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Database: PROSITE
Entry: PS00427
LinkDB: PS00427
Original site: PS00427 
ID   DISINTEGRIN_1; PATTERN.
AC   PS00427;
DT   01-NOV-1990 CREATED; 01-APR-2006 DATA UPDATE; 10-APR-2019 INFO UPDATE.
DE   Disintegrins signature.
PA   C-x(2)-[GS]-x-C-C-x(1,2)-[NQRSEKD]-C-x-[FMYLVI]-x(6)-C-[RKNQ].
NR   /RELEASE=2019_03,559634;
NR   /TOTAL=242(242); /POSITIVE=242(242); /UNKNOWN=0(0); /FALSE_POS=0(0);
NR   /FALSE_NEG=99; /PARTIAL=12;
CC   /TAXO-RANGE=??E??; /MAX-REPEAT=1;
CC   /SITE=1,disulfide; /SITE=5,disulfide; /SITE=6,disulfide;
CC   /SITE=9,disulfide; /SITE=13,disulfide;
CC   /VERSION=2;
DR   Q9R158    , AD26A_MOUSE, T; O75078    , ADA11_HUMAN, T;
DR   Q9R1V4    , ADA11_MOUSE, T; O43184    , ADA12_HUMAN, T;
DR   Q61824    , ADA12_MOUSE, T; Q9Y3Q7    , ADA18_HUMAN, T;
DR   Q95194    , ADA18_MACFA, T; P97776    , ADA18_RAT  , T;
DR   Q9H013    , ADA19_HUMAN, T; O35674    , ADA19_MOUSE, T;
DR   O43506    , ADA20_HUMAN, T; Q9UKJ8    , ADA21_HUMAN, T;
DR   Q9JI76    , ADA21_MOUSE, T; Q9P0K1    , ADA22_HUMAN, T;
DR   Q9R1V6    , ADA22_MOUSE, T; O42596    , ADA22_XENLA, T;
DR   Q9R160    , ADA24_MOUSE, T; Q9UKQ2    , ADA28_HUMAN, T;
DR   Q9XSL6    , ADA28_MACFA, T; Q9JLN6    , ADA28_MOUSE, T;
DR   Q9UKF5    , ADA29_HUMAN, T; Q811Q4    , ADA29_MOUSE, T;
DR   Q9UKF2    , ADA30_HUMAN, T; Q8TC27    , ADA32_HUMAN, T;
DR   Q9BZ11    , ADA33_HUMAN, T; Q923W9    , ADA33_MOUSE, T;
DR   P70505    , ADAM1_RAT  , T; O77780    , ADAM2_BOVIN, T;
DR   Q60411    , ADAM2_CAVPO, T; Q99965    , ADAM2_HUMAN, T;
DR   Q28478    , ADAM2_MACFA, T; Q60718    , ADAM2_MOUSE, T;
DR   Q28660    , ADAM2_RABIT, T; Q63202    , ADAM2_RAT  , T;
DR   Q60472    , ADAM5_CAVPO, T; Q28483    , ADAM5_MACFA, T;
DR   Q3TTE0    , ADAM5_MOUSE, T; Q5BK84    , ADAM5_RAT  , T;
DR   Q9H2U9    , ADAM7_HUMAN, T; Q28475    , ADAM7_MACFA, T;
DR   O35227    , ADAM7_MOUSE, T; Q63180    , ADAM7_RAT  , T;
DR   P78325    , ADAM8_HUMAN, T; Q05910    , ADAM8_MOUSE, T;
DR   Q13443    , ADAM9_HUMAN, T; Q61072    , ADAM9_MOUSE, T;
DR   Q60813    , ADM1A_MOUSE, T; P83253    , DID1A_MACLB, T;
DR   Q6T6T3    , DID1_BITGA , T; Q3BER2    , DID1_ECHOC , T;
DR   Q3BK13    , DID2A_MACLB, T; Q6T6T2    , DID2_BITGA , T;
DR   Q3BER3    , DID4A_ECHOC, T; P0C6A8    , DID4_MACLO , T;
DR   Q3BER4    , DID5A_ECHOC, T; P0C6A4    , DID5B_ECHOC, T;
