GenomeNet

Database: PROSITE
Entry: PS50020
LinkDB: PS50020
Original site: PS50020 
ID   WW_DOMAIN_2; MATRIX.
AC   PS50020;
DT   01-NOV-1995 CREATED; 10-MAY-2017 DATA UPDATE; 13-FEB-2019 INFO UPDATE.
DE   WW/rsp5/WWP domain profile.
MA   /GENERAL_SPEC: ALPHABET='ABCDEFGHIKLMNPQRSTVWYZ'; LENGTH=34;
MA   /DISJOINT: DEFINITION=PROTECT; N1=4; N2=31;
MA   /NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=0.2776000; R2=0.0197000; TEXT='NScore';
MA   /NORMALIZATION: MODE=-1; FUNCTION=LINEAR; R1=1518.2681885; R2=1.0788643; PRIORITY=1; TEXT='Heuristic 5.0%';
MA   /CUT_OFF: LEVEL=0; SCORE=418; H_SCORE=1969; N_SCORE=8.5; MODE=1; TEXT='!';
MA   /CUT_OFF: LEVEL=-1; SCORE=316; H_SCORE=1859; N_SCORE=6.5; MODE=1; TEXT='?';
MA   /DEFAULT: D=-20; I=-20; B1=-50; E1=-50; MI=-105; MD=-105; IM=-105; DM=-105;
MA   /I: B1=0; BI=-105; BD=-105;
MA   /M: SY='S'; M=-5,-9,-25,-10,-3,-21,-5,-13,-15,-7,-16,-9,-6,-1,0,-5,2,1,-13,-26,-17,-3;
MA   /M: SY='P'; M=-7,-5,-30,-1,-1,-24,-5,-13,-22,-9,-24,-17,-4,27,-6,-13,0,-5,-24,-29,-22,-5;
MA   /M: SY='L'; M=-8,-23,-19,-24,-18,2,-27,-18,15,-22,29,12,-22,-24,-16,-14,-21,-7,12,-24,-5,-18;
MA   /M: SY='P'; M=-9,-10,-34,-5,7,-27,-18,-12,-18,-6,-23,-13,-10,49,1,-13,-5,-8,-26,-29,-23,1;
MA   /M: SY='P'; M=-1,-1,-24,1,-2,-22,-6,-11,-21,-5,-24,-17,2,12,-5,-10,8,1,-19,-29,-17,-5;
MA   /M: SY='G'; M=-4,-9,-31,-7,-11,-29,34,-14,-30,-16,-27,-18,-3,4,-12,-18,-1,-14,-27,-24,-25,-13;
MA   /M: SY='W'; M=-20,-40,-50,-40,-30,10,-20,-30,-20,-20,-20,-20,-40,-30,-20,-20,-40,-30,-30,150,30,-20;
MA   /M: SY='E'; M=-8,0,-25,3,24,-20,-20,-7,-21,15,-18,-10,-3,-8,9,5,-2,-3,-16,-25,-12,16;
MA   /M: SY='E'; M=-1,-8,-15,-8,7,-19,-15,-11,-13,1,-11,-5,-9,-15,1,1,-3,-5,-6,-26,-15,3;
MA   /M: SY='R'; M=-2,-16,-23,-18,-12,-7,-20,-4,-7,-1,-7,-3,-12,-21,-7,6,-9,-8,-2,-10,2,-11;
MA   /M: SY='Y'; M=-11,-14,-24,-18,-8,4,-25,-10,-5,-4,-4,1,-12,-19,-4,-5,-10,-2,-5,-7,5,-6;
MA   /M: SY='D'; M=-5,17,-20,19,3,-23,-11,1,-22,-6,-20,-14,10,-12,-2,-9,10,10,-15,-34,-13,0;
MA   /M: SY='B'; M=-2,6,-25,6,3,-26,-6,-8,-23,-1,-23,-16,4,3,-3,-8,3,0,-19,-29,-18,-1;
MA   /M: SY='N'; M=-7,10,-22,10,8,-21,-13,-6,-22,6,-22,-15,11,-13,1,2,7,2,-16,-31,-15,5;
