GenomeNet

Database: PROSITE
Entry: PS00138
LinkDB: PS00138
Original site: PS00138 
ID   SUBTILASE_SER; PATTERN.
AC   PS00138;
DT   01-APR-1990 CREATED; 01-APR-2006 DATA UPDATE; 13-NOV-2019 INFO UPDATE.
DE   Serine proteases, subtilase family, serine active site.
PA   G-T-S-x-[SA]-x-P-x-{L}-[STAVC]-[AG].
NR   /RELEASE=2019_10,561356;
NR   /TOTAL=338(335); /POSITIVE=307(307); /UNKNOWN=0(0); /FALSE_POS=31(28);
NR   /FALSE_NEG=0; /PARTIAL=7;
CC   /TAXO-RANGE=A?EP?; /MAX-REPEAT=4;
CC   /SITE=3,active_site;
CC   /VERSION=2;
DR   P09230    , AEP_YARLI  , T; Q9ZSP5    , AIR3_ARATH , T;
DR   B0Y473    , ALP2_ASPFC , T; P87184    , ALP2_ASPFU , T;
DR   P29118    , ALP_ACRCH  , T; Q03420    , ALP_HYPAT  , T;
DR   Q68GV9    , ALP_LECPS  , T; O31788    , APRX_BACSU , T;
DR   P08594    , AQL1_THEAQ , T; R4IR27    , ASES_SARSR , T;
DR   P31339    , ASPA_AERSA , T; P51559    , BLI4_CAEEL , T;
DR   A0A044RE18, BLI_ONCVO  , T; P42779    , BPRV_DICNO , T;
DR   P42780    , BPRX_DICNO , T; P58099    , C5AP_STRP1 , T;
DR   P0DD34    , C5AP_STRP3 , T; Q5X9R0    , C5AP_STRP6 , T;
DR   Q8NZ80    , C5AP_STRP8 , T; P0DD35    , C5AP_STRPQ , T;
DR   P15926    , C5AP_STRPY , T; B7ZK61    , CH901_DAVTA, T;
DR   B3V0K8    , CL401_COCLU, T; Q9LNU1    , CRSP_ARATH , T;
DR   Q39547    , CUCM1_CUCME, T; P29138    , CUDP_METAN , T;
DR   P27693    , ELYA_BACAO , T; P41362    , ELYA_BACCS , T;
DR   P41363    , ELYA_BACHD , T; P20724    , ELYA_BACYA , T;
DR   P30199    , EPIP_STAEP , T; P23314    , EXPR_XANCP , T;
DR   P86876    , FIBR2_HEDJA, T; O17798    , FKPC1_CAEEL, T;
DR   Q93LQ6    , FLS_FERPE  , T; P26016    , FUR11_DROME, T;
DR   P30430    , FUR1C_DROME, T; P30432    , FUR2_DROME , T;
DR   P29119    , FURI1_XENLA, T; P09958    , FURIN_HUMAN, T;
DR   P23188    , FURIN_MOUSE, T; P23377    , FURIN_RAT  , T;
DR   I3R794    , HLY_HALMT  , T; P29143    , HLY_NATA1  , T;
DR   P11018    , ISP1_BACSU , T; P40903    , ISP6_SCHPO , T;
DR   P29140    , ISP_BACCS  , T; P29139    , ISP_PAEPO  , T;
DR   P09231    , KEX1A_KLULA, T; O13359    , KEX2_CANAW , T;
DR   P13134    , KEX2_YEAST , T; Q09175    , KRP1_SCHPO , T;