DR   P0C6B0    , DID5B_MACLO, T; P83041    , DID5_CERCE , T;
DR   P82465    , DID6A_ECHCS, T; P0C6A6    , DID7A_VIPBB, T;
DR   P83043    , DID8A_CERCE, T; P81742    , DIDAA_ERIMA, T;
DR   Q805F7    , DIDA_AGKCO , T; Q805F5    , DIDA_AGKPI , T;
DR   C9E1S2    , DIDA_AGKPL , T; Q3BK16    , DIDA_CERVI , T;
DR   P0C6A3    , DIDBA_ECHML, T; Q3BK15    , DIDB_CERVI , T;
DR   P0C6B4    , DIDLA_ECHCA, T; P0C6B5    , DIDLB_ECHCA, T;
DR   P83658    , DIDS_ECHCA , T; M5BGY5    , DID_ATHCH  , T;
DR   M5BHN0    , DID_ATHNI  , T; M5BGS2    , DID_ATHSQ  , T;
DR   Q5EE07    , DID_ECHCA  , T; Q3BER1    , DIS_ECHOC  , T;
DR   P0C7X6    , VM212_CROHD, T; P0C7X7    , VM212_CROSS, T;
DR   P81630    , VM23A_ECHCA, T; P81631    , VM23B_ECHCA, T;
DR   P0DM97    , VM25A_BITAR, T; P0C6A9    , VM25A_MACLO, T;
DR   P82466    , VM26B_ECHCS, T; J3SBP9    , VM28_CROAD , T;
DR   P0C6A5    , VM2A6_VIPAA, T; Q805F6    , VM2AB_AGKCO, T;
DR   P34182    , VM2AE_CROAT, T; Q8AWX7    , VM2AG_GLOHA, T;
DR   P0C6B6    , VM2AL_TRIAB, T; P0C6E3    , VM2B1_AGKBI, T;
DR   Q6T271    , VM2BI_BITGA, T; P17495    , VM2B_TRIGA , T;
DR   Q9IAB0    , VM2CO_AGKCO, T; P23323    , VM2C_PROFL , T;
DR   Q4JCS1    , VM2D2_BITAR, T; Q4JCS0    , VM2D3_BITAR, T;
DR   Q1PBD1    , VM2DI_GLOHA, T; P17349    , VM2E1_PROEL, T;
DR   Q90YA6    , VM2E2_PROEL, T; P17347    , VM2EA_ECHCS, T;
DR   Q7LZK1    , VM2EB_ECHPL, T; Q7LZK0    , VM2EG_ECHPL, T;
DR   P18619    , VM2FL_PROFL, T; P62384    , VM2G_TRIAB , T;
DR   P62383    , VM2G_TRIGA , T; U5PZ28    , VM2H1_BOTLA, T;
DR   Q90220    , VM2H1_GLOHA, T; Q90221    , VM2H2_GLOHA, T;
DR   P14530    , VM2HA_PROFL, T; Q90WC0    , VM2HS_GLOBR, T;
DR   Q7LZI5    , VM2I1_GLOUS, T; Q7LZT4    , VM2I2_GLOUS, T;
DR   Q5XUW8    , VM2IA_BOTIN, T; A2CJE5    , VM2IA_CROAT, T;
DR   P68520    , VM2IC_CROAT, T; A2CJE6    , VM2IV_CROVV, T;
DR   P31981    , VM2I_CROBA , T; P31982    , VM2I_CROCC , T;
DR   P31985    , VM2I_CROCE , T; P68521    , VM2I_CRODD , T;
DR   P31984    , VM2I_CROMM , T; P31986    , VM2I_CROOL , T;
DR   P31987    , VM2I_CROVV , T; P31990    , VM2I_LACMU , T;
DR   P22827    , VM2I_SISMB , T; P22828    , VM2I_SISTE , T;
DR   Q98SP2    , VM2J2_BOTJA, T; Q0NZX5    , VM2JA_BOTJA, T;
DR   P31989    , VM2JC_BOTJA, T; P0C6E4    , VM2JN_PROJR, T;
DR   Q0NZX6    , VM2JR_BOTJA, T; P83912    , VM2JT_PROJR, T;
