GenomeNet

Database: Pfam
Entry: hEGF
LinkDB: hEGF
Original site: hEGF 
#=GF ID   hEGF
#=GF AC   PF12661.8
#=GF DE   Human growth factor-like EGF
#=GF AU   Wouters M;0000-0002-2121-912X
#=GF AU   Coggill P;0000-0001-5731-1588
#=GF SE   Wouters M
#=GF GA   29.30 13.60;
#=GF TC   29.30 13.60;
#=GF NC   29.20 13.50;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 47079205 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Domain
#=GF WK   EGF-like_domain
#=GF RN   [1]
#=GF RM   15772310
#=GF RT   Evolution of distinct EGF domains with specific functions.
#=GF RA   Wouters MA, Rigoutsos I, Chu CK, Feng LL, Sparrow DB, Dunwoodie
#=GF RA   SL;
#=GF RL   Protein Sci. 2005;14:1091-1103.
#=GF DR   INTERPRO; IPR013032;
#=GF DR   SO; 0000417; polypeptide_domain;
#=GF CC   hEGF, or human growth factor-like EGF, domains have six
#=GF CC   conserved residues disulfide-bonded into the characteristic
#=GF CC   'ababcc' pattern. They are involved in growth and proliferation
#=GF CC   of cells, in proteins of the Notch/Delta pathway, neurogulin and
#=GF CC   selectins. hEGFs are also found in mosaic proteins with
#=GF CC   four-disulfide laminin EGFs such as aggrecan and perlecan.  The
#=GF CC   core fold of the EGF domain consists of two small beta-hairpins
#=GF CC   packed against each other. Two major structural variants have
#=GF CC   been identified based on the structural context of the
#=GF CC   C-terminal Cys residue of disulfide 'c' in the C-terminal
#=GF CC   hairpin: hEGFs and cEGFs. In hEGFs the C-terminal thiol resides
#=GF CC   in the beta-turn, resulting in shorter loop-lengths between the
#=GF CC   Cys residues of disulfide 'c', typically C[8-9]XC.  These
#=GF CC   shorter loop-lengths are also typical of the four-disulfide EGF
#=GF CC   domains, laminin ad integrin.  Tandem hEGF domains have six
#=GF CC   linking residues between terminal cysteines of adjacent domains.
#=GF CC   hEGF domains may or may not bind calcium in the linker region.
#=GF CC   hEGF domains with the consensus motif CXD4X[F,Y]XCXC are
#=GF CC   hydroxylated exclusively in the Asp residue.
#=GF SQ   18226
#=GS A0A482X2P2_LAOST/2326-2347  AC A0A482X2P2.1
#=GS A0A2K6DXW7_MACNE/1143-1164  AC A0A2K6DXW7.1
#=GS FBP1_STRPU/717-738          AC P10079.2
#=GS A0A3Q7SK20_VULVU/521-542    AC A0A3Q7SK20.1
#=GS G5AW14_HETGA/559-579        AC G5AW14.1
#=GS F7A4S6_CALJA/587-606        AC F7A4S6.1
#=GS A0A1U7QN09_MESAU/712-731    AC A0A1U7QN09.1
#=GS A0A087XGE3_POEFO/954-975    AC A0A087XGE3.2
#=GS A0A151NCY9_ALLMI/535-555    AC A0A151NCY9.1
#=GS A0A2K6MJM9_RHIBE/219-241    AC A0A2K6MJM9.1
#=GS A0A1S3RWT6_SALSA/579-598    AC A0A1S3RWT6.1
#=GS A0A0M4EWT3_DROBS/120-138    AC A0A0M4EWT3.1
#=GS A0A482V7B2_9CUCU/1153-1175  AC A0A482V7B2.1
#=GS G1RNU3_NOMLE/587-606        AC G1RNU3.1
#=GS A0A3P8Q1B6_ASTCA/713-732    AC A0A3P8Q1B6.1
#=GS A0A2U3YKJ7_LEPWE/329-347    AC A0A2U3YKJ7.1
#=GS A0A3Q2E3S5_CYPVA/1211-1230  AC A0A3Q2E3S5.1
#=GS A0A3B3D1U1_ORYME/793-813    AC A0A3B3D1U1.1
#=GS G1RP75_NOMLE/438-458        AC G1RP75.2
#=GS M3YIS6_MUSPF/1056-1074      AC M3YIS6.1
#=GS A0A2I3SKB0_PANTR/550-571    AC A0A2I3SKB0.1
#=GS A0A232EMS4_9HYME/131-152    AC A0A232EMS4.1
