#=GF ID ddrB-ParB
#=GF AC PF18763.1
#=GF DE ddrB-like ParB superfamily domain
#=GF AU Iyer LM;0000-0002-4844-2022
#=GF AU Aravind L;0000-0003-0771-253X
#=GF AU Burroughs AM;0000-0002-2229-8771
#=GF AU El-Gebali S;0000-0003-1378-5495
#=GF SE Iyer LM
#=GF GA 27.60 27.60;
#=GF TC 30.10 28.60;
#=GF NC 26.50 26.20;
#=GF BM hmmbuild HMM.ann SEED.ann
#=GF SM hmmsearch -Z 45638612 -E 1000 --cpu 4 HMM pfamseq
#=GF TP Family
#=GF RN [1]
#=GF RM 28559295
#=GF RT Polyvalent Proteins, a Pervasive Theme in the Intergenomic
#=GF RT Biological Conflicts of Bacteriophages and Conjugative Elements.
#=GF RA Iyer LM, Burroughs AM, Anand S, de Souza RF, Aravind L;
#=GF RL J Bacteriol. 2017; [Epub ahead of print]
#=GF DR SO; 0100021; polypeptide_conserved_region;
#=GF CC A member of the ParB/sulfiredoxin superfamily of proteins found
#=GF CC in polyvalent proteins prototyped by the version in the phage P1
#=GF CC ddRB protein. These proteins are predicted to function as
#=GF CC nucleases [1].
#=GF SQ 97
#=GS A0A1I9KFG8_9VIRU/1434-1566 AC A0A1I9KFG8.1
#=GS A0A1G9QBQ5_9FIRM/1160-1299 AC A0A1G9QBQ5.1
#=GS S2LB37_BILWA/1133-1270 AC S2LB37.1
#=GS I7HDW5_9HELI/4-123 AC I7HDW5.1
#=GS A0A1S5RFJ7_9VIRU/353-464 AC A0A1S5RFJ7.1
#=GS A0A1I3JL38_9RHOB/463-581 AC A0A1I3JL38.1
#=GS N9GEV2_ACIHA/528-658 AC N9GEV2.1
#=GS A0A100YTL1_9FIRM/1-55 AC A0A100YTL1.1
#=GS A0A1Q8ILB2_9BURK/609-789 AC A0A1Q8ILB2.1
#=GS A0A0B3RG98_9RHOB/765-883 AC A0A0B3RG98.1
#=GS A0A1S5RG15_9VIRU/1160-1271 AC A0A1S5RG15.1
#=GS A0A2H3KRW2_9CHLR/253-389 AC A0A2H3KRW2.1
#=GS A0A241VPW3_9GAMM/535-665 AC A0A241VPW3.1
#=GS R6AAX6_9BACT/1491-1625 AC R6AAX6.1
#=GS A0A1B0VFX4_9CAUD/35-168 AC A0A1B0VFX4.1
#=GS A0A084INL0_9GAMM/807-937 AC A0A084INL0.1
#=GS G9CU61_9CAUD/1219-1330 AC G9CU61.1
#=GS A0A1S5RFE0_9VIRU/1170-1281 AC A0A1S5RFE0.1
#=GS I7GUT4_9CAUD/1171-1282 AC I7GUT4.1
#=GS A0A1E8E4X6_9GAMM/1287-1413 AC A0A1E8E4X6.1
#=GS S3NHI3_9GAMM/559-689 AC S3NHI3.1
#=GS G8AQI0_AZOBR/506-634 AC G8AQI0.1
#=GS A0A1S5RH24_9VIRU/1174-1285 AC A0A1S5RH24.1
#=GS F2QAA2_HELFC/237-349 AC F2QAA2.1
#=GS A0A1S5RF61_9VIRU/1200-1311 AC A0A1S5RF61.1
#=GS A0A1S5RGW1_9VIRU/2-113 AC A0A1S5RGW1.1
#=GS A0A268U4W3_9HELI/1306-1423 AC A0A268U4W3.1
#=GS I3TGJ5_TISMK/295-421 AC I3TGJ5.1
#=GS A0A1Y1R828_9GAMM/468-601 AC A0A1Y1R828.1
#=GS A0A1S5RGY8_9VIRU/1197-1308 AC A0A1S5RGY8.1
#=GS I0ESS9_HELCM/964-1075 AC I0ESS9.1
#=GS A0A1S5RFU6_9VIRU/1182-1293 AC A0A1S5RFU6.1
#=GS A0A222YY44_9CAUD/41-174 AC A0A222YY44.1
#=GS A0A1B8J7H6_9HELI/579-690 AC A0A1B8J7H6.1
#=GS A0A1X3D9R3_9NEIS/587-712 AC A0A1X3D9R3.1
#=GS F8KP71_HELBC/291-403 AC F8KP71.1
#=GS A4JWH1_BURVG/48-231 AC A4JWH1.1
#=GS I0EUI5_HELCM/20-131 AC I0EUI5.1
#=GS A0A059KLI8_9BURK/753-887 AC A0A059KLI8.1
#=GS A0A1H2R8M2_9RHOB/468-585 AC A0A1H2R8M2.1
#=GS I7GUS8_BPKHP/1221-1332 AC I7GUS8.1
#=GS O34410_HELPY/387-498 AC O34410.1
#=GS A0A1G8LL95_9RHOB/486-604 AC A0A1G8LL95.1
#=GS F8KUC0_HELBC/3-56 AC F8KUC0.1
#=GS A0A098S5F3_9BACT/13-151 AC A0A098S5F3.1
#=GS A4WPN5_RHOS5/451-569 AC A4WPN5.1
#=GS A0A1B7GR42_9BACT/1819-1958 AC A0A1B7GR42.1
#=GS A0A0J5FWX5_9GAMM/35-168 AC A0A0J5FWX5.1
#=GS E7AAT8_HELFC/214-286 AC E7AAT8.1
#=GS I6P598_9CAUD/341-452 AC I6P598.1
#=GS A0A178GHH1_9GAMM/517-647 AC A0A178GHH1.1
#=GS V2VVX2_9GAMM/549-679 AC V2VVX2.1
#=GS I0EQK7_HELCM/1278-1389 AC I0EQK7.1
