KEGG   Pan paniscus (bonobo): 100968191
Entry
100968191         CDS       T02283                                 
Symbol
IRAK4
Name
(RefSeq) interleukin-1 receptor-associated kinase 4 isoform X1
  KO
K04733  interleukin-1 receptor-associated kinase 4 [EC:2.7.11.1]
Organism
pps  Pan paniscus (bonobo)
Pathway
pps04010  MAPK signaling pathway
pps04064  NF-kappa B signaling pathway
pps04620  Toll-like receptor signaling pathway
pps04621  NOD-like receptor signaling pathway
pps04722  Neurotrophin signaling pathway
pps04936  Alcoholic liver disease
pps05132  Salmonella infection
pps05133  Pertussis
pps05135  Yersinia infection
pps05140  Leishmaniasis
pps05142  Chagas disease
pps05145  Toxoplasmosis
pps05152  Tuberculosis
pps05161  Hepatitis B
pps05162  Measles
pps05164  Influenza A
pps05168  Herpes simplex virus 1 infection
pps05169  Epstein-Barr virus infection
pps05170  Human immunodeficiency virus 1 infection
pps05171  Coronavirus disease - COVID-19
pps05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:pps00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    100968191 (IRAK4)
   04064 NF-kappa B signaling pathway
    100968191 (IRAK4)
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    100968191 (IRAK4)
   04621 NOD-like receptor signaling pathway
    100968191 (IRAK4)
  09156 Nervous system
   04722 Neurotrophin signaling pathway
    100968191 (IRAK4)
 09160 Human Diseases
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    100968191 (IRAK4)
   05161 Hepatitis B
    100968191 (IRAK4)
   05171 Coronavirus disease - COVID-19
    100968191 (IRAK4)
   05164 Influenza A
    100968191 (IRAK4)
   05162 Measles
    100968191 (IRAK4)
   05168 Herpes simplex virus 1 infection
    100968191 (IRAK4)
   05169 Epstein-Barr virus infection
    100968191 (IRAK4)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    100968191 (IRAK4)
   05135 Yersinia infection
    100968191 (IRAK4)
   05133 Pertussis
    100968191 (IRAK4)
   05152 Tuberculosis
    100968191 (IRAK4)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    100968191 (IRAK4)
   05140 Leishmaniasis
    100968191 (IRAK4)
   05142 Chagas disease
    100968191 (IRAK4)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    100968191 (IRAK4)
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    100968191 (IRAK4)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:pps01001]
    100968191 (IRAK4)
Enzymes [BR:pps01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.1  non-specific serine/threonine protein kinase
     100968191 (IRAK4)
Protein kinases [BR:pps01001]
 Serine/threonine kinases: TKL group
  IRAK family
   100968191 (IRAK4)
SSDB
Motif
Pfam: PK_Tyr_Ser-Thr Pkinase Pkinase_fungal Haspin_kinase Death RecA_C
Other DBs
NCBI-GeneID: 100968191
NCBI-ProteinID: XP_003825790
Ensembl: ENSPPAG00000027862
UniProt: A0A2R8ZXJ4
Position
10:complement(50383896..50414571)
AA seq 460 aa
MNKPITPSTYVRCLNVGLIRKLSDFIDPQEGWKKLAVAIKKPSGDDRYNQFHIRRFEALL
QTGKSPTSELLFDWGTTNCTVGDLVDLLIQNEFFAPASLLLPDAVPKTANTLPSKEAVTV
QQKQMPFYDKDRTLMTPVQNLEQSYMPPDSSSPENKSLEVSDTRFHSFSFYELKNVTNNF
DERPISVGGNKMGEGGFGVVYKGYVNNTTVAVKKLAAMVDITTEELKQQFDQEIKVMAKC
QHENLVELLGFSSDGDDLCLVYVYMPNGSLLDRLSCLDGTPPLSWHMRCKIAQGAANGIN
FLHENHHIHRDIKSANILLDQAFTAKISDFGLARASEKFAQTVMTSRIVGTTAYMAPEAL
RGEITPKSDIYSFGVVLLEIITGLPAVDEHREPQLLLDIKEEIEDEEKTIEDYIDKKMND
ADSTSVETMYSVASECLHEKKNKRPDIKKVQQLLQEMTAS
NT seq 1383 nt   +upstreamnt  +downstreamnt
atgaacaaacccataacaccatcaacatatgtgcgctgcctcaatgttggactaattagg
aagctgtcagattttattgatcctcaagaaggatggaagaagttagctgtagctattaaa
aaaccatctggtgatgatagatacaatcagtttcacataaggagatttgaagcattactt
caaactggaaaaagtcccacttctgaattactgtttgactggggcaccacaaattgcaca
gttggtgatcttgtggatcttttgatccaaaatgaattttttgctcctgcgagtcttttg