#=GS A0A1I7VVW3_LOALO/630-653    AC A0A1I7VVW3.1
#=GS A0A2R2MP02_LINUN/225-243    AC A0A2R2MP02.1
#=GS A0A1D5QXS1_MACMU/308-328    AC A0A1D5QXS1.1
#=GS K1PKL6_CRAGI/117-137        AC K1PKL6.1
#=GS A0A482XAW2_LAOST/84-104     AC A0A482XAW2.1
#=GS A0A286ZQ21_PIG/1166-1185    AC A0A286ZQ21.1
#=GS A0A2K6DXW7_MACNE/1354-1375  AC A0A2K6DXW7.1
#=GS M7BGM2_CHEMY/113-130        AC M7BGM2.1
#=GS U3JG63_FICAL/498-521        AC U3JG63.1
#=GS A0A1L8F124_XENLA/574-594    AC A0A1L8F124.1
#=GS A0A498N3T8_LABRO/519-538    AC A0A498N3T8.1
#=GS Q7QFS2_ANOGA/693-714        AC Q7QFS2.5
#=GS A0A3Q7VAW9_URSAR/858-878    AC A0A3Q7VAW9.1
#=GS W4ZEF6_STRPU/6484-6505      AC W4ZEF6.1
#=GS A0A088ACI3_APIME/1219-1240  AC A0A088ACI3.1
#=GS A0A2K6P7J9_RHIRO/490-511    AC A0A2K6P7J9.1
#=GS A0A2Y9SXG0_PHYMC/551-572    AC A0A2Y9SXG0.1
#=GS R0LAY5_ANAPL/217-235        AC R0LAY5.1
#=GS A0A3Q1C7D2_AMPOC/1141-1161  AC A0A3Q1C7D2.1
#=GS A0A3B3DP59_ORYME/587-606    AC A0A3B3DP59.1
#=GS A0A3P8ZZ77_ESOLU/202-220    AC A0A3P8ZZ77.1
#=GS A0A0V0VR41_9BILA/430-451    AC A0A0V0VR41.1
#=GS A0A2K5EJA2_AOTNA/1153-1174  AC A0A2K5EJA2.1
#=GS A0A1D2NMB5_ORCCI/2165-2185  AC A0A1D2NMB5.1
#=GS A0A2K5JCB4_COLAP/119-140    AC A0A2K5JCB4.1
#=GS A0A3F2YXP8_ANOFN/1128-1148  AC A0A3F2YXP8.2
#=GS A0A1A9ZTK0_GLOPL/911-930    AC A0A1A9ZTK0.1
#=GS G3S1M5_GORGO/712-731        AC G3S1M5.2
#=GS W4Z8A2_STRPU/173-190        AC W4Z8A2.1
#=GS A7T4U6_NEMVE/53-73          AC A7T4U6.1
#=GS A0A493T7J8_ANAPP/1123-1142  AC A0A493T7J8.1
#=GS A0A3P8RY22_AMPPE/590-610    AC A0A3P8RY22.1
#=GS A0A3B3W1I9_9TELE/119-139    AC A0A3B3W1I9.1
#=GS A0A1S3I663_LINUN/498-519    AC A0A1S3I663.1
#=GS A0A183I0C2_9BILA/1042-1063  AC A0A183I0C2.1
#=GS A0A2K5P823_CERAT/240-259    AC A0A2K5P823.1
#=GS H2ZJD0_CIOSA/2085-2105      AC H2ZJD0.1
#=GS A0A3Q3FA92_9LABR/124-145    AC A0A3Q3FA92.1
#=GS B3SCF5_TRIAD/123-143        AC B3SCF5.1
#=GS A0A3B5AJ77_9TELE/572-592    AC A0A3B5AJ77.1
#=GS H3ADH5_LATCH/308-327        AC H3ADH5.1
#=GS A0A2K6Q0U3_RHIRO/287-308    AC A0A2K6Q0U3.1
#=GS A0A1J1HNN2_9DIPT/264-282    AC A0A1J1HNN2.1
#=GS A0A091IJ66_CALAN/190-208    AC A0A091IJ66.1
#=GS A0A3B3VTM9_9TELE/625-643    AC A0A3B3VTM9.1
#=GS W4ZE00_STRPU/43-60          AC W4ZE00.1
#=GS F7FTM6_ORNAN/494-511        AC F7FTM6.1
#=GS A0A2I3SKP8_PANTR/753-773    AC A0A2I3SKP8.1
#=GS A0A401P421_SCYTO/125-143    AC A0A401P421.1
#=GS A0A1A6HX34_NEOLE/14-31      AC A0A1A6HX34.1
#=GS A0A3B4TAC3_SERDU/739-759    AC A0A3B4TAC3.1
#=GS A0A3Q3AY02_KRYMA/3589-3607  AC A0A3Q3AY02.1
#=GS A0A2A3EE67_APICC/187-205    AC A0A2A3EE67.1
#=GS A0A3Q3B989_KRYMA/782-803    AC A0A3Q3B989.1
#=GS A0A3Q3N234_9TELE/916-937    AC A0A3Q3N234.1
#=GS A0A2R2MKN1_LINUN/249-270    AC A0A2R2MKN1.1
#=GS A0A3P8ZZ77_ESOLU/635-654    AC A0A3P8ZZ77.1
#=GS A0A2D0QWC4_ICTPU/329-348    AC A0A2D0QWC4.1
#=GS A0A384D633_URSMA/377-397    AC A0A384D633.1
#=GS G3WDB2_SARHA/502-521        AC G3WDB2.1
#=GS A0A3Q2HZN5_HORSE/908-929    AC A0A3Q2HZN5.1
#=GS A0A452SQ89_URSAM/634-653    AC A0A452SQ89.1
#=GS A0A3Q1HZA4_9TELE/392-418    AC A0A3Q1HZA4.1
#=GS H3DMI5_TETNG/638-658        AC H3DMI5.1
#=GS A0A452H4C9_9SAUR/498-519    AC A0A452H4C9.1
#=GS A7SPC4_NEMVE/1-24           AC A7SPC4.1