#=GS A0A1H7CX30_9RHOB/467-586 AC A0A1H7CX30.1
#=GS A0A1S5RFB0_9VIRU/1399-1510 AC A0A1S5RFB0.1
#=GS A0A099TUR1_9HELI/269-363 AC A0A099TUR1.1
#=GS A0A1S5RH15_9VIRU/1222-1333 AC A0A1S5RH15.1
#=GS A0A088EXY7_9SPHI/938-1070 AC A0A088EXY7.1
#=GS A0A1W6CZX7_9RHOB/306-432 AC A0A1W6CZX7.1
#=GS A0A1H9E173_9BURK/844-980 AC A0A1H9E173.1
#=GS A0A1S5RGN0_9VIRU/1171-1282 AC A0A1S5RGN0.1
#=GS A0A1B2LXB8_9GAMM/550-680 AC A0A1B2LXB8.1
#=GS A0A1S5RGE7_9VIRU/1172-1283 AC A0A1S5RGE7.1
#=GS A0A011PI20_9PROT/502-676 AC A0A011PI20.1
#=GS R5UWG1_9BACE/1270-1405 AC R5UWG1.1
#=GS A0A099U7K4_9HELI/337-449 AC A0A099U7K4.1
#=GS A0A031LX96_9GAMM/512-642 AC A0A031LX96.1
#=GS Q71TE6_BPP1/35-168 AC Q71TE6.1
#=GS A0A1S6IAS1_9RHOB/464-581 AC A0A1S6IAS1.1
#=GS D3NXP7_AZOS1/1-122 AC D3NXP7.1
#=GS V8CKN9_9HELI/1281-1392 AC V8CKN9.1
#=GS A5WET4_PSYWF/72-205 AC A5WET4.1
#=GS A0A1A9RVH4_9NEIS/646-771 AC A0A1A9RVH4.1
#=GS A0A0W7YQT8_9BACI/858-993 AC A0A0W7YQT8.1
#=GS A1TPS0_ACIAC/760-942 AC A1TPS0.1
#=GS A0A238HED4_9NEIS/317-440 AC A0A238HED4.1
#=GS A0A1G3JRX9_9SPHN/694-822 AC A0A1G3JRX9.1
#=GS E6V3S1_VARPE/495-628 AC E6V3S1.1
#=GS A0A1S5RG98_9VIRU/1197-1308 AC A0A1S5RG98.1
#=GS A0A1S5RGQ2_9VIRU/298-409 AC A0A1S5RGQ2.1
#=GS A0A1S5RFG7_9VIRU/1196-1307 AC A0A1S5RFG7.1
#=GS E7G4N4_9HELI/243-355 AC E7G4N4.1
#=GS A0A249PFF4_9RHIZ/310-438 AC A0A249PFF4.1
#=GS A0A1S5RF23_9VIRU/1186-1297 AC A0A1S5RF23.1
#=GS A0A1G3JKH8_9SPHN/870-993 AC A0A1G3JKH8.1
#=GS F8KQN1_HELBC/463-575 AC F8KQN1.1
#=GS A0A1S5RFV6_9VIRU/1174-1285 AC A0A1S5RFV6.1
#=GS A0A1S9ZUA0_MORBO/586-710 AC A0A1S9ZUA0.1
#=GS A0A0Q7Z659_9SPHN/546-663 AC A0A0Q7Z659.1
#=GS A5WEY6_PSYWF/72-205 AC A5WEY6.1
#=GS A0A1V0M4M1_9GAMM/35-168 AC A0A1V0M4M1.1
#=GS A0A268TWB6_9HELI/709-827 AC A0A268TWB6.1
#=GS E1GWG1_9BACT/1274-1410 AC E1GWG1.1
#=GS A0A1L3ZY23_9SPHN/394-511 AC A0A1L3ZY23.1
#=GS A0A1S5RG62_9VIRU/1183-1294 AC A0A1S5RG62.1
#=GS A0A099U6B5_9HELI/315-427 AC A0A099U6B5.1
#=GS A0A1N6K1P7_9BURK/575-751 AC A0A1N6K1P7.1
A0A1I9KFG8_9VIRU/1434-1566 ......................p-KGQSVEVQY.RVMEAADLVASHDfegnl.......nhdypQQLQPRDR...SKQ.TYRVQVGQIAAAPDGARLAASPET.DRGAPIV.........................................................-.RDG..IVESGNGRTIGLKQA...YQRG......DAGAYRAYLLTHATEFGLDAAAIEAMSAPVLVRER-l......
A0A1G9QBQ5_9FIRM/1160-1299 .....................tl--DKGFNATY.KLVPSGDLITSNLtdysi.......npkypIELQPRDR...QRG.EMRNQVEKMARTIKPELLSDSQFV.NQGAPVV.........................................................N.KNG..IVLNGNGRTIAIQRA...YEGQdrqhkiSAAGYKQYLKDNANKFGFTSGQVQAIDNPILVRQV-d......
S2LB37_BILWA/1133-1270 ....................pnr---ADEPAHY.ELLEADDVRASHLpsrgfq.....knpaygLENERRYH...DEP.GSRAKVMENAAKLDPAFLMESVDA.NHGAPVI.........................................................D.HDN..NVLGGNGRAMSIARA...YESFp....eRGEQYREALKANADRLGIDPAQVDAMHSPMLVRRL-e......
I7HDW5_9HELI/4-123 ......................d-ETAPFEAEF.AVVKLSDIKPNFD.................-NSNTQGR...-LI.KQESAIANIVNDFKPELIFYQEGG.VNGVPII.........................................................T.RDG..KVVSRNHRSEALRQI...FNAQthnaetAQQKYKQGAKEFLG--------VALENDEIIVRRL-k......
A0A1S5RFJ7_9VIRU/353-464 ......................n-EREIYDLDY.AIVKAKDLKPSFT.................-TGGTQKR...-TD.MNEEQIKSIAQNFDPKKIFGSGG-.FEDLPII.........................................................L.HDG..QVIAGNHRIAGMLNF...TPK-......SRYIYHRAIKEYYN--------IDLKPDELLVRVP-h......