MA   /I: MD=-27;
MA   /M: SY='G'; M=-3,-5,-26,-7,-11,-23,30,-13,-28,-3,-23,-12,2,-17,-10,-7,-2,-11,-22,-18,-17,-11; D=-5;
MA   /I: I=-10; MI=-5; MD=-27; IM=-5; DM=-27;
MA   /M: SY='R'; M=-13,-10,-25,-12,-3,-14,-17,-7,-18,14,-14,-7,-4,-18,3,34,-7,-4,-11,-20,-8,-3; D=-5;
MA   /I: DM=-27;
MA   /M: SY='P'; M=-7,-15,-25,-16,-9,-8,-23,-17,-5,-7,-11,-7,-13,5,-11,-9,-5,3,-4,-14,-5,-12;
MA   /M: SY='Y'; M=-19,-24,-26,-27,-24,40,-30,5,4,-17,4,1,-20,-30,-19,-14,-20,-10,-3,20,59,-24;
MA   /M: SY='Y'; M=-20,-24,-26,-28,-24,50,-30,4,0,-18,4,0,-20,-30,-22,-14,-20,-10,-6,22,60,-24;
MA   /M: SY='Y'; M=-12,-26,-25,-29,-24,10,-29,-9,13,-21,7,5,-22,-26,-19,-18,-18,-8,10,6,14,-23;
MA   /M: SY='N'; M=-12,40,-22,29,4,-24,-3,12,-24,0,-30,-21,51,-18,0,-2,7,-3,-30,-40,-18,2;
MA   /M: SY='H'; M=-12,-5,-28,-5,-3,-18,-20,39,-19,-8,-12,-3,-1,-5,0,-4,-9,-10,-19,-28,2,-5;
MA   /M: SY='E'; M=-5,2,-23,0,9,-19,-17,-8,-12,2,-13,-9,5,-10,2,-3,-1,-3,-11,-29,-15,5;
MA   /M: SY='T'; M=-1,3,-13,-5,-8,-12,-17,-16,-10,-10,-11,-11,5,-12,-8,-11,17,34,-3,-32,-12,-8;
MA   /M: SY='K'; M=-11,1,-29,-1,4,-28,-7,1,-29,25,-27,-10,6,-14,11,22,-6,-11,-24,-22,-12,7;
MA   /M: SY='E'; M=-7,5,-23,5,17,-23,-19,-4,-23,10,-20,-13,2,-8,7,5,5,10,-17,-28,-12,12;
MA   /M: SY='T'; M=3,0,-10,-7,-7,-13,-14,-17,-13,-10,-16,-13,3,-10,-7,-10,26,40,-3,-33,-13,-7;
MA   /M: SY='Q'; M=-6,-5,-11,-8,0,-19,-19,-5,-16,-3,-14,-7,-3,-15,14,1,7,11,-14,-25,-7,6;
MA   /M: SY='W'; M=-19,-36,-45,-37,-28,14,-21,-24,-17,-19,-16,-17,-35,-29,-20,-19,-34,-24,-25,124,33,-20;
MA   /M: SY='E'; M=-9,4,-25,9,19,-22,-20,-6,-15,0,-14,-11,-2,-10,8,-5,0,-2,-14,-27,-10,13;
MA   /M: SY='D'; M=-15,5,-32,12,8,-29,-18,4,-27,10,-25,-15,1,11,2,8,-8,-11,-24,-29,-14,2;
MA   /M: SY='P'; M=-10,-20,-40,-10,0,-30,-20,-20,-20,-10,-30,-20,-20,90,-10,-20,-10,-10,-30,-30,-30,-10;
MA   /M: SY='R'; M=-9,1,-23,0,1,-20,-14,-8,-21,10,-16,-11,2,-16,0,19,-1,0,-13,-27,-13,-1;
MA   /M: SY='M'; M=-10,-15,-24,-17,-8,-2,-13,-10,-6,-11,-1,2,-12,-11,-11,-8,-11,-6,-6,-20,-6,-10;
MA   /I: E1=0; IE=-105; DE=-105;
NR   /RELEASE=2019_02,559228;
NR   /TOTAL=379(220); /POSITIVE=379(220); /UNKNOWN=0(0); /FALSE_POS=0(0);
