KEGG   Plantactinospora sp. KBS50: CIK06_27355
Entry
CIK06_27355       CDS       T05048                                 
Symbol
leuA
Name
(GenBank) 2-isopropylmalate synthase
  KO
K01649  2-isopropylmalate synthase [EC:2.3.3.13]
Organism
plk  Plantactinospora sp. KBS50
Pathway
plk00290  Valine, leucine and isoleucine biosynthesis
plk00620  Pyruvate metabolism
plk01100  Metabolic pathways
plk01110  Biosynthesis of secondary metabolites
plk01210  2-Oxocarboxylic acid metabolism
plk01230  Biosynthesis of amino acids
Module
plk_M00432  Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:plk00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00620 Pyruvate metabolism
    CIK06_27355 (leuA)
  09105 Amino acid metabolism
   00290 Valine, leucine and isoleucine biosynthesis
    CIK06_27355 (leuA)
Enzymes [BR:plk01000]
 2. Transferases
  2.3  Acyltransferases
   2.3.3  Acyl groups converted into alkyl groups on transfer
    2.3.3.13  2-isopropylmalate synthase
     CIK06_27355 (leuA)
SSDB
Motif
Pfam: HMGL-like LeuA_dimer
Other DBs
NCBI-ProteinID: ASW57070
UniProt: A0A248YU36
Position
6316095..6317909
AA seq 604 aa
MASSATAPETSDAAPAGADPSVTADPRPGTDPIARQRGSGMPFRRYRPYQQQFAIDLPDR
QWPTRRISHAPRWCAVDLRDGNQALIDPMSPERKRRMFQLLVRMGYKEIEVGFPSASQAD
FDFVRQLIEQDLIPDDVTIQVITQCREHLIDRTFESLRGAGRAIVHFYNSTSILQRRVVF
GLDRAGITDIATSAARLCRKYAELHTPDTDIYYEYSPESYTGTELEYAVEICAAVTEAID
PTPDRPLIMNLPATVEMATPNVYADSIEWMHRNLPRRQSLVLSLHPHNDRGTGVAAAELG
LLAGADRVEGCLFGNGERTGNVDLVTLGLNLFSQGIDPEIDFSGIDEIKRAVEYCNQLPV
HERHPYAGDLVFTAFSGSHQDAINKGLDALRAEATAAGVPVGAHPWEVPYLPVDPKDLGR
TYEAIIRVNSQSGKGGVAYIMKAEHHLDLPRRLQIEFSGVVQRVTDAGGGEVEPDRMWEI
FATDYLVDHQPAPAVVVHRYSTATIEGKVEIDVEVSTGGTRRSLSATGTGPIDAYVNALA
ELDIQARVLDYHEHAMSAGGDAQAAAYVECDVDGRPVWGVGLDANIVTASIRAVTSAVNR
ARRA
NT seq 1815 nt   +upstreamnt  +downstreamnt
atggcctcttccgccaccgcgcccgaaaccagcgacgccgcgcccgcgggcgccgatccc
tcggtgaccgccgacccgcgcccgggcaccgatcccatcgcccgccagcgcggcagcggc
atgccgttccgccgctaccggccctaccagcaacagttcgcgatcgacctgccggaccgg
cagtggcccacccgccggatcagccacgcaccgcgctggtgcgccgtcgacctgcgggac
ggcaaccaggcgctgatcgacccgatgtcgccggagcgcaagcggcggatgttccagctg
ctcgtccggatgggatacaaggagatcgaggtcggcttcccctccgccagccaggccgac
ttcgacttcgtccggcagctcatcgagcaggacctgatcccggacgacgtgacgatccag
gtcatcacccagtgccgcgagcacctgatcgaccgcaccttcgagtcgctgcgcggcgcc
ggccgggccatcgtgcacttctacaactcgacctcgatcctccagcgccgcgtcgtgttc
gggctggaccgcgcggggatcaccgacatcgccacctcggccgcgcggctctgccgcaag
tacgccgagctgcacacccccgacaccgacatctactatgagtactcccccgagtcgtac
acgggcaccgagttggagtacgcggtcgagatctgcgcggcggtgaccgaggcgatcgac
cccaccccggaccgtccgctgatcatgaacctgccggccaccgtcgagatggccacgccg
aacgtgtacgccgactcgatcgagtggatgcaccgcaacctgccccgccggcagagcctg
gtgctcagcctgcacccgcacaacgaccggggcaccggggtcgcggcggccgagctgggc
ctgctggccggcgccgaccgggtcgagggctgcctgttcggcaacggcgaacggaccggc
aacgtcgacctggtgaccctcgggctcaacctgttctcccagggcatcgaccccgagatc
gacttctccgggatcgacgagatcaagcgggcggtcgagtactgcaaccagctgccggtg
cacgagcggcacccgtacgccggcgacctcgtcttcaccgccttctccggctcccaccag
gacgccatcaacaagggcctggacgcgctgcgggccgaggcgaccgcggccggcgtaccg
gtcggcgcgcacccgtgggaggtgccgtacctgccggtcgacccgaaggacctgggccgc
acctacgaggcgatcatccgggtcaactcgcagtccggcaagggcggcgtcgcgtacatc
atgaaggccgagcaccacctcgacctgccgcgccggctccagatcgagttctccggagtc
gtgcagcgggtgaccgacgccggcggcggcgaggtcgagccggaccggatgtgggagatc
ttcgccaccgactacctggtcgaccaccagcccgcccccgcggtcgtcgtgcaccggtac
agcacggccaccatcgagggcaaggtggagatcgacgtggaggtgtccaccgggggcacc
cggcggtcgctctcggccaccggcaccggcccgatcgacgcgtacgtcaacgccctcgcc
gagctggacatccaggcccgggtgctggattaccacgagcacgcgatgtccgcgggcggg
gacgcccaggcggccgcgtacgtcgagtgcgacgtggacggacgcccggtctggggcgtc
ggcctggacgccaacatcgtcacggcgtccatccgcgccgtcaccagcgccgtgaaccgc
gcccgccgggcctga

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (7)   
   KEGG PATHWAY (6)   
   KEGG MODULE (1)   
Chemical substance (5)   
   KEGG COMPOUND (5)   
Chemical reaction (2)   
   KEGG ENZYME (1)   
   KEGG REACTION (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (12)   
   KEGG ORTHOLOGY (1)   
   RefGene (9)   
   NCBI-PROTEINID (1)   
   OC (1)   
Protein sequence (1)   
   UniProt (1)   
Protein domain (2)   
   Pfam (2)   
All databases (32)   

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