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Database: PROSITE
Entry: PS00068
LinkDB: PS00068
Original site: PS00068 
ID   MDH; PATTERN.
AC   PS00068;
DT   01-APR-1990 CREATED; 01-OCT-1993 DATA UPDATE; 20-JUN-2018 INFO UPDATE.
DE   Malate dehydrogenase active site signature.
PA   [LIVM]-T-[TRKMN]-L-D-x(2)-R-[STA]-x(3)-[LIVMFY].
NR   /RELEASE=2018_06,557713;
NR   /TOTAL=233(233); /POSITIVE=229(229); /UNKNOWN=0(0); /FALSE_POS=4(4);
NR   /FALSE_NEG=115; /PARTIAL=21;
CC   /TAXO-RANGE=??EP?; /MAX-REPEAT=1;
CC   /SITE=5,active_site; /SITE=7,active_site;
CC   /VERSION=1;
DR   Q54GE6    , MDHA_DICDI , T; P93819    , MDHC1_ARATH, T;
DR   P57106    , MDHC2_ARATH, T; Q9FJU0    , MDHC3_ARATH, T;
DR   Q9SML8    , MDHC_BETVU , T; Q3T145    , MDHC_BOVIN , T;
DR   P83778    , MDHC_CANAL , T; Q5ZME2    , MDHC_CHICK , T;
DR   Q54VM2    , MDHC_DICDI , T; Q04820    , MDHC_ECHGR , T;
DR   Q7YRU4    , MDHC_FELCA , T; P40925    , MDHC_HUMAN , T;
DR   Q08062    , MDHC_MAIZE , T; O48905    , MDHC_MEDSA , T;
DR   O24047    , MDHC_MESCR , T; P14152    , MDHC_MOUSE , T;
DR   Q7XDC8    , MDHC_ORYSJ , T; P11708    , MDHC_PIG   , T;
DR   O88989    , MDHC_RAT   , T; Q6PAB3    , MDHC_XENLA , T;
DR   Q6DIY9    , MDHC_XENTR , T; P22133    , MDHC_YEAST , T;
DR   Q43743    , MDHG1_BRANA, T; Q9XFW3    , MDHG2_BRANA, T;
DR   P19446    , MDHG_CITLA , T; P46488    , MDHG_CUCSA , T;
DR   Q42972    , MDHG_ORYSJ , T; P37228    , MDHG_SOYBN , T;
DR   Q9ZP06    , MDHM1_ARATH, T; Q9LKA3    , MDHM2_ARATH, T;
DR   Q32LG3    , MDHM_BOVIN , T; O02640    , MDHM_CAEEL , T;
DR   Q42686    , MDHM_CHLRE , T; P17783    , MDHM_CITLA , T;
DR   P46487    , MDHM_EUCGU , T; K0J107    , MDHM_FELCA , T;
DR   P83373    , MDHM_FRAAN , T; P40926    , MDHM_HUMAN , T;
DR   Q4R568    , MDHM_MACFA , T; P08249    , MDHM_MOUSE , T;
DR   P00346    , MDHM_PIG   , T; Q5NVR2    , MDHM_PONAB , T;
DR   P04636    , MDHM_RAT   , T; P17505    , MDHM_YEAST , T;
DR   Q8H1E2    , MDHNP_ARATH, T; P17606    , MDHP1_SORBI, T;
DR   P37229    , MDHP2_SORBI, T; Q9SN86    , MDHP_ARATH , T;
DR   P46489    , MDHP_FLABI , T; P15719    , MDHP_MAIZE , T;
DR   O48902    , MDHP_MEDSA , T; Q05145    , MDHP_MESCR , T;
DR   P21528    , MDHP_PEA   , T; P52426    , MDHP_SPIOL , T;
DR   P32419    , MDHP_YEAST , T; O82399    , MDHX1_ARATH, T;
DR   Q9ZP05    , MDHX2_ARATH, T; Q5U907    , MDH_ACTSZ  , T;
DR   A0KG16    , MDH_AERHH  , T; A4SIV0    , MDH_AERS4  , T;
