GenomeNet

Database: Pfam
Entry: vMSA
LinkDB: vMSA
Original site: vMSA 
#=GF ID   vMSA
#=GF AC   PF00695.20
#=GF DE   Major surface antigen from hepadnavirus
#=GF AU   Bateman A;0000-0002-6982-4660
#=GF SE   Pfam-B_168 (release 2.1)
#=GF GA   29.10 29.10;
#=GF TC   88.70 59.60;
#=GF NC   23.00 22.70;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 47079205 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Family
#=GF DR   INTERPRO; IPR000349;
#=GF DR   SO; 0100021; polypeptide_conserved_region;
#=GF SQ   22
#=GS Q9QBE6_HBVB7/1-400        AC Q9QBE6.1
#=GS A0A193AUB7_9HEPA/149-293  AC A0A193AUB7.1
#=GS A0A2U8SZJ6_9HEPA/1-382    AC A0A2U8SZJ6.1
#=GS HBSAG_DHBVQ/1-267         AC Q66405.1
#=GS Q17UT6_HBVAW/1-226        AC Q17UT6.1
#=GS Q17UT0_HBVAW/1-400        AC Q17UT0.1
#=GS HBSAG_DHBV1/261-328       AC P03145.4
#=GS HBSAG_WHV1/104-426        AC P03143.1
#=GS A0A0V1ALW1_TRISP/1-270    AC A0A0V1ALW1.1
#=GS HBSAG_HBVCJ/1-400         AC Q76R62.2
#=GS HBSAG_DHBVQ/266-330       AC Q66405.1
#=GS HBSAG_HBVD3/1-389         AC P03138.3
#=GS Q7T418_9HEPA/104-426      AC Q7T418.1
#=GS A0A0M3P4Q2_9HEPA/132-278  AC A0A0M3P4Q2.1
#=GS Q17US9_HBVAW/1-281        AC Q17US9.1
#=GS A0A193AUI9_9HEPA/86-328   AC A0A193AUI9.1
#=GS Q9QBE5_HBVB7/1-281        AC Q9QBE5.1
#=GS U3M9X6_9HEPA/1-224        AC U3M9X6.1
#=GS A0A193AU90_9HEPA/281-422  AC A0A193AU90.1
#=GS HBSAG_GSHV/86-428         AC P03144.1
#=GS Q9QBE9_HBVB7/1-226        AC Q9QBE9.1
#=GS HBSAG_DHBV1/1-266         AC P03145.4
Q9QBE6_HBVB7/1-400                   ......................................MGGWSSKPRKGM......GTNL........SVPNPL....GFFP..DHQLD.................PAFKANS....ENPDWDLNPHKDNWPDAHKVGVGAFG..PGFTPPHGGLLG.WSPQAQGILTSVPAA.PPPASTNRQSGRQPTPLSPPLRDTHPQAVQWNSTTFHQTLQDPRVRAL.....YLPAGGSSSGTVSP.AQNTVSAISSILSKTGDPVP.NMENIASGL.....LGPLLVLQAGFFSLTKILTIPQSLDSWWTSLSFLGGTPVCLGQNSQSQISSHSPTCCPPICPGYRWMCLRRFIIFLCILLLCLIFLLVLLDYQGMLPVCPLIPGSSTTSTGPCKTCTTPAQGTSMFPSCCCTKPTDGNCTCIPIPSSWAFAKYLWEWASVRFSWLSLLVPFVQWFVGLSPTVWLSVIWMMWFWGPSLYNILSPFMPLLPIFLCLWVY-m.......
A0A193AUB7_9HEPA/149-293             aipvllaiptssstevgrlpyqiyphellpipkleeks------------......----........------....----..-----.................-------....--------------------------..------------.---------------.------------------------------------------------.....--------------.-----------------TTA.NMSGAVSPA.....LWFPVVALVVYFLLTKAREILAKLDWWWTSHSFRGANGECIFQDTSPQTQKHLAGFCPLTCGGFLWTSLRLFTICLIILLAV-CGYLFLME-------------------------------------------------------------------------------------------------------------------------------kgfts...
