KEGG   Panthera pardus (leopard): 109275948
Entry
109275948         CDS       T06062                                 
Symbol
PDGFRB
Name
(RefSeq) platelet-derived growth factor receptor beta
  KO
K05089  platelet-derived growth factor receptor beta [EC:2.7.10.1]
Organism
ppad  Panthera pardus (leopard)
Pathway
ppad01521  EGFR tyrosine kinase inhibitor resistance
ppad04010  MAPK signaling pathway
ppad04014  Ras signaling pathway
ppad04015  Rap1 signaling pathway
ppad04020  Calcium signaling pathway
ppad04072  Phospholipase D signaling pathway
ppad04151  PI3K-Akt signaling pathway
ppad04510  Focal adhesion
ppad04540  Gap junction
ppad04630  JAK-STAT signaling pathway
ppad04810  Regulation of actin cytoskeleton
ppad05165  Human papillomavirus infection
ppad05200  Pathways in cancer
ppad05206  MicroRNAs in cancer
ppad05214  Glioma
ppad05215  Prostate cancer
ppad05218  Melanoma
ppad05230  Central carbon metabolism in cancer
ppad05231  Choline metabolism in cancer
Brite
KEGG Orthology (KO) [BR:ppad00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    109275948 (PDGFRB)
   04014 Ras signaling pathway
    109275948 (PDGFRB)
   04015 Rap1 signaling pathway
    109275948 (PDGFRB)
   04630 JAK-STAT signaling pathway
    109275948 (PDGFRB)
   04020 Calcium signaling pathway
    109275948 (PDGFRB)
   04072 Phospholipase D signaling pathway
    109275948 (PDGFRB)
   04151 PI3K-Akt signaling pathway
    109275948 (PDGFRB)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    109275948 (PDGFRB)
   04540 Gap junction
    109275948 (PDGFRB)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    109275948 (PDGFRB)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    109275948 (PDGFRB)
   05206 MicroRNAs in cancer
    109275948 (PDGFRB)
   05230 Central carbon metabolism in cancer
    109275948 (PDGFRB)
   05231 Choline metabolism in cancer
    109275948 (PDGFRB)
  09162 Cancer: specific types
   05214 Glioma
    109275948 (PDGFRB)
   05218 Melanoma
    109275948 (PDGFRB)
   05215 Prostate cancer
    109275948 (PDGFRB)
  09172 Infectious disease: viral
   05165 Human papillomavirus infection
    109275948 (PDGFRB)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    109275948 (PDGFRB)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:ppad01001]
    109275948 (PDGFRB)
  09183 Protein families: signaling and cellular processes
   04090 CD molecules [BR:ppad04090]
    109275948 (PDGFRB)
Enzymes [BR:ppad01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.10  Protein-tyrosine kinases
    2.7.10.1  receptor protein-tyrosine kinase
     109275948 (PDGFRB)
Protein kinases [BR:ppad01001]