DR   Q7ZZS9    , VM2J_PROJR , T; Q98995    , VM2L2_MACLB, T;
DR   Q698K8    , VM2L4_GLOBR, T; P0C7A7    , VM2LA_ECHLE, T;
DR   P0C7A8    , VM2LB_ECHLE, T; O73795    , VM2MB_GLOBR, T;
DR   Q9YI19    , VM2MC_GLOBR, T; Q9PVK9    , VM2MD_GLOBR, T;
DR   P0C6R5    , VM2MU_ECHML, T; Q14FJ4    , VM2OC_ECHOC, T;
DR   P0C6R6    , VM2OI_ECHOC, T; E9NW26    , VM2P1_PROMU, T;
DR   E9NW27    , VM2P2_PROMU, T; P0C6R7    , VM2PA_ECHPL, T;
DR   P0C6R8    , VM2PB_ECHPL, T; P30403    , VM2RH_CALRH, T;
DR   O93516    , VM2S2_GLOBR, T; O93515    , VM2S3_GLOBR, T;
DR   Q7SZE0    , VM2SA_GLOSA, T; O57413    , VM2T3_PROMU, T;
DR   P15503    , VM2TA_TRIGA, T; P22826    , VM2TI_ERIMA, T;
DR   P0C6S4    , VM2TO_ERIMA, T; P21859    , VM2T_PROFL , T;
DR   Q7SZD9    , VM2US_GLOUS, T; C9E1R7    , VM2V2_CROAT, T;
DR   C9E1R9    , VM2V2_CROVV, T; P16338    , VM2_AGKPI  , T;
DR   P17497    , VM2_BITAR  , T; Q801Z4    , VM2_BOTAL  , T;
DR   Q072L5    , VM2_BOTAS  , T; P18618    , VM2_BOTAT  , T;
DR   P31988    , VM2_BOTCO  , T; J9Z332    , VM2_CROAD  , T;
DR   H9M5U4    , VM2_CRORU  , T; C0HJM4    , VM2_CROSM  , T;
DR   C0HK50    , VM2_CROTA  , T; P21858    , VM2_GLOBL  , T;
DR   Q9DGH6    , VM2_GLOHA  , T; P0DM87    , VM2_TRIST  , T;
DR   C5H5D2    , VM31_BOTAT , T; C5H5D1    , VM31_CRODC , T;
DR   Q076D1    , VM31_CRODU , T; C5H5D5    , VM31_LACMR , T;
DR   J3S829    , VM32A_CROAD, T; P0DM89    , VM32A_GLOBR, T;
DR   P0DM90    , VM32B_GLOBR, T; J3SDW6    , VM32D_CROAD, T;
DR   C5H5D3    , VM32_BOTAT , T; C5H5D6    , VM32_LACMR , T;
DR   C5H5D4    , VM33_BOTAT , T; J3S830    , VM33_CROAD , T;
DR   F8S108    , VM34_CROAD , T; F8RKW1    , VM34_DRYCN , T;
DR   Q8QG88    , VM36A_BOTIN, T; J3SDW8    , VM38_CROAD , T;
DR   F8RKW0    , VM38_DRYCN , T; F8RKV9    , VM39_DRYCN , T;
DR   Q92043    , VM3AA_CROAT, T; O42138    , VM3AD_AGKCL, T;
DR   Q9W6M5    , VM3AH_DEIAC, T; Q1PS45    , VM3AK_DEIAC, T;
DR   Q0NZY0    , VM3B1_BOTJA, T; Q1PHZ4    , VM3B1_BOTJR, T;
DR   Q0NZX9    , VM3B2_BOTJA, T; Q0NZX8    , VM3B3_BOTJA, T;
DR   Q0NZX7    , VM3B4_BOTJA, T; Q8UVG0    , VM3BE_BOTER, T;
DR   O93523    , VM3BP_BOTJA, T; Q7LZ61    , VM3CX_DABSI, T;
DR   Q7T046    , VM3CX_MACLB, T; A2CJE4    , VM3C_CROAT , T;
DR   B8K1W0    , VM3DK_DABRR, T; Q2UXR0    , VM3E1_ECHOC, T;
DR   Q2UXQ5    , VM3E2_ECHOC, T; Q6X1T6    , VM3E6_ECHOC, T;
DR   Q90495    , VM3E_ECHCA , T; P0C6E8    , VM3G1_TRIGA, T;
