KEGG   Pirellula sp. SH-Sr6A: VN12_00795
Entry
VN12_00795        CDS       T04360                                 
Symbol
leuA_1
Name
(GenBank) 2-isopropylmalate synthase
  KO
K01649  2-isopropylmalate synthase [EC:2.3.3.13]
Organism
pir  Pirellula sp. SH-Sr6A
Pathway
pir00290  Valine, leucine and isoleucine biosynthesis
pir00620  Pyruvate metabolism
pir01100  Metabolic pathways
pir01110  Biosynthesis of secondary metabolites
pir01210  2-Oxocarboxylic acid metabolism
pir01230  Biosynthesis of amino acids
Module
pir_M00432  Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:pir00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00620 Pyruvate metabolism
    VN12_00795 (leuA_1)
  09105 Amino acid metabolism
   00290 Valine, leucine and isoleucine biosynthesis
    VN12_00795 (leuA_1)
Enzymes [BR:pir01000]
 2. Transferases
  2.3  Acyltransferases
   2.3.3  Acyl groups converted into alkyl groups on transfer
    2.3.3.13  2-isopropylmalate synthase
     VN12_00795 (leuA_1)
SSDB
Motif
Pfam: HMGL-like LeuA_dimer Gemini_AL2
Other DBs
NCBI-ProteinID: AMV30620
UniProt: A0A142XVR0
Position
240373..241944
AA seq 523 aa
MTKRAVHIYDTTLRDGTQGEGVSLSLQDKLNIAERLAEFGIDMIEGGYPLSNEKDAMFFR
KVKQLKLGNSLVSAFGMTRRRGLAAADDPGMKALVAAETPVITVVGKSWDFHATEVLGVS
LQENVDMIAESVEFLGRHAQVVYDAEHFFDGYKANREYALQAVSAAAKAGAQWIVFCDTN
GGTLPEEIAAIVSDAKSILAPLGVRMGIHCHNDGDLATANSLAAIDAGCDQVQGTINGIG
ERCGNADLVAIMANLQYKKTGYSVLDGRPLDHLTELSRYVYETANLQLRSGQPFVGRSAF
AHKGGMHVHAVNKFAHTYEHMDPAKIGNERRILVSELSGRSNIAALMQDSGLPADRATQD
RILAEIVSKENQGYQFEAAEGSFELLVKKCTGSYQPHFETIKYQVLAGDIQAQTAEAYAE
AILKVQVQGTVRVEAAEGHGPVNAMDAALRKALLPSFPQLDSMRLVDFKVRVVNGEAGTA
ARIRVNIESADDQKTWRTIGVSENIIEASWQALVDAFECKLHR
NT seq 1572 nt   +upstreamnt  +downstreamnt
atgaccaaacgcgctgttcacatctacgacacaacccttcgcgatggcacccaaggggag
ggagtgagcctttccctccaagacaaactcaacatcgccgaacggcttgcggaatttggg
atcgacatgatcgaagggggctaccccctctccaacgagaaggacgcgatgttctttcgc
aaggtcaaacagctgaaacttggaaatagcctggtctccgccttcggcatgacccgccgt
cgcggattggccgcggcggacgaccccggtatgaaggcgctcgttgccgccgaaacaccc
gtcatcaccgtggtcggcaagtcgtgggactttcacgccaccgaagtgctgggggtctcc
cttcaagagaacgtggacatgatcgccgaaagcgtcgaattcctcggccgccacgcgcaa
gtcgtctacgatgcggaacattttttcgacggctacaaagccaaccgcgaatacgctctc
caagcggtctcggcggcagccaaagcgggcgcccaatggatcgtcttctgcgataccaat
ggtggcacccttcccgaggaaatcgcagcaatcgtctccgatgcgaaatcgatcctcgcc
cctctcggcgttcgcatggggatccattgtcacaacgatggcgacctagcgaccgcgaat
tccttggcagccatcgatgctgggtgcgatcaagtccaagggaccatcaatggcatcggc
gaacgttgcggaaatgccgaccttgtggccatcatggcaaacctgcagtacaagaagacg
ggttacagcgttctcgacggccgtcccctcgatcacttgacggaactttcccgatacgtg
tacgagacggccaacctccaactccggagcggacagccctttgtcgggcgaagtgcattc
gcgcacaaaggtggaatgcacgtccacgctgtcaataaattcgcccatacctacgaacac
atggatccggccaagattggaaacgaacgccgcatcctcgtcagcgaactctccggtcga
tccaacatagctgccttgatgcaggactccggccttcctgcggatcgtgcgacccaagac
cgaatcttggccgagatcgtttccaaagagaaccaaggctatcagttcgaagccgccgaa
ggctcctttgaattgctggtcaaaaagtgcaccggttcctaccagcctcatttcgaaacg
atcaaataccaagttctggcgggggatatccaagcccaaacggcagaagcctacgccgaa
gcgattctcaaagtgcaagtgcaagggacggtgcgggtcgaagcggccgaagggcatggt
ccggtcaatgcaatggatgccgcccttcgcaaggcattgctaccctccttcccgcaactc
gactccatgcgattggtcgatttcaaagtgcgagtggtaaacggagaggccggcaccgct
gcccgcatccgcgtgaacatcgagagcgccgacgaccagaagacatggcgaaccatcggg
gtaagcgagaacatcatcgaagcgagctggcaagccctcgtggatgcattcgaatgcaaa
ctccatcgctaa

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (7)   
   KEGG PATHWAY (6)   
   KEGG MODULE (1)   
Chemical substance (5)   
   KEGG COMPOUND (5)   
Chemical reaction (2)   
   KEGG ENZYME (1)   
   KEGG REACTION (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (3)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   OC (1)   
Protein sequence (1)   
   UniProt (1)   
Protein domain (3)   
   Pfam (3)   
All databases (24)   

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