KEGG   Pongo abelii (Sumatran orangutan): 100447447
Entry
100447447         CDS       T01416                                 
Symbol
EZH2
Name
(RefSeq) histone-lysine N-methyltransferase EZH2 isoform X1
  KO
K11430  [histone H3]-lysine27 N-trimethyltransferase EZH2 [EC:2.1.1.356]
Organism
pon  Pongo abelii (Sumatran orangutan)
Pathway
pon00310  Lysine degradation
pon01100  Metabolic pathways
pon03083  Polycomb repressive complex
pon05206  MicroRNAs in cancer
Brite
KEGG Orthology (KO) [BR:pon00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00310 Lysine degradation
    100447447 (EZH2)
 09120 Genetic Information Processing
  09126 Chromosome
   03083 Polycomb repressive complex
    100447447 (EZH2)
 09160 Human Diseases
  09161 Cancer: overview
   05206 MicroRNAs in cancer
    100447447 (EZH2)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03036 Chromosome and associated proteins [BR:pon03036]
    100447447 (EZH2)
Enzymes [BR:pon01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.356  [histone H3]-lysine27 N-trimethyltransferase
     100447447 (EZH2)
Chromosome and associated proteins [BR:pon03036]
 Eukaryotic type
  Histone modification proteins
   HMTs (histone methyltransferases)
    HKMTs (histone lysine methyltransferases)
     100447447 (EZH2)
   Polycomb repressive complex (PRC) and associated proteins
    PRC2.1
     100447447 (EZH2)
    PRC2.2
     100447447 (EZH2)
SSDB
Motif
Pfam: Ezh2_MCSS PRC2_HTH_1 SET EZH2_WD-Binding preSET_CXC
Other DBs
NCBI-GeneID: 100447447
NCBI-ProteinID: XP_024105767
Position
7:complement(134887205..134963330)
AA seq 751 aa
MGQTGKKSEKGPVCWRKRVKSEYMRLRQLKRFRRADEVKSMFSSNRQKILERTEILNQEW
KQRRIQPVHILTSVSSLRGTRECSVTSDLDFPTQVIPLKTLNAVASVPIMYSWSPLQQNF
MVEDETVLHNIPYMGDEVLDQDGTFIEELIKNYDGKVHGDRECGFINDEIFVELVNALGQ
YNDDDDDDDGDDPEEREEKQKDLEDHRDDKESRPPRKFPSDKIFEAISSMFPDKGTAEEL
KEKYKELTEQQLPGALPPECTPNIDGPNAKSVQREQSLHSFHTLFCRRCFKYDCFLHRKC
NYSFHATPNTYKRKNTETALDNKPCGPQCYQHLEGAKEFAAALTAERIKTPPKRPGGRRR
GRLPNNSSRPSTPTINVLESKDTDSDREAGTETGGENNDKEEEEKKDETSSSSEANSRCQ
TPIKMKPNIEPPENVEWSGAEASMFRVLIGTYYDNFCAIARLIGTKTCRQVYEFRVKESS
IIAPAPAEDVDTPPRKKKRKHRLWAAHCRKIQLKKDGSSNHVYNYQPCDHPRQPCDSSCP
CVIAQNFCEKFCQCSSECQNRFPGCRCKAQCNTKQCPCYLAVRECDPDLCLTCGAADHWD
SKNVSCKNCSIQRGSKKHLLLAPSDVAGWGIFIKDPVQKNEFISEYCGEIISQDEADRRG
KVYDKYMCSFLFNLNNDFVVDATRKGNKIRFANHSVNPNCYAKVMMVNGDHRIGIFAKRA
IQTGEELFFDYRYSQADALKYVGIEREMEIP
NT seq 2256 nt   +upstreamnt  +downstreamnt
atgggccagactgggaagaaatctgagaagggaccagtttgttggcggaagcgtgtaaaa
tcagagtacatgcgactgagacagctcaagaggttcagacgggctgatgaagtaaagagt
atgtttagttccaatcgtcagaaaattttggaaagaacggaaatcttaaaccaagaatgg
aaacagcgaaggatacagcctgtgcacatcctgacttctgtgagctcattgcgcgggact
