KEGG   Panthera pardus (leopard): 6262379
Entry
6262379           CDS       T06062                                 
Symbol
ND1
Name
(RefSeq) NADH dehydrogenase subunit 1
  KO
K03878  NADH-ubiquinone oxidoreductase chain 1 [EC:7.1.1.2]
Organism
ppad  Panthera pardus (leopard)
Pathway
ppad00190  Oxidative phosphorylation
ppad01100  Metabolic pathways
ppad04714  Thermogenesis
ppad04723  Retrograde endocannabinoid signaling
ppad05010  Alzheimer disease
ppad05012  Parkinson disease
ppad05014  Amyotrophic lateral sclerosis
ppad05016  Huntington disease
ppad05020  Prion disease
ppad05022  Pathways of neurodegeneration - multiple diseases
ppad05208  Chemical carcinogenesis - reactive oxygen species
ppad05415  Diabetic cardiomyopathy
Module
ppad_M00142  NADH:ubiquinone oxidoreductase, mitochondria
Brite
KEGG Orthology (KO) [BR:ppad00001]
 09100 Metabolism
  09102 Energy metabolism
   00190 Oxidative phosphorylation
    6262379 (ND1)
 09150 Organismal Systems
  09156 Nervous system
   04723 Retrograde endocannabinoid signaling
    6262379 (ND1)
  09159 Environmental adaptation
   04714 Thermogenesis
    6262379 (ND1)
 09160 Human Diseases
  09161 Cancer: overview
   05208 Chemical carcinogenesis - reactive oxygen species
    6262379 (ND1)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    6262379 (ND1)
   05012 Parkinson disease
    6262379 (ND1)
   05014 Amyotrophic lateral sclerosis
    6262379 (ND1)
   05016 Huntington disease
    6262379 (ND1)
   05020 Prion disease
    6262379 (ND1)
   05022 Pathways of neurodegeneration - multiple diseases
    6262379 (ND1)
  09166 Cardiovascular disease
   05415 Diabetic cardiomyopathy
    6262379 (ND1)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03029 Mitochondrial biogenesis [BR:ppad03029]
    6262379 (ND1)
Enzymes [BR:ppad01000]
 7. Translocases
  7.1  Catalysing the translocation of protons
   7.1.1  Linked to oxidoreductase reactions
    7.1.1.2  NADH:ubiquinone reductase (H+-translocating)
     6262379 (ND1)
Mitochondrial biogenesis [BR:ppad03029]
 Mitochondrial DNA transcription, translation, and replication factors
  Mitochondrial DNA-encoded proteins
   Mitochondrial respiratory chain complex I
    6262379 (ND1)
SSDB
Motif
Pfam: NADHdh
Other DBs
NCBI-GeneID: 6262379
NCBI-ProteinID: YP_001874840
UniProt: B2WVM3
AA seq 318 aa
MFMINILSLIVPILLAVAFLTLVERKVLGYMQLRKGPNVVGPYGLLQPIADAMKLFTKEP
LRPLTSSMFMFIMAPILALTLALTMWIPLPMPYPLINMNLGVLFMLAMSSLAVYSILWSG
WASNSKYALIGALRAVAQTISYEVTLAIILLSVLLMNGSFTLATLITTQEYIWLIIPAWP
LAMMWFISTLAETNRAPFDLTEGESELVSGFNVEYAAGPFALFFLAEYANIIMMNILTTI
LFFGAFHSPYMPELYTTNFTVKTLILTTTFLWIRASYPRFRYDQLMHLLWKSFLPLTLAL
CMWHVSLPIITASIPPQT
NT seq 956 nt   +upstreamnt  +downstreamnt
atgttcataattaatatcctctcactaatcgtcccaattctcctcgccgtggccttccta
actctagttgaacgtaaagtactaggctacatgcaacttcgtaaagggcctaatgtcgta
gggccatatggcctacttcaacccattgcagacgccataaaactcttcactaaagaacct
ctccgacccctcacatcctccatattcatatttattatagcacccatcctagccctcaca
ctagccctaaccatatgaatcccactacccataccatacccgctcattaacataaaccta
ggggtgctattcatactagccatatccagcctagctgtttactccatcctatgatccgga
tgggcttcaaactcaaaatatgctctaatcggcgccctacgggccgtagctcaaacaatc
tcatatgaagtcacactagctattatcctcttatcagtactactaataaatggatcattc
acattagccacactaattaccactcaagaatacatctgacttattattcccgcatgaccc
ctagctataatatgattcatctctacactagcagaaaccaaccgagccccatttgacctc
acagaaggagaatcggagcttgtttccggattcaacgtagaatacgcagcaggtcccttt
gccctattctttctagcagaatatgccaacattatcataataaacatcctcacaacaatc
ctgttcttcggagcatttcacagcccctatataccagagctatacaccaccaacttcact
gtaaaaactctaatcctaacaaccaccttcctatgaatccgagcatcttatccacggttc
cgatacgaccaattaatacacctcctatgaaaaagctttctaccccttacccttgcccta
tgcatatgacatgtctccctacccatcattacagcaagcatcccaccccaaacata

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