KEGG   Pongo abelii (Sumatran orangutan): 100459692
Entry
100459692         CDS       T01416                                 
Symbol
ATP2A2
Name
(RefSeq) sarcoplasmic/endoplasmic reticulum calcium ATPase 2
  KO
K05853  P-type Ca2+ transporter type 2A [EC:7.2.2.10]
Organism
pon  Pongo abelii (Sumatran orangutan)
Pathway
pon04020  Calcium signaling pathway
pon04022  cGMP-PKG signaling pathway
pon04024  cAMP signaling pathway
pon04148  Efferocytosis
pon04260  Cardiac muscle contraction
pon04261  Adrenergic signaling in cardiomyocytes
pon04380  Osteoclast differentiation
pon04919  Thyroid hormone signaling pathway
pon04972  Pancreatic secretion
pon05010  Alzheimer disease
pon05017  Spinocerebellar ataxia
pon05022  Pathways of neurodegeneration - multiple diseases
pon05410  Hypertrophic cardiomyopathy
pon05412  Arrhythmogenic right ventricular cardiomyopathy
pon05414  Dilated cardiomyopathy
pon05415  Diabetic cardiomyopathy
Brite
KEGG Orthology (KO) [BR:pon00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04020 Calcium signaling pathway
    100459692 (ATP2A2)
   04024 cAMP signaling pathway
    100459692 (ATP2A2)
   04022 cGMP-PKG signaling pathway
    100459692 (ATP2A2)
 09140 Cellular Processes
  09141 Transport and catabolism
   04148 Efferocytosis
    100459692 (ATP2A2)
 09150 Organismal Systems
  09152 Endocrine system
   04919 Thyroid hormone signaling pathway
    100459692 (ATP2A2)
  09153 Circulatory system
   04260 Cardiac muscle contraction
    100459692 (ATP2A2)
   04261 Adrenergic signaling in cardiomyocytes
    100459692 (ATP2A2)
  09154 Digestive system
   04972 Pancreatic secretion
    100459692 (ATP2A2)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    100459692 (ATP2A2)
 09160 Human Diseases
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    100459692 (ATP2A2)
   05017 Spinocerebellar ataxia
    100459692 (ATP2A2)
   05022 Pathways of neurodegeneration - multiple diseases
    100459692 (ATP2A2)
  09166 Cardiovascular disease
   05410 Hypertrophic cardiomyopathy
    100459692 (ATP2A2)
   05412 Arrhythmogenic right ventricular cardiomyopathy
    100459692 (ATP2A2)
   05414 Dilated cardiomyopathy
    100459692 (ATP2A2)
   05415 Diabetic cardiomyopathy
    100459692 (ATP2A2)
Enzymes [BR:pon01000]
 7. Translocases
  7.2  Catalysing the translocation of inorganic cations
   7.2.2  Linked to the hydrolysis of a nucleoside triphosphate
    7.2.2.10  P-type Ca2+ transporter
     100459692 (ATP2A2)
SSDB
Motif
Pfam: E1-E2_ATPase Cation_ATPase_C Cation_ATPase Cation_ATPase_N Hydrolase Hydrolase_3 HAD
Other DBs
NCBI-GeneID: 100459692
NCBI-ProteinID: XP_024112208
Ensembl: ENSPPYG00000004946
Position
12:108910737..108980666
AA seq 1042 aa
MENAHTKTVEEVLGHFGVNESTGLSLEQVKKLKERWGSNELPAEEGKTLLELVIEQFEDL
LVRILLLAACISFVLAWFEEGEETITAFVEPFVILLILVANAIVGVWQERNAENAIEALK
EYEPEMGKVYRQDRKSVQRIKAKDIVPGDIVEIAVGDKVPADIRLTSIKSTTLRVDQSIL
TGESVSVIKHTDPVPDPRAVNQDKKNMLFSGTNIAAGKAMGVVVATGVNTEIGKIRDEMV
ATEQERTPLQQKLDEFGEQLSKVISLICIAVWIINIGHFNDPVHGGSWIRGAIYYFKIAV
ALAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQ
MSVCRMFILDRVEGDTCSLNEFTITGSTYAPIGEVHKDDKPVKCHQYDGLVELATICALC
NDSALDYNEAKGVYEKVGEATETALTCLVEKMNVFDTELKGLSKIERANACNSVIKQLMK
KEFTLEFSRDRKSMSVYCTPNKPSRTSMSKMFVKGAPEGVIDRCTHIRVGSTKVPMTSGV
KQKIMSVIREWGSGSDTLRCLALATHDNPLRREEMHLEDSANFIKYETNLTFVGCVGMLD
PPRIEVASSVKLCRQAGIRVIMITGDNKGTAVAICRRIGIFRQDEDVTSKAFTGREFDEL
NPSAQRDACLNARCFARVEPSHKSKIVEFLQSFDEITAMTGDGVNDAPALKKAEIGIAMG
SGTAVAKTASEMVLADDNFSTIVAAVEEGRAIYNNMKQFIRYLISSNVGEVVCIFLTAAL
GFPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMNKPPRNPKEPLISGWLFFRYLAIG
CYVGAATVGAAAWWFIAADGGPRVSFYQLSHFLQCKEDNPDFEGVDCAIFESPYPMTMAL
SVLVTIEMCNALNSLSENQSLLRMPPWENIWLVGSICLSMSLHFLILYVEPLPLIFQITP