A0A2U8SZJ6_9HEPA/1-382               ......................................-----------M......GANQ........SIPNPL....GFFP..RHNLD.................LTDPA-G....TLGDFDHNPLKDPWPQSSHQSRGAWG..PGFVPPHGGLLGsLSFATQGVVSAQPITnPPPRK----KGRGPTPLTPPVRVTHPQMSPSSWRQKYGYLLLPKTTA-.....---APGPTSPPQTT.VAPTASSTSSPPLTIGAPAA.RMGNITSGP.....FGFLLGLQVGSFLWTKIQTIGQSADSWWTSLSFPGAIPGCIGQDSQYQTSKHSPTSCPPTCTGFPWMCLRRFIIYLLLLALLLIFSLVLLDWKGLLPVCPFPPGDSQTGNIRCKACIGSAPETPWPPLCCCTVPSDGNCTCWPIPSSWALGSYLWELALARFSWLSSLVVWLQWLGGISPIVWCLLIWMTWFWGLRVWNILSQFMPLLFLLFYHLV--yt......
HBSAG_DHBVQ/1-267                    ......................................MG---QQPAKSMdvrrieGGELllnqlagrMIPKGTvtwsGKFPtiDHLLDhvqtmeevntlqqqgawPA-GAGRrlglTNPTPHETPQPQWTPEEDQKAREAFRryQEERPPE-----.-------TTTIAPTS.PTPWKL--QPGDDPLLENKSLLETHP---------LYQ---NPE----.....--PA----------.VPVIKTP--------PLKKK.KMPGTFGGI.....LAGLIGLLVSFFLLIKILEILRRLDWWWISLSSPKGKMQCAFQDTGAQISQHYVGSCPWGCPGFLWTYLRLFIIFLLILLVA-AGLLYLTDNMSII--------------------------------------------------------------------------------------------------------------------------l.......
Q17UT6_HBVAW/1-226                   ......................................------------......----........------....----..-----.................-------....--------------------------..------------.---------------.------------------------------------------------.....--------------.--------------------.-MENITSGF.....LGPLLVLQAGFFLLTRILTIPQSLDSWWTSLNFLGGSPVCLGQNSQSPTSNHSPTSCPPICPGYRWMCLRRFIIFLFILLLCLIFLLVLLDYQGMLPVCPLIPGTTTTSTGPCKTCTTPAQGNSMFPSCCCTKPSDGNCTCIPIPSSWAFAKYLWEWASVRFSWLSLLVPFVQWFVGLSPTVWLSAIWMMWYWGPSLYSIVSPFIPLLPIFFCLWVYI........
Q17UT0_HBVAW/1-400                   ......................................MGGWSSKPRKGM......GTNL........SVPNPL....GFFP..DHQLD.................PAFGANS....NNPDWDFNPIKDHWPAANQVGVGAFG..PGFTPPHGGVLG.WSPQAQGILTTVSTI.PPPASTNRQSGRQPTPISPPLRDSHPQAMQWNSTAFHQALQDPKVRGL.....YFPAGGSSSGTVNP.APNIASHISSISARTGDPVT.NMENITSGF.....LGPLLVLQAGFFLLTRILTIPQSLDSWWTSLNFLGGSPVCLGQNSQSPTSNHSPTSCPPICPGYRWMCLRRFIIFLFILLLCLIFLLVLLDYQGMLPVCPLIPGTTTTSTGPCKTCTTPAQGNSMFPSCCCTKPSDGNCTCIPIPSSWAFAKYLWEWASVRFSWLSLLVPFVQWFVGLSPTVWLSAIWMMWYWGPSLYSIVSPFIPLLPIFFCLWVYI........
HBSAG_DHBV1/261-328                  ....................................gs------------......----........------....----..-----.................-------....--------------------------..------------.---------------.------------------------------------------------.....--------------.--------------------.---------.....---------------------------------------------------------------------------------------------------------------------------------------------------TILGKLQWASVSALFSSISSLLPSDP----KSLVALTFGLSLIWMTSSSATQTLVT-LTQLATLSALFYK-s.......