DR   Q9Z2A8    , MBTP1_CRIGR, T; Q14703    , MBTP1_HUMAN, T;
DR   Q9WTZ2    , MBTP1_MOUSE, T; Q9WTZ3    , MBTP1_RAT  , T;
DR   I6YC58    , MYCP4_MYCTU, T; Q9GLR1    , NEC1_BOVIN , T;
DR   P29120    , NEC1_HUMAN , T; P63239    , NEC1_MOUSE , T;
DR   P63240    , NEC1_MUSCO , T; P28840    , NEC1_RAT   , T;
DR   Q9GLR0    , NEC2_BOVIN , T; G5ECN9    , NEC2_CAEEL , T;
DR   P16519    , NEC2_HUMAN , T; P21661    , NEC2_MOUSE , T;
DR   Q03333    , NEC2_PIG   , T; Q5REC2    , NEC2_PONAB , T;
DR   P28841    , NEC2_RAT   , T; P29146    , NECA_HYDVU , T;
DR   P29145    , NECB_HYDVU , T; Q5RLZ1    , NEP_NATMA  , T;
DR   A1CIA7    , ORYZ_ASPCL , T; B0Y708    , ORYZ_ASPFC , T;
DR   P35211    , ORYZ_ASPFL , T; B8N106    , ORYZ_ASPFN , T;
DR   P28296    , ORYZ_ASPFU , T; P12547    , ORYZ_ASPOR , T;
DR   Q00208    , ORYZ_EMENI , T; A1CWF3    , ORYZ_NEOFI , T;
DR   P16271    , P1P_LACLC  , T; P15293    , P2P_LACLC  , T;
DR   Q02470    , P2P_LACPA  , T; P15292    , P3P_LACLS  , T;
DR   Q8NKG0    , PCH13_PENCH, T; Q9HF04    , PCH18_PENCH, T;
DR   Q6UW60    , PCSK4_HUMAN, T; P29121    , PCSK4_MOUSE, T;
DR   Q78EH2    , PCSK4_RAT  , T; Q9NJ15    , PCSK5_BRACL, T;
DR   Q92824    , PCSK5_HUMAN, T; Q04592    , PCSK5_MOUSE, T;
DR   P41413    , PCSK5_RAT  , T; P29122    , PCSK6_HUMAN, T;
DR   Q63415    , PCSK6_RAT  , T; Q16549    , PCSK7_HUMAN, T;
DR   Q61139    , PCSK7_MOUSE, T; Q62849    , PCSK7_RAT  , T;
DR   Q9URR2    , PEN13_PENCH, T; Q9P8G3    , PEN18_PENCH, T;
DR   Q9Y749    , PENC1_PENCI, T; Q9Y755    , PENC2_PENCI, T;
DR   P33295    , PEPC_ASPNG , T; P72186    , PLS_PYRFU  , T;
DR   Q59149    , PRCA_NOSS1 , T; P23916    , PRCA_TRIV2 , T;
DR   P16588    , PROA_VIBAL , T; P09232    , PRTB_YEAST , T;
DR   P06873    , PRTK_PARAQ , T; Q99405    , PRTM_BACSK , T;
DR   P23653    , PRTR_PARAQ , T; P09489    , PRTS_SERMA , T;
DR   P20015    , PRTT_PARAQ , T; Q9UTS0    , PSP3_SCHPO , T;
DR   Q32ZM1    , RM201_RHOMI, T; P25381    , RRT12_YEAST, T;
DR   Q84WS0    , SBT11_ARATH, T; O64495    , SBT12_ARATH, T;
DR   Q9FLI4    , SBT13_ARATH, T; Q9LVJ1    , SBT14_ARATH, T;
