KEGG   Pongo abelii (Sumatran orangutan): 100455257
Entry
100455257         CDS       T01416                                 
Symbol
TXNRD2
Name
(RefSeq) thioredoxin reductase 2, mitochondrial
  KO
K22182  thioredoxin reductase (NADPH) [EC:1.8.1.9]
Organism
pon  Pongo abelii (Sumatran orangutan)
Pathway
pon00450  Selenocompound metabolism
pon05200  Pathways in cancer
pon05225  Hepatocellular carcinoma
Brite
KEGG Orthology (KO) [BR:pon00001]
 09100 Metabolism
  09106 Metabolism of other amino acids
   00450 Selenocompound metabolism
    100455257 (TXNRD2)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    100455257 (TXNRD2)
  09162 Cancer: specific types
   05225 Hepatocellular carcinoma
    100455257 (TXNRD2)
Enzymes [BR:pon01000]
 1. Oxidoreductases
  1.8  Acting on a sulfur group of donors
   1.8.1  With NAD+ or NADP+ as acceptor
    1.8.1.9  thioredoxin-disulfide reductase
     100455257 (TXNRD2)
SSDB
Motif
Pfam: Pyr_redox_2 Pyr_redox_dim Pyr_redox FAD_binding_2 Pyr_redox_3 DAO AlaDh_PNT_C FAD_oxidored GIDA HI0933_like NAD_binding_8 Thi4 Lys_Orn_oxgnase Lycopene_cycl FAD_binding_3
Other DBs
NCBI-GeneID: 100455257
NCBI-ProteinID: NP_001243401
Ensembl: ENSPPYG00000011587
Position
22:6027256..6093711
AA seq 524 aa
MAAMAVALRGLGGRFRWRTQAVAGGVRGAARGAAAGQRDYDLLVVGGGSGGLACAKEAAQ
LGRKVAVVDYVEPSPQGTRWGLGGTCVNVGCIPKKLMHQAALLGGLIQDAPHYGWEVAQP
VLHDWRKMAEAVQNHVKSLNWGHRVQLQDRKVKYFNIKASFVDEHTVCGVAKGGKEILLS
ADHIIIATGGRPRYPTHIEGALEYGITSDDIFWLKESPGKTLVVGASYVALECAGFLTGI
GLDTTIMMRSIPLRGFDQQMSSLVIEHMASHGTRFLRGCAPSRVRRLPDGQLQVTWEDRA
TGKEDMGTFDTVLWAIGRVPDTRSLNLEKAGVDTSPDTQKILVDSREATSVPHIYAIGDV
VEGRPELTPTAIMAGRLLVQRLFGGSSDLMDYDNVPTTVFTPLEYGCVGLSEEEAVARHG
QEHVEVYHAHYKPLEFTVAGRDASQCYVKMVCLREPPQLLLGLHFLGPNAGEVTQGFALG
IKCGASYAQVMRTVGIHPTCSEEVVKLRISKRSGLDPTVTGCUG
NT seq 1575 nt   +upstreamnt  +downstreamnt
atggcggcgatggcggtggcgctgcggggattaggagggcgcttccggtggcggacgcag
gccgtggcgggcggggtgcggggcgcggcgcggggcgcagcagcaggtcagcgggactat
gatctcctggtggtcggcgggggatctggcggcttggcttgtgccaaggaggccgctcag
ctgggaaggaaggtggccgtggtggactacgtggaaccttctccccaaggcacccggtgg
ggcctcggcggcacctgcgtcaacgtgggctgcatccccaagaagctgatgcaccaggcg
gcactgctggggggactgatccaagatgccccccactatggctgggaggtggcccagccc
gtgctgcatgactggaggaagatggcagaagctgttcaaaatcacgtgaaatccttgaac
tggggccaccgtgtccagcttcaggacagaaaagtcaagtactttaacatcaaagccagc
tttgttgacgagcacacggtttgtggcgttgccaaaggtgggaaagagattctgctatca
gctgaccacatcatcattgctactggagggcggccgagataccccacgcacatcgaaggt
gccttggaatatggaatcacaagtgatgacatcttctggctgaaggaatcccctggaaaa
acgttggtggttggggccagctatgtggccctggagtgtgctggcttcctcaccgggatt
gggctggacaccaccatcatgatgcgcagcatccccctccgcggctttgaccagcaaatg
tcctccttggtcatagagcacatggcatctcatggcacccggttcctgaggggctgtgcc
ccctcccgggtcaggaggctccctgatggccagctgcaggtcacctgggaggaccgcgcc
accggcaaggaggacatgggcaccttcgacaccgtcctgtgggccataggtcgagtccca
gacaccagaagtctgaatttggagaaggctggggtagatactagccccgacactcagaag
atcctggtggactcccgggaagccacctctgtgccccacatctacgccattggtgacgtg
gtggaggggcggcctgagctgacacccacagcgatcatggccgggaggctcctggtgcag
cggctcttcggcgggtcctcagatctgatggactacgacaatgttcccacgaccgtcttc
accccgctggagtatggctgtgtggggctgtccgaggaggaggcagtggctcgccacggg
caggagcatgttgaggtctatcacgcccattataaaccactggagttcacggtggctgga
cgggatgcatcccagtgttatgtaaagatggtgtgcctgagggagcccccgcagctgctg
ctgggcctgcacttcctcggccccaacgcaggcgaagttactcaaggatttgctctgggg
atcaagtgtggggcctcctatgcgcaggtgatgcggaccgtgggtatccatcccacatgc
tctgaggaggtagtcaagctgcgcatctccaagcgctcaggcctggaccccacggtgaca
ggctgctgagggtaa

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (3)   
   KEGG PATHWAY (3)   
Chemical substance (8)   
   KEGG COMPOUND (8)   
Chemical reaction (3)   
   KEGG ENZYME (1)   
   KEGG REACTION (2)   
Genome (1)   
   KEGG GENOME (1)   
Gene (5)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
Protein sequence (1)   
   RefSeq(pep) (1)   
DNA sequence (1)   
   RefSeq(nuc) (1)   
Protein domain (15)   
   Pfam (15)   
All databases (39)   

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