agggagtgttcggtgaccagtgacttggattttccaacacaagtcatcccattaaagact
ctgaatgcagttgcttcagtgcccataatgtattcttggtctcccctacagcagaatttt
atggtggaagatgaaactgttttacataacattccttatatgggagatgaagttttagac
caggatggtactttcattgaagaactaataaaaaattatgatggaaaagtacatggggat
agagaatgtgggtttataaatgatgaaatttttgtggagttggtgaatgcccttggtcaa
tataatgatgatgacgatgacgatgatggagacgatcctgaagaaagagaagaaaagcag
aaagatctggaggatcaccgagatgataaagaaagccgcccacctcggaaatttccttct
gataaaatttttgaagccatttcctcaatgtttccagataagggcacagcagaagaacta
aaggaaaaatataaagaactcaccgaacagcagctcccaggcgcacttcctcctgaatgt
acccccaacatagatggaccaaacgctaaatctgttcagagagagcaaagcttacactcc
tttcatacgcttttctgtaggcgatgttttaaatatgactgcttcctacatcgtaagtgc
aattattcctttcatgcaacacccaacacttataagcggaagaacacagaaacagctcta
gacaacaaaccttgtggaccacagtgttaccagcatttggagggagcaaaggagttcgct
gctgctctcaccgctgagcggataaagaccccaccaaaacgcccaggaggccgcagaaga
ggacggcttcccaataacagtagcaggcccagcacccccaccattaatgtgctggaatca
aaggatacagacagtgatagggaagcagggactgaaacggggggagagaacaatgataaa
gaagaagaagagaagaaagatgaaacttcgagctcctctgaagcaaattctcggtgtcaa
acaccaataaagatgaagccaaatattgaacctcctgagaatgtggagtggagtggtgct
gaagcctcaatgtttagagtcctcattggcacttactatgacaatttctgtgccattgct
aggttaattgggaccaaaacatgtagacaggtgtatgagtttagagtcaaagaatctagc
atcatagctccagctcccgctgaggatgtggatactcctccaaggaaaaagaagaggaaa
caccggttgtgggctgcgcactgcagaaagatacagctgaaaaaggacggctcctctaac
catgtttacaactatcaaccctgtgatcatccacggcagccttgtgacagttcgtgccct
tgtgtgatagcacaaaatttttgtgaaaagttttgtcaatgtagttcagagtgtcaaaac
cgctttccgggatgccgctgcaaagcacagtgcaacaccaagcagtgcccgtgctacctg
gctgtccgagagtgtgaccctgacctctgtcttacttgtggagccgctgaccattgggac
agtaaaaatgtgtcctgcaagaactgcagtattcagcggggctccaaaaagcatctattg
ctggcaccatctgatgtggcaggctgggggatttttatcaaagatcctgtgcagaaaaat
gaattcatctcagaatactgtggagagattatttctcaagatgaagctgacagaagaggg
aaagtatatgataaatacatgtgcagctttctgttcaacttgaacaatgattttgtggtg
gatgcaacccgcaagggtaacaaaattcgttttgcaaatcattcagtaaatccaaactgc
tatgcaaaagttatgatggttaacggtgatcacaggataggtatttttgccaagagagcc
atccagactggcgaagagctgttttttgattacagatacagccaggctgatgccctgaag
tatgtcggcatcgaaagagaaatggaaatcccttga

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Ontology (3)   
   KEGG BRITE (3)   
Pathway (4)   
   KEGG PATHWAY (4)   
Chemical substance (6)   
   KEGG COMPOUND (6)   
Chemical reaction (4)   
   KEGG ENZYME (1)   
   KEGG REACTION (3)   
Genome (1)   
   KEGG GENOME (1)   
Gene (4)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   OC (1)   
Protein sequence (17)   
   RefSeq(pep) (17)   
DNA sequence (17)   
   RefSeq(nuc) (17)   
Protein domain (5)   
   Pfam (5)   
All databases (61)   

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