A2D0QJZ5.1
#=GS A0A2K5ZZ91_MANLE/98-121     AC A0A2K5ZZ91.1
#=GS A7SSL3_NEMVE/519-542        AC A7SSL3.1
#=GS A0A1S3WAY6_ERIEU/240-263    AC A0A1S3WAY6.1
#=GS A0A2I3SZJ0_PANTR/193-216    AC A0A2I3SZJ0.1
#=GS A0A2R9C2V9_PANPA/638-661    AC A0A2R9C2V9.1
#=GS A0A212F9W8_DANPL/3106-3129  AC A0A212F9W8.1
#=GS A0A2K5CYB5_AOTNA/1996-2019  AC A0A2K5CYB5.1
#=GS A0A2K5D407_AOTNA/2561-2584  AC A0A2K5D407.1
#=GS A0A445BF67_ARAHY/521-543    AC A0A445BF67.1
#=GS A0A2K5LPD0_CERAT/733-756    AC A0A2K5LPD0.1
#=GS A0A2K6CT08_MACNE/273-296    AC A0A2K6CT08.1
#=GS A0A091XB08_OPIHO/1081-1104  AC A0A091XB08.1
#=GS A0A2U4C4X1_TURTR/127-150    AC A0A2U4C4X1.1
#=GS L5KB21_PTEAL/966-989        AC L5KB21.1
#=GS A0A3B3CDU8_ORYME/174-197    AC A0A3B3CDU8.1
#=GS A0A1X7TGV8_AMPQE/1938-1961  AC A0A1X7TGV8.1
#=GS A0A3Q1GXV1_9TELE/180-203    AC A0A3Q1GXV1.1
#=GS A0A402G440_9SAUR/19-42      AC A0A402G440.1
#=GS A0A3P8RGF2_ASTCA/188-207    AC A0A3P8RGF2.1
#=GS A0A2Y9P043_DELLE/382-404    AC A0A2Y9P043.1
#=GS A0A3B4GRR4_9CICH/3781-3802  AC A0A3B4GRR4.1
#=GS A0A3Q0R509_AMPCI/300-323    AC A0A3Q0R509.1
#=GS H3D9U0_TETNG/385-408        AC H3D9U0.1
#=GS H2XYP0_CIOIN/730-753        AC H2XYP0.1
#=GS L5JZ39_PTEAL/2192-2215      AC L5JZ39.1
#=GS A0A3B3XXL9_9TELE/368-391    AC A0A3B3XXL9.1
#=GS B1WC21_RAT/423-446          AC B1WC21.1
#=GS F1M4Q3_RAT/5452-5475        AC F1M4Q3.3
#=GS K1R9J7_CRAGI/1638-1661      AC K1R9J7.1
#=GS A0A402FQ39_9SAUR/417-440    AC A0A402FQ39.1
#=GS A0A455C8U3_PHYMC/382-404    AC A0A455C8U3.1
#=GS A0A2R8MKV1_CALJA/116-139    AC A0A2R8MKV1.1
#=GS A0A2K5VWZ5_MACFA/799-822    AC A0A2K5VWZ5.1
#=GS A0A287AH02_PIG/867-890      AC A0A287AH02.1
#=GS A0A3Q1LRZ3_BOVIN/98-121     AC A0A3Q1LRZ3.1
#=GS H3AZ49_LATCH/5257-5280      AC H3AZ49.2
#=GS A0A2Y9IKT0_ENHLU/1261-1284  AC A0A2Y9IKT0.1
#=GS A0A1D5RIC2_MACMU/274-297    AC A0A1D5RIC2.1
#=GS A0A2K6F4I1_PROCO/97-120     AC A0A2K6F4I1.1
#=GS A0A2Y9K4A1_ENHLU/92-115     AC A0A2Y9K4A1.1
#=GS A0A1D5RJ12_MACMU/940-963    AC A0A1D5RJ12.1
#=GS W9S8N8_9ROSA/503-524        AC W9S8N8.1
#=GS F7E718_ORNAN/326-349        AC F7E718.2
#=GS A7RF88_NEMVE/67-99          AC A7RF88.1
#=GS A0A0V1CK09_TRIBR/3119-3142  AC A0A0V1CK09.1
#=GS B8A4X3_DANRE/217-240        AC B8A4X3.1
#=GS A0A2K5WAB3_MACFA/756-779    AC A0A2K5WAB3.1
#=GS A7RVK3_NEMVE/192-215        AC A7RVK3.1
#=GS A0A2K6FD62_PROCO/1509-1532  AC A0A2K6FD62.1
#=GS A0A1W4X7B0_AGRPL/1491-1513  AC A0A1W4X7B0.1
#=GS W5MPB2_LEPOC/2161-2184      AC W5MPB2.1
#=GS A0A2K6DUB7_MACNE/73-96      AC A0A2K6DUB7.1
#=GS A0A2K5DTT0_AOTNA/506-530    AC A0A2K5DTT0.1
#=GS A0A1L8FML6_XENLA/295-317    AC A0A1L8FML6.1
#=GS A0A2K6UQ62_SAIBB/964-987    AC A0A2K6UQ62.1
#=GS A0A2G5U108_9PELO/544-567    AC A0A2G5U108.1
#=GS B5DR05_DROPS/700-721        AC B5DR05.2
#=GS A0A3B4YZH5_SERLL/254-277    AC A0A3B4YZH5.1
#=GS A0A2K6DQ52_MACNE/236-259    AC A0A2K6DQ52.1
#=GS W5P565_SHEEP/5407-5430      AC W5P565.1
#=GS A0A1X7STM4_AMPQE/424-447    AC A0A1X7STM4.1
#=GS A0A2U3Y938_LEPWE/183-206    AC A0A2U3Y938.1
#=GS A0A0J7L1W8_LASNI/3069-3092  AC A0A0J7L1W8.1
