ID ALDOKETO_REDUCTASE_3; PATTERN.
AC PS00063;
DT 01-APR-1990 CREATED; 01-APR-2006 DATA UPDATE; 02-JUN-2021 INFO UPDATE.
DE Aldo/keto reductase family putative active site signature.
PA [LIVM]-[PAIV]-[KR]-[ST]-{EPQG}-{RFI}-x(2)-R-{SVAF}-x-[GSTAEQK]-[NSL]-x-
PA {LVRI}-[LIVMFA].
NR /RELEASE=2021_03,565254;
NR /TOTAL=179(179); /POSITIVE=126(126); /UNKNOWN=0(0); /FALSE_POS=53(53);
NR /FALSE_NEG=71; /PARTIAL=2;
CC /TAXO-RANGE=??EP?; /MAX-REPEAT=1;
CC /SITE=8,active_site(?);
CC /VERSION=2;
DR P26690 , 6DCS_SOYBN , T; Q6AZW2 , A1A1A_DANRE, T;
DR Q568L5 , A1A1B_DANRE, T; Q3ZCJ2 , AK1A1_BOVIN, T;
DR Q5ZK84 , AK1A1_CHICK, T; P14550 , AK1A1_HUMAN, T;
DR Q9JII6 , AK1A1_MOUSE, T; P50578 , AK1A1_PIG , T;
DR Q5R5D5 , AK1A1_PONAB, T; P51635 , AK1A1_RAT , T;
DR Q6GMC7 , AK1A1_XENLA, T; Q28FD1 , AK1A1_XENTR, T;
DR O60218 , AK1BA_HUMAN, T; Q04828 , AK1C1_HUMAN, T;
DR Q95JH7 , AK1C1_MACFA, T; Q95JH6 , AK1C1_MACFU, T;
DR Q5REQ0 , AK1C1_PONAB, T; P52895 , AK1C2_HUMAN, T;
DR P42330 , AK1C3_HUMAN, T; Q5R7C9 , AK1C3_PONAB, T;
DR P17516 , AK1C4_HUMAN, T; Q95JH5 , AK1C4_MACFA, T;
DR Q95JH4 , AK1C4_MACFU, T; D3ZF77 , AK1CA_RAT , T;
DR Q1XAA8 , AK1CN_HORSE, T; Q6W8P9 , AK1CO_HORSE, T;
DR P51857 , AK1D1_HUMAN, T; Q8VCX1 , AK1D1_MOUSE, T;
DR Q9TV64 , AK1D1_RABIT, T; P31210 , AK1D1_RAT , T;
DR H9JTG9 , AK2E4_BOMMO, T; Q8K023 , AKC1H_MOUSE, T;
DR P51652 , AKC1H_RAT , T; Q9DCT1 , AKCL2_MOUSE, T;
DR P82125 , AKCL2_PIG , T; Q5U1Y4 , AKCL2_RAT , T;
DR O80944 , AKRC8_ARATH, T; Q0PGJ6 , AKRC9_ARATH, T;
DR Q84TF0 , AKRCA_ARATH, T; Q9M338 , AKRCB_ARATH, T;
DR P21300 , ALD1_MOUSE , T; O08782 , ALD2_CRIGR , T;
DR P45377 , ALD2_MOUSE , T; P16116 , ALDR_BOVIN , T;
DR P23901 , ALDR_HORVU , T; P15121 , ALDR_HUMAN , T;
DR P45376 , ALDR_MOUSE , T; P80276 , ALDR_PIG , T;
DR P15122 , ALDR_RABIT , T; P07943 , ALDR_RAT , T;
DR Q54NZ7 , ALRB_DICDI , T; P38115 , ARA1_YEAST , T;
DR Q9SQ70 , COR11_PAPSO, T; Q9SQ69 , COR12_PAPSO, T;
DR Q9SQ68 , COR13_PAPSO, T; Q9SQ67 , COR14_PAPSO, T;
DR B9VRJ2 , COR15_PAPSO, T; Q9SQ64 , COR2_PAPSO , T;
DR P17264 , CRO_LITCT , T; P02532 , CRO_RANTE , T;
