KEGG   Pan paniscus (bonobo): 100970917
Entry
100970917         CDS       T02283                                 
Symbol
PRKACB
Name
(RefSeq) cAMP-dependent protein kinase catalytic subunit beta isoform X5
  KO
K04345  protein kinase A [EC:2.7.11.11]
Organism
pps  Pan paniscus (bonobo)
Pathway
pps01522  Endocrine resistance
pps04010  MAPK signaling pathway
pps04014  Ras signaling pathway
pps04020  Calcium signaling pathway
pps04024  cAMP signaling pathway
pps04062  Chemokine signaling pathway
pps04114  Oocyte meiosis
pps04140  Autophagy - animal
pps04211  Longevity regulating pathway
pps04213  Longevity regulating pathway - multiple species
pps04261  Adrenergic signaling in cardiomyocytes
pps04270  Vascular smooth muscle contraction
pps04310  Wnt signaling pathway
pps04340  Hedgehog signaling pathway
pps04371  Apelin signaling pathway
pps04530  Tight junction
pps04540  Gap junction
pps04611  Platelet activation
pps04713  Circadian entrainment
pps04714  Thermogenesis
pps04720  Long-term potentiation
pps04723  Retrograde endocannabinoid signaling
pps04724  Glutamatergic synapse
pps04725  Cholinergic synapse
pps04726  Serotonergic synapse
pps04727  GABAergic synapse
pps04728  Dopaminergic synapse
pps04740  Olfactory transduction
pps04742  Taste transduction
pps04750  Inflammatory mediator regulation of TRP channels
pps04910  Insulin signaling pathway
pps04911  Insulin secretion
pps04912  GnRH signaling pathway
pps04913  Ovarian steroidogenesis
pps04914  Progesterone-mediated oocyte maturation
pps04915  Estrogen signaling pathway
pps04916  Melanogenesis
pps04918  Thyroid hormone synthesis
pps04919  Thyroid hormone signaling pathway
pps04921  Oxytocin signaling pathway
pps04922  Glucagon signaling pathway
pps04923  Regulation of lipolysis in adipocytes
pps04924  Renin secretion
pps04925  Aldosterone synthesis and secretion
pps04926  Relaxin signaling pathway
pps04927  Cortisol synthesis and secretion
pps04928  Parathyroid hormone synthesis, secretion and action
pps04934  Cushing syndrome
pps04935  Growth hormone synthesis, secretion and action
pps04961  Endocrine and other factor-regulated calcium reabsorption
pps04962  Vasopressin-regulated water reabsorption
pps04970  Salivary secretion
pps04971  Gastric acid secretion
pps04976  Bile secretion
pps05012  Parkinson disease
pps05020  Prion disease
pps05030  Cocaine addiction
pps05031  Amphetamine addiction
pps05032  Morphine addiction
pps05034  Alcoholism
pps05146  Amoebiasis
pps05163  Human cytomegalovirus infection
pps05165  Human papillomavirus infection
pps05166  Human T-cell leukemia virus 1 infection
pps05200  Pathways in cancer
pps05203  Viral carcinogenesis
pps05205  Proteoglycans in cancer
pps05207  Chemical carcinogenesis - receptor activation
pps05414  Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:pps00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    100970917 (PRKACB)
   04014 Ras signaling pathway
    100970917 (PRKACB)
   04310 Wnt signaling pathway
    100970917 (PRKACB)
   04340 Hedgehog signaling pathway
    100970917 (PRKACB)
   04371 Apelin signaling pathway
    100970917 (PRKACB)
   04020 Calcium signaling pathway
    100970917 (PRKACB)
   04024 cAMP signaling pathway
    100970917 (PRKACB)
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    100970917 (PRKACB)
  09143 Cell growth and death