#=GS A0A3B4VJS5_SERDU/3973-3996  AC A0A3B4VJS5.1
#=GS A0A452QAC0_URSAM/65-88      AC A0A452QAC0.1
#=GS A0A2I2ZDD6_GORGO/423-446    AC A0A2I2ZDD6.1
#=GS Q9V4B8_DROME/721-744        AC Q9V4B8.3
#=GS G1RT74_NOMLE/477-501        AC G1RT74.2
#=GS A0A0R3U960_9CEST/412-435    AC A0A0R3U960.2
#=GS Q54YP0_DICDI/422-445        AC Q54YP0.1
#=GS A0A2U4AI28_TURTR/382-405    AC A0A2U4AI28.1
#=GS A0A3P9PJ53_POERE/367-390    AC A0A3P9PJ53.1
#=GS A0A2K6UC62_SAIBB/183-206    AC A0A2K6UC62.1
#=GS A0A182RLK5_ANOFN/710-733    AC A0A182RLK5.2
#=GS A0A3B4X2W0_SERLL/491-515    AC A0A3B4X2W0.1
#=GS A0A3Q2X5A8_HAPBU/890-913    AC A0A3Q2X5A8.1
#=GS A0A2D0SLD8_ICTPU/99-122     AC A0A2D0SLD8.1
#=GS A0A3B4U5D9_SERDU/408-431    AC A0A3B4U5D9.1
#=GS A0A3Q3XIQ4_MOLML/261-283    AC A0A3Q3XIQ4.1
#=GS A0A2K5Y247_MANLE/192-215    AC A0A2K5Y247.1
#=GS E7FDJ3_DANRE/10-33          AC E7FDJ3.3
#=GS A0A1L8HA12_XENLA/2960-2983  AC A0A1L8HA12.1
#=GS A0A1U8BW98_MESAU/593-616    AC A0A1U8BW98.1
#=GS A0A2K5IZ64_COLAP/254-277    AC A0A2K5IZ64.1
#=GS A0A151WY85_9HYME/657-680    AC A0A151WY85.1
#=GS A0A183H2X7_9BILA/350-371    AC A0A183H2X7.1
#=GS W5PSC8_SHEEP/227-250        AC W5PSC8.1
#=GS A0A3Q3E225_9LABR/334-357    AC A0A3Q3E225.1
#=GS A0A3Q1G1Z8_9TELE/254-277    AC A0A3Q1G1Z8.1
#=GS A0A2A3EIG6_APICC/2408-2431  AC A0A2A3EIG6.1
#=GS F7E702_ORNAN/337-360        AC F7E702.2
#=GS A0A3Q1BFI7_AMPOC/168-191    AC A0A3Q1BFI7.1
#=GS A0A287B5Q1_PIG/910-933      AC A0A287B5Q1.1
#=GS A0A3P8RB56_ASTCA/438-462    AC A0A3P8RB56.1
#=GS A0A0R3P5Y7_DROPS/700-721    AC A0A0R3P5Y7.1
#=GS A0A2I2YP07_GORGO/178-201    AC A0A2I2YP07.1
#=GS A0A154P0K8_DUFNO/1135-1158  AC A0A154P0K8.1
#=GS A0A0G2KAI7_RAT/73-96        AC A0A0G2KAI7.1
#=GS A0A0L0FJ31_9EUKA/444-465    AC A0A0L0FJ31.1
#=GS F7HHZ6_CALJA/1263-1286      AC F7HHZ6.2
#=GS A0A1L8G9Q2_XENLA/1446-1467  AC A0A1L8G9Q2.1
#=GS A0A0L7QUY6_9HYME/1239-1262  AC A0A0L7QUY6.1
#=GS A0A3Q2VCC0_HAPBU/254-277    AC A0A3Q2VCC0.1
#=GS B4QKV7_DROSI/623-644        AC B4QKV7.1
#=GS A0A2I4B4G3_9TELE/4017-4040  AC A0A2I4B4G3.1
#=GS A0A455C5B9_PHYMC/63-86      AC A0A455C5B9.1
#=GS A0A443QV85_9ACAR/725-748    AC A0A443QV85.1
#=GS A0A099ZTK9_TINGU/559-581    AC A0A099ZTK9.1
#=GS A0A2B4SW57_STYPI/1838-1861  AC A0A2B4SW57.1
#=GS G1LTF0_AILME/328-351        AC G1LTF0.1
#=GS A0A2G8KB66_STIJA/472-495    AC A0A2G8KB66.1
#=GS A0A2I4CN44_9TELE/1179-1202  AC A0A2I4CN44.1
#=GS A0A3P8TW60_AMPPE/542-563    AC A0A3P8TW60.1
#=GS A0A2Y9IKT0_ENHLU/1994-2017  AC A0A2Y9IKT0.1
#=GS A0A2K6NJ72_RHIRO/234-257    AC A0A2K6NJ72.1
#=GS A0A1S3BY11_CUCME/500-521    AC A0A1S3BY11.1
#=GS A0A2R9B405_PANPA/239-262    AC A0A2R9B405.1
#=GS K7CK50_PANTR/421-444        AC K7CK50.1
#=GS F6RBV6_CALJA/192-215        AC F6RBV6.2
#=GS A0A494BBF0_MOUSE/195-218    AC A0A494BBF0.1
#=GS G3Q6N6_GASAC/96-119         AC G3Q6N6.1
#=GS C3Z8P4_BRAFL/129-152        AC C3Z8P4.1
#=GS A0A369RY18_9METZ/3192-3215  AC A0A369RY18.1
#=GS A0A3L8SX10_CHLGU/826-849    AC A0A3L8SX10.1
#=GS A0A369RN78_9METZ/244-267    AC A0A369RN78.1
