KEGG   Pongo abelii (Sumatran orangutan): 100460111
Entry
100460111         CDS       T01416                                 
Symbol
HSD11B1L
Name
(RefSeq) hydroxysteroid 11-beta-dehydrogenase 1-like protein isoform X1
  KO
K15680  corticosteroid 11-beta-dehydrogenase isozyme 1 [EC:1.1.1.146]
Organism
pon  Pongo abelii (Sumatran orangutan)
Pathway
pon00140  Steroid hormone biosynthesis
pon00980  Metabolism of xenobiotics by cytochrome P450
pon01100  Metabolic pathways
pon05204  Chemical carcinogenesis - DNA adducts
Module
pon_M00109  C21-Steroid hormone biosynthesis, progesterone => cortisol/cortisone
Brite
KEGG Orthology (KO) [BR:pon00001]
 09100 Metabolism
  09103 Lipid metabolism
   00140 Steroid hormone biosynthesis
    100460111 (HSD11B1L)
  09111 Xenobiotics biodegradation and metabolism
   00980 Metabolism of xenobiotics by cytochrome P450
    100460111 (HSD11B1L)
 09160 Human Diseases
  09161 Cancer: overview
   05204 Chemical carcinogenesis - DNA adducts
    100460111 (HSD11B1L)
Enzymes [BR:pon01000]
 1. Oxidoreductases
  1.1  Acting on the CH-OH group of donors
   1.1.1  With NAD+ or NADP+ as acceptor
    1.1.1.146  11beta-hydroxysteroid dehydrogenase
     100460111 (HSD11B1L)
SSDB
Motif
Pfam: adh_short adh_short_C2 KR DUF1776
Other DBs
NCBI-GeneID: 100460111
NCBI-ProteinID: XP_002828544
Ensembl: ENSPPYG00000009430
UniProt: A0A6D2WCB5
Position
19:5591254..5599002
AA seq 287 aa
MKVLLLTGLGALFFAYYWDDNFDPASLQGARVLLTGANAGVGEELAYHYARLGSHLVLTA
HTEALLQKVVGNCRKLGAPKVFYIAADMASPEAPESVVQFALDKLGGLDYLVLNHIGGAP
AGTRARSPQATRWLMQVNFLSYVQLTSRALPSLTDSKGSLVVVSSLLGRVPTSFSTPYSA
AKFALDGFFGSLRRELDVQDVNVAITMCVLGLRDRASAAEAVRGVTRVKAAPGPKAALAV
IRGGATRAAGVFYPWRFHLLCLLRRWLPRPRAWFIRQELNVTAAAAA
NT seq 864 nt   +upstreamnt  +downstreamnt
atgaaggtgcttctcctcacagggctgggggccctgttctttgcctattattgggatgac
aacttcgacccagccagcctccagggagcgcgagtgctgctgacaggggccaacgctggt
gttggtgaggagctggcctatcactacgcgcgtctgggctcccacctggtgctcactgcc
cacactgaggctctcctgcagaaggtggtagggaactgccggaagctgggcgcccccaag
gtcttctacatcgcggcggacatggcctcccctgaggcgcccgagagcgtggtgcagttt
gcgctggacaagctgggcgggctggactacctcgtgctgaaccacatcggcggcgccccg
gccggcacgcgagcccgcagcccccaggcaacgcgctggctcatgcaggtaaactttctg
agctacgtgcaactgacgtcgcgggcgctgcccagcctgacggacagcaaaggctccctg
gtggtggtgtcctcgctgctcggccgcgtgcccacgtcgttctccactccctactcggcg
gccaagtttgcgctggacggcttcttcggctccctgcggcgggagctggacgtgcaggac
gtgaacgtggccatcaccatgtgcgtcctgggcctccgagatcgcgcctccgccgccgag
gcagtcaggggagtcacgagggtcaaggcggccccggggcccaaggcagccctggccgta
atccgcggcggcgccacgcgcgcggccggcgtcttctacccgtggcgtttccacctgctg
tgcttgctccggcgctggctgccgcgcccgcgggcctggtttatccgccaggagctcaac
gtcacggccgcggctgcagcctga

  All links  
Ontology (2)   
   KEGG BRITE (2)   
Pathway (5)   
   KEGG PATHWAY (4)   
   KEGG MODULE (1)   
Chemical substance (13)   
   KEGG COMPOUND (13)   
Chemical reaction (6)   
   KEGG ENZYME (1)   
   KEGG REACTION (5)   
Genome (1)   
   KEGG GENOME (1)   
Gene (5)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
Protein sequence (12)   
   UniProt (1)   
   RefSeq(pep) (11)   
DNA sequence (13)   
   RefSeq(nuc) (13)   
Protein domain (4)   
   Pfam (4)   
All databases (61)   

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