   04114 Oocyte meiosis
    100970917 (PRKACB)
  09144 Cellular community - eukaryotes
   04530 Tight junction
    100970917 (PRKACB)
   04540 Gap junction
    100970917 (PRKACB)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    100970917 (PRKACB)
   04062 Chemokine signaling pathway
    100970917 (PRKACB)
  09152 Endocrine system
   04911 Insulin secretion
    100970917 (PRKACB)
   04910 Insulin signaling pathway
    100970917 (PRKACB)
   04922 Glucagon signaling pathway
    100970917 (PRKACB)
   04923 Regulation of lipolysis in adipocytes
    100970917 (PRKACB)
   04912 GnRH signaling pathway
    100970917 (PRKACB)
   04913 Ovarian steroidogenesis
    100970917 (PRKACB)
   04915 Estrogen signaling pathway
    100970917 (PRKACB)
   04914 Progesterone-mediated oocyte maturation
    100970917 (PRKACB)
   04921 Oxytocin signaling pathway
    100970917 (PRKACB)
   04926 Relaxin signaling pathway
    100970917 (PRKACB)
   04935 Growth hormone synthesis, secretion and action
    100970917 (PRKACB)
   04918 Thyroid hormone synthesis
    100970917 (PRKACB)
   04919 Thyroid hormone signaling pathway
    100970917 (PRKACB)
   04928 Parathyroid hormone synthesis, secretion and action
    100970917 (PRKACB)
   04916 Melanogenesis
    100970917 (PRKACB)
   04924 Renin secretion
    100970917 (PRKACB)
   04925 Aldosterone synthesis and secretion
    100970917 (PRKACB)
   04927 Cortisol synthesis and secretion
    100970917 (PRKACB)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    100970917 (PRKACB)
   04270 Vascular smooth muscle contraction
    100970917 (PRKACB)
  09154 Digestive system
   04970 Salivary secretion
    100970917 (PRKACB)
   04971 Gastric acid secretion
    100970917 (PRKACB)
   04976 Bile secretion
    100970917 (PRKACB)
  09155 Excretory system
   04962 Vasopressin-regulated water reabsorption
    100970917 (PRKACB)
   04961 Endocrine and other factor-regulated calcium reabsorption
    100970917 (PRKACB)
  09156 Nervous system
   04724 Glutamatergic synapse
    100970917 (PRKACB)
   04727 GABAergic synapse
    100970917 (PRKACB)
   04725 Cholinergic synapse
    100970917 (PRKACB)
   04728 Dopaminergic synapse
    100970917 (PRKACB)
   04726 Serotonergic synapse
    100970917 (PRKACB)
   04720 Long-term potentiation
    100970917 (PRKACB)
   04723 Retrograde endocannabinoid signaling
    100970917 (PRKACB)
  09157 Sensory system
   04740 Olfactory transduction
    100970917 (PRKACB)
   04742 Taste transduction
    100970917 (PRKACB)
   04750 Inflammatory mediator regulation of TRP channels
    100970917 (PRKACB)
  09149 Aging
   04211 Longevity regulating pathway
    100970917 (PRKACB)
   04213 Longevity regulating pathway - multiple species
    100970917 (PRKACB)
  09159 Environmental adaptation
   04713 Circadian entrainment
    100970917 (PRKACB)
   04714 Thermogenesis
    100970917 (PRKACB)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    100970917 (PRKACB)
   05205 Proteoglycans in cancer
    100970917 (PRKACB)
   05207 Chemical carcinogenesis - receptor activation
    100970917 (PRKACB)
   05203 Viral carcinogenesis
    100970917 (PRKACB)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    100970917 (PRKACB)
   05163 Human cytomegalovirus infection
    100970917 (PRKACB)
   05165 Human papillomavirus infection
    100970917 (PRKACB)