#=GS A0A2I3SKL2_PANTR/73-96      AC A0A2I3SKL2.1
#=GS F6XSR3_HORSE/408-431        AC F6XSR3.2
#=GS A0A452RTE1_URSAM/140-163    AC A0A452RTE1.1
#=GS A0A2C9GPM6_ANOAR/959-982    AC A0A2C9GPM6.1
#=GS A0A2K5QGD2_CEBCA/460-484    AC A0A2K5QGD2.1
#=GS A0A443RZB4_9ACAR/187-210    AC A0A443RZB4.1
#=GS C3Y568_BRAFL/215-238        AC C3Y568.1
#=GS A0A0V0TL56_9BILA/578-601    AC A0A0V0TL56.1
#=GS A0A3Q1I796_ANATE/205-228    AC A0A3Q1I796.1
#=GS I3LW66_ICTTR/1263-1286      AC I3LW66.2
#=GS A0A0Q9WBK4_DROVI/1399-1421  AC A0A0Q9WBK4.1
#=GS B4H852_DROPE/726-749        AC B4H852.1
#=GS A0A2Y9MVK7_DELLE/3315-3338  AC A0A2Y9MVK7.1
#=GS A0A2K6C2A2_MACNE/496-520    AC A0A2K6C2A2.1
#=GS E2ADR1_CAMFO/1315-1338      AC E2ADR1.1
#=GS A0A226MQT1_CALSU/392-414    AC A0A226MQT1.1
#=GS A0A2K6UL44_SAIBB/379-401    AC A0A2K6UL44.1
#=GS A0A2I3LGE2_PAPAN/841-864    AC A0A2I3LGE2.1
#=GS B4MY15_DROWI/351-375        AC B4MY15.2
#=GS A0A195BLP7_9HYME/1463-1485  AC A0A195BLP7.1
#=GS L5KLG1_PTEAL/638-661        AC L5KLG1.1
#=GS A0A3B3QHF0_9TELE/457-481    AC A0A3B3QHF0.1
#=GS U3I1Z5_ANAPP/547-569        AC U3I1Z5.2
#=GS A0A2I3HAN1_NOMLE/537-561    AC A0A2I3HAN1.1
#=GS A0A210QZ47_MIZYE/479-502    AC A0A210QZ47.1
#=GS A0A3Q7T7U6_VULVU/416-439    AC A0A3Q7T7U6.1
#=GS A0A3Q3W4E5_MOLML/342-364    AC A0A3Q3W4E5.1
#=GS A0A0G2K769_RAT/266-288      AC A0A0G2K769.1
#=GS A0A3Q1ARI4_AMPOC/174-197    AC A0A3Q1ARI4.1
#=GS A0A3Q3BII1_KRYMA/578-601    AC A0A3Q3BII1.1
#=GS A0A1X7V656_AMPQE/720-743    AC A0A1X7V656.1
#=GS G3RW79_GORGO/274-297        AC G3RW79.2
#=GS A0A0V1M9M1_9BILA/3170-3193  AC A0A0V1M9M1.1
#=GS S4RNX1_PETMA/2931-2954      AC S4RNX1.1
#=GS A0A3Q3RTF5_9TELE/1361-1385  AC A0A3Q3RTF5.1
#=GS A0A061AKL1_CAEEL/456-479    AC A0A061AKL1.1
#=GS A0A1X7VN53_AMPQE/1448-1471  AC A0A1X7VN53.1
#=GS H2U7Q2_TAKRU/460-483        AC H2U7Q2.2
#=GS A0A1D5QS42_MACMU/2818-2841  AC A0A1D5QS42.1
#=GS A0A3Q3G035_9LABR/211-234    AC A0A3Q3G035.1
#=GS A0A1V4IQE2_PATFA/2563-2586  AC A0A1V4IQE2.1
#=GS A0A0P7VGH7_SCLFO/639-661    AC A0A0P7VGH7.1
#=GS A0A452QXT9_URSAM/874-897    AC A0A452QXT9.1
#=GS A0A2K5KPC3_CERAT/97-120     AC A0A2K5KPC3.1
#=GS A0A151ZCX2_9MYCE/275-299    AC A0A151ZCX2.1
#=GS A0A3Q2GWF8_HORSE/969-992    AC A0A3Q2GWF8.1
#=GS K7GIZ8_PELSI/419-442        AC K7GIZ8.1
#=GS A0A3P8YU01_ESOLU/67-90      AC A0A3P8YU01.1
#=GS A0A2K6T9W8_SAIBB/2548-2571  AC A0A2K6T9W8.1
#=GS A0A3P8YPG0_ESOLU/943-966    AC A0A3P8YPG0.1
#=GS HMCN1_HUMAN/5452-5475       AC Q96RW7.2
#=GS A0A091E942_CORBR/210-232    AC A0A091E942.1
#=GS A0A1A6G2L0_NEOLE/93-116     AC A0A1A6G2L0.1
#=GS A0A0Q3V0E5_AMAAE/2050-2074  AC A0A0Q3V0E5.1
#=GS A0A2Y9D2K3_ANOME/723-746    AC A0A2Y9D2K3.1
#=GS W5UBK9_ICTPU/402-425        AC W5UBK9.1
#=GS H9EMK7_MACMU/2962-2985      AC H9EMK7.1
#=GS A0A3B3IL15_ORYLA/340-362    AC A0A3B3IL15.1
#=GS A0A2T7NTE1_POMCA/649-672    AC A0A2T7NTE1.1
#=GS A0A2R8ZIS8_PANPA/1009-1032  AC A0A2R8ZIS8.1
#=GS A0A3Q2G4L6_CYPVA/974-997    AC A0A3Q2G4L6.1
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#=GS A0A4D9DYV1_9SAUR/4775-4798  AC A0A4D9DYV1.1