#=GS A0A3Q3MUU7_9TELE/456-477    AC A0A3Q3MUU7.1
#=GS A0A2Y9M9I9_DELLE/895-915    AC A0A2Y9M9I9.1
#=GS B3N1W3_DROAN/646-666        AC B3N1W3.2
#=GS A0A2U9CE10_SCOMX/1387-1408  AC A0A2U9CE10.1
#=GS H0VU21_CAVPO/214-236        AC H0VU21.2
#=GS H2MBC4_ORYLA/117-138        AC H2MBC4.2
#=GS A0A2K5ZTI2_MANLE/1311-1332  AC A0A2K5ZTI2.1
#=GS F6PHD6_HORSE/280-301        AC F6PHD6.2
#=GS H2MIG7_ORYLA/414-433        AC H2MIG7.2
#=GS A0A3B4Z284_9TELE/1291-1312  AC A0A3B4Z284.1
#=GS A0A2I3T680_PANTR/456-471    AC A0A2I3T680.1
#=GS G5C0B3_HETGA/1297-1318      AC G5C0B3.1
#=GS A0A0L0G4I0_9EUKA/868-886    AC A0A0L0G4I0.1
#=GS A0A016TIA0_9BILA/2145-2163  AC A0A016TIA0.1
#=GS A0A3Q2FUD3_CYPVA/607-627    AC A0A3Q2FUD3.1
#=GS A0A0V1NJJ2_9BILA/2456-2473  AC A0A0V1NJJ2.1
#=GS A0A3Q3ALZ7_KRYMA/483-501    AC A0A3Q3ALZ7.1
#=GS A0A2I3LN94_PAPAN/337-357    AC A0A2I3LN94.1
#=GS R0LV80_ANAPL/281-300        AC R0LV80.1
#=GS R0K4D5_ANAPL/39-60          AC R0K4D5.1
#=GS A0A3Q1I9P3_ANATE/221-240    AC A0A3Q1I9P3.1
#=GS A0A2Y9G049_TRIMA/136-160    AC A0A2Y9G049.1
#=GS A0A0V1HAV4_9BILA/1151-1170  AC A0A0V1HAV4.1
#=GS A0A452SQH5_URSAM/371-390    AC A0A452SQH5.1
#=GS A0A140T8S0_MOUSE/501-520    AC A0A140T8S0.2
#=GS A0A2I4CBY6_9TELE/1346-1367  AC A0A2I4CBY6.1
#=GS G3WCE6_SARHA/403-423        AC G3WCE6.1
#=GS A0A287BEI6_PIG/234-253      AC A0A287BEI6.1
#=GS A0A1S2ZYB7_ERIEU/1346-1367  AC A0A1S2ZYB7.1
#=GS A0A2G8JKW2_STIJA/9-30       AC A0A2G8JKW2.1
#=GS A0A1S3I1X7_LINUN/470-491    AC A0A1S3I1X7.1
#=GS W4Z8A2_STRPU/353-370        AC W4Z8A2.1
#=GS A0A2K6LUJ8_RHIBE/336-357    AC A0A2K6LUJ8.1
#=GS A0A2K5U7Q9_MACFA/725-745    AC A0A2K5U7Q9.1
#=GS A0A2A2JPL0_9BILA/165-184    AC A0A2A2JPL0.1
#=GS A0A016TTU3_9BILA/91-112     AC A0A016TTU3.1
#=GS A0A3B5QGZ8_XIPMA/1349-1370  AC A0A3B5QGZ8.1
#=GS U3I4Q8_ANAPP/111-130        AC U3I4Q8.2
#=GS A0A0V1MUM2_9BILA/3086-3108  AC A0A0V1MUM2.1
#=GS A0A2A4IX66_HELVI/1335-1354  AC A0A2A4IX66.1
#=GS X1WJK3_ACYPI/232-250        AC X1WJK3.1
#=GS A0A3Q7S4K8_VULVU/501-520    AC A0A3Q7S4K8.1
#=GS A0A3B3BEJ0_ORYME/337-362    AC A0A3B3BEJ0.1
#=GS A0A2U3X0W2_ODORO/218-236    AC A0A2U3X0W2.1
#=GS W4ZBG5_STRPU/215-236        AC W4ZBG5.1
#=GS A0A3B5AW11_9TELE/194-213    AC A0A3B5AW11.1
#=GS A0A3Q0R3Z7_AMPCI/127-151    AC A0A3Q0R3Z7.1
#=GS M7AX84_CHEMY/862-883        AC M7AX84.1
#=GS A0A182M9E7_9DIPT/237-256    AC A0A182M9E7.1
#=GS A0A3Q7Y9M4_CICAR/201-224    AC A0A3Q7Y9M4.1
#=GS A0A0A0AKJ9_CHAVO/362-383    AC A0A0A0AKJ9.1
#=GS A8X9N5_CAEBR/1088-1109      AC A8X9N5.1
#=GS B3SE65_TRIAD/135-155        AC B3SE65.1
#=GS A0A016V0J4_9BILA/306-326    AC A0A016V0J4.1
#=GS A0A3Q3BPV8_KRYMA/350-370    AC A0A3Q3BPV8.1
#=GS A0A498SFX1_ACAVI/1712-1731  AC A0A498SFX1.1
#=GS H3CGM1_TETNG/384-404        AC H3CGM1.1
#=GS A0A183VHU1_TRIRE/25-46      AC A0A183VHU1.1
#=GS F7EN18_CALJA/444-465        AC F7EN18.2
#=GS A0A1D5QIJ9_MACMU/483-504    AC A0A1D5QIJ9.1
#=GS A0A3Q3VII6_MOLML/421-440    AC A0A3Q3VII6.1
#=GS G1MTP6_MELGA/966-987        AC G1MTP6.2
#=GS A0A0P8XJ30_DROAN/1957-1978  AC A0A0P8XJ30.1
#=GS A0A2K5R3L9_CEBCA/712-731    AC A0A2K5R3L9.1
#=GS A0A2K5D309_AOTNA/1127-1146  AC A0A2K5D309.1
#=GS A0A2K5LWR7_CERAT/191-210    AC A0A2K5LWR7.1