HBSAG_WHV1/104-426                   ...........................vpgirdiprgl------------......----........------....----..-----.................-------....--------------------------..------------.--------------V.PPQTPTNRDQGRKPTPPTPPLRDTHPHLTMKNQTFHLQGFVDGL-RDLttterQHNAYGDPFTTLSP.VVPTVSTILSPPSTTGDPAQ.SPEMSPSSL.....LGLLAGLQVVYFLWTKILTIAQNLDWWWTSLSFPGGIPECTGQNSQFQTCKHLPTSCPPTCNGFRWMYLRRFIIYLLVLLLCLIFLLVLLDWKGLIPVCPIQPTTETT--VNCRQCTISVQDMYTPPYCCCLKPTAGNCTCWPIPSSWALGNYLWEWALARFSWLNLLVPLLQWLGGISLIAWFLLIWMIWFWGPALLSILPPFIPIFVLFFLIWVYI........
A0A0V1ALW1_TRISP/1-270               ......................................------------......----........------....----..-----.................-------....--------------------------..------------.---------------.---------------------------------------LLDPRVRGL.....YLPAGGSSSGTVNP.VPTTASPISSIFSRTGDPAP.NMENTTSGF.....LGPLLVLQAGFFLLTRILTIPQSLDSWWTSLNFLGGAPTCPGQNSQSPTSNHSLTSCPPTCPGYRWMCLRRFIIFLFILLLCLIFLLVLLDYQGMLPVCPLLPGTSTTTTGPCKTCTTPAQGTSMFPSCCCTKPSDGNYICIPIPSSWAFARFLWEWASVRFSWLSLLVPFVQWFVGLSPTVWLSVIWMMWYWGPSLYNILSPFLPLLPIFFCLWVYI........
HBSAG_HBVCJ/1-400                    ......................................MGGWSSKPRQGM......GTNL........SVPNPL....GFFP..DHQLD.................PAFGANS....NNPDWDFNPNKDHWPEANQVGAGAFG..PGFTPPHGGLLG.WSPQAQGILTTLPAA.PPPASTNRQSGRQPTPISPPLRDSHPQAMQWNSTTFHQALLDPRVRGL.....YFPAGGSSSGTVNP.VPTTASPISSIFSRTGDPAP.NMESTTSGF.....LGPLLVLQAGFFLLTRILTIPQSLDSWWTSLNFLGGAPTCPGQNSQSPTSNHSPTSCPPTCPGYRWMCLRRFIIFLFILLLCLIFLLVLLDYQGMLPVCPLLPGTSTTSTGPCRTCTIPAQGTSMFPSCCCTKPSDGNCTCIPIPSSWAFARFLWEWASVRFSWLSLLVPFVQWFVGLSPTVWLSAIWMMWYWGPSLYNILSPFLPLLPIFFCLWVYI........
HBSAG_DHBVQ/266-330                  .....................................i------------......----........------....----..-----.................-------....--------------------------..------------.---------------.------------------------------------------------.....--------------.--------------------.---------.....-----------------------------------------------------------------------------------------------------------------------------------------------------LEKLQWESVSVLFSSISSLLPSDQ----KSLVALMFGLLLIWMTSSSATQTLVT-LTQLATLSVLFYKN........
HBSAG_HBVD3/1-389                    ......................................-----------M......GQNL........STSNPL....GFFP..DHQLD.................PAFRANT....ANPDWDFNPNKDTWPDANKVGAGAFG..LGFTPPHGGLLG.WSPQAQGILQTLPAN.PPPASTNRQSGRQPTPLSPPLRNTHPQAMQWNSTTFHQTLQDPRVRGL.....YFPAGGSSSGTVNP.VLTTASPLSSIFSRIGDPAL.NMENITSGF.....LGPLLVLQAGFFLLTRILTIPQSLDSWWTSLNFLGGTTVCLGQNSQSPTSNHSPTSCPPTCPGYRWMCLRRFIIFLFILLLCLIFLLVLLDYQGMLPVCPLIPGSSTTSTGPCRTCMTTAQGTSMYPSCCCTKPSDGNCTCIPIPSSWAFGKFLWEWASARFSWLSLLVPFVQWFVGLSPTVWLSVIWMMWYWGPSLYSILSPFLPLLPIFFCLWVYI........