DR   B2UKY5    , MDH_AKKM8  , T; Q0VQ52    , MDH_ALCBS  , T;
DR   B6EL39    , MDH_ALISL  , T; Q0ABE6    , MDH_ALKEH  , T;
DR   B3PHI3    , MDH_CELJU  , T; A8AQC8    , MDH_CITK8  , T;
DR   Q47VL0    , MDH_COLP3  , T; B6J7Q0    , MDH_COXB1  , T;
DR   B6IZN7    , MDH_COXB2  , T; A9KFT9    , MDH_COXBN  , T;
DR   A9NDV1    , MDH_COXBR  , T; Q83C87    , MDH_COXBU  , T;
DR   A7MNR3    , MDH_CROS8  , T; Q6A6Z5    , MDH_CUTAK  , T;
DR   A7ZSD0    , MDH_ECO24  , T; B7UJW8    , MDH_ECO27  , T;
DR   B7MBZ7    , MDH_ECO45  , T; B7LHU4    , MDH_ECO55  , T;
DR   P61891    , MDH_ECO57  , T; B5YSW2    , MDH_ECO5E  , T;
DR   B7NKU9    , MDH_ECO7I  , T; B7N0M1    , MDH_ECO81  , T;
DR   B7M0U8    , MDH_ECO8A  , T; C4ZSX4    , MDH_ECOBW  , T;
DR   B1XHK9    , MDH_ECODH  , T; A8A545    , MDH_ECOHS  , T;
DR   A1AGC9    , MDH_ECOK1  , T; Q0TCN0    , MDH_ECOL5  , T;
DR   P61890    , MDH_ECOL6  , T; B1IQP3    , MDH_ECOLC  , T;
DR   P61889    , MDH_ECOLI  , T; B7NDL4    , MDH_ECOLU  , T;
DR   B6I1V4    , MDH_ECOSE  , T; B1LGK2    , MDH_ECOSM  , T;
DR   Q1R6A3    , MDH_ECOUT  , T; C5BF98    , MDH_EDWI9  , T;
DR   A4WF48    , MDH_ENT38  , T; B2VGW7    , MDH_ERWT9  , T;
DR   B7LRL0    , MDH_ESCF3  , T; Q0RE66    , MDH_FRAAA  , T;
DR   Q2J7E7    , MDH_FRACC  , T; Q7VP41    , MDH_HAEDU  , T;
DR   Q4QL89    , MDH_HAEI8  , T; A5UCQ1    , MDH_HAEIE  , T;
DR   A5UIX3    , MDH_HAEIG  , T; P44427    , MDH_HAEIN  , T;
DR   Q0I491    , MDH_HAES1  , T; A1WV94    , MDH_HALHL  , T;
DR   B0UUR6    , MDH_HISS2  , T; Q5R030    , MDH_IDILO  , T;
DR   P61894    , MDH_KLEOX  , T; B5XSQ7    , MDH_KLEP3  , T;
DR   A6TEQ3    , MDH_KLEP7  , T; P61896    , MDH_KLEVA  , T;
DR   B2GKC8    , MDH_KOCRD  , T; Q5X2T6    , MDH_LEGPA  , T;
DR   A5IEF4    , MDH_LEGPC  , T; Q5ZT13    , MDH_LEGPH  , T;
DR   Q5WU94    , MDH_LEGPL  , T; Q04RS5    , MDH_LEPBJ  , T;
DR   Q051U6    , MDH_LEPBL  , T; P61975    , MDH_LEPIC  , T;
DR   Q8F4A2    , MDH_LEPIN  , T; Q65T37    , MDH_MANSM  , T;
DR   Q60B71    , MDH_METCA  , T; Q6AW21    , MDH_MORJA  , T;
DR   Q6AW23    , MDH_MORMI  , T; Q7X3X5    , MDH_MORS2  , T;
DR   P48364    , MDH_MORS5  , T; A0QCI6    , MDH_MYCA1  , T;
DR   P0A5J7    , MDH_MYCBO  , T; A1KI28    , MDH_MYCBP  , T;
DR   C1AMN4    , MDH_MYCBT  , T; P50917    , MDH_MYCLE  , T;
DR   B2HRH5    , MDH_MYCMM  , T; P61976    , MDH_MYCPA  , T;
DR   A5U1T8    , MDH_MYCTA  , T; P9WK12    , MDH_MYCTO  , T;
DR   P9WK13    , MDH_MYCTU  , T; A0PVV1    , MDH_MYCUA  , T;