A0A1I3JL38_9RHOB/463-581 ......................p-EGMRVPVTY.EVVDFDSLILASG.................-NRQNRDR...SRP.APTAEVIRRAANLDPALLMPDPKA.GYGAPIV.........................................................G.PDD..VIDSGNGRTMSIIYA...ARN-......VRDRYDAYVDAIRG-AGFE--IPEGVTSPILVARR-g......
N9GEV2_ACIHA/528-658 ......................m-DGSSYDVAY.EVRSLDELIASNDaaygv.......nplypAELQPRDR...TRE.ASRQQIENMANDLRPELLGESNML.SNGAPII.........................................................G.MDN..IVESGNGRTLAIGKA...YSEG......KADAYRQFVSDFANNRGMD---ITGINNPVLVRTR-l......
A0A100YTL1_9FIRM/1-55 ......................m----------.-------------.................--------...---.------------------------.-------.........................................................-.---..---NGNGRTMALKSV...YKGKp....kQIKAYKDFLKQNAKSLGINPATIDGVKNPVLVRQV-a......
A0A1Q8ILB2_9BURK/609-789 asttpdapavsapeapqsplpdt----------.-------------.................AVLQNRDR...STA.AAIQQMNRIAADPDPSRLSFSRDF.ANGAPVVeanpaldipadqlgredisvaadgrrip.vqyavvdagtllpsnradgtpvagyaqgH.ADR.lRAIAGNGRVAGIQAA...YERG......TTSAYRAGIAQDAPLTGIRPDVVQRMHRPVLVRIM-p......
A0A0B3RG98_9RHOB/765-883 ......................g-DGMTVDVAY.QVVDLAKLKRASG.................-ELQPRDR...TRA.ASDEQIAELAARLDPARLMPSPEA.DRGAPIV.........................................................G.GDD..VIESGNGRVMALERA...YDQHp....dRASAYRQQIETA----GFD--IPADVDRPVLIARR-t......
A0A1S5RG15_9VIRU/1160-1271 .......................NDDEIHPLKF.VIVNKSDLKPNFK.................-NTGTQTR...-TA.VDSKKVEEIAERFDPKLIIGRGG-.FDDLPII.........................................................L.KDG..QVIAGNHRTQGMLNF...NAG-......SRKKYEQAIKENFN--------IELKPDELLVRMP-k......
A0A2H3KRW2_9CHLR/253-389 ....................dps---RIYEFRY.RVVSLDELITSNTdsgsi.......npeydRALQPRQR...DRA.ASRRQVEHAAKNLVPEALIWDFKAlDKGAPII.........................................................G.SDR..QVESGNGRTMALRRA...RMEHa....dKWAAYQETLRANLLAVGLSESDLAGVESPVLVRER-i......
A0A241VPW3_9GAMM/535-665 ......................l-DGSSYDVAY.EVKSLDELIASNDtaygv.......nlnypGELQPRDR...TRE.ASRQQIENIANDLRPEWLMESHKL.QDGAPII.........................................................G.MDN..VVESGNGRTLAITKA...YESG......NGENYRKHIEDYAREKGWD---ISGINKPVLVRTR-l......
R6AAX6_9BACT/1491-1625 ......................a-DGSTIRGHY.VLTEAGAATASHDvnnayeptegfpvdengESVNDRDY...KRDrDAQRIVQDIADNYDSRALQ-SPV-.-----IV.........................................................S.KDG..VVLSGNNRTMSGEIA...AKNG......TDKAYVDHLREFGAMFGFTPEQIEGMQHPRVV----fvpd...
A0A1B0VFX4_9CAUD/35-168 ......................a-KGDEVKTAF.DIVDASALLVSNTldgki.......npdypQELQPRDR...TRA.SSLLQVNQISKDLRPAQLTDSGLS.SHGAPII.........................................................G.EDN..AVESGNGRTMGIIKA...YQDG......NADRYREYLIEHATEFGIRPEKVESMTAPVLVRRR-l......
A0A084INL0_9GAMM/807-937 .....................gr--GDKVDVQG.EFVDANDLVASHTaqgnv.......npsfpESLQPRDR...SRV.SSQAQIGHMARNLDPELLDDTAKA.SDGAPIV.........................................................G.PDN..VVESGNGRVNAIRHA...YAAG......NADAYRKFVERKAQRAGVD---LSGMDNPVYVRRR-t......
G9CU61_9CAUD/1219-1330 ......................n-EREIYDLDY.AIVKAKDLTPSFS.................-TGGTQKR...-TD.MNEEQIKSIAQNFDPKKIFGSGG-.FEDLPII.........................................................L.HDG..QVIAGNHRIAGMLNF...TPK-......SRYIYERAIKEYYQ--------IDLKPDELLVRVP-h......
A0A1S5RFE0_9VIRU/1170-1281 ......................n-DDEIHSLKF.VIVNKSDLKPNFK.................-NTGTQTR...-TA.VDSKKVEEIAKRFDPKLIIGRGG-.FDDLPIV.........................................................L.PDG..QVIAGNHRIQGMLNF...NAE-......SRKKYEQALKENFN--------IKLKPNELLVRMP-e......
I7GUT4_9CAUD/1171-1282 ......................n-EREIYDLNY.AIVKAKDLKPSFT.................-TGGTQKR...-TD.MNEEQIKSIAENFDPKKIFGSGG-.FEDLPII.........................................................L.HDG..QVIAGNHRVAGMLNF...TPK-......SRFAYERAIKEYYH--------IDLKPDELLVRLP-s......
A0A1E8E4X6_9GAMM/1287-1413 .....................pa--GREFKVRH.KVVEADDLITSNLdsgai.......nseypQALQPRDR...TTL.KSITQVNDIANKLNPKLLGDSASS.TNGAPIV.........................................................S.PGN..EVESGNGRTLAIRKA...YQTG......KADAYKDWLQDQ----GYD---VANMQQPVLVRER-i......