#=GS A0A0V0YA48_TRIPS/3938-3962  AC A0A0V0YA48.1
#=GS A0A3Q7VVK7_URSAR/104-127    AC A0A3Q7VVK7.1
#=GS B4NJC7_DROWI/615-638        AC B4NJC7.2
#=GS H9GLH5_ANOCA/900-923        AC H9GLH5.2
#=GS G3WTJ9_SARHA/250-273        AC G3WTJ9.1
#=GS R7TGE4_CAPTE/25-48          AC R7TGE4.1
#=GS C3Z8P4_BRAFL/170-193        AC C3Z8P4.1
#=GS A0A0V1GYT0_9BILA/222-245    AC A0A0V1GYT0.1
#=GS FBN1_HUMAN/510-533          AC P35555.4
#=GS H2NM18_PONAB/268-291        AC H2NM18.1
#=GS FBN1_HUMAN/2547-2570        AC P35555.4
#=GS M7AUL7_CHEMY/408-430        AC M7AUL7.1
#=GS A0A3Q7UP87_URSAR/104-127    AC A0A3Q7UP87.1
#=GS A0A1S2ZFR1_ERIEU/183-206    AC A0A1S2ZFR1.1
#=GS A0A0A0AL04_CHAVO/531-554    AC A0A0A0AL04.1
#=GS A0A3B4YGD9_SERLL/2902-2925  AC A0A3B4YGD9.1
#=GS A0A384DBL5_URSMA/593-616    AC A0A384DBL5.1
#=GS A0A1U7Q9X5_MESAU/1256-1279  AC A0A1U7Q9X5.1
#=GS A0A1S3KK60_SALSA/5337-5360  AC A0A1S3KK60.1
#=GS M9MMB9_DANRE/628-651        AC M9MMB9.1
#=GS A0A060X2E5_ONCMY/312-335    AC A0A060X2E5.1
#=GS A0A2U3YYK0_LEPWE/920-943    AC A0A2U3YYK0.1
#=GS A0A3Q4HQA2_NEOBR/482-506    AC A0A3Q4HQA2.1
#=GS A0A2K5HWJ1_COLAP/1176-1199  AC A0A2K5HWJ1.1
#=GS A0A3B4TR52_SERDU/226-249    AC A0A3B4TR52.1
#=GS R7VK09_CAPTE/65-88          AC R7VK09.1
#=GS A0A3Q3AGA3_CHICK/2982-3005  AC A0A3Q3AGA3.1
#=GS A0A452QU59_URSAM/586-609    AC A0A452QU59.1
#=GS A0A2I2Z6E5_GORGO/105-128    AC A0A2I2Z6E5.1
#=GS A0A2B4S3F3_STYPI/689-710    AC A0A2B4S3F3.1
#=GS A0A1X7TA55_AMPQE/560-584    AC A0A1X7TA55.1
#=GS F7F4J4_ORNAN/1520-1543      AC F7F4J4.1
#=GS F7DEG1_MACMU/2903-2926      AC F7DEG1.2
#=GS A0A401SB99_CHIPU/380-402    AC A0A401SB99.1
#=GS A0A3Q1MA53_BOVIN/2800-2823  AC A0A3Q1MA53.1
#=GS A0A3Q3B1E8_KRYMA/390-413    AC A0A3Q3B1E8.1
#=GS A0A3Q2CBL0_CYPVA/236-260    AC A0A3Q2CBL0.1
#=GS A0A087RJQ8_APTFO/273-295    AC A0A087RJQ8.1
#=GS A0A3Q4HJD8_NEOBR/19-42      AC A0A3Q4HJD8.1
#=GS A0A1S3HG23_LINUN/436-459    AC A0A1S3HG23.1
#=GS A0A2G8K7R6_STIJA/465-488    AC A0A2G8K7R6.1
#=GS A0A2K6FD24_PROCO/638-661    AC A0A2K6FD24.1
#=GS A0A3Q1M9L6_BOVIN/572-595    AC A0A3Q1M9L6.1
#=GS A0A118K0V2_CYNCS/521-542    AC A0A118K0V2.1
#=GS A0A096NQG4_PAPAN/888-911    AC A0A096NQG4.1
#=GS Q8SYF5_DROME/140-163        AC Q8SYF5.1
#=GS A0A1X7VPQ3_AMPQE/2306-2329  AC A0A1X7VPQ3.1
#=GS A0A2K6UQF0_SAIBB/917-940    AC A0A2K6UQF0.1
#=GS H2LFW4_ORYLA/332-355        AC H2LFW4.2
#=GS H2UW69_TAKRU/347-369        AC H2UW69.2
#=GS A0A2R9C2V9_PANPA/1263-1286  AC A0A2R9C2V9.1
#=GS L9JLV5_TUPCH/250-273        AC L9JLV5.1
#=GS A0A1S3H3N0_LINUN/340-363    AC A0A1S3H3N0.1
#=GS A0A087XGS5_POEFO/197-220    AC A0A087XGS5.2
#=GS G1T4Z1_RABIT/2966-2989      AC G1T4Z1.1
#=GS A0A3P8Y5T3_ESOLU/255-278    AC A0A3P8Y5T3.1
#=GS A0A3Q7TK98_URSAR/1001-1024  AC A0A3Q7TK98.1
#=GS A0A2D0SH52_ICTPU/441-465    AC A0A2D0SH52.1
#=GS A0A091VJT9_OPIHO/20-42      AC A0A091VJT9.1
#=GS A0A3B0JY30_DROGU/376-400    AC A0A3B0JY30.1
#=GS I1L6Z9_SOYBN/497-516        AC I1L6Z9.1
#=GS A0A2K5N2I6_CERAT/638-661    AC A0A2K5N2I6.1
#=GS A0A2B4SYU3_STYPI/149-172    AC A0A2B4SYU3.1