DR   Q9LUM3    , SBT15_ARATH, T; O49607    , SBT16_ARATH, T;
DR   O65351    , SBT17_ARATH, T; Q9ZUF6    , SBT18_ARATH, T;
DR   Q9FHA4    , SBT19_ARATH, T; I1N462    , SBT1_SOYBN , T;
DR   Q9SA75    , SBT21_ARATH, T; Q9SUN6    , SBT22_ARATH, T;
DR   Q9FI12    , SBT23_ARATH, T; F4HYR6    , SBT24_ARATH, T;
DR   O64481    , SBT25_ARATH, T; Q9SZV5    , SBT26_ARATH, T;
DR   F4JJH4    , SBT31_ARATH, T; Q9MAP4    , SBT32_ARATH, T;
DR   Q9MAP5    , SBT33_ARATH, T; F4HPF1    , SBT34_ARATH, T;
DR   Q9MAP7    , SBT35_ARATH, T; Q8L7I2    , SBT36_ARATH, T;
DR   Q9SZY2    , SBT37_ARATH, T; Q9SZY3    , SBT38_ARATH, T;
DR   Q9ZSB0    , SBT39_ARATH, T; Q9ZSB1    , SBT3A_ARATH, T;
DR   Q1PDX5    , SBT3B_ARATH, T; F4JJH5    , SBT3C_ARATH, T;
DR   Q8GUK4    , SBT3D_ARATH, T; Q9SVT4    , SBT3E_ARATH, T;
DR   F4JJL8    , SBT3F_ARATH, T; Q8GWX9    , SBT3G_ARATH, T;
DR   Q9C7U8    , SBT3H_ARATH, T; Q9STQ2    , SBT3I_ARATH, T;
DR   O82777    , SBT3_SOLLC , T; F4IG09    , SBT41_ARATH, T;
DR   O23357    , SBT42_ARATH, T; Q9FIF8    , SBT43_ARATH, T;
DR   Q9FGU3    , SBT44_ARATH, T; F4JA91    , SBT45_ARATH, T;
DR   Q9STF7    , SBT46_ARATH, T; F4KGD4    , SBT47_ARATH, T;
DR   Q9FIM6    , SBT48_ARATH, T; Q9FIM5    , SBT49_ARATH, T;
DR   Q9FIM8    , SBT4A_ARATH, T; Q9FIG1    , SBT4B_ARATH, T;
DR   Q8L7D2    , SBT4C_ARATH, T; Q9FIG2    , SBT4D_ARATH, T;
DR   Q9LLL8    , SBT4E_ARATH, T; Q9LZS6    , SBT4F_ARATH, T;
DR   F4HSQ2    , SBT51_ARATH, T; F4JXC5    , SBT54_ARATH, T;
DR   F4KEL0    , SBT55_ARATH, T; Q9FK76    , SBT56_ARATH, T;
DR   Q0WUG6    , SBT61_ARATH, T; P80146    , SEPR_THESR , T;
DR   Q9Y778    , SMP1_MAGPO , T; G1X8P8    , SPAZ_ARTOA , T;
DR   G3FNQ9    , SPAZ_ARTOL , T; Q8SQJ3    , SPL1_ENCCU , T;
DR   P58371    , SPM1_MAGO7 , T; P31631    , SSA1_MANHA , T;
DR   C5P1W9    , SU11A_COCP7, T; C5PFR5    , SU11B_COCP7, T;
DR   D4AQG0    , SUB10_ARTBC, T; C5FX37    , SUB10_ARTOC, T;
DR   D4DIS6    , SUB10_TRIVH, T; D4AQA9    , SUB12_ARTBC, T;
DR   E4UY04    , SUB12_ARTGP, T; D4D1U5    , SUB12_TRIVH, T;
DR   D4AKU9    , SUB1_ARTBC , T; Q64K30    , SUB1_ARTBE , T;