NR   /FALSE_NEG=13; /PARTIAL=0;
CC   /MATRIX_TYPE=protein_domain;
CC   /SCALING_DB=reversed;
CC   /AUTHOR=K_Hofmann;
CC   /TAXO-RANGE=??E??; /MAX-REPEAT=4;
CC   /FT_KEY=DOMAIN; /FT_DESC=WW;
CC   /VERSION=5;
DR   O00213    , APBB1_HUMAN, T; Q9QXJ1    , APBB1_MOUSE, T;
DR   P46933    , APBB1_RAT  , T; Q92870    , APBB2_HUMAN, T;
DR   Q9DBR4    , APBB2_MOUSE, T; O95704    , APBB3_HUMAN, T;
DR   Q8R1C9    , APBB3_MOUSE, T; O35827    , APBB3_RAT  , T;
DR   O95817    , BAG3_HUMAN , T; Q9JLV1    , BAG3_MOUSE , T;
DR   Q9VYD1    , C1716_DROME, T; A0A0R4IKJ1, CAPAM_DANRE, T;
DR   Q9H4Z3    , CAPAM_HUMAN, T; P59114    , CAPAM_MOUSE, T;
DR   Q9UPV0    , CE164_HUMAN, T; Q5DU05    , CE164_MOUSE, T;
DR   A2VE39    , CMTR1_BOVIN, T; Q803R5    , CMTR1_DANRE, T;
DR   Q9DBC3    , CMTR1_MOUSE, T; Q6GQ76    , CMTR1_XENLA, T;
DR   P46942    , DB10_NICSY , T; A6QR44    , DGCR8_BOVIN, T;
DR   Q8WYQ5    , DGCR8_HUMAN, T; Q9EQM6    , DGCR8_MOUSE, T;
DR   Q9VDW6    , DMDA_DROME , T; Q9VDW3    , DMDB_DROME , T;
DR   Q0KI50    , DMDD_DROME , T; Q7YU29    , DMDE_DROME , T;
DR   Q9TW65    , DMD_CAEEL  , T; O97592    , DMD_CANLF  , T;
DR   P11533    , DMD_CHICK  , T; P11532    , DMD_HUMAN  , T;
DR   P11531    , DMD_MOUSE  , T; Q5GN48    , DMD_PIG    , T;
DR   P11530    , DMD_RAT    , T; P54353    , DOD_DROME  , T;
DR   Q09685    , DRE4_SCHPO , T; Q13474    , DRP2_HUMAN , T;
DR   Q05AA6    , DRP2_MOUSE , T; Q9EPA0    , DRP2_RAT   , T;
DR   Q54T86    , DWWA_DICDI , T; P22696    , ESS1_YEAST , T;
DR   O04425    , FCA_ARATH  , T; Q9BKZ9    , FEH1_CAEEL , T;
DR   Q8N3X1    , FNBP4_HUMAN, T; Q6ZQ03    , FNBP4_MOUSE, T;
DR   Q14CM0    , FRPD4_HUMAN, T; A2AFR3    , FRPD4_MOUSE, T;
DR   O60861    , GAS7_HUMAN , T; Q60780    , GAS7_MOUSE , T;
DR   O55148    , GAS7_RAT   , T; Q09291    , HECW1_CAEEL, T;
DR   Q76N89    , HECW1_HUMAN, T; Q8K4P8    , HECW1_MOUSE, T;
DR   Q9P2P5    , HECW2_HUMAN, T; Q6I6G8    , HECW2_MOUSE, T;
DR   P46940    , IQGA1_HUMAN, T; Q13576    , IQGA2_HUMAN, T;
DR   Q3UQ44    , IQGA2_MOUSE, T; Q96J02    , ITCH_HUMAN , T;
DR   Q8C863    , ITCH_MOUSE , T; B3LWS4    , KIBRA_DROAN, T;