#=GS A0A452GUV8_9SAUR/985-1008   AC A0A452GUV8.1
#=GS A0A493TF71_ANAPP/456-479    AC A0A493TF71.1
#=GS A0A3Q2LUG3_HORSE/86-109     AC A0A3Q2LUG3.1
#=GS A0A2I4CEQ4_9TELE/97-120     AC A0A2I4CEQ4.1
#=GS A0A3P8RFG2_ASTCA/286-309    AC A0A3P8RFG2.1
#=GS A0A3Q2CE00_CYPVA/91-114     AC A0A3Q2CE00.1
#=GS E9FZA9_DAPPU/3039-3062      AC E9FZA9.1
#=GS A0A3Q0QXL8_AMPCI/725-748    AC A0A3Q0QXL8.1
#=GS W5PBS4_SHEEP/2911-2934      AC W5PBS4.1
#=GS A0A452H4N8_9SAUR/94-117     AC A0A452H4N8.1
#=GS A0A2R9B5L3_PANPA/259-282    AC A0A2R9B5L3.1
#=GS A0A1S3F058_DIPOR/733-756    AC A0A1S3F058.1
#=GS F6YVP3_MACMU/545-568        AC F6YVP3.2
#=GS FBLN5_RAT/268-291           AC Q9WVH8.1
#=GS H3CVN7_TETNG/173-195        AC H3CVN7.1
#=GS W5PSC8_SHEEP/187-210        AC W5PSC8.1
#=GS W5QDP8_SHEEP/460-484        AC W5QDP8.1
#=GS A0A1D5R7Z0_MACMU/460-484    AC A0A1D5R7Z0.1
#=GS W5K0F1_ASTMX/93-116         AC W5K0F1.2
#=GS A0A452F2Z1_CAPHI/463-487    AC A0A452F2Z1.1
#=GS A0A3Q1FHB7_9TELE/165-185    AC A0A3Q1FHB7.1
#=GS A0A2I2Y2H7_GORGO/1944-1967  AC A0A2I2Y2H7.1
#=GS C3YDY8_BRAFL/21-44          AC C3YDY8.1
#=GS A0A3B1IMG7_ASTMX/93-116     AC A0A3B1IMG7.1
#=GS W5P094_SHEEP/782-803        AC W5P094.1
#=GS A0A0V0UQ30_9BILA/551-574    AC A0A0V0UQ30.1
#=GS A0A2I2YVW9_GORGO/193-216    AC A0A2I2YVW9.1
#=GS C3ZHF8_BRAFL/22-43          AC C3ZHF8.1
#=GS B4JZT0_DROGR/646-669        AC B4JZT0.1
#=GS A0A1D5RJX9_MACMU/224-247    AC A0A1D5RJX9.1
#=GS G5APM0_HETGA/776-797        AC G5APM0.1
#=GS E0VRN4_PEDHC/2391-2414      AC E0VRN4.1
#=GS A0A0R4I9I8_DANRE/1045-1068  AC A0A0R4I9I8.2
#=GS B7PIR8_IXOSC/21-44          AC B7PIR8.1
#=GS A0A099ZAJ3_TINGU/183-206    AC A0A099ZAJ3.1
#=GS A0A183LLE3_9TREM/703-726    AC A0A183LLE3.1
#=GS A0A088A1H4_APIME/2461-2484  AC A0A088A1H4.1
#=GS G1T1H4_RABIT/2550-2573      AC G1T1H4.2
#=GS A0A3B4WT31_SERLL/2914-2937  AC A0A3B4WT31.1
#=GS A0A340XDV7_LIPVE/382-404    AC A0A340XDV7.1
#=GS A0A3B3C1C5_ORYME/361-383    AC A0A3B3C1C5.1
#=GS A0A3B4V3L1_SERDU/174-197    AC A0A3B4V3L1.1
#=GS A0A2K6P9C4_RHIRO/273-296    AC A0A2K6P9C4.1
#=GS A0A3P9NW58_POERE/211-234    AC A0A3P9NW58.1
#=GS A0A2K6CJU3_MACNE/964-987    AC A0A2K6CJU3.1
#=GS A0A3P8VN17_CYNSE/98-129     AC A0A3P8VN17.1
#=GS E2BFB6_HARSA/3082-3105      AC E2BFB6.1
#=GS A0A1U7RD84_ALLSI/233-256    AC A0A1U7RD84.1
#=GS B4HV95_DROSE/405-424        AC B4HV95.1
#=GS U3J0X0_ANAPP/94-117         AC U3J0X0.2
#=GS A0A1S3SGL8_SALSA/93-116     AC A0A1S3SGL8.1
#=GS A0A3P8SHW4_AMPPE/173-196    AC A0A3P8SHW4.1
#=GS A0A2K6NJ61_RHIRO/264-287    AC A0A2K6NJ61.1
#=GS V4S6N5_9ROSI/502-523        AC V4S6N5.1
#=GS A0A2C9K9Q8_BIOGL/1316-1337  AC A0A2C9K9Q8.1
#=GS A0A2K6CJY0_MACNE/235-259    AC A0A2K6CJY0.1
#=GS A0A093G774_DRYPU/359-381    AC A0A093G774.1
#=GS A0A182RF69_ANOFN/1160-1183  AC A0A182RF69.2
#=GS A0A093HPU1_STRCA/534-557    AC A0A093HPU1.1
#=GS A0A3B0JY30_DROGU/675-696    AC A0A3B0JY30.1
#=GS A0A340X217_LIPVE/463-487    AC A0A340X217.1
#=GS A0A2I0MIP8_COLLI/3128-3151  AC A0A2I0MIP8.1
#=GS A0A3B4U4K7_SERDU/491-515    AC A0A3B4U4K7.1
