KEGG   Pongo abelii (Sumatran orangutan): 100447782Help
Entry
100447782         CDS       T01416                                 

Gene name
UGT2A1
Definition
(RefSeq) UDP-glucuronosyltransferase 2A1 isoform X1
  KO
K00699  glucuronosyltransferase [EC:2.4.1.17]
Organism
pon  Pongo abelii (Sumatran orangutan)
Pathway
pon00040  Pentose and glucuronate interconversions
pon00053  Ascorbate and aldarate metabolism
pon00140  Steroid hormone biosynthesis
pon00830  Retinol metabolism
pon00860  Porphyrin and chlorophyll metabolism
pon00980  Metabolism of xenobiotics by cytochrome P450
pon00982  Drug metabolism - cytochrome P450
pon00983  Drug metabolism - other enzymes
pon01100  Metabolic pathways
pon05204  Chemical carcinogenesis
Module
pon_M00014  Glucuronate pathway (uronate pathway)
Brite
KEGG Orthology (KO) [BR:pon00001]
 Metabolism
  Carbohydrate metabolism
   00040 Pentose and glucuronate interconversions
    100447782 (UGT2A1)
   00053 Ascorbate and aldarate metabolism
    100447782 (UGT2A1)
  Lipid metabolism
   00140 Steroid hormone biosynthesis
    100447782 (UGT2A1)
  Metabolism of cofactors and vitamins
   00830 Retinol metabolism
    100447782 (UGT2A1)
   00860 Porphyrin and chlorophyll metabolism
    100447782 (UGT2A1)
  Xenobiotics biodegradation and metabolism
   00980 Metabolism of xenobiotics by cytochrome P450
    100447782 (UGT2A1)
   00982 Drug metabolism - cytochrome P450
    100447782 (UGT2A1)
   00983 Drug metabolism - other enzymes
    100447782 (UGT2A1)
 Human Diseases
  Cancers
   05204 Chemical carcinogenesis
    100447782 (UGT2A1)
Enzymes [BR:pon01000]
 2. Transferases
  2.4  Glycosyltransferases
   2.4.1  Hexosyltransferases
    2.4.1.17  glucuronosyltransferase
     100447782 (UGT2A1)
Glycosyltransferases [BR:pon01003]
 Others
  Hydrophobic molecule
   100447782 (UGT2A1)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: UDPGT Glyco_tran_28_C Pro_3_hydrox_C
Motif
Other DBs
NCBI-GeneID: 100447782
NCBI-ProteinID: XP_002814863
Ensembl: ENSPPYG00000014790
UniProt: H2PDG7
Position
4
AA seq 527 aa AA seqDB search
MLNNLLLFSLQISLIGTTLGGNVLIWPMEGSHWLNVKIIIDELIKKEHNVTVLVASGALF
ITPTSNPSLTFEIYKVPFGKEKIEGVIKDFVLTWLENRPSPSTIWRFYQEMAKVIKDFHI
VSQEICDGVLKNQQLMEKLKKSKFEVLVSDPVFPCGDIVALKLGIPFMYSLRFSPASTVE
KHCGKVPYPPSYVPAVLSELTDQMSFTDRIRNFISYHLQDYMFETLWKSWDSYYSKALGR
PTTLCETMGKAEIWLIRTYWDFEFPRPYLPNFEFVGGLHCKPAKPLPKEMEEFIQSSGKD
GVVVFSLGSMVKNLTEEKANLIASALAQIPQKVLWRYKGKKPATLGNNTQLYDWIPQNDL
LGHPKTKAFITHGGTNGIYEAIYHGVPMVGVPMFADQPDNIAHMKAKGAAVEVNLNTMTS
VDLLSALRTVINEPSYKENAMRLSRIHHDQPVKPLDRAVFWIEFVMRHKGAKHLRPAAHD
LNWFQYHSLDVIGFLLVCVTTAIFLVIQCCLFSCQKFGKIGKKKKRE
NT seq 1584 nt NT seq  +upstreamnt  +downstreamnt
atgttaaacaaccttctgctgttctcccttcagataagtctcataggaaccactcttggt
gggaatgttttgatttggccaatggaaggtagtcattggctaaatgttaagataattata
gatgagctcattaaaaaggagcataatgtgactgtcctagttgcctctggtgcacttttc
atcacaccaacctctaacccatctctgacatttgaaatatataaggtgccctttggcaaa
gaaaaaatagaaggagtaattaaggactttgttttgacatggctggaaaatagaccatct
ccttcaaccatttggagattctatcaggagatggccaaagtaatcaaggacttccacata
gtgtctcaggagatctgtgatggcgttcttaaaaaccaacagctgatggaaaagctaaag
aaaagcaagtttgaagtcctggtgtccgatccagtatttccttgtggcgatatagtagct
ttaaaacttggaattccatttatgtactccttgaggttttctccagcctcaacagtggaa
aagcactgtgggaaggtaccataccctccttcctatgttcctgctgttttatcagaactc
accgaccaaatgtctttcactgacagaataagaaatttcatctcctaccacctacaggac
tacatgtttgaaactctttggaaatcatgggattcatactatagtaaagctttaggaaga
cccactacattatgtgagactatggggaaagctgaaatttggttaatccgaacatattgg
gattttgaatttcctcgtccatacttacctaattttgagttcgttggaggattgcactgc
aaacctgccaaacctttacctaaggaaatggaagaattcatccagagctcaggtaaagat
ggtgttgtggtgttttctctgggatcaatggtcaaaaaccttacagaagaaaaggccaat
cttattgcctcagctcttgcccagattccacagaaggttttatggagatacaaaggaaag
aaaccagccacattaggaaacaatacgcagctctatgattggataccccagaatgatctt
cttggtcatcccaaaaccaaagcttttatcactcatggtggaactaatgggatctatgaa
gctatttaccacggagtccctatggtgggagttcccatgtttgctgatcagcctgataac
attgctcatatgaaggccaaaggagcagctgtggaagtgaacctaaacacaatgacaagt
gtggatttgcttagcgctttgagaacagtcattaatgaaccttcttataaagagaatgct
atgaggttatcaagaattcaccatgatcaacctgtaaagcccctggatcgagcagtcttc
tggatcgagtttgtcatgcgccacaaaggagccaagcacctgcggccagctgcccacgac
ctcaactggttccagtaccactctttggatgtaattgggttcttgctggtctgtgtgaca
acagctatatttttggtcatacaatgttgtttgttttcctgtcaaaaatttggtaagata
ggaaagaagaaaaaaagagaatag

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