DR   E4UPZ4    , SUB1_ARTGP , T; C5FPS1    , SUB1_ARTOC , T;
DR   Q8J0D9    , SUB1_ARTOT , T; L8G6I7    , SUB1_PSED2 , T;
DR   B6VA84    , SUB1_TRIEQ , T; Q69F58    , SUB1_TRIRU , T;
DR   B8XGQ4    , SUB1_TRITO , T; Q5VJ77    , SUB1_TRIVC , T;
DR   D4DIW9    , SUB1_TRIVH , T; C5P6D1    , SUB2A_COCP7, T;
DR   C5P906    , SUB2B_COCP7, T; C5NZ70    , SUB2C_COCP7, T;
DR   D4AZ75    , SUB2_ARTBC , T; Q64K35    , SUB2_ARTBE , T;
DR   E4UZP9    , SUB2_ARTGP , T; C5G168    , SUB2_ARTOC , T;
DR   Q8J0D8    , SUB2_ARTOT , T; Q9RYM8    , SUB2_DEIRA , T;
DR   L8FSM5    , SUB2_PSED2 , T; B6VA85    , SUB2_TRIEQ , T;
DR   Q69F57    , SUB2_TRIRU , T; B8XGQ5    , SUB2_TRITO , T;
DR   Q5VJ76    , SUB2_TRIVC , T; D4DLI5    , SUB2_TRIVH , T;
DR   D4AWY5    , SUB3_ARTBC , T; Q64K34    , SUB3_ARTBE , T;
DR   E4UN97    , SUB3_ARTGP , T; C5FMY5    , SUB3_ARTOC , T;
DR   Q8J0D7    , SUB3_ARTOT , T; L8GD75    , SUB3_PSED2 , T;
DR   B6VA86    , SUB3_TRIEQ , T; Q69F56    , SUB3_TRIRU , T;
DR   B8XGQ6    , SUB3_TRITO , T; Q5VJ75    , SUB3_TRIVC , T;
DR   D4DLA2    , SUB3_TRIVH , T; C5PCB1    , SUB4A_COCP7, T;
DR   C5P6L5    , SUB4C_COCP7, T; D4AXW3    , SUB4_ARTBC , T;
DR   Q64K33    , SUB4_ARTBE , T; E4UWA4    , SUB4_ARTGP , T;
DR   C5FXZ6    , SUB4_ARTOC , T; A7UKV6    , SUB4_TRIEQ , T;
DR   Q69F35    , SUB4_TRIRU , T; B8XGQ7    , SUB4_TRITO , T;
DR   Q5VJ74    , SUB4_TRIVC , T; D4D6Q4    , SUB4_TRIVH , T;
DR   D4B194    , SUB5_ARTBC , T; Q64K32    , SUB5_ARTBE , T;
DR   E4V2L6    , SUB5_ARTGP , T; C5G1D1    , SUB5_ARTOC , T;
DR   B6VA87    , SUB5_TRIEQ , T; Q69F34    , SUB5_TRIRU , T;
DR   B8XGQ8    , SUB5_TRITO , T; Q5VJ73    , SUB5_TRIVC , T;
DR   D4D0F5    , SUB5_TRIVH , T; D4ALV9    , SUB6_ARTBC , T;
DR   Q64K31    , SUB6_ARTBE , T; E4V4J8    , SUB6_ARTGP , T;
DR   C5FQI3    , SUB6_ARTOC , T; A1XIH0    , SUB6_TRIEQ , T;
DR   Q9UW97    , SUB6_TRIRU , T; A1XIH1    , SUB6_TRISD , T;
DR   Q8J077    , SUB6_TRISH , T; Q3ZEJ8    , SUB6_TRITO , T;
DR   Q5VJ72    , SUB6_TRIVC , T; D4D5H3    , SUB6_TRIVH , T;
DR   C5PGK9    , SUB7A_COCP7, T; C5PCX1    , SUB7B_COCP7, T;
DR   D4APA9    , SUB7_ARTBC , T; Q64K36    , SUB7_ARTBE , T;