DR   B3P3M8    , KIBRA_DROER, T; Q9VFG8    , KIBRA_DROME, T;
DR   B4K6I9    , KIBRA_DROMO, T; B4HEJ6    , KIBRA_DROSE, T;
DR   B4M5X4    , KIBRA_DROVI, T; B4NAD3    , KIBRA_DROWI, T;
DR   B4PSQ2    , KIBRA_DROYA, T; Q8IX03    , KIBRA_HUMAN, T;
DR   Q5SXA9    , KIBRA_MOUSE, T; A4IIJ3    , KIBRA_XENTR, T;
DR   Q96QZ7    , MAGI1_HUMAN, T; Q6RHR9    , MAGI1_MOUSE, T;
DR   Q4L1J4    , MAGI1_RAT  , T; Q86UL8    , MAGI2_HUMAN, T;
DR   Q9WVQ1    , MAGI2_MOUSE, T; O88382    , MAGI2_RAT  , T;
DR   Q5F488    , MAGI3_CHICK, T; Q5TCQ9    , MAGI3_HUMAN, T;
DR   Q9EQJ9    , MAGI3_MOUSE, T; Q9JK71    , MAGI3_RAT  , T;
DR   A1A5G4    , MAGI3_XENTR, T; Q867T7    , NCFA_DICDI , T;
DR   Q96PU5    , NED4L_HUMAN, T; Q8CFI0    , NED4L_MOUSE, T;
DR   Q5RBF2    , NED4L_PONAB, T; Q9VVI3    , NEDD4_DROME, T;
DR   P46934    , NEDD4_HUMAN, T; P46935    , NEDD4_MOUSE, T;
DR   Q62940    , NEDD4_RAT  , T; Q5BIN5    , PIN1_BOVIN , T;
DR   Q13526    , PIN1_HUMAN , T; Q4R383    , PIN1_MACFA , T;
DR   Q9QUR7    , PIN1_MOUSE , T; P0C1J8    , PIN1_RHIO9 , T;
DR   O74448    , PIN1_SCHPO , T; O15428    , PINL_HUMAN , T;
DR   Q9HAU0    , PKHA5_HUMAN, T; B6RSP1    , PKHA7_DANRE, T;
DR   Q6IQ23    , PKHA7_HUMAN, T; Q3UIL6    , PKHA7_MOUSE, T;
DR   Q2HJC9    , PQBP1_BOVIN, T; A1YFA7    , PQBP1_GORGO, T;
DR   O60828    , PQBP1_HUMAN, T; Q91VJ5    , PQBP1_MOUSE, T;
DR   A2T806    , PQBP1_PONPY, T; Q6PCT5    , PQBP1_RAT  , T;
DR   F4JCC1    , PR35B_ARATH, T; B6EUA9    , PR40A_ARATH, T;
DR   O75400    , PR40A_HUMAN, T; Q9R1C7    , PR40A_MOUSE, T;
DR   Q6NWY9    , PR40B_HUMAN, T; Q80W14    , PR40B_MOUSE, T;
DR   Q9LT25    , PR40C_ARATH, T; O14176    , PRP40_SCHPO, T;
DR   P33203    , PRP40_YEAST, T; Q92462    , PUB1_SCHPO , T;
DR   Q9UTG2    , PUB2_SCHPO , T; O14326    , PUB3_SCHPO , T;
DR   Q8H136    , RH14_ARATH , T; Q5VQL1    , RH14_ORYSJ , T;
DR   Q9SQV1    , RH40_ARATH , T; Q5JKF2    , RH40_ORYSJ , T;
DR   Q9LYJ9    , RH46_ARATH , T; Q9BRR9    , RHG09_HUMAN, T;
DR   Q8IWW6    , RHG12_HUMAN, T; Q9BE31    , RHG12_MACFA, T;
DR   Q8C0D4    , RHG12_MOUSE, T; Q6ZUM4    , RHG27_HUMAN, T;
DR   A2AB59    , RHG27_MOUSE, T; Q6TLK4    , RHG27_RAT  , T;