Q7T418_9HEPA/104-426                 ...........................vpgirdiprgl------------......----........------....----..-----.................-------....--------------------------..------------.--------------V.PPQTPTNRDQGRKPTPPTPPLRDTHPHLTMKNQTFHLQGFVDGL-RDLttterQHNAYGDPFTTVSP.VVPTVSTILSPPSTTGDPAQ.SPEMSPSSL.....LGLLAGLQVVYFLWTKILTIAQNLDWWWTSLSFPGGIPECTGQNSQFQTCKHLPTSCPPTCNGFRWMYLRRFIIYLLVLLLCLIFLLVLLDWKGLIPVCPIQPTTETT--VNCRQCTISVQDMYTPPYCCCLKPTAGNCTCWPIPSSWALGNYLWEWALARFSWLNLLVPLLQWLGGISLIAWFLLIWMIWFWGPALLSILPPFIPIFVLFFLIWVYI........
A0A0M3P4Q2_9HEPA/132-278             ...................vpflapllipvahqtvrts------------......----........------....----..-----.................-------....--------------------------..------------.---------------.------------------------------------------------.....--------------.YNMTTSNISEIMDEARTAFT.TMGSAFQGLsfdlwVLFLVVLLVVFFLLIKIHTILKAADWWLISRSFL-GTQTCPFRNTESPTSMHFKTDCPLTCTGFRWTLVRRSIIFLCILALVVIFWY-----------------------------------------------------------------------------------------------------------------------------------lmawepft
Q17US9_HBVAW/1-281                   ......................................------------......----........------....----..-----.................-------....--------------------------..------------.---------------.----------------------------MQWNSTAFHQALQDPKVRGL.....YFPAGGSSSGTVNP.APNIASHISSISARTGDPVT.NMENITSGF.....LGPLLVLQAGFFLLTRILTIPQSLDSWWTSLNFLGGSPVCLGQNSQSPTSNHSPTSCPPICPGYRWMCLRRFIIFLFILLLCLIFLLVLLDYQGMLPVCPLIPGTTTTSTGPCKTCTTPAQGNSMFPSCCCTKPSDGNCTCIPIPSSWAFAKYLWEWASVRFSWLSLLVPFVQWFVGLSPTVWLSAIWMMWYWGPSLYSIVSPFIPLLPIFFCLWVYI........
A0A193AUI9_9HEPA/86-328              ...........................rtndrkktpvy------------......----........------....----..-----.................-------....--------------------------..------------.---------------.------------------------------------------------.....--------------.-HVTTAPTAAATAATPTSPP.QMTGFFSGW....eLGFPLVLQVVFFLWTKIHEIIGKLDSWWIFLSSPECLTGSGGLGLHPQISPHLPTNCQPGCPGYPWTCLRRFIIFLCILALFVILSLVYLDWIGML-FCCCCNGS------DCTNCTCSGS----NGKCCCVCKDCANCD----QCSWAFVKHLWALASAHFSWLSSLESLSSISAHSFKVSVVLLIWMMWWWGITLTSIWQVSFMLFTTYYFLW---gst.....
Q9QBE5_HBVB7/1-281                   ......................................------------......----........------....----..-----.................-------....--------------------------..------------.---------------.----------------------------MQWNSTTFHQTLQDPRVRAL.....YLPAGGSSSGTVSP.AQNTVSAISSILSKTGDPVP.NMENIASGL.....LGPLLVLQAGFFSLTKILTIPQSLDSWWTSLSFLGGTPVCLGQNSQSQISSHSPTCCPPICPGYRWMCLRRFIIFLCILLLCLIFLLVLLDYQGMLPVCPLIPGSSTTSTGPCKTCTTPAQGTSMFPSCCCTKPTDGNCTCIPIPSSWAFAKYLWEWASVRFSWLSLLVPFVQWFVGLSPTVWLSVIWMMWFWGPSLYNILSPFMPLLPIFLCLWVY-m.......
