KEGG   Propionibacterium freudenreichii subsp. shermanii CIRM-BIA1: PFREUD_22890
Entry
PFREUD_22890      CDS       T01252                                 
Symbol
nadE
Name
(GenBank) Glutamine-dependent NAD(+) synthetase
  KO
K01950  NAD+ synthase (glutamine-hydrolysing) [EC:6.3.5.1]
Organism
pfr  Propionibacterium freudenreichii subsp. shermanii CIRM-BIA1
Pathway
pfr00760  Nicotinate and nicotinamide metabolism
pfr01100  Metabolic pathways
pfr01240  Biosynthesis of cofactors
Module
pfr_M00115  NAD biosynthesis, aspartate => quinolinate => NAD
Brite
KEGG Orthology (KO) [BR:pfr00001]
 09100 Metabolism
  09108 Metabolism of cofactors and vitamins
   00760 Nicotinate and nicotinamide metabolism
    PFREUD_22890 (nadE)
Enzymes [BR:pfr01000]
 6. Ligases
  6.3  Forming carbon-nitrogen bonds
   6.3.5  Carbon-nitrogen ligases with glutamine as amido-N-donor
    6.3.5.1  NAD+ synthase (glutamine-hydrolysing)
     PFREUD_22890 (nadE)
SSDB
Motif
Pfam: NAD_synthase CN_hydrolase
Other DBs
NCBI-ProteinID: CBL57799
UniProt: D7GGY8
Position
2461782..2463908
AA seq 708 aa
MRSIMNFSSLYDQGFARVAAATSNTAIADPATNATRVIEHARRIAATGASVIAFPELCLT
GYAIDDLLLQDTVLDAALDALHTVADATRDLAALIIVGAPLRNGSRLFNCAVVLHHGDVL
GVVPKSYLPTYREFYERRHFADGADQGGVIDLGAHHPATENVGTDHRDANDPGAQAGEGP
SDAADHLVVPFGPDLIFRADDLPDLAVHVEVCEDVWVPVPPSSLAALGGATVLVNISSSP
ITVGKAEQRHLLCRSTSSRNLAAYVYCAAGLGEPTTDLSWDGQTMIYENGRLLAETERFP
TTPGESIADIDLDLLRQERLREGTFDDNARHERPAMRTIGFTLHPPRTDLGLRRPLERFP
FVPSDPARLNQDCYEAYNIQVSALSQRLAAIGGAKVVIGISGGLDSTQALLVAARAMDLA
GRPRTDILTFTMPGFATSAHTRNNAVELSQALGTTFETLDIRPAAEQMLRDLGHPLDDYD
VTYENVQAGLRTDYLFRIANQRGGIVLGTGDLSELALGWATYGVGDQMSHYAVNCGVPKT
LMQHLIRWVIASGQFDDRVGRVLQSILDTEISPELIPVAEGAKPQSTQDTIGPYALHDFA
LYYWLRHGLRLSKIAFLASHIWTDAGLGEWPANFPADERIAYSLADIKKWLTVFCKRFMA
NQFKRTAIPNGPKVMAGGSLSPRGDWRSPSDGNARAWLADLDKVPDQH
NT seq 2127 nt   +upstreamnt  +downstreamnt
atgaggagcatcatgaatttctcgtcgctctacgaccagggcttcgcacgcgtcgccgcc
gcgaccagcaacaccgccatcgccgaccccgccaccaacgccacccgcgtgatcgagcac
gcccggcgcatcgcggccacgggggcatccgtcatcgcgtttccggagctgtgcctcacc
ggctacgcgatcgacgacctcctgctgcaggacaccgtgctcgacgccgccctcgacgcc
ttgcacaccgtggccgacgccacccgcgacctcgccgcgctgatcatcgtcggcgcaccg
ctgcgcaatggttcgcgcctgttcaactgcgcagtcgtcctgcaccacggcgacgtgctg
ggcgtggtgcccaagagctatctgccgacctaccgcgagttctacgagcgccgccacttt
gccgacggcgccgaccagggcggggtcatcgacttgggcgcacaccacccggcaacagag
aacgtggggacagaccaccgggacgccaacgatccgggcgcgcaggccggcgaggggccc
tccgacgccgccgaccacctcgtcgtgcccttcggccctgacctcatcttccgcgccgac
gacctgcccgacctggccgtgcacgtggaggtctgcgaggacgtctgggtgcccgtgccg
cccagttccctggccgccctgggcggcgccaccgtgctggtgaacatctccagctcgccc
atcaccgtgggcaaggccgagcaacgccacctgctgtgccgctcgaccagctcacgcaac
ctcgccgcctacgtctactgcgccgccggcctgggggaacccaccaccgacctgtcgtgg
gacgggcagacgatgatctacgagaacggccgcctgcttgccgaaaccgagcgcttcccc
accaccccgggcgaatcgatcgccgacatcgacctcgacctgctgcgccaggaacggctg
cgcgagggcaccttcgacgacaatgcccgccacgaacgccccgcgatgcgcaccatcggc
ttcaccctgcacccgccccgcaccgatctgggcctgcgtcgtcccctcgaacgcttcccc
ttcgtgccatccgaccccgcacgcctgaaccaggactgctacgaggcctacaacatccag
gtctccgcactgagccagcggctggccgccatcggcggggccaaggtggtgatcggcatc
tcgggtggcctggattccacccaggcgctgctcgtggccgcacgcgccatggaccttgcc
ggacgcccccgcaccgacatcctcaccttcacgatgccgggcttcgccaccagcgcccac
acccgcaacaacgcggtggaactgtcacaggccctcggcaccaccttcgagaccctggac
atccgtcccgccgcggagcagatgctgcgcgatctgggccacccgctcgacgactacgac
gtgacctacgagaacgtccaggccggcctgcgcaccgactacctgttccgcatcgccaac
cagcgcggcggcatcgtgctgggcaccggcgacctgtccgagctcgccctgggctgggcc
acctacggcgtcggcgaccagatgagccactacgccgtgaactgcggagtgcccaagacg
ctgatgcagcacctgatccgttgggtgatcgcctcggggcagttcgacgaccgggtgggg
cgcgtgctccagtcgatcctcgacaccgagatcagccccgagctcatccccgtggccgag
ggcgccaagccgcagagcacccaggacaccatcggcccctatgccctgcacgacttcgcg
ctctactactggctgcgccacggcctgcgtctgtcgaagatcgccttcctggcctcgcac
atctggaccgacgccggcctgggcgagtggccggctaacttccccgcggacgaacggatc
gcctactcgctggccgacatcaagaagtggctcaccgtgttctgcaagcgcttcatggcc
aaccagttcaagcgcaccgccatccccaacggcccgaaggtgatggccggtggttccctg
tcaccacgcggcgactggcgttcgccctccgacggcaatgcccgggcctggctggccgac
ctggacaaggtgcccgaccagcactga

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (5)   
   KEGG PATHWAY (3)   
   KEGG MODULE (2)   
Chemical substance (8)   
   KEGG COMPOUND (8)   
Chemical reaction (2)   
   KEGG ENZYME (1)   
   KEGG REACTION (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (13)   
   KEGG ORTHOLOGY (1)   
   RefGene (10)   
   NCBI-PROTEINID (1)   
   OC (1)   
Protein sequence (1)   
   UniProt (1)   
Protein domain (2)   
   Pfam (2)   
All databases (34)   

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