S3NHI3_9GAMM/559-689 ......................m-DGSSYDVMP.EIRSIDDLIASNDsafgv.......npdypADLQPRDR...TRA.ANSEQIEVMANNLRPELLSDSPKI.SDGSPIL.........................................................G.SDG..VVESGNGRTMAIRRA...YETG......KADDYKAFVQQYAADRGWD---ISGIKNPVLVRNR-l......
G8AQI0_AZOBR/506-634 .....................ps--GRPVDVEY.RAVEAESLIASHDaqggv.......npqfpAELQPRDR...TRI.ASQAQIAGIAANLQPERLGRSPDA.ATGAPIV.........................................................G.PDN..VVESGNGRVGAIRRA...YEQGg....eAADRYRSWAVQQDP-------AAAQMRNPVLVAVR-r......
A0A1S5RH24_9VIRU/1174-1285 ......................n-EREIYDLDY.AIVKAKDLKPSFT.................-TGGTQKR...-TD.MNEEQIKSIAENFDPKKIFGSGG-.FEDLPII.........................................................L.HDG..QVIAGNHRIQGMLNF...TPK-......SRFAYERAIKEYYH--------IDLKPDELLVRVP-h......
F2QAA2_HELFC/237-349 ......................d-DDHIYPLDF.VVVKAKDIKPSFN.................TGVGTQTR...-TQ.TNSKMVEQIAQNFKPEMVLNRGG-.FDDLPLI.........................................................L.SDG..QVIAGNHRAKGMQNF...TPQ-......SRHTYEQAILEHYG--------LELKGDELLMRT--pk.....
A0A1S5RF61_9VIRU/1200-1311 ......................n-EREIYDLDY.AIVKAKDLKPSFT.................-TGGTQKR...-TD.MNEEQIKSIAENFDPKKIFGSGG-.FEDLPII.........................................................L.HDG..QVIAGNHRIQGMLNF...TPK-......SRYIYEKAIQEYYN--------IDLKPDELLVRVP-h......
A0A1S5RGW1_9VIRU/2-113 ......................n-EREIYDLDY.AIVKAKDLKPSFT.................-TGGTQKR...-TD.MNEEQIKSISNNFDPKKIFGSGG-.FEDLPII.........................................................L.HDG..QVIAGNHRIQGMLNF...TPK-......SRFAYEKAIKEYYH--------IDLKPDELLVRVP-h......
A0A268U4W3_9HELI/1306-1423 .....................np--KRKIDIVY.KVIEAKDLKPNFI.................GGSGMQYR...-YA.DNQNAITKIVDDFDADIHFGKEGG.FDGVPIV.........................................................D.YRG..NILAGNHRSQAILNL...YKHN......KQKPYIEGIEEYYD-----KDILKGFKQPLIVRVL-e......
I3TGJ5_TISMK/295-421 ......................s-EQRRIQTRY.EVVEADSLVTSNLadgti.......npafpADLQPRQR...DRM.ASREQISAMAADLQPARLGASADA.ATGAPVV.........................................................S.AEG..VVESGNGRVLAIREA...YARG......LDADYRAFLARE----GYQ---IEGMTAPVLVRRR-v......
A0A1Y1R828_9GAMM/468-601 .....................ir--GTGVDVDY.AVVDADDLITSHGpngvt.......npeypVSLQPRDR...SRG.SSEAQIRQMAANLRPEWMGASPKA.SDGAPII.........................................................G.ADR..VVESGNGRVAAIRYS...YDGG......DTAGYRQWLRDNAEAYGLDKDVVSGMDKPVLVRVRK.......
A0A1S5RGY8_9VIRU/1197-1308 ......................n-EREIYDLDY.AIVKAKDLKPSFI.................-TGGTQKR...-TD.MNEEQIKSIAENFDPKKIFGSGG-.FEDSPII.........................................................L.HDG..QVIAGNHRIQGMLNF...TPK-......SRFAYEKAIKEYYH--------IDLKPDELLVRVP-h......
I0ESS9_HELCM/964-1075 .......................NDGEIFDLDY.AIVKAKDLKPSFT.................-TGGTQKR...-TH.MNEEQIKNIAENFDPQKIFGSGG-.FEDLPII.........................................................L.QDG..QVISGNHRIQGMLNF...TNK-......SRAAYDKAIQDYYN--------ITLKPDELLIRVP-h......
A0A1S5RFU6_9VIRU/1182-1293 ......................n-EREIYDLNH.AIVKAKDLKPSFT.................-TGGTQKR...-TD.MNEEQIKSIAENFDPKKIFGSGG-.FEDLPII.........................................................L.HDG..QVIAGNHRIQGMLNF...TPK-......SRFTYNKAIKEYYH--------IDLKPDELLVRLP-s......
A0A222YY44_9CAUD/41-174 ......................s-KGAEVKTAF.KVVDASSLIISNNldgti.......npafpEELQPRDR...TRL.SSKLQVNRIASDLRPAQLMDSGMS.SHGAPIV.........................................................G.PDN..VVESGNGRSMGIWRA...YEQG......QADEYRQYLIDHAKEFGLNPDEISQMSMPVLVRER-l......
A0A1B8J7H6_9HELI/579-690 ......................n-ENEIYPLDF.VIVKKQDLKPNFN.................-ASELQGR...-TE.ANTHTIQDIANNFNPQKILGRGG-.FQDLPII.........................................................R.KDG..AIISGNHRTQGMLEF...SQE-......SRAAYENAIKEQYG--------ITLKDDELLMRTP-k......
A0A1X3D9R3_9NEIS/587-712 ......................l-DGKMQDATL.ELMDADELTPAVA................nTDNQYRDR...SRA.ASQVQINQIANNLEPELLGDSKQI.DSGAPTL.........................................................A.ADG.qTIIGGNGRVMAINQA...YEQG......NGDNYRQYLVDNAEQFGLNPDDIAGMNKPILVRR--fv.....
F8KP71_HELBC/291-403 ......................d-DARIYPLDF.VIVKTSDVKPNLN.................AGVGTQTR...-TQ.TNPQRIEEIAKDFKPTMVFNRGG-.FDDLPII.........................................................L.ADG..QVIAGNHRAKGMQSF...SPQ-......SREAYERAVLEHYN--------ITLKSDELLLRTP-k......