U3M9X6_9HEPA/1-224                   ....................................mg------------......----........------....----..-----.................-------....--------------------------..------------.---------------.------------------------------------------------.....--------------.--------------------.---NISSEL.....LGPLVGFQVVFFLWTKILTIAQSLDSWWTSLSFPGGIPECFGLNLQSQTCKHSPTSCPPTCAGFRWMCLRRFIIYLLVLLLCLIFLLVLLDWRGLLPVCPLNPNNQTT--MRCTSCTISADALTSFPYCCCSKPSGGNCTCWPIPSSWAFAKFLWELASLRFSWLNSLVPWLQWFAGLSPTAWLLAIWMMWYWGPGLLNTLSPFMPLFVLFFLLWGYI........
A0A193AU90_9HEPA/281-422             ...vllaiptssstevgrlpyqiyphellpipkleeks------------......----........------....----..-----.................-------....--------------------------..------------.---------------.------------------------------------------------.....--------------.-----------------TTA.NMSGAVSPA.....LWFPVVALVVYFLLTKAREILAKLDWWWTSHSFRGANGECIFQDTSPQTQKHLAGFCPLTCGGFLWTSLRLFTICLIILLAV-CGYLFLME-------------------------------------------------------------------------------------------------------------------------------kgfts...
HBSAG_GSHV/86-428                    .......nnppsgqraetfeiksrpiivpgirdiprgi------------......----........------....----..-----.................-------....--------------------------..------------.--------------V.PPQTPSNRDQRRKPTPLTPPLRDTHPHLTMKNQTGHLQGFAEGL-RALttsdhHNSAYGDPFTTLSPvVPTVSTTLSPPL-TIGDPVL.STEMSPSGL.....LGLLAGLQVVYFLWTKILTIAQSLDWWWTSLSFPGGIPECTGQNLQFQTCKHLPTSCPPTCNGFRWMYLRRFIIYLLVLLLFLTFLLVLLDWKGLLPVCPMMPATETT--VNCRQCTISAQDTFTTPYCCCLKPTAGNCTCWPIPSSWALGSYLWEWALARFSWLSLLVPLLQWLGGISLTVWLLLIWMIWFWGPVLMSILPPFIPIFALFFLIWAYI........
Q9QBE9_HBVB7/1-226                   ......................................------------......----........------....----..-----.................-------....--------------------------..------------.---------------.------------------------------------------------.....--------------.--------------------.-MENIASGL.....LGPLLVLQAGFFSLTKILTIPQSLDSWWTSLSFLGGTPVCLGQNSQSQISSHSPTCCPPICPGYRWMCLRRFIIFLCILLLCLIFLLVLLDYQGMLPVCPLIPGSSTTSTGPCKTCTTPAQGTSMFPSCCCTKPTDGNCTCIPIPSSWAFAKYLWEWASVRFSWLSLLVPFVQWFVGLSPTVWLSVIWMMWFWGPSLYNILSPFMPLLPIFLCLWVY-m.......
HBSAG_DHBV1/1-266                    ......................................MG---QHPAKSMdvrrieGGEIllnqlagrMIPKGTltwsGKFPtlDHVLDhvqtmeeintlqnqgawPA-GAGRrvglSNPTPQEIPQPQWTPEEDQKAREAFRryQEERPPE-----.-------TTTIPPSS.PPQWKL--QPGDDPLLGNQSLLETHP---------LYQ----SE----.....--PA----------.VPVIKTP----------PLKkKMSGTFGGI.....LAGLIGLLVSFFLLIKILEILRRLDWWWISLSSPKGKMQCAFQDTGAQISPHYVGSCPWGCPGFLWTYLRLFIIFLLILLVA-AGLLYLTDNGSTI--------------------------------------------------------------------------------------------------------------------------lg......
#=GC seq_cons                        ..................................................................................................................................................................................................................................................h.shho...........ss..pMpshsSGh.....LG.LlsLQssFFLLTKILTIsQsLD.WWTSLSF.GGts.ChGQNoQs.TSpH.PTsCPPsCsGaRWMsLRRFIIaLhILLLsLIFLLVLLDapGhlPVCPh.PssppT..h.CppChhsspt....P.CCChpPosGNCsChPIPSSWAhupaLWEhA.sRFSWLS.LVPhlQWhsGlS.ssWh.hIWMhWaWGsuLhsIlssFhPlhslahhlWsh.........
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