#=GS A0A4D9EGK5_9SAUR/1158-1178  AC A0A4D9EGK5.1
#=GS W4XEP0_STRPU/523-543        AC W4XEP0.1
#=GS B4L961_DROMO/196-215        AC B4L961.1
#=GS A0A2K6FG13_PROCO/998-1019   AC A0A2K6FG13.1
#=GS A0A2U9B9X3_SCOMX/256-275    AC A0A2U9B9X3.1
#=GS A0A402FFW3_9SAUR/457-478    AC A0A402FFW3.1
#=GS B3N1N1_DROAN/795-813        AC B3N1N1.1
#=GS A0A3B3T0C7_9TELE/351-371    AC A0A3B3T0C7.1
#=GS A0A2G8LBK9_STIJA/307-324    AC A0A2G8LBK9.1
#=GS A0A2U3WYI5_ODORO/712-731    AC A0A2U3WYI5.1
#=GS A0A402EY05_9SAUR/1030-1049  AC A0A402EY05.1
#=GS D2HZW1_AILME/323-343        AC D2HZW1.1
#=GS F1Q0H7_CANLF/1308-1329      AC F1Q0H7.1
#=GS A0A2D0QWB9_ICTPU/283-302    AC A0A2D0QWB9.1
#=GS A0A2K5C3D5_AOTNA/215-236    AC A0A2K5C3D5.1
#=GS L1ICC9_GUITC/51-70          AC L1ICC9.1
#=GS A0A2I4CBF8_9TELE/66-91      AC A0A2I4CBF8.1
#=GS A0A3Q4GY47_NEOBR/811-832    AC A0A3Q4GY47.1
#=GS A0A2G8KML0_STIJA/840-863    AC A0A2G8KML0.1
#=GS W5KTW9_ASTMX/308-330        AC W5KTW9.2
#=GS A0A452ES21_CAPHI/299-320    AC A0A452ES21.1
#=GS A0A1I8PY58_STOCA/1847-1868  AC A0A1I8PY58.1
#=GS A0A2B4SXK5_STYPI/533-551    AC A0A2B4SXK5.1
#=GS A0A1U7TJS1_TARSY/874-894    AC A0A1U7TJS1.1
#=GS B4HY15_DROSE/286-304        AC B4HY15.1
#=GS G3GZW0_CRIGR/965-984        AC G3GZW0.1
#=GS A0A286XPG4_CAVPO/128-146    AC A0A286XPG4.1
#=GS G3PUD0_GASAC/604-624        AC G3PUD0.1
#=GS A0A2I3T0D0_PANTR/967-988    AC A0A2I3T0D0.1
#=GS A0A3Q3XCW7_MOLML/591-612    AC A0A3Q3XCW7.1
#=GS M3XTT9_MUSPF/1129-1150      AC M3XTT9.1
#=GS A0A2K5R3E6_CEBCA/250-267    AC A0A2K5R3E6.1
#=GS A0A1S3K9X3_LINUN/201-218    AC A0A1S3K9X3.1
#=GS G1PCL2_MYOLU/254-271        AC G1PCL2.1
#=GS A0A2K5D309_AOTNA/955-974    AC A0A2K5D309.1
#=GS C3YL41_BRAFL/414-432        AC C3YL41.1
#=GS A0A1S3JYS6_LINUN/865-884    AC A0A1S3JYS6.1
#=GS A0A1L8G0B5_XENLA/670-688    AC A0A1L8G0B5.1
#=GS A0A3Q3W7C4_MOLML/118-142    AC A0A3Q3W7C4.1
#=GS A0A2K6DXX2_MACNE/1040-1061  AC A0A2K6DXX2.1
#=GS A0A3P8V032_CYNSE/845-862    AC A0A3P8V032.1
#=GS A0A3Q2E3F8_CYPVA/87-105     AC A0A3Q2E3F8.1
#=GS A0A2K5J7F4_COLAP/519-539    AC A0A2K5J7F4.1
#=GS E1JHA6_DROME/2148-2170      AC E1JHA6.1
#=GS A0A2D0QXB8_ICTPU/461-478    AC A0A2D0QXB8.1
#=GS A0A3B3VN97_9TELE/241-258    AC A0A3B3VN97.1
#=GS W5JI96_ANODA/1283-1304      AC W5JI96.1
#=GS A0A1S3G813_DIPOR/796-817    AC A0A1S3G813.1
#=GS A0A0V0UAN7_9BILA/798-817    AC A0A0V0UAN7.1
#=GS A0A1S3M8T1_SALSA/116-133    AC A0A1S3M8T1.1
#=GS A0A2K5QRZ6_CEBCA/358-379    AC A0A2K5QRZ6.1
#=GS A0A2K6FD62_PROCO/18-38      AC A0A2K6FD62.1
#=GS A0A452FPD8_CAPHI/230-252    AC A0A452FPD8.1
#=GS A0A182UVK1_ANOME/262-281    AC A0A182UVK1.1
#=GS G3S172_GORGO/627-647        AC G3S172.2
#=GS A0A0L8IIK4_OCTBM/803-824    AC A0A0L8IIK4.1
#=GS A0A3Q2VQC4_HAPBU/576-596    AC A0A3Q2VQC4.1
#=GS A0A4D9EUV6_9SAUR/1595-1616  AC A0A4D9EUV6.1
#=GS A0A3Q7VVX9_URSAR/474-495    AC A0A3Q7VVX9.1
#=GS A0A1S3L106_SALSA/87-105     AC A0A1S3L106.1
#=GS A0A3B3Q8C9_9TELE/1055-1076  AC A0A3B3Q8C9.1
#=GS H2P962_PONAB/541-562        AC H2P962.2
#=GS A0A0A0AJG1_CHAVO/1200-1218  AC A0A0A0AJG1.1
#=GS A0A182J2I7_9DIPT/257-276    AC A0A182J2I7.1
#=GS M9PGU6_DROME/408-427        AC M9PGU6.1
#=GS A0A452J4S9_9SAUR/1222-1240  AC A0A452J4S9.1