LNVTQWLMVLKISLPVILMDETLKFVARNYLEPGKECVQPATKSCSFSACTDGISWPFVL
LIMPLVIWVYSTDTNFSDMFWS
NT seq 3129 nt   +upstreamnt  +downstreamnt
atggagaacgcgcacacaaagacggtggaggaggtgctgggccacttcggcgtcaacgag
agtacggggctgagcctggagcaggtcaagaagcttaaggagagatggggctccaacgag
ttaccggctgaagaaggaaaaaccttgctggaacttgtgattgagcagtttgaagacttg
ctagttaggattttattactggcagcatgtatatcttttgttttggcttggtttgaagaa
ggtgaagaaacaattacagcctttgtagaaccttttgtaattttactcatattagtagcc
aatgcaattgtgggtgtgtggcaggaaagaaatgctgaaaatgccatcgaagcccttaag
gaatatgagcctgaaatgggcaaagtgtatcgacaggacagaaagagtgtacagcggatt
aaagctaaagacatagttcctggtgatattgtagaaattgctgttggtgacaaagttcct
gctgatataaggttaacttccatcaaatctaccacactaagagttgaccagtcaattctc
acaggtgaatctgtctctgtcatcaagcacactgatcccgtccctgacccacgagctgtc
aaccaagataaaaagaacatgctgttttctggtacaaacattgctgctgggaaagctatg
ggagtggtggtagcaactggagttaacactgaaattggcaagatccgggatgaaatggtg
gcaacagagcaggagagaacaccccttcagcaaaaactagatgaatttggggaacagctt
tccaaagtcatctcccttatttgcattgcagtctggatcataaatattgggcacttcaat
gacccggttcatggagggtcctggatcagaggtgctatttactactttaaaattgcagtg
gccctggctgtagcagccattcctgaaggtctgcctgcagtcatcaccacctgcctggct
cttggaactcgcagaatggcaaagaaaaatgccattgttcgaagcctcccgtctgtggaa
acccttggttgtacttctgttatctgctcggacaagactggtacacttacaacaaaccag
atgtcagtctgcaggatgttcattctggacagagtggaaggtgatacttgttcccttaat
gagtttaccataactgggtcaacttatgcacctattggagaagtgcataaagatgataaa
ccagtgaaatgtcaccagtatgatggtctggtagaattagcaacaatttgtgctctttgt
aatgactctgctttggattacaatgaggcaaagggtgtgtatgaaaaagttggagaagct
acagagactgctctcacttgcctagtagagaagatgaatgtatttgatactgaattgaag
ggtctttctaaaatagaacgtgcaaatgcctgcaactcagtcattaaacagctgatgaaa
aaggaattcactctagagttttcacgtgacagaaagtcaatgtcggtttactgtacacca
aataaaccaagcaggacatcaatgagcaagatgtttgtaaagggtgctcctgaaggtgtc
attgacaggtgcacccacattcgagttggaagtactaaggttcctatgacctctggagtc
aaacagaagatcatgtctgtcattcgagagtggggtagtggtagcgacacactgcgatgc
ctggccctggccactcatgacaacccactgagaagagaagaaatgcaccttgaggactct
gccaactttattaaatatgagaccaatctgaccttcgttggctgcgtgggcatgctggat
cctccgagaatcgaggtggcctcctccgtgaagctgtgtcggcaagcaggcatccgggtc
atcatgatcactggggacaacaagggcactgctgtggccatctgtcgccgcatcggcatc
ttcaggcaggatgaggacgtgacgtcaaaagctttcacaggccgggaatttgatgaactc
aacccctccgcccagcgagacgcctgcctgaatgcccgctgttttgctcgagttgaaccc
tcccacaagtctaaaatcgtagaatttcttcagtcttttgatgagattacagctatgact
ggcgatggcgtgaacgatgctcctgctctgaagaaagccgagattggcattgctatgggc
tctggcactgcagtggctaaaaccgcctctgagatggtcttggcagatgacaacttctcc
accatcgtggctgccgttgaggaggggcgggcaatctacaacaacatgaaacagttcatc
cgctacctcatctcgtccaacgtcggggaagttgtctgtattttcctgacagcagccctt
ggatttcccgaggctttgattcctgttcagctgctctgggtcaatctggtgacagatggc
ctgcctgccactgcactggggttcaaccctcctgatctggacatcatgaataaacctccc
cggaacccaaaggaaccattgatcagcgggtggctgtttttccgttacttggctattggc
tgttacgttggcgctgctaccgtgggtgctgctgcatggtggttcattgctgctgacggt
ggtccaagagtgtccttctaccagctgagtcatttcctacagtgtaaagaggacaacccg
gacttcgaaggcgtggattgtgcaatctttgaatccccatacccaatgacaatggcgctg
tctgttctagtaactatagaaatgtgtaacgccctcaacagcttgtccgaaaaccagtcc
ttgctgaggatgcccccctgggagaacatctggctcgtgggctccatctgcctgtccatg
tcactccacttcctgatcctctatgtcgaacccttgccactcatcttccagatcacaccg
ctgaacgtgacccagtggctgatggtgctgaaaatctccttgcccgtgattctcatggac
gagacgctcaagtttgtggcccgcaactacctggaacctggtaaagagtgtgtgcagcct
gccaccaaatcctgctcgttctcggcatgcaccgatgggatttcctggccgtttgtgctg
ctcataatgcccctggtgatctgggtctatagcacagacactaactttagcgatatgttc
tggtcttga

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (16)   
   KEGG PATHWAY (16)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (5)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
Protein sequence (1)   
   RefSeq(pep) (1)   
DNA sequence (1)   
   RefSeq(nuc) (1)   
Protein domain (7)   
   Pfam (7)   
All databases (34)   

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