#=GS A0A3Q7T385_VULVU/53-76      AC A0A3Q7T385.1
#=GS A0A0L9U3H1_PHAAN/497-516    AC A0A0L9U3H1.1
#=GS A0A1U7QPI1_MESAU/274-297    AC A0A1U7QPI1.1
#=GS A0A182WXI7_ANOQN/747-770    AC A0A182WXI7.1
#=GS A0A1W4WWI1_AGRPL/617-640    AC A0A1W4WWI1.1
#=GS A0A1X7V472_AMPQE/469-492    AC A0A1X7V472.1
#=GS G3S6M4_GORGO/90-113         AC G3S6M4.2
#=GS A0A1S3JUZ2_LINUN/298-321    AC A0A1S3JUZ2.1
#=GS F1NX60_CHICK/422-445        AC F1NX60.1
#=GS A0A2A4JLI2_HELVI/528-551    AC A0A2A4JLI2.1
#=GS W4XDC5_STRPU/729-753        AC W4XDC5.1
#=GS G3VZB4_SARHA/2938-2961      AC G3VZB4.1
#=GS A0A2I4CVQ2_9TELE/191-214    AC A0A2I4CVQ2.1
#=GS A0A3Q1EK78_9TELE/234-257    AC A0A3Q1EK78.1
#=GS V4Z6X9_TOXGV/202-225        AC V4Z6X9.1
#=GS A0A445J704_GLYSO/497-516    AC A0A445J704.1
#=GS A0A3B3YQH5_9TELE/293-315    AC A0A3B3YQH5.1
#=GS FBN3_HUMAN/1093-1116        AC Q75N90.3
#=GS A0A2I3MJN6_PAPAN/115-138    AC A0A2I3MJN6.1
#=GS A0A016T6D8_9BILA/383-406    AC A0A016T6D8.1
#=GS A0A182PMJ3_9DIPT/884-907    AC A0A182PMJ3.1
#=GS A0A2U4BVE5_TURTR/781-802    AC A0A2U4BVE5.1
#=GS A0A3Q0HF10_ALLSI/543-567    AC A0A3Q0HF10.1
#=GS H2TMY7_TAKRU/104-127        AC H2TMY7.2
#=GS A0A3Q0SXE5_AMPCI/123-146    AC A0A3Q0SXE5.1
#=GS A0A3Q1MGT6_BOVIN/107-130    AC A0A3Q1MGT6.1
#=GS C3XQV8_BRAFL/52-75          AC C3XQV8.1
#=GS A0A3B4ABD8_9GOBI/176-199    AC A0A3B4ABD8.1
#=GS A0A0V1BSD4_TRISP/3149-3172  AC A0A0V1BSD4.1
#=GS A0A060WXI2_ONCMY/89-119     AC A0A060WXI2.1
#=GS K7DKI2_PANTR/268-291        AC K7DKI2.1
#=GS A0A2K6RGH4_RHIRO/706-729    AC A0A2K6RGH4.1
#=GS A0A3Q2HGM8_HORSE/961-984    AC A0A3Q2HGM8.1
#=GS A0A2U9B232_SCOMX/1369-1392  AC A0A2U9B232.1
#=GS A0A2R9AN38_PANPA/2499-2522  AC A0A2R9AN38.1
#=GS A0A182XMS1_ANOQN/467-490    AC A0A182XMS1.1
#=GS A0A3Q7T881_VULVU/5338-5361  AC A0A3Q7T881.1
#=GS A0A2K5XGJ0_MANLE/716-739    AC A0A2K5XGJ0.1
#=GS A0A093QPA1_9PASS/876-899    AC A0A093QPA1.1
#=GS A0A218UQP1_9PASE/362-385    AC A0A218UQP1.1
#=GS F6WEY7_CIOIN/885-906        AC F6WEY7.2
#=GS A0A3M6TIX2_9CNID/1965-1988  AC A0A3M6TIX2.1
#=GS A0A3Q7X3R1_URSAR/968-991    AC A0A3Q7X3R1.1
#=GS G3W087_SARHA/927-950        AC G3W087.1
#=GS A0A1A6GMC3_NEOLE/174-197    AC A0A1A6GMC3.1
#=GS A0A2G5U0Q9_9PELO/587-610    AC A0A2G5U0Q9.1
#=GS A0A2K6RSM8_RHIRO/1923-1946  AC A0A2K6RSM8.1
#=GS A0A060XAT7_ONCMY/217-240    AC A0A060XAT7.1
#=GS A0A1D5RJX9_MACMU/184-207    AC A0A1D5RJX9.1
#=GS B3N075_DROAN/3278-3301      AC B3N075.2
#=GS A0A2U3VI54_ODORO/187-210    AC A0A2U3VI54.1
#=GS A0A151P8Z4_ALLMI/130-153    AC A0A151P8Z4.1
#=GS A0A3Q7V3Z7_URSAR/2962-2985  AC A0A3Q7V3Z7.1
#=GS A0A3Q1MEB6_BOVIN/2863-2886  AC A0A3Q1MEB6.1
#=GS T1KVR2_TETUR/45-68          AC T1KVR2.1
#=GS A0A3Q7XA24_URSAR/187-210    AC A0A3Q7XA24.1
#=GS A0A2Y9SDN9_PHYMC/733-756    AC A0A2Y9SDN9.1
#=GS HMCN2_MOUSE/4689-4712       AC A2AJ76.1
#=GS A0A3M6UM98_9CNID/988-1011   AC A0A3M6UM98.1
#=GS A0A3Q3WKC0_MOLML/7-28       AC A0A3Q3WKC0.1
#=GS A0A3P9NVY2_POERE/202-226    AC A0A3P9NVY2.1
#=GS A0A3Q3W629_MOLML/241-264    AC A0A3Q3W629.1