#=GS H2UIN4_TAKRU/714-733        AC H2UIN4.2
#=GS H2Z4I6_CIOSA/386-405        AC H2Z4I6.1
#=GS A0A2I3RZT2_PANTR/1183-1202  AC A0A2I3RZT2.1
#=GS W4ZEQ7_STRPU/170-187        AC W4ZEQ7.1
#=GS C3Z444_BRAFL/1-12           AC C3Z444.1
#=GS B4HGM0_DROSE/916-934        AC B4HGM0.1
#=GS A0A369SFF2_9METZ/2222-2244  AC A0A369SFF2.1
#=GS A0A1I8NB36_MUSDO/592-611    AC A0A1I8NB36.1
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#=GS A0A3P8Q494_ASTCA/1090-1110  AC A0A3P8Q494.1
#=GS A0A2H2I967_CAEJA/1929-1951  AC A0A2H2I967.1
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#=GS A0A0V0TCM5_9BILA/3379-3400  AC A0A0V0TCM5.1
#=GS H0VJG2_CAVPO/556-577        AC H0VJG2.2
#=GS A0A3P9CAR1_9CICH/739-760    AC A0A3P9CAR1.1
#=GS A0A091CVF6_FUKDA/627-649    AC A0A091CVF6.1
#=GS A0A1L8GRM4_XENLA/384-404    AC A0A1L8GRM4.1
#=GS A0A0Q3P584_AMAAE/858-877    AC A0A0Q3P584.1
#=GS A0A3Q3MLV3_9TELE/422-443    AC A0A3Q3MLV3.1
#=GS C3YQN6_BRAFL/501-521        AC C3YQN6.1
#=GS A0A3Q1B3X6_AMPOC/291-309    AC A0A3Q1B3X6.1
#=GS C3ZMG6_BRAFL/2-22           AC C3ZMG6.1
#=GS H2R3X3_PANTR/233-254        AC H2R3X3.1
#=GS A0A1S3N995_SALSA/2928-2946  AC A0A1S3N995.1
#=GS A0A452C7Q8_BALAS/347-367    AC A0A452C7Q8.1
#=GS H3FC00_PRIPA/409-426        AC H3FC00.2
#=GS A0A1J1IAH3_9DIPT/246-265    AC A0A1J1IAH3.1
#=GS A0A261ANW8_9PELO/1488-1506  AC A0A261ANW8.1
#=GS A0A087Y1F4_POEFO/145-166    AC A0A087Y1F4.2
#=GS A0A2K6T7L1_SAIBB/490-511    AC A0A2K6T7L1.1
#=GS A0A3Q2HN59_HORSE/30-49      AC A0A3Q2HN59.1
#=GS A0A0A0MUM5_PAPAN/438-459    AC A0A0A0MUM5.2
#=GS A0A0L8GF57_OCTBM/692-712    AC A0A0L8GF57.1
#=GS H2YPG3_CIOSA/345-366        AC H2YPG3.1
#=GS W4Y407_STRPU/2401-2422      AC W4Y407.1
#=GS A0A2K5I781_COLAP/505-525    AC A0A2K5I781.1
#=GS W4XSK1_STRPU/101-122        AC W4XSK1.1
#=GS A0A2K6MJN8_RHIBE/361-381    AC A0A2K6MJN8.1
#=GS A0A2D0RSN0_ICTPU/37-56      AC A0A2D0RSN0.1
#=GS A0A452G2K5_CAPHI/501-520    AC A0A452G2K5.1
#=GS A0A3B3DQ03_ORYME/255-274    AC A0A3B3DQ03.1
#=GS A0A218V7K3_9PASE/417-438    AC A0A218V7K3.1
#=GS W4Y6F8_STRPU/804-824        AC W4Y6F8.1
#=GS G1NZA1_MYOLU/230-252        AC G1NZA1.1
#=GS A0A2K5P079_CERAT/1144-1165  AC A0A2K5P079.1
#=GS A0A2K6V0X0_SAIBB/239-259    AC A0A2K6V0X0.1
#=GS A0A2I4BF64_9TELE/873-895    AC A0A2I4BF64.1
#=GS A0A182N6Y6_9DIPT/1572-1593  AC A0A182N6Y6.1
#=GS A0A0D9R0Q4_CHLSB/998-1019   AC A0A0D9R0Q4.1
#=GS A0A1S3T091_SALSA/1127-1148  AC A0A1S3T091.1
#=GS A0A2D0QWB9_ICTPU/197-216    AC A0A2D0QWB9.1
#=GS W4ZEF6_STRPU/3754-3775      AC W4ZEF6.1
#=GS A0A3B3C1L6_ORYME/71-88      AC A0A3B3C1L6.1
#=GS A0A0L0FU25_9EUKA/510-531    AC A0A0L0FU25.1
#=GS A0A2I3GIH7_NOMLE/118-136    AC A0A2I3GIH7.1
#=GS A0A093GT00_DRYPU/149-168    AC A0A093GT00.1
#=GS A0A140T8S0_MOUSE/113-130    AC A0A140T8S0.2
#=GS U3J631_ANAPP/384-403        AC U3J631.2
#=GS A0A482WDQ0_9CUCU/74-91      AC A0A482WDQ0.1
#=GS A0A267DGY0_9PLAT/253-275    AC A0A267DGY0.1
#=GS A0A1S3RVE3_SALSA/584-603    AC A0A1S3RVE3.1
#=GS A0A151PEC1_ALLMI/437-458    AC A0A151PEC1.1
#=GS A0A2B4RM53_STYPI/1171-1192  AC A0A2B4RM53.1
#=GS A0A3B3I1N3_ORYLA/591-610    AC A0A3B3I1N3.1
#=GS G1KK99_ANOCA/1165-1186      AC G1KK99.1
#=GS NOTC1_HUMAN/1357-1375       AC P46531.4
