KEGG   Panthera pardus (leopard): 109255094
Entry
109255094         CDS       T06062                                 
Symbol
HSD11B1
Name
(RefSeq) corticosteroid 11-beta-dehydrogenase isozyme 1 isoform X1
  KO
K15680  corticosteroid 11-beta-dehydrogenase isozyme 1 [EC:1.1.1.146]
Organism
ppad  Panthera pardus (leopard)
Pathway
ppad00140  Steroid hormone biosynthesis
ppad00980  Metabolism of xenobiotics by cytochrome P450
ppad01100  Metabolic pathways
ppad05204  Chemical carcinogenesis - DNA adducts
Module
ppad_M00109  C21-Steroid hormone biosynthesis, progesterone => cortisol/cortisone
Brite
KEGG Orthology (KO) [BR:ppad00001]
 09100 Metabolism
  09103 Lipid metabolism
   00140 Steroid hormone biosynthesis
    109255094 (HSD11B1)
  09111 Xenobiotics biodegradation and metabolism
   00980 Metabolism of xenobiotics by cytochrome P450
    109255094 (HSD11B1)
 09160 Human Diseases
  09161 Cancer: overview
   05204 Chemical carcinogenesis - DNA adducts
    109255094 (HSD11B1)
Enzymes [BR:ppad01000]
 1. Oxidoreductases
  1.1  Acting on the CH-OH group of donors
   1.1.1  With NAD+ or NADP+ as acceptor
    1.1.1.146  11beta-hydroxysteroid dehydrogenase
     109255094 (HSD11B1)
SSDB
Motif
Pfam: adh_short adh_short_C2 KR THF_DHG_CYH_C Shikimate_DH DUF1776 NAD_binding_2 2-Hacid_dh_C Helicase_RecD ADH_zinc_N
Other DBs
NCBI-GeneID: 109255094
NCBI-ProteinID: XP_019285057
Ensembl: ENSPPRG00000010503
UniProt: A0A9V1EN65
Position
Unknown
AA seq 292 aa
MAFMKKYLPPILGIFLAYYYYSANEEFRPEMLQGKKVIVTGASKGIGEQMAYHLAKMGAH
VVVTARSKENLKKIVSHCLELGAASAHYIAGTMENMTFAEQFVAKAGKLMGGLDMLILNH
ITNTSMNLFSGDIHLVRRSMEVNFLSYVVLSATALPMLKQSNGSIVVVSSKAGKMASPLI
APYSASKFALDGFFSSIRMEHSVAKINVSITLCILGLINTDTAMKAISGIVNMEASPKEE
CALEIIKGGALRQEEVYYDNSVWTALLLGNPGRKILELFSLRSYSLDKFIIN
NT seq 879 nt   +upstreamnt  +downstreamnt
atggcttttatgaaaaaatatctcccccccattctggggatcttcttggcctactactac
tattctgcgaatgaggaattcagaccagagatgctccaaggaaagaaagtgattgtcaca
ggggccagcaaggggattggagaacagatggcctatcatctggcaaagatgggagcccat
gtggtggtgacagcaaggtctaaagaaaatctaaagaagatagtatcccattgcctggag
cttggagcagcctcagcacactacattgctggcaccatggagaatatgacctttgcagag
caatttgttgccaaagctggaaagctcatggggggactagacatgcttattctcaaccac
atcaccaacacttctatgaatctgtttagtggtgatatccacctcgtgcgcagaagcatg
gaagtcaacttcctcagttatgtggtcctgagtgctactgccttgcctatgctgaagcag
agcaatggaagcattgttgtcgtgtcctcgaaggctgggaaaatggctagtccacttatt
gcgccctattctgcaagcaagtttgccctggatgggtttttctcctccatcaggatggaa
cattcagtggccaagattaatgtatcgatcactctctgtatcctcggcctcataaacaca
gacacagccatgaaggccatttctggaatagtcaacatggaggcatctccaaaggaagaa
tgtgccctggagatcatcaaagggggagctctgcgccaagaggaagtgtactatgacaac
tcagtctggacagctctcctgctgggaaatccagggaggaagattctggaactcttctcc
ttaagaagttatagtttggacaagtttataatcaactaa

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (5)   
   KEGG PATHWAY (4)   
   KEGG MODULE (1)   
Chemical substance (13)   
   KEGG COMPOUND (13)   
Chemical reaction (6)   
   KEGG ENZYME (1)   
   KEGG REACTION (5)   
Genome (1)   
   KEGG GENOME (1)   
Gene (4)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
Protein sequence (12)   
   UniProt (1)   
   RefSeq(pep) (11)   
DNA sequence (11)   
   RefSeq(nuc) (11)   
Protein domain (10)   
   Pfam (10)   
All databases (64)   

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