DR   Q9PSN7    , VM3H1_CRORU, T; Q90ZI3    , VM3H1_PROFL, T;
DR   Q98UF9    , VM3H3_BOTJA, T; P0C7B0    , VM3H6_GLOBR, T;
DR   Q8AWI5    , VM3HA_GLOHA, T; Q8JIR2    , VM3HA_PROFL, T;
DR   P20164    , VM3HB_PROFL, T; Q90Y44    , VM3H_GLOHA , T;
DR   P30431    , VM3JA_BOTJA, T; P86092    , VM3LB_BOTLC, T;
DR   C0LZJ5    , VM3LC_MACLN, T; P0DJ87    , VM3L_BOTLC , T;
DR   Q10749    , VM3M1_NAJMO, T; O93517    , VM3S4_GLOBR, T;
DR   O93518    , VM3S5_GLOBR, T; Q3HTN1    , VM3SA_TRIST, T;
DR   Q3HTN2    , VM3SB_TRIST, T; A2CJE2    , VM3S_CROSS , T;
DR   Q2LD49    , VM3TM_TRIST, T; Q9DGB9    , VM3V1_CROAT, T;
DR   C9E1S0    , VM3V3_AGKPL, T; C9E1R8    , VM3V3_CROVV, T;
DR   A4PBQ9    , VM3VA_CROAT, T; Q4VM08    , VM3VA_MACLB, T;
DR   Q90282    , VM3VB_CROAT, T; Q4VM07    , VM3VB_MACLB, T;
DR   A2CJE3    , VM3V_CROVV , T; A8QL48    , VM3_BUNFA  , T;
DR   A8QL49    , VM3_BUNMU  , T; Q2QA02    , VM3_CRODD  , T;
DR   A8QL59    , VM3_NAJAT  , T; A3R0T9    , VM3_OPHHA  , T;
DR   P0DMH4    , VM2_BOTFO  , P; P0DJH2    , VM3AL_TRIAB, P;
DR   P0DJE2    , VM3A_VIPAA , P; P22028    , VM3B_BOTJA , P;
DR   P0C7N3    , VM3CR_CROVV, P; P85005    , VM3PN_PROSR, P;
DR   P0DKR0    , VM3_BOTMO  , P; P0DJJ4    , VM3_NAJOX  , P;
DR   P0DM88    , VM3_PROJR  , P; P0DJ44    , VM3_VIPAA  , P;
DR   P0DJH3    , VMP3A_DEIAC, P; P85006    , VMXP_PROSR , P;
DR   Q10741    , ADA10_BOVIN, N; G5EFD9    , ADA10_CAEEL, N;
DR   O14672    , ADA10_HUMAN, N; O35598    , ADA10_MOUSE, N;
DR   O77633    , ADA10_PIG  , N; Q10743    , ADA10_RAT  , N;
DR   Q8JIY1    , ADA10_XENLA, N; Q9PSZ3    , ADA11_XENLA, N;
DR   Q13444    , ADA15_HUMAN, N; O88839    , ADA15_MOUSE, N;
DR   Q9QYV0    , ADA15_RAT  , N; Q94316    , ADA17_CAEEL, N;
DR   Q9VAC5    , ADA17_DROME, N; P78536    , ADA17_HUMAN, N;
DR   Q9Z0F8    , ADA17_MOUSE, N; Q9Z1K9    , ADA17_RAT  , N;
DR   Q9R157    , ADA18_MOUSE, N; O75077    , ADA23_HUMAN, N;
DR   Q9R1V7    , ADA23_MOUSE, N; Q9R159    , ADA25_MOUSE, N;
DR   Q8K410    , ADA32_MOUSE, N; Q6NVV9    , ADAM5_HUMAN, N;
DR   O15204    , ADEC1_HUMAN, N; Q9R0X2    , ADEC1_MOUSE, N;
DR   Q8R534    , ADM1B_MOUSE, N; D4B1G0    , ADMB_ARTBC , N;
DR   C5FUK3    , ADMB_ARTOC , N; Q4WQ08    , ADMB_ASPFU , N;
DR   D4DCV9    , ADMB_TRIVH , N; G5ECS8    , ADT1_CAEEL , N;
DR   Q19204    , ADT2_CAEEL , N; Q9H324    , ATS10_HUMAN, N;