#=GS A0A498SCG8_ACAVI/358-380    AC A0A498SCG8.1
#=GS A0A384CRW5_URSMA/587-606    AC A0A384CRW5.1
#=GS A0A3P8YII5_ESOLU/457-478    AC A0A3P8YII5.1
#=GS A0A2D0RLV3_ICTPU/107-131    AC A0A2D0RLV3.1
#=GS A0A183TGJ9_SCHSO/88-109     AC A0A183TGJ9.1
#=GS F6XWF1_ORNAN/1-18           AC F6XWF1.1
#=GS A0A3Q3BS86_HAPBU/155-174    AC A0A3Q3BS86.1
#=GS H2ZD22_CIOSA/1-18           AC H2ZD22.1
#=GS A0A1D5RBD2_MACMU/1233-1254  AC A0A1D5RBD2.1
#=GS W5MJS7_LEPOC/562-582        AC W5MJS7.1
#=GS A0A0V0VRF0_9BILA/229-250    AC A0A0V0VRF0.1
#=GS A0A2Y9DZQ1_TRIMA/240-259    AC A0A2Y9DZQ1.1
#=GS A0A091VSX3_OPIHO/10-28      AC A0A091VSX3.1
#=GS A0A2I3LJ84_PAPAN/219-241    AC A0A2I3LJ84.1
#=GS W4ZEF6_STRPU/3640-3661      AC W4ZEF6.1
#=GS A0A0P8ZJC6_DROAN/1971-1992  AC A0A0P8ZJC6.1
#=GS A0A1I8JU62_ANOFN/874-893    AC A0A1I8JU62.2
#=GS A0A2B4RKA5_STYPI/608-635    AC A0A2B4RKA5.1
#=GS X1WIF9_ACYPI/1061-1079      AC X1WIF9.1
#=GS A0A452IWU8_9SAUR/376-395    AC A0A452IWU8.1
#=GS E9GB00_DAPPU/262-280        AC E9GB00.1
#=GS A0A087Y1E9_POEFO/763-784    AC A0A087Y1E9.2
#=GS A0A0V1I2B9_9BILA/246-267    AC A0A0V1I2B9.1
#=GS A0A2K6RJ06_RHIRO/1347-1365  AC A0A2K6RJ06.1
#=GS A0A2B4RTL8_STYPI/184-206    AC A0A2B4RTL8.1
#=GS A0A3B4CG76_PYGNA/462-483    AC A0A3B4CG76.1
#=GS B3RRJ8_TRIAD/81-102         AC B3RRJ8.1
#=GS A0A067R5X8_ZOONE/245-264    AC A0A067R5X8.1
#=GS Q19350_CAEEL/723-742        AC Q19350.1
#=GS A0A482XFV1_LAOST/1098-1116  AC A0A482XFV1.1
#=GS A0A2B4S9T1_STYPI/954-975    AC A0A2B4S9T1.1
#=GS A0A287D5B3_ICTTR/452-471    AC A0A287D5B3.1
#=GS A0A1V4IPQ6_PATFA/770-790    AC A0A1V4IPQ6.1
#=GS A0A2K6QH22_RHIRO/308-328    AC A0A2K6QH22.1
#=GS A0A2I2YCZ6_GORGO/1136-1157  AC A0A2I2YCZ6.1
#=GS MEG10_HUMAN/415-434         AC Q96KG7.1
#=GS A0A060VY06_ONCMY/250-269    AC A0A060VY06.1
#=GS MEGF6_HUMAN/1048-1067       AC O75095.4
#=GS B3RZW2_TRIAD/53-74          AC B3RZW2.1
#=GS A0A498MW06_LABRO/406-426    AC A0A498MW06.1
#=GS A0A182EAG4_ONCOC/1416-1434  AC A0A182EAG4.1
#=GS E2C8V5_HARSA/217-238        AC E2C8V5.1
#=GS A0A3B4CZ87_PYGNA/405-425    AC A0A3B4CZ87.1
#=GS A0A369SDH9_9METZ/1753-1772  AC A0A369SDH9.1
#=GS A0A3Q1GU68_9TELE/396-414    AC A0A3Q1GU68.1
#=GS A0A0V0SIS9_9BILA/1388-1407  AC A0A0V0SIS9.1
#=GS A0A195CPQ7_9HYME/968-987    AC A0A195CPQ7.1
#=GS H3CMD6_TETNG/357-377        AC H3CMD6.1
#=GS A0A3M0JSS7_HIRRU/476-495    AC A0A3M0JSS7.1
#=GS A0A3Q2KYC6_HORSE/579-599    AC A0A3Q2KYC6.1
#=GS T1KU06_TETUR/2258-2279      AC T1KU06.1
#=GS A0A2R8Q0P0_DANRE/283-302    AC A0A2R8Q0P0.1
#=GS A0A162EDC0_9CRUS/750-771    AC A0A162EDC0.1
#=GS A7T8R8_NEMVE/51-72          AC A7T8R8.1
#=GS A0A3Q3WPE3_MOLML/442-463    AC A0A3Q3WPE3.1
#=GS H3AKG5_LATCH/619-638        AC H3AKG5.1
#=GS F6V2H4_XENTR/131-152        AC F6V2H4.1
#=GS A0A2K6ENC7_PROCO/690-710    AC A0A2K6ENC7.1
#=GS F1MAP4_RAT/197-216          AC F1MAP4.1
#=GS A0A096LYZ0_POEFO/685-705    AC A0A096LYZ0.1
#=GS W5QGV9_SHEEP/729-749        AC W5QGV9.1
#=GS W4ZAK1_STRPU/152-173        AC W4ZAK1.1
#=GS A0A3Q3NI49_9TELE/176-195    AC A0A3Q3NI49.1
#=GS H2QRE9_PANTR/197-216        AC H2QRE9.1
#=GS A0A0V0SIS9_9BILA/1173-1192  AC A0A0V0SIS9.1
#=GS A0A2K5JCZ4_COLAP/490-511    AC A0A2K5JCZ4.1
#=GS W4XS29_STRPU/526-547        AC W4XS29.1