#=GS A0A091HXG6_CALAN/582-605    AC A0A091HXG6.1
#=GS G3TTD6_LOXAF/964-987        AC G3TTD6.1
#=GS A0A3Q4M6Y2_NEOBR/190-213    AC A0A3Q4M6Y2.1
#=GS A0A2C9JTF6_BIOGL/286-309    AC A0A2C9JTF6.1
#=GS A0A3P9P233_POERE/255-277    AC A0A3P9P233.1
#=GS A0A3B3V6C1_9TELE/229-252    AC A0A3B3V6C1.1
#=GS F1QKZ9_DANRE/356-379        AC F1QKZ9.2
#=GS A0A1U7UFJ7_TARSY/560-583    AC A0A1U7UFJ7.1
#=GS A0A151MZ61_ALLMI/769-792    AC A0A151MZ61.1
#=GS A0A2D0PJ87_ICTPU/1093-1116  AC A0A2D0PJ87.1
#=GS A0A182XMS3_ANOQN/29-54      AC A0A182XMS3.1
#=GS I3MHM1_ICTTR/957-980        AC I3MHM1.2
#=GS A0A0P7WRP4_SCLFO/504-527    AC A0A0P7WRP4.1
#=GS A0A1W4WWI1_AGRPL/2481-2504  AC A0A1W4WWI1.1
#=GS A0A0V0W5R7_9BILA/3291-3314  AC A0A0V0W5R7.1
#=GS A7SBZ1_NEMVE/648-671        AC A7SBZ1.1
#=GS A0A226NYV9_COLVI/1883-1906  AC A0A226NYV9.1
#=GS A0A2I3S0K6_PANTR/97-120     AC A0A2I3S0K6.1
#=GS A0A498LP14_LABRO/223-246    AC A0A498LP14.1
#=GS F1PRU3_CANLF/995-1018       AC F1PRU3.2
#=GS A0A0V0W5Y4_9BILA/3073-3096  AC A0A0V0W5Y4.1
#=GS E9GUT4_DAPPU/98-122         AC E9GUT4.1
#=GS H2TFW6_TAKRU/607-629        AC H2TFW6.2
#=GS A0A0V1CJM4_TRIBR/3331-3354  AC A0A0V1CJM4.1
#=GS A0A151NCY9_ALLMI/668-691    AC A0A151NCY9.1
#=GS L5JP50_PTEAL/189-212        AC L5JP50.1
#=GS A0A3Q7TGE0_VULVU/781-802    AC A0A3Q7TGE0.1
#=GS A0A158PS51_BRUPA/322-345    AC A0A158PS51.1
#=GS F6RHB6_XENTR/4909-4932      AC F6RHB6.1
#=GS A0A0V0ZSN1_9BILA/588-611    AC A0A0V0ZSN1.1
#=GS LDLR_HUMAN/335-357          AC P01130.1
#=GS LDLR_HUMAN/335-357          DR PDB; 2W2M E; 314-333;
#=GS LDLR_HUMAN/335-357          DR PDB; 1HZ8 A; 22-44;
#=GS LDLR_HUMAN/335-357          DR PDB; 3GCW E; 314-332;
#=GS LDLR_HUMAN/335-357          DR PDB; 3GCX E; 314-332;
#=GS LDLR_HUMAN/335-357          DR PDB; 2W2Q E; 314-332;
#=GS LDLR_HUMAN/335-357          DR PDB; 2W2P E; 314-332;
#=GS LDLR_HUMAN/335-357          DR PDB; 1I0U A; 22-44;
#=GS LDLR_HUMAN/335-357          DR PDB; 3P5C L; 314-336;
#=GS LDLR_HUMAN/335-357          DR PDB; 3BPS E; 314-332;
#=GS LDLR_HUMAN/335-357          DR PDB; 1N7D A; 314-336;
#=GS LDLR_HUMAN/335-357          DR PDB; 3M0C C; 314-336;
#=GS LDLR_HUMAN/335-357          DR PDB; 2W2O E; 314-332;
#=GS LDLR_HUMAN/335-357          DR PDB; 2W2N E; 314-333;
#=GS LDLR_HUMAN/335-357          DR PDB; 1XFE A; 65-83;
#=GS LDLR_HUMAN/335-357          DR PDB; 1HJ7 A; 314-336;
#=GS LDLR_HUMAN/335-357          DR PDB; 2MG9 A; 22-26;
#=GS LDLR_HUMAN/335-357          DR PDB; 4NE9 D; 22-26;
#=GS LDLR_HUMAN/335-357          DR PDB; 3P5B L; 314-336;
#=GS A0A3Q2HGH7_HORSE/2443-2466  AC A0A3Q2HGH7.1
#=GS A0A445F4H6_GLYSO/500-522    AC A0A445F4H6.1
#=GS A0A443SG62_9ACAR/2286-2309  AC A0A443SG62.1
#=GS A0A096MRY0_PAPAN/638-661    AC A0A096MRY0.1
#=GS A0A0G2KQ62_DANRE/1956-1979  AC A0A0G2KQ62.2
#=GS A0A091H3N7_9AVES/64-87      AC A0A091H3N7.1
#=GS A0A3P9BVJ3_9CICH/399-422    AC A0A3P9BVJ3.1
#=GS A0A093QSC0_9PASS/3102-3125  AC A0A093QSC0.1
#=GS A0A1S3WNP2_ERIEU/92-115     AC A0A1S3WNP2.1
#=GS A0A1S3PNC7_SALSA/2938-2961  AC A0A1S3PNC7.1