DR   Q9C0H5    , RHG39_HUMAN, T; P59281    , RHG39_MOUSE, T;
DR   A1CQG2    , RSP5_ASPCL , T; B0XQ72    , RSP5_ASPFC , T;
DR   B8N7E5    , RSP5_ASPFN , T; Q4WTF3    , RSP5_ASPFU , T;
DR   A2QQ28    , RSP5_ASPNC , T; Q2UBP1    , RSP5_ASPOR , T;
DR   Q0CCL1    , RSP5_ASPTN , T; G0S9J5    , RSP5_CHATD , T;
DR   Q5BDP1    , RSP5_EMENI , T; A1D3C5    , RSP5_NEOFI , T;
DR   P39940    , RSP5_YEAST , T; Q7XZU0    , SAC9_ARATH , T;
DR   Q9H4B6    , SAV1_HUMAN , T; Q8VEB2    , SAV1_MOUSE , T;
DR   A4V8B4    , SAV1_RAT   , T; Q9VCR6    , SAV_DROME  , T;
DR   P0CR41    , SEC24_CRYNB, T; P0CR40    , SEC24_CRYNJ, T;
DR   Q4P9K4    , SEC24_USTMA, T; Q2UTN6    , SET2_ASPOR , T;
DR   Q59XV0    , SET2_CANAL , T; Q6FX50    , SET2_CANGA , T;
DR   Q2H988    , SET2_CHAGB , T; Q1DU03    , SET2_COCIM , T;
DR   Q6BM04    , SET2_DEBHA , T; Q5ASA5    , SET2_EMENI , T;
DR   Q4IB50    , SET2_GIBZE , T; Q7RZU4    , SET2_NEUCR , T;
DR   Q6C5G5    , SET2_YARLI , T; Q9BYW2    , SETD2_HUMAN, T;
DR   E9Q5F9    , SETD2_MOUSE, T; Q9V853    , SMUF1_DROME, T;
DR   Q9HCE7    , SMUF1_HUMAN, T; Q9CUN6    , SMUF1_MOUSE, T;
DR   Q9PUN2    , SMUF1_XENLA, T; A9JRZ0    , SMUF2_DANRE, T;
DR   Q9HAU4    , SMUF2_HUMAN, T; A2A5Z6    , SMUF2_MOUSE, T;
DR   Q2TAS2    , SMUF2_XENLA, T; O60045    , SSP1_NEUCR , T;
DR   Q6ZWJ1    , STXB4_HUMAN, T; Q9WV89    , STXB4_MOUSE, T;
DR   Q9Y0H4    , SUDX_DROME , T; O14776    , TCRG1_HUMAN, T;
DR   Q8CGF7    , TCRG1_MOUSE, T; Q5VWI1    , TCRGL_HUMAN, T;
DR   Q3B807    , TCRGL_MOUSE, T; P46941    , TG325_CAEEL, T;
DR   Q06525    , URN1_YEAST , T; P46939    , UTRO_HUMAN , T;
DR   Q7ZUK7    , WAC_DANRE  , T; Q9VX88    , WAC_DROME  , T;
DR   Q9BTA9    , WAC_HUMAN  , T; Q924H7    , WAC_MOUSE  , T;
DR   Q5U4Q0    , WAC_XENTR  , T; Q5F457    , WBP4_CHICK , T;
DR   O75554    , WBP4_HUMAN , T; Q61048    , WBP4_MOUSE , T;
DR   Q5HZF2    , WBP4_RAT   , T; Q6AWC2    , WWC2_HUMAN , T;
DR   Q6NXJ0    , WWC2_MOUSE , T; Q6DJR2    , WWC2_XENTR , T;
DR   P43582    , WWM1_YEAST , T; Q5F389    , WWOX_CHICK , T;
DR   Q803A8    , WWOX_DANRE , T; Q9VLU5    , WWOX_DROME , T;
