KEGG   Scheffersomyces stipitis: PICST_68770
Entry
PICST_68770       CDS       T01023                                 
Symbol
LEU4
Name
(RefSeq) 2-isopropylmalate synthase (Alpha-isopropylmalate synthase) (Alpha-IPM synthetase)
  KO
K01649  2-isopropylmalate synthase [EC:2.3.3.13]
Organism
pic  Scheffersomyces stipitis
Pathway
pic00290  Valine, leucine and isoleucine biosynthesis
pic00620  Pyruvate metabolism
pic01100  Metabolic pathways
pic01110  Biosynthesis of secondary metabolites
pic01210  2-Oxocarboxylic acid metabolism
pic01230  Biosynthesis of amino acids
Module
pic_M00432  Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:pic00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00620 Pyruvate metabolism
    PICST_68770 (LEU4)
  09105 Amino acid metabolism
   00290 Valine, leucine and isoleucine biosynthesis
    PICST_68770 (LEU4)
Enzymes [BR:pic01000]
 2. Transferases
  2.3  Acyltransferases
   2.3.3  Acyl groups converted into alkyl groups on transfer
    2.3.3.13  2-isopropylmalate synthase
     PICST_68770 (LEU4)
SSDB
Motif
Pfam: HMGL-like LeuA_dimer SUN
Other DBs
NCBI-GeneID: 4850963
NCBI-ProteinID: XP_001387341
JGI: 68770
UniProt: A3GFB4
Position
1:569514..571337
AA seq 571 aa
MLKDPSTKYAAFKGVKLDKRTWPSKSITKAPRWLSTDLRDGNQALPDPMSVEEKKEYFHK
LLEIGFKEIEVSFPSASQTDFDFTRYAVENAPDDVSIQVLTQSREPLIRRTVESVKGAKK
ATIHTYLATSDVFRDVVFNMSQEDAIAKAIETTKLVKSLTKDDPEMQETEWTLEFSPECF
SDTPTEFAVQICEAVKNVWEPTVENPIIFNLPATVEVASPNVYADQIEYFATHISEREKV
CISLHAHNDRGCGVAASELGLLAGGDRVEGCLFGNGERTGNVDLITVALNMYTNGVAPEL
DFSEIEKLIEVSERCNKIPVHPRAPYSGSLVVCAFSGSHQDAIKKGFSKAEARAARGDTK
WAIPYLPLDPKDIGRNYEAVIRVNSQSGKGGAAWVILRSLGLDLPRHLQVVFSGIVQERA
DSLGRELKSEEIAALFNEQYCSTSNLSVKDFEITKRKNAPENKDREIFAVLQAGSKTVDV
SGQGNGPISAFVDAISKKYGVSFEVVNYSEHSLGSGTQSKAATYIELAYNNSNNEHVTKW
GCGINTDVSQASMEAILSVVNSLIDSKEINL
NT seq 1716 nt   +upstreamnt  +downstreamnt
atgttaaaggatccttccaccaaatatgctgcctttaaaggagtcaagttggacaagaga
acctggccctcaaagtctatcaccaaggctcctaggtggttatctactgatttaagagat
ggtaaccaagcgttgcctgatcccatgtctgtcgaagagaagaaggagtattttcacaag
ctcttggagatcggattcaaagaaatcgaggtatctttcccttctgcatctcaaacagat
tttgacttcaccagatatgctgtggagaacgcaccagatgatgtttcgatccaagttttg
actcagtctagagaacctttgatcagaagaactgttgaatccgtaaagggtgctaagaag
gctaccatacatacatacttggctacttctgacgttttccgtgatgttgttttcaacatg
tcacaagaagatgcaattgccaaagccattgaaactaccaagttggtcaagtctttgaca
aaggacgatccagaaatgcaggaaaccgagtggaccttggaattctctcctgaatgcttc
tcagatactcctaccgaatttgctgtgcaaatttgtgaagcagtcaagaacgtctgggag
ccaactgtagagaatcctatcattttcaacttgccagctaccgttgaagttgcttctcca
aacgtctacgctgaccagatcgaatactttgctacccacatttccgaacgtgaaaaggtg
tgtatttctcttcatgctcacaatgaccgtggctgcggtgttgctgcctcggaattaggt
ttattggctggcggagacagagtcgaaggttgtttgtttggaaacggtgaaagaaccggt
aacgtagacttgatcactgttgctctcaacatgtacaccaatggagttgcaccggagttg
gacttttcagaaatcgaaaagctcatcgaggtcagtgaaagatgtaacaaaatcccagtt
cacccaagagctccatactctggatccttggtcgtttgtgccttctctggttctcaccaa
gatgctatcaagaagggattctccaaggctgaagccagagctgctaggggtgacaccaaa
tgggccattccatacttgccattagaccctaaggatatcggtagaaactacgaggccgtt
atcagagtcaactctcaatctggtaagggaggtgctgcctgggtcatcttgagatctctc
ggcttggacttgccaagacacttgcaagttgtcttttctggtattgttcaggaaagagct
gactctttgggtagagaattgaagtctgaagagattgccgctttgttcaacgagcagtac
tgctctacttccaacttgtctgtcaaggacttcgagataactaagagaaagaatgctcca
gagaacaaggaccgtgagatctttgctgtcttgcaggctggatccaagaccgttgacgtc
agtggacaaggtaacggacctatttcggcctttgtggatgccatatccaagaaatacggt
gtttcctttgaagtcgtcaactacagtgaacacagtttaggcagtggtacccagagtaag
gctgctacttacattgagttagcctacaacaactctaacaacgagcatgttacaaagtgg
ggatgcggcattaacacagatgtgtcgcaggcttcgatggaggccattctttctgttgtg
aactcattgattgatagcaaggaaattaatttgtag

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (7)   
   KEGG PATHWAY (6)   
   KEGG MODULE (1)   
Chemical substance (5)   
   KEGG COMPOUND (5)   
Chemical reaction (2)   
   KEGG ENZYME (1)   
   KEGG REACTION (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (5)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   JGI (1)   
   OC (1)   
Protein sequence (2)   
   UniProt (1)   
   RefSeq(pep) (1)   
DNA sequence (1)   
   RefSeq(nuc) (1)   
Protein domain (3)   
   Pfam (3)   
All databases (28)   

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