A4JWH1_BURVG/48-231 ......................a-DDALAELQA.AETLMALLKRLMTpa.............rgVILQNRDR...STP.AMIAQMNAIASAPDYYRVAPTKEF.ASGTPIVfgngdllpskiafgrndkavaadgrrfv.vqyavveaddlltsnaadgianadytngV.PGK.lRAIAGNGRLAGLKAA...YQRS......TTDDYRVELAQD-DMTGLAPGALDAFTAPILVRVM-r......
I0EUI5_HELCM/20-131 .......................NDGEIFDLDY.AIVKAKDLKPSFT.................-TGGTQKR...-TH.MNEEQIKNIAENFDPQKIFGSGG-.FEDLPII.........................................................L.QDG..QVISGNHRIQGMLNF...TNK-......SRAAYDKAIQDYYN--------ITLKPDELLIRVP-h......
A0A059KLI8_9BURK/753-887 ......................a-KGTQVLTGY.SVIEADRLITSHDpatgd......atpafpAELQPRDR...GRD.ASIAWVRKTAQDLDPDLLGKSRRA.DSGAPIV.........................................................G.PDG..VVESGNGRTMAIVLA...YQAG......KAGEYRAWLEEEAASFGLPAERVKAMKRPVLVRIR-t......
A0A1H2R8M2_9RHOB/468-585 ......................p-AGTRVQVEY.EVVDMDTLTLASG.................-DRQPRDR...SRL.APTAKVKERAAALDPALLMPSPLA.SHGAPVV.........................................................G.ADH..VIDSGNGRVMSLMHA...ADQ-......FPDRYAAYVETIRASFDV----PEGMARPVLIARR-r......
I7GUS8_BPKHP/1221-1332 ......................n-EREIYDLNY.AIVKAKDLKPSFS.................-TGGTQKR...-TD.MNEEQIKSIAQNFDPKKIFGSGG-.FEDLPII.........................................................L.HDG..QVIAGNHRVQGMLNF...TPK-......SRFAYERAIKEYYH--------IDLKPDELLVRVP-s......
O34410_HELPY/387-498 ......................n-EREIYDLDY.AIVKAKDLKPSFT.................-TGGTQKR...-TD.MNEEQIKSIAENFDPKKIFGSGG-.FEDLPII.........................................................L.HDG..QVIAGNHRIQGMLNF...TPK-......SRFSYERAIKEYYH--------IDLKPDELLVRVP-h......
A0A1G8LL95_9RHOB/486-604 ......................g-DGFRIDVEY.QVVDLASLQRASG.................-DLQPRDR...SRA.SSDEQISAIAAGLDPARLMPSPEA.DRGAPIV.........................................................G.PDS..MVESGNGRVAAIDRA...YNLHp....dRADAYRQQIIAA----GFE--IPEGMQRPVLIGRR-t......
F8KUC0_HELBC/3-56 ......................c----------.-------------.................--------...---.------------------------.----PIX.........................................................L.ADG..QVIAGNHRAKGMQSF...SPQ-......SREAYEKAVLEHYN--------IKLQSDELLLRTP-k......
A0A098S5F3_9BACT/13-151 ......................p-NGEKRDARF.AIVELDSVLASHNeltfapt...pgypvneQRQNVNDRnyeDDA.AAQERVRDNARRLDPYRLLTTSRT.PSGSPIVag.....................................................qqI.DGK.wIVVSGNNRTMSTKLA...ASRHp....eNYKAYVDALCEELEAFGFST----------------tgkteri
A4WPN5_RHOS5/451-569 ....................gda---FRIDVGY.EVVELSSLSRATG.................-GLQPRDR...SRV.ASDAWIADTAARLDPAQLMPSPTA.DRGAPIV.........................................................G.PDG..VIESGNGRTAAIARA...YERHp....dRALAYRQQIEAA----GFQ--IPAGMRQPVLIARR-q......
A0A1B7GR42_9BACT/1819-1958 .............kgreywvinl----------.-VIDAATANTSHDasgav.......negypPELQPRNR...ADR.FYRQQQARIAGRPNLDEESKTGSP.DSGPPVM.........................................................AvVDGraVTVIGNGRANAKALM...YAEPdf..aeAAAGYPAAVEGVAARRGIGAEGVRAAARPTLARL--iv.....
A0A0J5FWX5_9GAMM/35-168 ......................v-KGDKVKTAF.DVMEASDLILSNHldgri.......neaypQELQPRDR...TRL.SSKLQVNTIAKSLQPEQLADSDLS.SDGAPII.........................................................G.NDN..IVESGNGRSMGIVKA...YASG......NADDYKDYLIENANTYGLSRALIAEMERPVLVRVR-l......
E7AAT8_HELFC/214-286 ......................d-DERIYPLDF.VIVKAQDVKPSFN.................TGVGTQQR...-TQ.TNSKVVEQIAQNFKPEMVLNRGGF.-------.........................................................-.-DD..LVIAGNHRAKG----...----......------------------------------------gck....
I6P598_9CAUD/341-452 ......................n-EREIYDLNY.AIVKAKDLKPSLT.................-TGGTQKR...-TD.MNEKQIKSIAQNFDPKKIFGSGG-.FEDLPII.........................................................L.HDG..QVIAGNHRIQGMLNF...TPK-......SRFAYERAIKEYYH--------IDLKPDELLVRLP-s......
A0A178GHH1_9GAMM/517-647 ......................m-DGSSYDMAY.EVKSLDELIASNDlaygv.......nplypSELQPRDR...TRE.ASRQQIERMAEDLRPELLGESPKL.SDGAPII.........................................................G.MDN..VVESGNGRTLAIAKA...YESG......RAEEYRAFLEQYAAERGID---IAGINNPVLVRTR-l......
V2VVX2_9GAMM/549-679 ......................m-DGSSYDMQY.EIKSLDELIASNDrmygv.......nsaypQELQPRDR...TRA.ASIQQIQDMADNLRPELLGESHKL.SDGAPII.........................................................G.HDN..VVESGNGRTLAITKA...YENG......RAEEYRKYIENYAKEKGWD---ISGINNPVLVRKR-l......