 Receptor tyrosine kinases (RTK)
  PDGFR family [OT]
   109275948 (PDGFRB)
CD molecules [BR:ppad04090]
 Proteins
  109275948 (PDGFRB)
SSDB
Motif
Pfam: PK_Tyr_Ser-Thr Pkinase ig Ig_3 I-set Ig_2 V-set VEGFR-1-like_Ig-like Haspin_kinase
Other DBs
NCBI-GeneID: 109275948
NCBI-ProteinID: XP_019319951
Ensembl: ENSPPRG00000014021
UniProt: A0A9W2VW89
Position
Unknown
AA seq 1096 aa
MPAPVLKGQVLLLPLLLLLGPQASWGLVITPPEPELVLNISSTFVLTCSGAAPVVWERMS
QKPLQKTAKNQDGTFSSTLTLTNVTGLDTGEYFCTYKNSLGPEPAERKRLYIFVPDPTMG
FLPVFPEDLFIFLTEISEITIPCRVTDPSLVVTLHEKKVDIPLPIPYDHQRGFSGIFEDK
TYVCKTIIGDREVDSEAYYVYSLQVSSINVSVNAVQTVVRQGENITIMCIVTGNEVVNFE
WTYPRMESGRLVEPVTDFLFNVPSHIRSILHIPNAELGDSGTYICNVSESVNDHRDEKSI
NVTVVESGYVQLLGELDAVQFAELHRSRTLQVVFEAYPPPTVMWLKDNRTLGDSSAGEIA
LSTRNVSETRYVSELTLVRVKVAEAGYYTMRAFHEDAEAQISFQLQVNVPVRVLELSENH
PASGEQTVRCRGRGMPQPHLTWSTCSDLKRCPRELPPTPLGNSSEEDSQLETNVTYWPED
QEFEVVSTLRLRRVDQPLSVRCTLHNLLGHDMQEVTVVPHSLPFKVVVISAILALVVLTI
ISLIILIMLWQKKPRYEIRWKVIESVSSDGHEYIYVDPMQLPYDSTWELPRDQLVLGRTL
GSGAFGQVVEATAHGLSHSQATMKVAVKMLKSTARSSEKQALMSELKIMSHLGPHLNVVN
LLGACTKGGPIYIITEYCRYGDLVDYLHRNKHTFLQRCSDKRRPPSAELYSNALPAGLPL
PSHVSLPGESDGGYMDMSKDESVDYVPMLDMKGGIKYADIESSSYVAPYDNYVPTAPERT
CRATLINESPVLSYTDLVGFSYQVANGMEFLASKNCVHRDLAARNVLICEGKLVKICDFG
LARDIMRDSNYISKGSTFLPLKWMAPESIFNSLYTTLSDVWSFGILLWEIFTLGGTPYPE
LPMNEQFYNAIKRGYRMAQPAHASDEIYEIMQKCWEEKFEIRPPFSQLVLLLERLLGEGY
KKKYQQVDEEFLRSDHPAVLRSQARFPGFNGLRSPLDTSSVLYTAVQPNESDNDYIIPLP
DPKPEIADEGPLEGSPSLASSTLNEVNTSSTISCDSPLEPQEEPEPEPQLEPQVEPEPPL
DSCCPGPRAEAEDSFL
NT seq 3291 nt   +upstreamnt  +downstreamnt
atgccagctcctgtcctcaaaggccaggtgctgttgctgcccctgctgttgctgctggga
ccacaggcctcctggggcctggtcatcacacctccggagccagagcttgtcctcaatatc
tccagcaccttcgttctgacctgttcgggtgcagctccggtggtgtgggaacggatgtcc
cagaagcccctgcagaaaacggccaagaaccaggatggcaccttctccagcacactgaca
ctgaccaatgtcactgggctagacacgggagaatacttttgcacctacaaaaactccctc
gggccggagcctgctgagcgaaaacggctctacatctttgtgccagatccgactatgggc
tttcttccggtcttccccgaggacctgttcatctttctcacggaaatatctgagatcaca
attccctgccgagtgacggatccgagcctggtggtgacactgcacgagaagaaagtggat
attccactgcccatcccctatgaccaccaacgtggcttctctggtatcttcgaggacaag
acctatgtctgcaaaaccatcatcggggacagggaagtggattctgaagcctactatgtc
tacagtctccaggtgtcgtccatcaatgtctcagtgaatgcagtgcagactgtggtccgc
cagggtgagaacatcaccatcatgtgcattgtgaccggaaatgaggtggtcaactttgaa
tggacatacccacgcatggagagtgggcggctggtggagccagtgactgacttcctcttc
aatgtaccctcccacatacgctccatcctgcacatccctaatgccgagcttggcgattca
gggacctacatctgcaatgtatcggagagtgtgaatgaccatcgagatgaaaagtccatc
aatgtcactgtggttgagagtggctacgtgcagctgctgggagagctggacgccgtacaa
ttcgcggagctgcaccgcagccggactctgcaggtggtgttcgaggcctacccgccgcct
actgtcatgtggctcaaggacaaccgcacgctaggcgactccagcgcaggcgagattgcc