DR   P58459    , ATS10_MOUSE, N; P58397    , ATS12_HUMAN, N;
DR   Q811B3    , ATS12_MOUSE, N; Q76LX8    , ATS13_HUMAN, N;
DR   Q769J6    , ATS13_MOUSE, N; Q8WXS8    , ATS14_HUMAN, N;
DR   Q8TE58    , ATS15_HUMAN, N; P59384    , ATS15_MOUSE, N;
DR   Q8TE57    , ATS16_HUMAN, N; Q69Z28    , ATS16_MOUSE, N;
DR   Q8TE56    , ATS17_HUMAN, N; Q8TE60    , ATS18_HUMAN, N;
DR   Q4VC17    , ATS18_MOUSE, N; Q8TE59    , ATS19_HUMAN, N;
DR   P59509    , ATS19_MOUSE, N; Q9UHI8    , ATS1_HUMAN , N;
DR   P97857    , ATS1_MOUSE , N; Q9WUQ1    , ATS1_RAT   , N;
DR   P59510    , ATS20_HUMAN, N; P59511    , ATS20_MOUSE, N;
DR   P79331    , ATS2_BOVIN , N; O95450    , ATS2_HUMAN , N;
DR   Q8C9W3    , ATS2_MOUSE , N; O15072    , ATS3_HUMAN , N;
DR   Q9TT93    , ATS4_BOVIN , N; O75173    , ATS4_HUMAN , N;
DR   Q8BNJ2    , ATS4_MOUSE , N; Q5RFQ8    , ATS4_PONAB , N;
DR   Q9ESP7    , ATS4_RAT   , N; Q9TT92    , ATS5_BOVIN , N;
DR   Q9UNA0    , ATS5_HUMAN , N; Q9R001    , ATS5_MOUSE , N;
DR   Q9UKP5    , ATS6_HUMAN , N; Q9UKP4    , ATS7_HUMAN , N;
DR   Q68SA9    , ATS7_MOUSE , N; Q1EHB3    , ATS7_RAT   , N;
DR   Q9UP79    , ATS8_HUMAN , N; P57110    , ATS8_MOUSE , N;
DR   Q9P2N4    , ATS9_HUMAN , N; P83254    , DID1B_MACLB, N;
DR   P83044    , DID8B_CERCE, N; Q3BK17    , DIS_CERVI  , N;
DR   P0C6E2    , DIS_DABPA  , N; Q3BK14    , DIS_MACLB  , N;
DR   P83469    , DIS_MACLO  , N; Q7ZZM2    , DIS_PROJR  , N;
DR   Q19791    , GON1_CAEEL , N; O13766    , MDE10_SCHPO, N;
DR   Q20930    , MIG17_CAEEL, N; G5EFD5    , UNC71_CAEEL, N;
DR   P0C6A7    , VM27B_VIPBB, N; Q9PWJ0    , VM2A2_DEIAC, N;
DR   P81743    , VM2AB_ERIMA, N; Q9IAX6    , VM2M2_DEIAC, N;
DR   Q805F4    , VM2PB_AGKPI, N; C9E1S1    , VM2V2_AGKPL, N;
DR   C0HJM5    , VM2_CERSA  , N; P0DM77    , VM2_DEIAC  , N;
DR   P0C6R9    , VM3A_BOTAL , N; D5LMJ3    , VM3A_NAJAT , N;
DR   D6PXE8    , VM3B_NAJAT , N; D3TTC2    , VM3H_NAJAT , N;
DR   D3TTC1    , VM3KL_NAJAT, N; P82942    , VM3K_NAJKA , N;
DR   D8VNS0    , VM3_CERRY  , N; P0DJ43    , VM3_MICIK  , N;
DR   Q9PVK7    , VM3_NAJKA  , N;
3D   1FVL; 1J2L; 1L3X; 1N4Y; 1Q7I; 1Q7J; 1RMR; 1RO3; 1TEJ; 1Z1X; 2DW0; 2DW1;
3D   2DW2; 2E3X; 2ECH; 2ERO; 2ERP; 2ERQ; 2LJV; 2M75; 2M7F; 2M7H; 2MOP; 2MP5;
3D   2PJF; 2PJG; 2PJI; 3C05; 3DSL; 3G5C; 3UCI; 4M4C; 4R5R; 4RQG; 5Y2Z; 5Y31;
DO   PDOC00351;
//
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