I0EQK7_HELCM/1278-1389 .......................NDGEIFDLDY.AIVKAKDLKPSFT.................-TGGTQKR...-TH.MNEEQIKNIAENFDPQKIFGSGG-.FEDLPII.........................................................L.QDG..QVISGNHRIQGMLNF...TNK-......SRAAYDKAIQDYYN--------ITLKPDELLIRVP-h......
A0A1H7CX30_9RHOB/467-586 ......................g-DDIRVDVEY.EVVDISALRQATG.................-DLQPRDR...GRG.ASDVWVSDTAARLDPAQLLDSPWA.DRGAPLV.........................................................G.PDN..IIESGNGRVRAIERA...YDQVp....dRADAYRQAIEQRTG---RP--IPPEIERPVMIARR-t......
A0A1S5RFB0_9VIRU/1399-1510 ......................n-EREIYDLDY.AIVKAKDLKPSFT.................-TGGTQKR...-TD.MNEEQIKSIAENFDPKKIFGSGG-.FEDLPII.........................................................L.HDG..QVIAGNHRIQGMLNF...TPK-......SRFAYEKAIKEYYH--------IDLKPDELLVRVP-h......
A0A099TUR1_9HELI/269-363 .....................mp---KSYKAQY.VVVKTQDIKPIFS.................SQTQYQFR...-SL.YQSKKIEDIINNFDSSKMIYSEGS.FAGLPLM.........................................................D.SQG..YLLLGNHRAKALQNL...SPN-......ARSKYKQAIK--------------------------.......
A0A1S5RH15_9VIRU/1222-1333 ......................n-EREIYDLDY.AIVKAKDLKPSFT.................-TGGTQKR...-TD.MNEEQIKSIAQNFDPKKIFGSGG-.FEDLPII.........................................................L.HDG..QVIAGNHRVQGMLNF...TPK-......SRYSYDKAIKEYYN--------IDLKPDELLVRVP-h......
A0A088EXY7_9SPHI/938-1070 ......................a-DGVDVDFDY.VLVDANQLQPAHSngvrn.......hnhfvPEAQPKNR...KDA.ASLKSSDEMAAKINVRELGDNTNA.YSGAPVI.........................................................N.ERG..EVIQGNNRSDAIRKH...YES-......GRDKYKSALESNAEQFGLTKEQVQGLDKPVLVRRV-k......
A0A1W6CZX7_9RHOB/306-432 ......................a-RGREIAVEY.ALVELDDLTASQLddgrd.......npafpQELQPRDR...SGN.RSQEQIRKIAADIRPELLGENPQA.SAGAPIA.........................................................T.KGG..VVISGNGRTLALRRA...YAEG......TADGYRAWLKSQ----GYP---EGGFKRPVLVRTI-n......
A0A1H9E173_9BURK/844-980 ...................esgv----KLDGVY.ALMSADDLITSHIegswp.......nplypQELQPRDR...SRR.ASELQVSGIVQKLDPARLGASADA.ATGAPIV.........................................................G.ADG..LVESGNARMIALKRV...YHQAn...gqKAENYKAFLRDKAAQFGIDPATVDVTPKPVLVRVRS.......
A0A1S5RGN0_9VIRU/1171-1282 ......................n-EREIYDLDY.AIVKAKDLKPSFT.................-TGGTQKR...-TD.MNEEQIKSIAENFDPKKIFGSGG-.FEDLPII.........................................................L.HDG..QVIAGNHRIAGMLNF...TPK-......SRYIYNRAIKEYYH--------IDLKPDELLVRVP-n......
A0A1B2LXB8_9GAMM/550-680 ......................m-DGSSYDMSY.DVKSLDDLIASNDaafgv.......npnypAELQPRDR...TRA.ASREQIEAMANDLKPELLGESYKL.SDGAPIL.........................................................G.PDN..VVESGNGRTLALRRA...YETG......KADEYRSYIEQYAREKGWD---ISGIKNPVLVRNR-l......
A0A1S5RGE7_9VIRU/1172-1283 ......................n-EREIYDLDY.AIVKAKDLKPSFT.................-TGGTQKR...-TD.MNEEQIKSIAENFDPKKIFGSGG-.FEDLPII.........................................................L.HDG..QVIAGNHRIAGMLNF...TPK-......SRFAYEKAIQEYYH--------IDLQPDELLVRVP-h......
A0A011PI20_9PROT/502-676 ............apntgtqpape----------.-------PTGQDV.................-NLQNRDR...SRA.ASVIQMSEIARNPDYMRLGPSRTP.DSGAPMVfavgddlsripatsfgngdvavmsdgqrvpfryavvdasqvepsnfadgrvnpafaaG.QTG.tIKALNNGRTAGLRAA...YELG......SAGTYQTELAKDLANVGISPGALQATPNPILVRVY-s......
R5UWG1_9BACE/1270-1405 ...................sndv----VVPGNV.TVIDASLLQPSHIqgvrn.......slhfiDEAQPKER...NDE.ASVLSARKIAENIRPEEITSSITA.YTGAPTV.........................................................N.ERG..EVIQGNNRSDALRLM...WESHs....eQAEAYRQYLKDHAEEFGLRAEDIAPIQSPVLVNML-h......
A0A099U7K4_9HELI/337-449 ......................s-DKQIIPLDF.IKVKAEDVKPNFN.................TQSGTQTR...-AV.VDESLVDKIAQSFNPSLIFSRGG-.FDDLPII.........................................................L.KDG..QVLSGNHRVAGMQKF...NAN-......SQRLYKEGIKEHYG--------VDLADGELLLRT--pk.....
A0A031LX96_9GAMM/512-642 ......................m-DGSSYDFAY.EVKSLDELIASNDlaygv.......npnypSELQPRDR...TRE.ASRQQIEQMANDLKPEWLGESPKL.SDGAPII.........................................................G.MDN..VVESGNGRTLAIAKA...YESG......KADAYQQFVADYATSKGID---ITGINKPVLVRTR-l......