#=GS A0A2K6JXU4_RHIBE/76-99      AC A0A2K6JXU4.1
#=GS A0A1S3IJB1_LINUN/332-356    AC A0A1S3IJB1.1
#=GS U4U243_DENPD/2958-2981      AC U4U243.1
#=GS A0A0A0A0B0_CHAVO/264-287    AC A0A0A0A0B0.1
#=GS A0A2K6Q7J1_RHIRO/917-940    AC A0A2K6Q7J1.1
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#=GS A0A2K5I7M7_COLAP/63-86      AC A0A2K5I7M7.1
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#=GS G3HVY1_CRIGR/22-45          AC G3HVY1.1
#=GS H2UYF8_TAKRU/409-432        AC H2UYF8.2
#=GS A0A3Q3WEG6_MOLML/116-137    AC A0A3Q3WEG6.1
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#=GS A0A0L0C1S0_LUCCU/1351-1373  AC A0A0L0C1S0.1
#=GS B3RL37_TRIAD/323-345        AC B3RL37.1
#=GS A0A3Q2L323_HORSE/1884-1907  AC A0A3Q2L323.1
#=GS E1BE11_BOVIN/5452-5475      AC E1BE11.3
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#=GS A0A452IZX4_9SAUR/702-725    AC A0A452IZX4.1
A0A182PUQ6_9DIPT/510-533               .......................SYRC.G...............CH..PGYR.......LS............F.NN..RT........................CD...DVDE...............
A0A2Y9L1U7_ENHLU/777-798               .......................SYTC.S...............CL..PGFS.......--............G.DG..RA........................CQ...DVDE...............
G3NHL4_GASAC/336-360                   .......................SYQC.Y...............CR..RGYQ.......LS............DmDG..MT........................CE...DIDE...............
A0A498NXA1_LABRO/275-297               .......................GYSC.I...............CP..EGYQ.......LQ............R.T-..RM........................CQ...DINE...............
W5M706_LEPOC/93-116                    ......................n-YRC.T...............CY..DGFK.......LA............H.DG..HN........................CL...DVDE...............
A0A1S3MQS0_SALSA/2924-2947             .......................GYKC.K...............CW..PGFR.......LK............N.DG..QT........................CV...DIDE...............
A0A3B0KSW2_DROGU/462-481               ......................k----.-...............CN..PGFQ.......LS............P.DG..SE........................CQ...DIDE...............
B4MF28_DROVI/609-635                   .......................GYIC.A...............CP..PGHQ.......VTr..........lP.DG.vNS........................CE...DINE...............
A0A2G8L911_STIJA/710-733               .......................SFIC.T...............CR..RGYQ.......LS............Q.DR..RN........................CN...DIDE...............
M3YK40_MUSPF/1261-1284                 .......................SYEC.S...............CS..EGYA.......LM............P.DG..RS........................CA...DIDE...............
A0A2K6UUZ8_SAIBB/1996-2019             .......................SFKC.L...............CN..EGYE.......LT............P.DG..KN........................CI...DTNE...............
A0A3B3DPN3_ORYME/138-161               ......................n-YRC.T...............CY..DGFM.......LA............H.DG..HN........................CL...DVDE...............
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A0A402G440_9SAUR/19-42                 .......................SYQC.Y.......