DR   Q5YTI1    , MDH_NOCFA  , T; A1SMP3    , MDH_NOCSJ  , T;
DR   A1R2B5    , MDH_PAEAT  , T; Q6MAA3    , MDH_PARUW  , T;
DR   Q9CN86    , MDH_PASMU  , T; Q6D9D1    , MDH_PECAS  , T;
DR   P61897    , MDH_PECCC  , T; C6DKH1    , MDH_PECCP  , T;
DR   Q7MYW9    , MDH_PHOLL  , T; P37226    , MDH_PHOPR  , T;
DR   B4F2A1    , MDH_PROMH  , T; Q15YH0    , MDH_PSEA6  , T;
DR   Q3IFH4    , MDH_PSEHT  , T; Q4FQU7    , MDH_PSYA2  , T;
DR   Q1Q932    , MDH_PSYCK  , T; A1SRP8    , MDH_PSYIN  , T;
DR   P61895    , MDH_RAOTE  , T; Q0S365    , MDH_RHOJR  , T;
DR   C1B155    , MDH_RHOOB  , T; Q1AWH4    , MDH_RUBXD  , T;
DR   A4FFX3    , MDH_SACEN  , T; B5F7L9    , MDH_SALA4  , T;
DR   A9MNX5    , MDH_SALAR  , T; Q57JA9    , MDH_SALCH  , T;
DR   B5FIT7    , MDH_SALDC  , T; B5R0N2    , MDH_SALEP  , T;
DR   B5REV7    , MDH_SALG2  , T; B4TJT3    , MDH_SALHS  , T;
DR   Q59838    , MDH_SALMU  , T; B4T769    , MDH_SALNS  , T;
DR   Q7WS85    , MDH_SALPA  , T; A9N855    , MDH_SALPB  , T;
DR   C0PZQ4    , MDH_SALPC  , T; B5BGR3    , MDH_SALPK  , T;
DR   B4TWK9    , MDH_SALSV  , T; Q8Z3E0    , MDH_SALTI  , T;
DR   P25077    , MDH_SALTY  , T; A1S3C4    , MDH_SHEAM  , T;
DR   B8EB55    , MDH_SHEB2  , T; A3D075    , MDH_SHEB5  , T;
DR   A6WSM1    , MDH_SHEB8  , T; A9L340    , MDH_SHEB9  , T;
DR   Q12R11    , MDH_SHEDO  , T; Q07YA5    , MDH_SHEFN  , T;
DR   B0TUH8    , MDH_SHEHH  , T; A3QB91    , MDH_SHELP  , T;
DR   P82177    , MDH_SHEON  , T; A8H0U0    , MDH_SHEPA  , T;
DR   A4YAE8    , MDH_SHEPC  , T; B8CSY7    , MDH_SHEPW  , T;
DR   A0L113    , MDH_SHESA  , T; A8FRU0    , MDH_SHESH  , T;
DR   Q0HEW2    , MDH_SHESM  , T; Q0HZ38    , MDH_SHESR  , T;
DR   A1RFX8    , MDH_SHESW  , T; B1KGG7    , MDH_SHEWM  , T;
DR   B2U1U9    , MDH_SHIB3  , T; Q31WA4    , MDH_SHIBS  , T;
DR   Q32BA3    , MDH_SHIDS  , T; Q0T052    , MDH_SHIF8  , T;
DR   Q83Q04    , MDH_SHIFL  , T; Q3YX11    , MDH_SHISS  , T;
DR   Q82HS2    , MDH_STRAW  , T; Q9K3J3    , MDH_STRCO  , T;
DR   B1W3N4    , MDH_STRGG  , T; Q47TT4    , MDH_THEFY  , T;
DR   P61977    , MDH_THET2  , T; Q5SKV7    , MDH_THET8  , T;
DR   P10584    , MDH_THETH  , T; Q9FSF0    , MDH_TOBAC  , T;
DR   A7MWD3    , MDH_VIBCB  , T; Q9KUT3    , MDH_VIBCH  , T;
DR   Q5E875    , MDH_VIBF1  , T; B5FGF5    , MDH_VIBFM  , T;
DR   Q9L8F6    , MDH_VIBMI  , T; Q87SU7    , MDH_VIBPA  , T;
DR   B7VID0    , MDH_VIBTL  , T; Q8DEC2    , MDH_VIBVU  , T;
DR   Q7MP97    , MDH_VIBVY  , T; A1JIV0    , MDH_YERE8  , T;