Q71TE6_BPP1/35-168 ......................a-KGDEVKTAF.DIVDASALLVSNTldgki.......npdypQELQPRDR...TRA.SSLLQVNQISKDLRPAQLTDSGLS.SHGAPII.........................................................G.EDN..AVESGNGRTMGIIKA...YQDG......NADRYREYLIDHATEFGIPPEKVESMTAPVLVRRR-l......
A0A1S6IAS1_9RHOB/464-581 ......................p-AGTRVPVEW.KIVDMADLKAASG.................-DLQPRDR...SRA.ASDAQIGEIAARLDPQRLMPSRES.DRGAPIV.........................................................G.PDM..VVESGNGRVAGLRQA...MGQ-......NPEAYAAYVDQIK---GVA-DVPKGVKNPVLVGVRK.......
D3NXP7_AZOS1/1-122 ......................m-------VRY.ELAEAGGLVTSHNadlsv.......nsafpAELQPRER...DRV.ASHEQIRSIAAGLEPERLGVSMDA.ATGAPVI.........................................................G.-GN..VVESGNGRVLALRRA...YAEHp....eAATRYRAFLTDL----GFN---PSGFREPVLVRRR-l......
V8CKN9_9HELI/1281-1392 ......................s-DDEIIPLDL.VVVKASDIEPNFY.................-ASEFQPR...-TS.KNTQVIEAIAKNFNPELVLGRGG-.YKDLPII.........................................................N.KEG..KVIIGNHRVQGFKDF...SQE-......SRQAYESAIKDRYG--------IELAPDELLLRI--ps.....
A5WET4_PSYWF/72-205 ......................a-KGTRVSTIL.AITEIDNVIASHTasgsq.......npiypQDLQPRDR...GRD.SSIAWVQKISRDLDPESLGRSGRA.DSGAPIV.........................................................G.DDM..AVESGNGRAMAIAMA...YENG......DADDYKQWLIDEADYFGFDSKGVEVFKRPILIRIR-t......
A0A1A9RVH4_9NEIS/646-771 .....................ld--NQMRQARL.QLMEADELTPSVA................gTDNQYRDR...SRA.ASQMQINHIAQNLEPELLGDSKEV.GTGAPTL.........................................................A.NDG.rTIIGGNGRVMGLAQA...YDNG......NGEGYRQYLLDHADEFGLSREEIARMNKPVLVRQL-d......
A0A0W7YQT8_9BACI/858-993 .....................ea--GTEIKFRY.EVIDAKQLIASHDtalrt.......npdypAELQPRDR...SRQ.ASKQQVTTMAQKLNPELVVESAKA.SDGAPIV.........................................................S.EDY..TVESGNGRAIAMQKM...YQENy....dTANDYKSYLESHAEKYGLDKASIEQMEQPVLVRVR-t......
A1TPS0_ACIAC/760-942 .....................qn-EWAAVKTKR.AGTNPEGTGAVGAa...............tPEIQNRDR...ARP.ASVVQMQGMAQSPDYMRLGPSRSP.ETGAPMVfavgdqvhaahaigrgdtavmsdgqrv..pfqyavmeagdvqpsnfadggvnplfdaA.HPG.tVKALNNGRTAGLRAA...YERG......TADSYRQELMADSAMHGIDPQVIAGMRAPMLVRLY-s......
A0A238HED4_9NEIS/317-440 ...................gqye------NTDW.ELREADDLGATIG................kADNQFRDR...TRQ.GSEQQVKAIADNLDYRKLGDSPMM.DYGAPTL.........................................................A.NDG.dTVIGGNGRVAAIKQA...YKQG......SAENYRAALAQDASKYGFTPEQVGQFKQPVLVRRL-q......
A0A1G3JRX9_9SPHN/694-822 ......................a-RDRDVKVRY.GVVEARDLVASNTpdgrv.......npaypAEMQPRDR...TRA.SSQMQIQQISSKLRPYWLGRTFRP.DDGAPVI.........................................................S.PEG..VVESGNGRTIAIQQV...YQQGg....pQADAYRRFVETQ----GID---TTGMEQPVLVRLR-t......
E6V3S1_VARPE/495-628 ......................e-RGMRVPFRY.RLAEADRLVTSNDadlrp.......naaypAELQPRDR...TRD.ASEAQIARIAGNLQPELLAESARA.SDGAPII.........................................................G.LDG..VVESGNGRMLALGRA...YGGE......RGAEYRAWLEGNAERFGLDAADVRTMQRPVLVRER-i......
A0A1S5RG98_9VIRU/1197-1308 ......................n-EREIYDLDY.AIVKAKDLKPSFT.................-TGGTQKR...-TD.MNEEQIKSIAENFDPKKIFGSGG-.FEDLPII.........................................................L.HDG..QVIAGNHRIQGMLNF...TPK-......SRYIYEKAIQEYYN--------IDLKPDELLVRVP-h......
A0A1S5RGQ2_9VIRU/298-409 ......................n-EREIYDLDY.AIVKAKDLKPSFT.................-TGGTQKR...-TD.MNEEQIKSISQNFDPKKIFGSGG-.FEDLPII.........................................................L.HDG..QVIAGNHRIQGMLNF...TPK-......SRYIYNKAIQEYYN--------IDLKPDELLVRVP-n......
A0A1S5RFG7_9VIRU/1196-1307 ......................n-EREIYDLDY.AIVKAKDLKPSFT.................-TGGTQKR...-TD.MNEEQIKSIAENFDPKKIFGSGG-.FEDLPII.........................................................L.HDG..QVIAGNHRVQGMLNF...TPK-......SRFSYERAIKEYYH--------IDLKPDELLVRVP-h......
E7G4N4_9HELI/243-355 ......................d-DTHIYLLDF.VVVKTTDVKPNMQ.................AKSGVQTR...-TQ.TDLNKVAEIANNFKPEYVINRGG-.FDDLPII.........................................................I.NDG..QVIVGNHRALGMQEF...SPE-......SRKAYEQAISNTYG--------IELKHDELLVRTP-k......
A0A249PFF4_9RHIZ/310-438 ......................a-DGNSIGVSY.EVVEASTLITSHGddltp.......npafpPELQPRDR...SRA.LSQDQISGIAANLQPERLGFSPQA.ESGAPIV.........................................................G.PDG..LVESGNGRVLALRRA...YNQGg....vPADNYRNFLRSQNF----D---VEGMNNPVLIARR-v......