ctgtccacacgcaatgtgtctgagacccggtatgtgtcagaactgacattggtgcgggtg
aaggtggctgaggctggctactacaccatgcgggccttccacgaggatgcagaggcccag
atctccttccagctgcaggtcaatgtgcctgtccgtgtgctggagctgagtgaaaaccat
cctgccagcggggagcagacagtccgctgtcgcggccggggcatgccccagccacacctc
acctggtctacctgcagtgacctcaaaagatgtccgcgcgagctgccgcccaccccactg
gggaacagttccgaggaggacagccagctggagactaacgtgacttactggcctgaggat
caggagttcgaggtggtgagcacgctgcgcctgcgccgtgtggatcagcctctgtccgtg
cgctgcactctgcacaacctgctgggccacgacatgcaggaggtcaccgtggtgccacat
tctctgcccttcaaggtggtggtgatctcggccatcctggccttggtggtcctcacaatc
atctccctcatcatcctcatcatgctctggcaaaagaagccacgttatgagatccgatgg
aaggtgattgaatctgtgagctctgatggccatgagtacatctacgtggaccctatgcag
ctgccctatgactctacctgggagctgccacgggaccagcttgtgcttggacgcaccctc
ggctctggggcctttgggcaggtggtggaggccacagctcacggcctgagccattctcag
gccacgatgaaagtggcggtcaagatgctgaaatccacagcccgcagcagcgagaagcag
gccctcatgtcagagctgaagatcatgagtcaccttgggccccatctgaacgtggtcaac
ttgctgggggcctgcaccaaaggaggacccatctacatcatcacggagtactgccgctac
ggcgacctggtggactaccttcaccgcaacaagcacaccttcctgcagcgctgctccgac
aagcgccgcccgcccagcgccgagctctacagcaacgccctgcccgcggggctccctctg
cccagccacgtgtccctgcctggggagagtgacggtggctacatggacatgagcaaggac
gagtcggtggactacgtgcccatgctggacatgaaaggaggaatcaaatatgcagacatc
gagtcctccagctacgtggccccttatgacaactacgtccccacagctcctgagaggacc
tgtcgggcaactctgatcaacgagtccccggtgcttagctacacagatcttgtgggcttc
agctaccaggtggccaatggcatggagttcctggcctccaagaactgcgtccaccgagat
ctggcagccaggaacgtgctcatctgtgaaggcaagctggtcaagatctgtgactttggc
ctggctcgtgacatcatgagggactcgaactatatctccaaaggcagtaccttcctgcct
ctgaagtggatggctcccgagagcatcttcaacagcctctataccaccctgagtgatgtg
tggtccttcgggatcctactctgggagatcttcaccctgggtggcaccccttacccagag
ctgcccatgaacgagcagttctataatgccatcaagcggggttaccgaatggcccagcct
gcccatgcctccgatgaaatctacgagatcatgcagaagtgctgggaagagaagtttgag
atccggcctcccttctcccagctggtgctgcttctcgagaggctgctgggtgaggggtac
aagaagaagtaccagcaggtggatgaggagtttctgaggagcgaccacccagccgtcctt
cggtcccaagcccgctttcccggcttcaatggactccgatcccccctggacaccagctct
gtgctctacactgctgtgcagcccaacgagagtgacaatgactatatcatccccctgcct
gaccccaaacccgagattgctgatgagggccccctggagggttcccccagccttgccagc
tccaccctgaatgaagtcaacacctcctctaccatctcctgtgacagccccctggaaccc
caagaggagccagagccagagccccagctcgagccccaggtggagccagagccaccactg
gattcatgttgccctgggcctcgggccgaggcggaggatagcttcctgtag

  All links  
Ontology (4)   
   KEGG BRITE (4)   
Pathway (19)   
   KEGG PATHWAY (19)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (4)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
Protein sequence (4)   
   UniProt (1)   
   RefSeq(pep) (3)   
DNA sequence (3)   
   RefSeq(nuc) (3)   
Protein domain (9)   
   Pfam (9)   
All databases (45)   

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