#=GS G3WML4_SARHA/153-177        AC G3WML4.1
#=GS A0A401RZF9_CHIPU/1211-1230  AC A0A401RZF9.1
#=GS MEGF6_MOUSE/921-940         AC Q80V70.3
#=GS A0A452FS42_CAPHI/234-253    AC A0A452FS42.1
#=GS A0A2J7PJ04_9NEOP/614-634    AC A0A2J7PJ04.1
#=GS H2S134_TAKRU/1285-1305      AC H2S134.2
#=GS A0A1J1IPC7_9DIPT/1804-1825  AC A0A1J1IPC7.1
#=GS A0A3Q0CDH0_MESAU/850-870    AC A0A3Q0CDH0.1
#=GS A0A0V1NJ44_9BILA/2456-2473  AC A0A0V1NJ44.1
#=GS A0A182Y4Z3_ANOST/574-594    AC A0A182Y4Z3.1
#=GS A0A423TQC8_PENVA/768-789    AC A0A423TQC8.1
#=GS A0A2K6ENB0_PROCO/346-366    AC A0A2K6ENB0.1
#=GS A0A3B4EUP8_9CICH/702-723    AC A0A3B4EUP8.1
#=GS A0A1V4KBY5_PATFA/1664-1682  AC A0A1V4KBY5.1
#=GS A0A2I3MZI4_PAPAN/898-919    AC A0A2I3MZI4.1
#=GS A0A452SV86_URSAM/1327-1348  AC A0A452SV86.1
#=GS A0A2K6SCS0_SAIBB/197-216    AC A0A2K6SCS0.1
#=GS A0A384B325_BALAS/282-303    AC A0A384B325.1
#=GS A0A158QIE6_HYMNN/1031-1052  AC A0A158QIE6.1
#=GS A0A3P8RG98_ASTCA/460-479    AC A0A3P8RG98.1
#=GS A0A484B0M9_DRONA/1049-1070  AC A0A484B0M9.1
#=GS A0A3Q1FM81_9TELE/414-435    AC A0A3Q1FM81.1
#=GS A0A099ZKL3_TINGU/464-483    AC A0A099ZKL3.1
#=GS H7C557_HUMAN/926-945        AC H7C557.2
#=GS A0A3Q1I4C5_ANATE/502-521    AC A0A3Q1I4C5.1
#=GS H2NXW0_PONAB/896-916        AC H2NXW0.1
#=GS A0A337S717_FELCA/732-751    AC A0A337S717.1
#=GS M3ZMQ4_XIPMA/591-610        AC M3ZMQ4.2
#=GS W4YM12_STRPU/511-530        AC W4YM12.1
#=GS A0A3Q1HAU4_9TELE/226-246    AC A0A3Q1HAU4.1
#=GS D6WD05_TRICA/839-860        AC D6WD05.2
#=GS A0A093GPV9_DRYPU/431-452    AC A0A093GPV9.1
#=GS A0A2B4S912_STYPI/528-548    AC A0A2B4S912.1
#=GS A0A287D5B3_ICTTR/234-253    AC A0A287D5B3.1
#=GS A0A0V1D3Y2_TRIBR/447-468    AC A0A0V1D3Y2.1
#=GS A0A077Z1F0_TRITR/1294-1313  AC A0A077Z1F0.1
#=GS K7FA51_PELSI/487-508        AC K7FA51.1
#=GS A0A482XFV1_LAOST/942-964    AC A0A482XFV1.1
#=GS A0A0R3P5J3_DROPS/192-211    AC A0A0R3P5J3.1
#=GS A0A3B3YL71_9TELE/479-495    AC A0A3B3YL71.1
#=GS Q5T0V0_HUMAN/1347-1368      AC Q5T0V0.1
#=GS A0A4X3PAK6_PRIPA/543-564    AC A0A4X3PAK6.1
#=GS A0A1S3WFX7_ERIEU/1143-1164  AC A0A1S3WFX7.1
#=GS A0A0V0VR40_9BILA/430-451    AC A0A0V0VR40.1
#=GS A0A077ZJ51_TRITR/443-463    AC A0A077ZJ51.1
#=GS A0A2A4IX66_HELVI/183-202    AC A0A2A4IX66.1
#=GS A0A3Q7RQV2_VULVU/347-367    AC A0A3Q7RQV2.1
#=GS H9GLY5_ANOCA/411-430        AC H9GLY5.2
#=GS M3ZHP6_XIPMA/1122-1143      AC M3ZHP6.2
#=GS H0Z6Z3_TAEGU/746-767        AC H0Z6Z3.1
#=GS A0A2A2J2L6_9BILA/288-312    AC A0A2A2J2L6.1
#=GS A0A096MMM3_PAPAN/128-146    AC A0A096MMM3.1
#=GS H3DIG5_TETNG/661-679        AC H3DIG5.1
#=GS A0A2Y9JKK5_ENHLU/1338-1359  AC A0A2Y9JKK5.1
#=GS G3SJN3_GORGO/670-690        AC G3SJN3.2
#=GS EYS_DANRE/1502-1523         AC B8JI71.2
#=GS A0A2A3E7L3_APICC/807-828    AC A0A2A3E7L3.1
#=GS W4Z1R1_STRPU/476-497        AC W4Z1R1.1
#=GS H3BR81_HUMAN/156-175        AC H3BR81.1
#=GS G3TJH2_LOXAF/1334-1355      AC G3TJH2.1
#=GS A0A3Q0QYD4_AMPCI/499-518    AC A0A3Q0QYD4.1
#=GS A0A0V0TFL1_9BILA/2096-2118  AC A0A0V0TFL1.1
#=GS A0A0N4Y0E4_NIPBR/325-341    AC A0A0N4Y0E4.2
#=GS A0A3Q1JPC1_ANATE/143-167    AC A0A3Q1JPC1.1
#=GS A0A3B3S9C2_9TELE/126-149    AC A0A3B3S9C2.1
#=GS A0A1I8PY43_STOCA/1861-1882  AC A0A1I8PY43.1
