KEGG   Pyrolobus fumarii: Pyrfu_1581
Entry
Pyrfu_1581        CDS       T01620                                 
Name
(GenBank) 3-hydroxy-3-methylglutaryl Coenzyme A reductase
  KO
K00021  hydroxymethylglutaryl-CoA reductase (NADPH) [EC:1.1.1.34]
Organism
pfm  Pyrolobus fumarii
Pathway
pfm00900  Terpenoid backbone biosynthesis
pfm01100  Metabolic pathways
pfm01110  Biosynthesis of secondary metabolites
Module
pfm_M00849  C5 isoprenoid biosynthesis, mevalonate pathway, archaea
Brite
KEGG Orthology (KO) [BR:pfm00001]
 09100 Metabolism
  09109 Metabolism of terpenoids and polyketides
   00900 Terpenoid backbone biosynthesis
    Pyrfu_1581
Enzymes [BR:pfm01000]
 1. Oxidoreductases
  1.1  Acting on the CH-OH group of donors
   1.1.1  With NAD+ or NADP+ as acceptor
    1.1.1.34  hydroxymethylglutaryl-CoA reductase (NADPH)
     Pyrfu_1581
SSDB
Motif
Pfam: HMG-CoA_red
Other DBs
NCBI-ProteinID: AEM39438
UniProt: G0EC68
Position
1475689..1476969
AA seq 426 aa
MVEGRDLREIVERVVKGEVKLHELDKLLGNSNLAALVRRLALEKITGVSLSSIGSTILDF
EELVGRNIENPIGAVQVPVGIVGPLRVQGEYARGDFYVPLATTEGALVASVNRGAKAVTL
AGGAKTRILRDGMTRAPVIWTPSVEEAVKLVKWVEENIDVLKKAAESTTRHGKLKGLTWW
ITGNLVWLRFEFETGDAMGMNMVTIAVDKALQELLNNYDGDIRVVALSGNMCVDKKPSIL
NMLLGRGKTVVAEAIIPRDVVREVLKTTPEAIHEVNVAKNLMGSARAGSLSYNAHYANII
AAIFIATGQDVAQVVESSMGYTWTEVRNGDLYISVTLPSLEVGTVGGGTRLPTQREALAL
MGVGGSGNPPGTNAKKFAEIVAATVLAGELSLLAALAAGHLAKAHIKLGRGELNRSDSNI
GSKVNP
NT seq 1281 nt   +upstreamnt  +downstreamnt
gtggttgaggggcgtgaccttcgcgaaatagtcgagcgtgtagttaaaggcgaggttaaa
ctacatgagcttgacaagctactgggtaactctaacctagccgcactcgttaggagacta
gcgctcgagaagataacgggcgtaagcctctcatcgataggctcgactatacttgatttc
gaggagcttgttggcaggaacattgagaaccctataggagcagttcaagtgcctgttggc
atcgtaggccctcttagagtgcaaggggagtatgcaaggggagacttctacgtacctctc
gcaacgactgaaggtgcgctagtggcgagtgttaatcgtggtgcaaaagcggtaacgttg
gccggtggcgcaaagactcggatactaagagatggtatgaccagagcgccagtaatatgg
acgccgagcgtcgaggaggctgtcaagctggtaaaatgggtcgaggagaacatagacgtg
ctaaagaaggctgcagagtcgactaccaggcatggcaagctaaagggcctcacgtggtgg
ataacgggcaacctagtatggcttcgttttgaattcgaaaccggcgacgccatgggcatg
aatatggtcaccatagctgtggataaggcgttgcaagaactactcaacaactatgacggt
gatattcgtgttgtggcactaagtggaaacatgtgtgttgacaagaaaccatcaattttg
aacatgctacttgggcgcggtaagaccgtcgtggccgaggcgataataccgcgtgacgtg
gttagggaggtgctgaaaacaactcctgaagctatacatgaggttaacgtggccaagaac
ctcatgggttcggcgagagcaggcagcttgtcgtacaacgcgcattatgctaacattatt
gcagccattttcatagcaactgggcaagacgttgcacaggtggttgagagtagcatgggc
tacacatggaccgaggtgagaaacggcgacttgtacatctcggttacgttaccgagtctg
gaggtcggcacggtagggggtggtacaagactaccgactcagcgcgaggcacttgcacta
atgggcgttgggggttcaggcaaccctccgggcaccaacgccaagaagtttgcagagatt
gtggcggccacggtactagcaggtgaacttagtcttctagcagccttagcggcggggcac
ctggcaaaagcgcacataaaacttggtagaggtgagctaaatcgctcggacagcaacata
ggatccaaggttaacccctag

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (5)   
   KEGG PATHWAY (3)   
   KEGG MODULE (2)   
Chemical substance (6)   
   KEGG COMPOUND (6)   
Chemical reaction (2)   
   KEGG ENZYME (1)   
   KEGG REACTION (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (6)   
   KEGG ORTHOLOGY (1)   
   RefGene (3)   
   NCBI-PROTEINID (1)   
   OC (1)   
Protein sequence (1)   
   UniProt (1)   
Protein domain (1)   
   Pfam (1)   
All databases (24)   

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