ctcccagatgctgttcccaaaactgctaatacactaccttctaaagaagctgtaacagtt
cagcaaaaacagatgcctttctatgacaaagacaggacattgatgacacctgtgcagaat
cttgaacaaagctatatgccacctgactcctcaagtccagaaaataaaagtttagaagtt
agtgatacacgttttcacagtttttcattttatgaattgaagaatgtcacaaataacttt
gatgaacgacccatttctgttggtggtaataaaatgggagagggaggatttggagttgta
tataaaggctacgtaaataacacaactgtggcagtgaagaagcttgcagcaatggttgac
attactactgaagaactgaaacagcagtttgatcaagaaataaaagtaatggcaaagtgt
caacatgaaaacttagtagaactacttggtttctcaagtgatggagatgacctctgctta
gtatatgtttacatgcctaatggttcattgctagacagactctcttgcttggatggtact
ccaccactttcttggcacatgagatgcaagattgctcagggtgcagctaatggcatcaat
tttctacatgaaaatcatcatattcatagagatattaaaagtgcaaatatcttactagat
caagcttttactgctaaaatatctgactttggccttgcacgggcttctgagaagtttgcc
cagacagtcatgactagcagaattgtgggaacaacagcttatatggcaccagaagctttg
cgtggagaaataacacccaaatctgatatttacagctttggtgtggttttactagaaata
ataactggacttccagctgtggatgaacaccgtgaacctcagttattgctagatattaaa
gaagaaattgaagatgaagaaaagacaattgaagattatattgataaaaagatgaatgat
gctgattccacttcagttgaaactatgtactctgttgctagtgaatgtctgcatgaaaag
aaaaataagagaccagacattaagaaggttcaacaactgctgcaagagatgacagcttct
taa

  All links  
Gene (4)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
Protein sequence (11)   
   UniProt (1)   
   RefSeq(pep) (10)   
DNA sequence (10)   
   RefSeq(nuc) (10)   
Protein domain (6)   
   Pfam (6)   
All databases (31)   

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KEGG   Pan paniscus (bonobo): 100981891
Entry
100981891         CDS       T02283                                 
Symbol
IRAK1
Name
(RefSeq) interleukin-1 receptor-associated kinase 1 isoform X2
  KO
K04730  interleukin-1 receptor-associated kinase 1 [EC:2.7.11.1]
Organism
pps  Pan paniscus (bonobo)
Pathway
pps04010  MAPK signaling pathway
pps04064  NF-kappa B signaling pathway
pps04620  Toll-like receptor signaling pathway
pps04722  Neurotrophin signaling pathway
pps04936  Alcoholic liver disease
pps05132  Salmonella infection
pps05133  Pertussis
pps05135  Yersinia infection
pps05140  Leishmaniasis
pps05142  Chagas disease
pps05145  Toxoplasmosis
pps05152  Tuberculosis
pps05161  Hepatitis B
pps05162  Measles
pps05168  Herpes simplex virus 1 infection
pps05169  Epstein-Barr virus infection
pps05170  Human immunodeficiency virus 1 infection
pps05171  Coronavirus disease - COVID-19
pps05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:pps00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    100981891 (IRAK1)
   04064 NF-kappa B signaling pathway
    100981891 (IRAK1)
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    100981891 (IRAK1)
  09156 Nervous system
   04722 Neurotrophin signaling pathway
    100981891 (IRAK1)
 09160 Human Diseases
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    100981891 (IRAK1)
   05161 Hepatitis B
    100981891 (IRAK1)
   05171 Coronavirus disease - COVID-19
    100981891 (IRAK1)
   05162 Measles
    100981891 (IRAK1)
   05168 Herpes simplex virus 1 infection
    100981891 (IRAK1)
   05169 Epstein-Barr virus infection
    100981891 (IRAK1)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    100981891 (IRAK1)
   05135 Yersinia infection
    100981891 (IRAK1)
   05133 Pertussis
    100981891 (IRAK1)
   05152 Tuberculosis
    100981891 (IRAK1)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    100981891 (IRAK1)
   05140 Leishmaniasis
    100981891 (IRAK1)
   05142 Chagas disease
    100981891 (IRAK1)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    100981891 (IRAK1)
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    100981891 (IRAK1)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:pps01001]
    100981891 (IRAK1)