DR   E4V2V9    , SUB7_ARTGP , T; C5FJA5    , SUB7_ARTOC , T;
DR   A1XIH3    , SUB7_TRIEQ , T; Q8NID9    , SUB7_TRIRU , T;
DR   A1XIH4    , SUB7_TRITO , T; Q5VJ71    , SUB7_TRIVC , T;
DR   D4CZQ4    , SUB7_TRIVH , T; A1XIH6    , SUB7_TRIVO , T;
DR   D4AX50    , SUB8_ARTBC , T; C5FII2    , SUB8_ARTOC , T;
DR   C5P4Z8    , SUB8_COCP7 , T; D4DKQ4    , SUB8_TRIVH , T;
DR   D4B5N1    , SUB9_ARTBC , T; E4UTU7    , SUB9_ARTGP , T;
DR   C5FH27    , SUB9_ARTOC , T; C5P5Q3    , SUB9_COCP7 , T;
DR   D4D674    , SUB9_TRIVH , T; P29599    , SUBB_BACLE , T;
DR   P00780    , SUBC_BACLI , T; P00781    , SUBD_BACLI , T;
DR   P16396    , SUBE_BACSU , T; P16397    , SUBF_BACSU , T;
DR   P35835    , SUBN_BACNA , T; P29600    , SUBS_BACLE , T;
DR   P00782    , SUBT_BACAM , T; P07518    , SUBT_BACPU , T;
DR   P28842    , SUBT_BACS9 , T; P00783    , SUBT_BACSA , T;
DR   P04189    , SUBT_BACSU , T; P29142    , SUBT_GEOSE , T;
DR   P29141    , SUBV_BACSU , T; P54683    , TAGB_DICDI , T;
DR   Q8T9W1    , TAGD_DICDI , T; Q45670    , THES_BACSJ , T;
DR   P04072    , THET_THEVU , T; Q5JIZ5    , TKSP_THEKO , T;
DR   P58502    , TKSU_THEKO , T; A5PK39    , TPP2_BOVIN , T;
DR   Q09541    , TPP2_CAEEL , T; Q9V6K1    , TPP2_DROME , T;
DR   P29144    , TPP2_HUMAN , T; Q64514    , TPP2_MOUSE , T;
DR   Q64560    , TPP2_RAT   , T; Q9UT05    , TPP2_SCHPO , T;
DR   F4JVN6    , TPPII_ARATH, T; Q6ESI7    , TPPII_ORYSJ, T;
DR   P54423    , WPRA_BACSU , T; P42781    , XPR6_YARLI , T;
DR   P25036    , YSP3_YEAST , T;
DR   P85157    , ASE2_ACRSP , P; P80406    , CUDP_METCM , P;
DR   P83454    , NCP3_COPCM , P; P83433    , NVSP_ALIVI , P;
DR   P28308    , PRTE_HALME , P; Q10721    , SP01_SCEBO , P;
DR   P13858    , THEM_MALCI , P;
DR   P90794    , DCA11_CAEEL, F; Q9TUB3    , FOSB_CANLF , F;
DR   P53539    , FOSB_HUMAN , F; Q9BIW4    , LIMD_DICDI , F;
DR   P12021    , MUCAP_PIG  , F; Q0VSR5    , PAND_ALCBS , F;
DR   Q8MZS4    , PHYSA_PHYPO, F; P42790    , PICP_PSESR , F;
DR   Q70DX9    , SED1_ASPFU , F; D4ANG0    , SED2_ARTBC , F;
DR   C5FBW2    , SED2_ARTOC , F; Q70J59    , SED2_ASPFU , F;