#=GS A0A452FI39_CAPHI/474-494    AC A0A452FI39.1
#=GS D2WEZ3_HUMAN/191-213        AC D2WEZ3.1
#=GS H2SBP5_TAKRU/296-316        AC H2SBP5.2
#=GS A0A3Q3GTG6_9LABR/292-310    AC A0A3Q3GTG6.1
#=GS A0A1V4JJW6_PATFA/163-187    AC A0A1V4JJW6.1
#=GS A0A3Q2E3F8_CYPVA/1120-1140  AC A0A3Q2E3F8.1
#=GS A0A2G8JG78_STIJA/496-515    AC A0A2G8JG78.1
#=GS A0A3B5B479_9TELE/423-444    AC A0A3B5B479.1
#=GS A0A077Z1F0_TRITR/1036-1055  AC A0A077Z1F0.1
#=GS A0A3B4FR95_9CICH/109-131    AC A0A3B4FR95.1
#=GS A0A2I2UWB2_FELCA/467-487    AC A0A2I2UWB2.2
#=GS A0A1U7RXH3_ALLSI/587-606    AC A0A1U7RXH3.1
#=GS A0A099Z0N4_TINGU/2290-2312  AC A0A099Z0N4.1
#=GS A0A2K6RT91_RHIRO/128-146    AC A0A2K6RT91.1
#=GS A0A1X7VDH5_AMPQE/526-547    AC A0A1X7VDH5.1
#=GS A0A2K5W2S7_MACFA/986-1005   AC A0A2K5W2S7.1
#=GS A0A3Q0DQQ7_TARSY/157-174    AC A0A3Q0DQQ7.1
#=GS A0A3B1IW49_ASTMX/559-578    AC A0A3B1IW49.1
#=GS A0A2R9ACX2_PANPA/429-451    AC A0A2R9ACX2.1
#=GS W4Z0G5_STRPU/202-222        AC W4Z0G5.1
#=GS A0A2I4CBF8_9TELE/1426-1446  AC A0A2I4CBF8.1
#=GS F7CNG1_XENTR/512-533        AC F7CNG1.1
#=GS F2UJJ7_SALR5/32-49          AC F2UJJ7.1
#=GS A0A2I3LHI3_PAPAN/1111-1128  AC A0A2I3LHI3.1
#=GS A0A1S3PI54_SALSA/343-363    AC A0A1S3PI54.1
#=GS A0A2B4S6S8_STYPI/465-486    AC A0A2B4S6S8.1
#=GS A0A3Q1GCQ9_9TELE/354-374    AC A0A3Q1GCQ9.1
#=GS C3ZWV8_BRAFL/2434-2455      AC C3ZWV8.1
#=GS F7DBB2_MACMU/129-147        AC F7DBB2.2
#=GS A0A1S3T076_SALSA/1127-1148  AC A0A1S3T076.1
#=GS A0A3P9AZM0_9CICH/144-168    AC A0A3P9AZM0.1
#=GS A0A3P8UPJ8_CYNSE/1128-1149  AC A0A3P8UPJ8.1
#=GS A0A0R4IN59_DANRE/118-138    AC A0A0R4IN59.1
#=GS A0A3Q3MNY4_9TELE/300-322    AC A0A3Q3MNY4.1
#=GS A0A3Q3MXM2_9TELE/392-412    AC A0A3Q3MXM2.1
#=GS A0A2I3HD26_NOMLE/234-253    AC A0A2I3HD26.1
#=GS A0A2U9CGY7_SCOMX/2094-2116  AC A0A2U9CGY7.1
#=GS A0A3Q2FUD3_CYPVA/301-321    AC A0A3Q2FUD3.1
#=GS A0A3Q1JKF6_ANATE/1046-1067  AC A0A3Q1JKF6.1
#=GS A0A493U4E7_ANAPP/1351-1372  AC A0A493U4E7.1
#=GS E0VD28_PEDHC/220-243        AC E0VD28.1
#=GS A0A3B3CDC4_ORYME/283-302    AC A0A3B3CDC4.1
#=GS A0A2K6GHJ3_PROCO/1048-1069  AC A0A2K6GHJ3.1
#=GS B3RZ27_TRIAD/1427-1448      AC B3RZ27.1
#=GS H0Z808_TAEGU/240-259        AC H0Z808.1
#=GS A0A3Q7SWV4_VULVU/2887-2908  AC A0A3Q7SWV4.1
#=GS A0A3Q1JPM9_ANATE/283-302    AC A0A3Q1JPM9.1
#=GS A0A016TUH6_9BILA/106-127    AC A0A016TUH6.1
#=GS A0A3B4FJA2_9CICH/470-489    AC A0A3B4FJA2.1
#=GS A0A2R2MQD1_LINUN/303-324    AC A0A2R2MQD1.1
#=GS A0A3B4FQW6_9CICH/1309-1328  AC A0A3B4FQW6.1
#=GS A0A0Q3TCQ2_AMAAE/302-322    AC A0A0Q3TCQ2.1
#=GS F7DBW9_MACMU/119-137        AC F7DBW9.2
#=GS A0A182XX69_ANOST/539-558    AC A0A182XX69.1
#=GS F7DVB1_MONDO/711-732        AC F7DVB1.1
#=GS I3KE67_ORENI/242-261        AC I3KE67.1
#=GS W4YK15_STRPU/447-468        AC W4YK15.1
#=GS H3CMD6_TETNG/851-874        AC H3CMD6.1
#=GS A0A0V0ZQ87_9BILA/447-468    AC A0A0V0ZQ87.1
#=GS A0A3B4GUX7_9CICH/550-571    AC A0A3B4GUX7.1
#=GS A0A3S3PQ17_9ACAR/644-665    AC A0A3S3PQ17.1
#=GS A0A452GJW5_9SAUR/416-437    AC A0A452GJW5.1
#=GS H2TBP7_TAKRU/1221-1242      AC H2TBP7.2
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#=GS A0A2Y9N3R5_DELLE/15-35      AC A0A2Y9N3R5.1
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