DR   A7FMU2    , MDH_YERP3  , T; Q1CBY7    , MDH_YERPA  , T;
DR   B2K2N5    , MDH_YERPB  , T; P61892    , MDH_YERPE  , T;
DR   A9R584    , MDH_YERPG  , T; Q1CEJ3    , MDH_YERPN  , T;
DR   A4TRK3    , MDH_YERPP  , T; P0C7R5    , MDH_YERPS  , T;
DR   B1JMK1    , MDH_YERPY  , T;
DR   P86074    , MDHM_CAPAA , P; P84209    , MDHM_IMPCY , P;
DR   P37227    , MDHM_SCHMA , P; P82816    , MDHM_TOBAC , P;
DR   P80540    , MDH_ACIDE  , P; P19977    , MDH_ACTMI  , P;
DR   P80537    , MDH_BURCE  , P; P80539    , MDH_DELAC  , P;
DR   P19978    , MDH_KIBAR  , P; P0C1G4    , MDH_KLEPN  , P;
DR   P0C1G5    , MDH_KLEPR  , P; P19979    , MDH_MICGL  , P;
DR   P10887    , MDH_NITAL  , P; P19980    , MDH_PHEIM  , P;
DR   P19981    , MDH_PLAVE  , P; P85920    , MDH_PSEMZ  , P;
DR   P80541    , MDH_STEMA  , P; P19982    , MDH_STRAR  , P;
DR   P19983    , MDH_STRRS  , P; P33163    , MDH_THEAL  , P;
DR   P80538    , MDH_VOGIN  , P;
DR   Q2T7J2    , MDH1_BURTA , N; A4JKE6    , MDH1_BURVG , N;
DR   Q21XH1    , MDH1_RHOFT , N; Q2T4T8    , MDH2_BURTA , N;
DR   A4JM71    , MDH2_BURVG , N; Q21VT3    , MDH2_RHOFT , N;
DR   Q43744    , MDHM_BRANA , N; A1TP96    , MDH_ACIAC  , N;
DR   Q6F7X1    , MDH_ACIAD  , N; B7GW58    , MDH_ACIB3  , N;
DR   B7I9D2    , MDH_ACIB5  , N; B2HZ52    , MDH_ACIBC  , N;
DR   B0VQX5    , MDH_ACIBS  , N; A3M928    , MDH_ACIBT  , N;
DR   B0V6R7    , MDH_ACIBY  , N; A5G320    , MDH_ACICJ  , N;
DR   B9MBP0    , MDH_ACIET  , N; A1W9K7    , MDH_ACISJ  , N;
DR   A3N1U6    , MDH_ACTP2  , N; B3H269    , MDH_ACTP7  , N;
DR   B0BQN0    , MDH_ACTPJ  , N; Q9ZF99    , MDH_AQUAR  , N;
DR   Q5NYA9    , MDH_AROAE  , N; A1K5Q9    , MDH_AZOSB  , N;
DR   P61973    , MDH_BDEBA  , N; Q2L068    , MDH_BORA1  , N;
DR   Q7WD94    , MDH_BORBR  , N; Q7W5Q8    , MDH_BORPA  , N;
DR   A9IIS3    , MDH_BORPD  , N; Q7VW97    , MDH_BORPE  , N;
DR   Q1BM38    , MDH_BURCA  , N; B1K394    , MDH_BURCC  , N;
DR   A0AZ43    , MDH_BURCH  , N; B4EFB0    , MDH_BURCJ  , N;
DR   Q0BAF9    , MDH_BURCM  , N; Q393V1    , MDH_BURL3  , N;
DR   A9AMD5    , MDH_BURM1  , N; A3MBR2    , MDH_BURM7  , N;
DR   A2S105    , MDH_BURM9  , N; Q62AG8    , MDH_BURMA  , N;
DR   A1UZ10    , MDH_BURMS  , N; A3P7Q9    , MDH_BURP0  , N;
DR   Q3JKE9    , MDH_BURP1  , N; A3NM97    , MDH_BURP6  , N;
DR   P80536    , MDH_BURPS  , N; Q5L5E3    , MDH_CHLAB  , N;
DR   Q822E9    , MDH_CHLCV  , N; Q255I4    , MDH_CHLFF  , N;
DR   Q9PK18    , MDH_CHLMU  , N; Q9Z6N1    , MDH_CHLPN  , N;
