KEGG   Pan paniscus (bonobo): 100973751
Entry
100973751         CDS       T02283                                 
Symbol
TYMS
Name
(RefSeq) thymidylate synthase
  KO
K00560  thymidylate synthase [EC:2.1.1.45]
Organism
pps  Pan paniscus (bonobo)
Pathway
pps00240  Pyrimidine metabolism
pps00670  One carbon pool by folate
pps01100  Metabolic pathways
pps01232  Nucleotide metabolism
pps01523  Antifolate resistance
Module
pps_M00938  Pyrimidine deoxyribonucleotide biosynthesis, UDP => dTTP
Brite
KEGG Orthology (KO) [BR:pps00001]
 09100 Metabolism
  09104 Nucleotide metabolism
   00240 Pyrimidine metabolism
    100973751 (TYMS)
  09108 Metabolism of cofactors and vitamins
   00670 One carbon pool by folate
    100973751 (TYMS)
 09160 Human Diseases
  09176 Drug resistance: antineoplastic
   01523 Antifolate resistance
    100973751 (TYMS)
Enzymes [BR:pps01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.45  thymidylate synthase
     100973751 (TYMS)
SSDB
Motif
Pfam: Thymidylat_synt
Other DBs
NCBI-GeneID: 100973751
NCBI-ProteinID: XP_003815680
Ensembl: ENSPPAG00000036745
UniProt: A0A2R9BCN0
Position
18:complement(13653085..13668478)
AA seq 313 aa
MPVAGSELPRRPLPPAAQERDAEPRPPHGELQYLGQIEHILRCGVRKDDRTGTGTLSVFG
MQARYSLRDEFPLLTTKRVFWKGVLEELLWFIKGSTNAKELSSKGVKIWDANGSRDFLDS
LGFSTREEGDLGPVYGFQWRHFGAEYRDMESDYSGQGVDQLQRVIDTIKSNPDDRRIIMC
AWNPRDLPLMALPPCHALCQFYVVNSELSCQLYQRSGDMGLGVPFNIASYALLTYMIAHI
TGLKPGDFIHTLGDAHIYLNHIEPLKIQLQREPRPFPKLKILRKVEKIDDFKAEDFQIEG
YNPHPTIKMEMAV
NT seq 942 nt   +upstreamnt  +downstreamnt
atgcctgtggccggctcggagctgccgcgccggcccttgccgcccgccgcacaggagcgg
gacgccgagccgcgtccgccgcacggggagctgcagtacctggggcagatcgaacacatc
ctccgctgcggcgtcaggaaggacgaccgcacgggcaccggcaccctgtcggtattcggc
atgcaggcgcgctacagcctgagagatgaatttcctctgctgacaaccaaacgtgtgttc
tggaagggtgttttggaggagttgctgtggtttatcaagggatccacaaatgctaaagag
ctgtcttccaagggagtgaaaatctgggatgccaatggatcccgagactttttggacagc
ctgggattctccaccagagaagaaggggacttgggcccagtttatggcttccagtggagg
cattttggggcagaatacagagatatggaatcagattattcaggacagggagttgaccaa
ctgcaaagagtgattgacaccatcaaatccaaccctgacgacagaagaatcatcatgtgc
gcttggaatccaagagatcttcctctgatggcgctgcctccatgccatgccctctgccag
ttctatgtggtgaacagtgagctgtcctgccagctgtaccagagatcgggagacatgggc
ctcggtgtgcctttcaacatcgccagctacgccctgctcacgtacatgattgcgcacatc
acgggcctgaagccaggtgactttatacacactttgggagatgcacatatttacctgaat
cacatcgagccactgaaaattcagcttcagcgagaacccagacctttcccaaagctcaag
attcttcgaaaagttgagaaaattgatgacttcaaagctgaagactttcagattgaaggg
tacaatccacatccaactattaaaatggaaatggctgtttag

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (6)   
   KEGG PATHWAY (5)   
   KEGG MODULE (1)   
Chemical substance (4)   
   KEGG COMPOUND (4)   
Chemical reaction (2)   
   KEGG ENZYME (1)   
   KEGG REACTION (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (5)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
Protein sequence (2)   
   UniProt (1)   
   RefSeq(pep) (1)   
DNA sequence (3)   
   RefSeq(nuc) (1)   
   GenBank (1)   
   EMBL (1)   
Protein domain (1)   
   Pfam (1)   
All databases (26)   

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