Enzymes [BR:pps01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.1  non-specific serine/threonine protein kinase
     100981891 (IRAK1)
Protein kinases [BR:pps01001]
 Serine/threonine kinases: TKL group
  IRAK family
   100981891 (IRAK1)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr Death RAMP APH
Other DBs
NCBI-GeneID: 100981891
NCBI-ProteinID: XP_034805612
Ensembl: ENSPPAG00000040186
Position
X:complement(154050776..154060165)
AA seq 712 aa
MAGGPGPGEPAAPGAQHFLYEVPPWVMCRFYKVMDALEPADWCQFAALIVRDQTELRLCE
RSGQRTASVLWPWINRNARVADLVHILTHLQLLRARDIITAWHPPALLPSPSTTAPRPSS
IPAPAEAEAWSPRKLPSSASTLLSPAFPGSQTHSGPELGLVPSPASLWPPPPSPAPSSTK
PGPESSVSLLQGARPSPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKR
LKEDADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRL
HCQTQACPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFG
LARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAG
QRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLDP
RPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQVYERLEKLQAVVAGVPGHSEAASCIPP
SPQENSYVSSTGSAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALR
SWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQI
IINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS
NT seq 2139 nt   +upstreamnt  +downstreamnt
atggccggggggccgggcccgggggagcccgcagcccccggcgcccagcacttcttgtac
gaggtgccgccctgggtcatgtgccgcttctacaaagtgatggacgccctggagcccgcc
gactggtgccagttcgccgccctgatcgtgcgcgaccagaccgagctgcggctgtgcgag
cgctccgggcagcgcacggccagcgtcctgtggccctggatcaaccgcaacgcccgtgtg
gccgacctcgtgcacatcctcacgcacctgcagctgctccgtgcgcgggacatcatcaca
gcctggcaccctcccgccctgcttccgtccccaagcaccactgccccgaggcccagcagc
atccctgcacccgccgaggccgaggcctggagcccccggaagttgccatcctcagcctcc
accctcctctccccagcttttccaggctcccagacccattcagggcctgagctcggcctg
gtcccaagccctgcttccctgtggcctccaccgccatctccagccccttcctctaccaag
ccaggcccagagagctcagtgtccctcctgcagggagcccgcccctctccgttttgctgg
cccctctgtgagatttcccggggcacccacaacttctcagaggagctcaagatcggggag
ggtggctttgggtgcgtgtaccgggcggtgatgaggaacacggtgtatgctgtgaagagg
ctgaaggaggacgctgacctggagtggactgcagtgaagcagagcttcctgaccgaggtg
gagcagctgtccaggtttcgtcacccaaacattgtggactttgctggctactgtgctcag
aacggcttctactgcctggtgtacggcttcctgcccaacggctccctggaggaccgtctc
cactgccagacccaggcctgcccacctctctcctggcctcagcgactggacatccttctg
ggtacagcccgggcaattcagtttctacatcaggacagccccagcctcatccatggagac
atcaagagttccaacgtccttctggatgagaggctgacacccaagctgggagactttggc
ctggcccggttcagccgctttgccgggtccagccccagccagagcagcatggtggcccgg
acacagacagtgcggggcaccctggcctacctgcccgaggagtacatcaagacgggaagg
ctggctgtggacacggacaccttcagctttggggtggtagtgctagagaccttggctggt
cagagggctgtgaagacgcacggtgccaggaccaagtatctgaaagacctggtggaagag
gaggctgaggaggctggagtggctttgagaagcacccagagcacactgcaagcaggtctg
gctgcagatgcctgggctgctcccatcgccatgcagatctacaagaagcacctggacccc
aggcccgggccctgcccacctgagctgggcctgggcctgggccagctggcctgctgctgc
ctgcaccgccgggccaaaaggaggcctcctatgacccaggtgtacgagaggctagagaag
ctgcaggcagtggtggcgggggtgcccgggcattcggaggccgccagctgcatcccccct
tccccgcaggagaactcctacgtgtccagcactggcagtgcccacagtggggctgctcca
tggcagcccctggcagcgccatcaggagccagtgcccaggcagcagagcagctccagaga
ggccccaaccagcccgtggagagtgacgagagcctaggcggcctctctgctgccctgcgc
tcctggcacttgactccaagctgccctctggacccagcacccctcagggaggccggctgt
cctcagggggacacggcgggagaatcgagctgggggagtggcccaggatcccggcccaca
gccgtggaaggactggcccttggcagctctgcatcatcgtcgtcagagccaccgcagatt
atcatcaaccctgcccgacagaagatggtccagaagctggccctgtacgaggatggggcc
ctggacagcctgcagctgctgtcgtccagctccctcccaggcttgggcctggaacaggac
aggcaggggcccgaagaaagtgatgaatttcagagctga

  All links  
Gene (4)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
Protein sequence (4)   
   RefSeq(pep) (4)   
DNA sequence (4)   
   RefSeq(nuc) (4)   
Protein domain (5)   
   Pfam (5)   
All databases (17)   

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