DR   D4DBH6    , SED2_TRIVH , F; D4AK75    , SED3_ARTBC , F;
DR   C5FTQ5    , SED3_ARTOC , F; Q70GH4    , SED3_ASPFU , F;
DR   D4D7N6    , SED3_TRIVH , F; D4AIK6    , SED4_ARTBC , F;
DR   C5FRX4    , SED4_ARTOC , F; Q4WQU0    , SED4_ASPFU , F;
DR   D4D9U2    , SED4_TRIVH , F; Q4WGU1    , SED5_ASPFU , F;
DR   B4NBP4    , SPAST_DROWI, F; Q9HBL0    , TENS1_HUMAN, F;
DR   Q55CT0    , TPP1_DICDI , F; P98080    , UCR1_CAEEL , F;
DR   Q60106    , XANP_XANS2 , F; P0C8L8    , YL139_YARLI, F;
3D   1AF4; 1AH2; 1AK9; 1AQN; 1AU9; 1BE6; 1BE8; 1BFK; 1BFU; 1BH6; 1BJR; 1C3L;
3D   1C9J; 1CNM; 1CSE; 1DBI; 1DUI; 1EGQ; 1GCI; 1HT3; 1IC6; 1JEA; 1LW6; 1MEE;
3D   1MPT; 1NDQ; 1NDU; 1OT5; 1OYO; 1OYV; 1P7V; 1P7W; 1P8J; 1PEK; 1PFG; 1PJ8;
3D   1PTK; 1R0R; 1R64; 1R6V; 1S01; 1S02; 1SBC; 1SBH; 1SBI; 1SBN; 1SBT; 1SCA;
3D   1SCB; 1SCD; 1SCN; 1SIB; 1ST2; 1ST3; 1SUE; 1SUP; 1SVN; 1TEC; 1THM; 1TK2;
3D   1TM1; 1TM3; 1TM4; 1TM5; 1TM7; 1TMG; 1TO1; 1TO2; 1WSD; 1XF1; 1Y1K; 1Y33;
3D   1Y34; 1Y3B; 1Y3C; 1Y3D; 1Y3F; 1Y48; 1Y4A; 1Y4D; 1YJA; 1YJB; 1YJC; 1YU6;
3D   2DP4; 2DQK; 2DUJ; 2G4V; 2HD4; 2HPZ; 2ID4; 2ID8; 2PKC; 2PQ2; 2PRK; 2PWA;
3D   2PWB; 2PYZ; 2SBT; 2SEC; 2SIC; 2SNI; 2ST1; 2TEC; 2V8B; 2WUV; 2WUW; 3AJ8;
3D   3AJ9; 3BX1; 3D9Q; 3DDZ; 3DE0; 3DE1; 3DE2; 3DE3; 3DE4; 3DE5; 3DE6; 3DE7;
3D   3DVQ; 3DVR; 3DVS; 3DW1; 3DW3; 3DWE; 3DYB; 3EIF; 3F49; 3F7M; 3GT3; 3GT4;
3D   3I2Y; 3I30; 3I34; 3I37; 3I6S; 3I74; 3L1K; 3LXU; 3OSZ; 3PRK; 3PTL; 3Q40;
3D   3Q5G; 3QMP; 3SIC; 3TEC; 3UNX; 3VTA; 4B5L; 4C3U; 4C3V; 4CFY; 4CFZ; 4CG0;
3D   4DJ5; 4DZT; 4FON; 4OMC; 4OMD; 4RYD; 4WOB; 4WOC; 4YN3; 4Z2A; 4ZAR; 5AMX;
3D   5AQE; 5ARB; 5ARC; 5ARD; 5AVJ; 5AVK; 5B1D; 5B1E; 5CW1; 5GL8; 5I9S; 5JMO;
3D   5JXG; 5JXH; 5JXI; 5JXJ; 5K7S; 5KXU; 5KXV; 5MIM; 5MJL; 5SIC; 5UVL; 5WHW;
3D   5WJG; 5WJH; 5WRC; 6CL7; 6CL8; 6CL9; 6CLA; 6CLB; 6EQV; 6EQW; 6EQX; 6FJS;
3D   6HLB; 6HLD; 6HLE; 6HZA; 6HZB; 6HZC; 6HZD; 6KKF; 6MH6; 6N4U; 6PKJ; 6PKK;
3D   6PKL; 6PKM; 6PKN; 6PKO; 6PKP; 6PKQ; 6PKR; 6PKS; 6PKT; 6PU4; 6PU5; 6QF1;
3D   6QXV; 6RUG; 6RUH; 6RUK; 6RUN; 6RUW; 6RVE; 6RVG; 6RZP;
PR   PRU10082;
DO   PDOC00125;
//
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