DR   Q9NZC7    , WWOX_HUMAN , T; Q91WL8    , WWOX_MOUSE , T;
DR   Q5R9W5    , WWOX_PONAB , T; Q9H0M0    , WWP1_HUMAN , T;
DR   Q8BZZ3    , WWP1_MOUSE , T; O00308    , WWP2_HUMAN , T;
DR   Q9DBH0    , WWP2_MOUSE , T; Q9GZV5    , WWTR1_HUMAN, T;
DR   Q9EPK5    , WWTR1_MOUSE, T; D6C652    , YAP1A_XENLA, T;
DR   Q19404    , YAP1_CAEEL , T; P46936    , YAP1_CHICK , T;
DR   Q1L8J7    , YAP1_DANRE , T; Q45VV3    , YAP1_DROME , T;
DR   P46937    , YAP1_HUMAN , T; P46938    , YAP1_MOUSE , T;
DR   H2LBU8    , YAP1_ORYLA , T; Q2EJA0    , YAP1_RAT   , T;
DR   P34600    , YO61_CAEEL , T; Q8GSP8    , ZYS3_CHLRE , T;
DR   D2HRF1    , CMTR1_AILME, N; Q8N1G2    , CMTR1_HUMAN, N;
DR   Q5R981    , CMTR1_PONAB, N; Q5U2Z5    , CMTR1_RAT  , N;
DR   Q9JKF1    , IQGA1_MOUSE, N; Q757Y8    , SET2_ASHGO , N;
DR   Q4WTT2    , SET2_ASPFU , N; Q6CXP5    , SET2_KLULA , N;
DR   P46995    , SET2_YEAST , N; O14097    , YERE_SCHPO , N;
DR   O94425    , YHK5_SCHPO , N; O94426    , YHK6_SCHPO , N;
DR   O13598    , YNI8_SCHPO , N;
3D   1E0L; 1EG3; 1EG4; 1F8A; 1I5H; 1I6C; 1I8G; 1I8H; 1JMQ; 1K5R; 1K9Q; 1K9R;
3D   1NMV; 1O6W; 1PIN; 1TK7; 1WMV; 1WR3; 1WR4; 1WR7; 1YIU; 1YWI; 1YWJ; 1ZCN;
3D   1ZR7; 2DJY; 2DK1; 2DK7; 2DMV; 2DWV; 2DYF; 2E45; 2EZ5; 2F21; 2HO2; 2IDH;
3D   2ITK; 2JMF; 2JO9; 2JOC; 2JUP; 2JX8; 2JXW; 2KBU; 2KCF; 2KPZ; 2KQ0; 2KXQ;
3D   2KYK; 2L5F; 2LAJ; 2LAW; 2LAX; 2LAY; 2LAZ; 2LB0; 2LB1; 2LB2; 2LB3; 2LTV;
3D   2LTW; 2LTX; 2LTY; 2LTZ; 2M3O; 2M8I; 2M8J; 2M9E; 2M9F; 2M9I; 2M9J; 2MDC;
3D   2MDI; 2MDJ; 2MPT; 2MW9; 2MWA; 2MWB; 2MWD; 2MWE; 2MWF; 2N1O; 2N4R; 2N4S;
3D   2N4T; 2N4U; 2N4V; 2N4W; 2N8S; 2N8T; 2N8U; 2NNT; 2OEI; 2OP7; 2Q5A; 2RLY;
3D   2RM0; 2XP3; 2XP4; 2XP5; 2XP6; 2XP7; 2XP8; 2XP9; 2XPA; 2XPB; 2YSB; 2YSC;
3D   2YSD; 2YSE; 2YSF; 2YSG; 2YSH; 2YSI; 2ZAJ; 2ZQS; 2ZQT; 2ZQU; 2ZQV; 2ZR4;
3D   2ZR5; 2ZR6; 3KAB; 3KAD; 3KAF; 3KAG; 3KAH; 3KAI; 3KCE; 3L4H; 3LE4; 3NTP;
3D   3ODK; 3OLM; 3OOB; 3TC5; 3TCZ; 3TDB; 3WH0; 4GWT; 4GWV; 4LCD; 4N7F; 4N7H;
3D   4QIB; 4REX; 4ROF; 4U84; 4U85; 4U86; 5AHT; 5B3Z; 5CQ2; 5DWS; 5DZD; 5TJ7;
3D   5UY9; 5VTI; 5VTJ; 5VTK; 5XMC; 5YDX; 5YDY;
PR   PRU00224;
DO   PDOC50020;
//
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