A0A1S5RF23_9VIRU/1186-1297 ......................n-EREIYDLDY.AIVKAKDLKPSFT.................-TGGTQKR...-TD.MNEEQIKSIAENFDPKKIFGSGG-.FEDLPII.........................................................L.HDG..QVIAGNHRIQGMLNF...TPK-......SRYIYHKAIKEYYN--------IDLKPDELLVRVP-n......
A0A1G3JKH8_9SPHN/870-993 ......................d-TGTEIDTEF.QVVEARDLITSSDag.............fdQRFQPRDR..aGRS.SSDAQIADIASRLDPAQLGRARLA.SQGAPII.........................................................G.PDR..MVESGNGRASAIRRA...YDMNp....eRAAEYRRMIDDM----GFD---TSGMQQPVLVRRR-l......
F8KQN1_HELBC/463-575 ......................d-DARIYPLDF.VIVKTSDVKPNLN.................AGVGTQTR...-TQ.TNPQRIEEIAKDFKPTMVFNRGG-.FDDLPII.........................................................L.SDG..QVIAGNHRAKGMQSF...SPQ-......SREAYEKAVLEHYN--------IKLQSDELLLRTP-k......
A0A1S5RFV6_9VIRU/1174-1285 .......................NDDEIHPLKF.VIVNKSDLKPNFK.................-NTGTQTR...-TA.VDSKKVEEIAKRFDPKLIIGRGG-.FDDLPII.........................................................L.PDG..QIIAGNHRAQGMLNF...NSE-......SRKKYEQAIKENFN--------IELKPNELLVRMP-e......
A0A1S9ZUA0_MORBO/586-710 ......................n-QNERLPTQI.MAVEADSLMPSVD................nTTNQARDR...SRT.ASRVQVDNIANNLDPMQLTDSTVM.GHGSPTI.........................................................S.DDG..TIIAGNGRTMAIKQA...YLQG......KADEYRQMLMERADEYGLDKTALAGMKNPVLVKS--vg.....
A0A0Q7Z659_9SPHN/546-663 .....................pt--GGKIDVRM.ELVSADDITQAEG.................-SKQNRDR...DRA.ASEAQIMAIVGKFDPEQLGDDNYT.DRGAPII.........................................................G.PDG..TIESGNGRVLAINRV...FDERp....eLAQQYRDYIESQ----GFD---TKGVDRPVLIRRR-v......
A5WEY6_PSYWF/72-205 ......................a-KGSRVSTIL.AVTEIDNVIASHTasgsq.......npiypQELQPRDR...GRD.SSVAWVQKVSRDLDPESLGRSGRA.DSGAPIV.........................................................G.DDM..AVESGNGRTMAIAMA...YDNG......TADDYRDWLIDEADYLGFSPKDVEAFKRPILIRIR-t......
A0A1V0M4M1_9GAMM/35-168 ......................v-NGEKVKTAF.NIVETSDLIISNHpdgri.......naaypQALQPRDR...TRL.SSQLQVNAIAKSLQPAQLADSALS.GEGAPIT.........................................................G.RDH..IVESGNGRSMGIVKA...YANG......SADAYKDYLIQNAPEYGLNSALIADMARPVLIRVR-l......
A0A268TWB6_9HELI/709-827 ......................v-NGKDYKATF.KLIEKDDLKPNFT.................-NSKTQYR...-LE.DNKVAKANLANFNANTHLNISNQTlEDGVPLL.........................................................D.KLG..NIISGNHRSQKLLGL...TPL-......EKKSYEEALAKFL---GDKKDLLKNYSNPILIRVL-d......
E1GWG1_9BACT/1274-1410 .....................fd--DKNIPSGYvALIDADELQPSHKngqrn.......plhfiDEAQPKER...KDD.ASKEAARKIASNIRPEEITSSVTA.YTGAPTV.........................................................N.SRG..EVIQGNNRSAALKEMwaaYKD-......KGEKYKQYLIDHAAELGLNSDKVRAMEKPILVNML-d......
A0A1L3ZY23_9SPHN/394-511 .....................pa--GNRVRTRF.EVVDSRALKAAEG.................-DLQNRDR...SRA.STDIQVQDIVSKFDPTRLGDSAET.DRGAPII.........................................................G.PDD..VVESGNGRMLALNRV...FDEFp....dRAQAYRDYLESQ----GHR---TEGIERPVLVRRR-v......
A0A1S5RG62_9VIRU/1183-1294 .......................NDDEIHPLKF.VIVNKSDLKPNFK.................-NTGTQTR...-TA.VDSKKVEEIAKRFDPKLIIGRGG-.FDDLPII.........................................................L.QDG..QVIAGNHRIQGMLNF...NAE-......SRKKYEQAIKHNFN--------ISLNPNELLVRMP-e......
A0A099U6B5_9HELI/315-427 ......................l-ENKTYNAKY.VIIKKQDLKPNFS.................-NTGTQGR...-LI.KQTRVIEDIQNNLNPNKLFFSEGG.FDGLPVI.........................................................L.ADG..SVSVGNHRAEALKNL...SKE-......SLQIYKEEAKKTFN--------VDLREDEVIVRML-d......
A0A1N6K1P7_9BURK/575-751 ................adasvgd---------A.SPMSSDVSAPQMV.................--LQNRDR...SSS.AAIHQMNDIAANPDPGRLSFSRDF.ANGAPVVeanpgveipadrlgrqdfaiasdgrrip.vqyavvdadtllpsnnadgssvaayaqgA.PDK.lRAIAGNARVAGLKAA...YDRG......TTAAYRAMIAQDQPLTGVSASGVQGLHNPVLVRIM-p......
#=GC seq_cons ......................s.csphhchpa.tlVcuc-LtsShs..................shpspcR....ps.ssppQlppIApshcPcplhsSst...cGsPIl.........................................................t.tDG...V.uGNtRshuhtph...htp.......stpsYcphlpchht........lshhss.lLVRh..p......
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