DR   B0B7U5    , MDH_CHLT2  , N; Q3KLX8    , MDH_CHLTA  , N;
DR   B0BC10    , MDH_CHLTB  , N; O84381    , MDH_CHLTR  , N;
DR   Q7NZ60    , MDH_CHRVO  , N; P61974    , MDH_CORDI  , N;
DR   Q8FN62    , MDH_COREF  , N; A4QGA0    , MDH_CORGB  , N;
DR   Q8NN33    , MDH_CORGL  , N; Q4JWV0    , MDH_CORJK  , N;
DR   Q1LKG0    , MDH_CUPMC  , N; Q0K8F5    , MDH_CUPNH  , N;
DR   Q46YU4    , MDH_CUPNJ  , N; B3R570    , MDH_CUPTR  , N;
DR   Q47C34    , MDH_DECAR  , N; C1CY73    , MDH_DEIDV  , N;
DR   Q1IWC9    , MDH_DEIGD  , N; Q9RXI8    , MDH_DEIRA  , N;
DR   A9BVK0    , MDH_DELAS  , N; Q6AQI3    , MDH_DESPS  , N;
DR   Q5FGT9    , MDH_EHRRG  , N; B8F5K4    , MDH_HAEPS  , N;
DR   A4G5Z9    , MDH_HERAR  , N; A6SY47    , MDH_JANMA  , N;
DR   C1DB66    , MDH_LARHH  , N; B0SF41    , MDH_LEPBA  , N;
DR   B0SN74    , MDH_LEPBP  , N; B1Y8A3    , MDH_LEPCP  , N;
DR   A0L5T9    , MDH_MAGMM  , N; A2SHT9    , MDH_METPP  , N;
DR   A1T9L9    , MDH_MYCVP  , N; Q0AFK6    , MDH_NITEC  , N;
DR   Q82WB9    , MDH_NITEU  , N; Q2YAQ4    , MDH_NITMU  , N;
DR   B2JQD2    , MDH_PARP8  , N; B2T9P8    , MDH_PARPJ  , N;
DR   Q13S42    , MDH_PARXL  , N; A4SWW0    , MDH_POLAQ  , N;
DR   A1VRQ1    , MDH_POLNA  , N; B1XV63    , MDH_POLNS  , N;
DR   Q126N9    , MDH_POLSJ  , N; A5WGM2    , MDH_PSYWF  , N;
DR   B2U705    , MDH_RALPJ  , N; Q8XXW5    , MDH_RALSO  , N;
DR   Q21K60    , MDH_SACD2  , N; A8G8Y7    , MDH_SERP5  , N;
DR   B4SLI5    , MDH_STRM5  , N; B2FQL8    , MDH_STRMK  , N;
DR   A0LFF8    , MDH_SYNFM  , N; C5BU70    , MDH_TERTT  , N;
DR   C5CSI5    , MDH_VARPS  , N; A1WR02    , MDH_VEREI  , N;
DR   Q5GT41    , MDH_WOLTR  , N; Q8PNP8    , MDH_XANAC  , N;
DR   Q3BWU8    , MDH_XANC5  , N; Q4URH2    , MDH_XANC8  , N;
DR   B0RU49    , MDH_XANCB  , N; Q8PC25    , MDH_XANCP  , N;
DR   Q2P736    , MDH_XANOM  , N; B2SMP6    , MDH_XANOP  , N;
DR   Q5H496    , MDH_XANOR  , N; B2I8M1    , MDH_XYLF2  , N;
DR   Q9PE17    , MDH_XYLFA  , N; B0U5Q1    , MDH_XYLFM  , N;
DR   Q87E35    , MDH_XYLFT  , N;
DR   Q7P0F0    , HIS4_CHRVO , F; Q31E65    , HIS4_HYDCU , F;
DR   Q84JW1    , PX11E_ARATH, F; Q0PV50    , TLR3_BOSTR , F;
3D   1BDM; 1BMD; 1CIV; 1EMD; 1IZ9; 1MLD; 1SEV; 1SMK; 1WZE; 1WZI; 1Y7T; 2CMD;
3D   2CVQ; 2DFD; 2PWZ; 3HHP; 4E0B; 4KDE; 4KDF; 4MDH; 4TVO; 4WLE; 4WLF; 4WLN;
3D   4WLO; 4WLU; 4WLV; 5KKA; 5KVV; 5MDH; 5NUE; 5NUF; 6AOO; 6BAL; 7MDH;
PR   PRU10004;
DO   PDOC00066;
//
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