  09174 Infectious disease: parasitic
   05146 Amoebiasis
    100970917 (PRKACB)
  09164 Neurodegenerative disease
   05012 Parkinson disease
    100970917 (PRKACB)
   05020 Prion disease
    100970917 (PRKACB)
  09165 Substance dependence
   05030 Cocaine addiction
    100970917 (PRKACB)
   05031 Amphetamine addiction
    100970917 (PRKACB)
   05032 Morphine addiction
    100970917 (PRKACB)
   05034 Alcoholism
    100970917 (PRKACB)
  09166 Cardiovascular disease
   05414 Dilated cardiomyopathy
    100970917 (PRKACB)
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    100970917 (PRKACB)
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    100970917 (PRKACB)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:pps01001]
    100970917 (PRKACB)
  09182 Protein families: genetic information processing
   03019 Messenger RNA biogenesis [BR:pps03019]
    100970917 (PRKACB)
   03036 Chromosome and associated proteins [BR:pps03036]
    100970917 (PRKACB)
Enzymes [BR:pps01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.11  cAMP-dependent protein kinase
     100970917 (PRKACB)
Protein kinases [BR:pps01001]
 Serine/threonine kinases: AGC group
  PKA family
   100970917 (PRKACB)
Messenger RNA biogenesis [BR:pps03019]
 Eukaryotic type
  mRNA surveillance and transport factors
   mRNA cycle factors
    Common to processing body (P body) and stress granule
     100970917 (PRKACB)
Chromosome and associated proteins [BR:pps03036]
 Eukaryotic type
  Centrosome formation proteins
   Kinases and associated factors
    100970917 (PRKACB)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr Kinase-like ABC1 Pkinase_C OST_P1
Other DBs
NCBI-GeneID: 100970917
NCBI-ProteinID: XP_014201384
Ensembl: ENSPPAG00000031832
Position
1:116625640..116786396
AA seq 357 aa
MSARKSSDASACSSSEISDSFVKEFLAKAKEDFLKKWENPTQNNAGLEDFERKKTLGTGS
FGRVMLVKHKATEQYYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVRLEYAFKDN
SNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLL
IDHQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAA
GYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVSDIKT
HKWFATTDWIAIYQRKVEAPFIPKFRGSGDTSNFDDYEEEDIRVSITEKCAKEFGEF
NT seq 1074 nt   +upstreamnt  +downstreamnt
atgagtgcacgcaaatcatcagatgcatctgcttgctcctcttcagaaatatctgattcc
tttgtgaaagagtttctagccaaagccaaagaagactttttgaaaaaatgggagaatcca
actcagaataatgccggacttgaagattttgaaaggaaaaaaacccttggaacaggttca
tttggaagagtcatgttggtaaaacacaaagccactgaacagtattatgccatgaagatc
ttagataagcagaaggttgttaaactgaagcaaatagagcatactttgaatgagaaaaga
atattacaggcagtgaattttcctttccttgttcgactggagtatgcttttaaggataat
tctaatttatacatggttatggaatatgtccctgggggtgaaatgttttcacatctaaga
agaattggaaggttcagtgagccccatgcacggttctatgcagctcagatagtgctaaca
ttcgagtacctccattcactagacctcatctacagagatctaaaacctgaaaatctctta
attgaccatcaaggctatatccaggtcacagactttgggtttgccaaaagagttaaaggc
agaacttggacattatgtggaactccagagtatttggctccagaaataattctcagcaag
ggctacaataaggcagtggattggtgggcattaggagtgctaatctatgaaatggcagct
ggctatcccccattctttgcagaccaaccaattcagatttatgaaaagattgtttctgga
aaggtccgattcccatcccacttcagttcagatctcaaggaccttctacggaacctgctg
caggtggatttgaccaagagatttggaaatctaaagaatggtgtcagtgatataaaaacc
cacaagtggtttgccacgacagattggattgctatttaccagaggaaggttgaagctcca
ttcataccaaagtttagaggctctggagataccagcaactttgatgactatgaagaagaa
gatatccgtgtctctataacagaaaaatgtgcaaaagaatttggtgaattttaa

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