DR P52898 , DDBX_BOVIN , T; P70694 , DHB5_MOUSE , T;
DR P23457 , DIDH_RAT , T; Q8XBT6 , DKGA_ECO57 , T;
DR Q46857 , DKGA_ECOLI , T; P58744 , DKGA_SALTI , T;
DR Q8ZM06 , DKGA_SALTY , T; Q8ZI40 , DKGA_YERPE , T;
DR P15339 , DKGB_CORSS , T; Q0PCF4 , DMAS1_HORVU, T;
DR B4F9A4 , DMAS1_MAIZE, T; Q10PE7 , DMAS1_ORYSJ, T;
DR W5DYE3 , DMS1A_WHEAT, T; A0A1D5XGW0, DMS1B_WHEAT, T;
DR A0A1X9QHJ0, DMS1D_WHEAT, T; Q01213 , DTDH_MUCMU , T;
DR Q3ZFI7 , GAR1_HYPJE , T; P14065 , GCY1_YEAST , T;
DR Q0GYU4 , GLD2_HYPJE , T; P38715 , GRE3_YEAST , T;
DR O32210 , GR_BACSU , T; E7C196 , MER_ERYCB , T;
DR Q9QXN5 , MIOX_MOUSE , T; Q9QXN4 , MIOX_RAT , T;
DR Q02198 , MORA_PSEPU , T; Q8CG09 , MRP1_RAT , T;
DR Q7G764 , NADO1_ORYSJ, T; Q7G765 , NADO2_ORYSJ, T;
DR P80508 , PE2R_RABIT , T; P05980 , PGFS1_BOVIN, T;
DR P52897 , PGFS2_BOVIN, T; P22045 , PGFS_LEIMA , T;
DR Q4DJ07 , PGFS_TRYCC , T; P28475 , S6PD_MALDO , T;
DR P0DKI7 , STORR_PAPSO, T; C5FFQ7 , XYL1_ARTOC , T;
DR A1CRI1 , XYL1_ASPCL , T; B0XNR0 , XYL1_ASPFC , T;
DR B8N195 , XYL1_ASPFN , T; Q4WJT9 , XYL1_ASPFU , T;
DR A2Q8B5 , XYL1_ASPNC , T; Q9P8R5 , XYL1_ASPNG , T;
DR Q2UKD0 , XYL1_ASPOR , T; Q0CUL0 , XYL1_ASPTN , T;
DR Q8X195 , XYL1_CANBO , T; Q6Y0Z3 , XYL1_CANPA , T;
DR O74237 , XYL1_CANTE , T; O13283 , XYL1_CANTR , T;
DR Q5BGA7 , XYL1_EMENI , T; A1D4E3 , XYL1_NEOFI , T;
DR O94735 , XYL1_PICGU , T; P31867 , XYL1_PICST , T;
DR Q9P430 , XYL1_SCHSH , T; P87039 , XYL2_CANTR , T;
DR A3PXS9 , Y1918_MYCSJ, T; A3PXT0 , Y1919_MYCSJ, T;
DR Q1BAN7 , Y1938_MYCSS, T; A1UEC5 , Y1984_MYCSK, T;
DR A1UEC6 , Y1985_MYCSK, T; A0QV10 , Y2408_MYCS2, T;
DR A4TE41 , Y4205_MYCGI, T; O14088 , YER5_SCHPO , T;
DR P47137 , YJ66_YEAST , T; Q09632 , YOF5_CAEEL , T;
DR Q12458 , YPR1_YEAST , T; O34678 , YTBE_BACSU , T;
DR P49261 , CROB_LEPLU , P; P55804 , DHGP_ASPNG , P;
DR C9JRZ8 , AK1BF_HUMAN, N; P82809 , AK1CD_MESAU, N;
DR Q8VC28 , AK1CD_MOUSE, N; Q91WR5 , AK1CL_MOUSE, N;
DR Q6AYQ2 , AK1CL_RAT , N; Q5T2L2 , AKCL1_HUMAN, N;
DR Q96JD6 , AKCL2_HUMAN, N; Q4R802 , AKCL2_MACFA, N;
DR B8ASB2 , AKR1_ORYSI , N; Q0JE32 , AKR1_ORYSJ , N;
DR C6TBN2 , AKR1_SOYBN , N; A2XRZ0 , AKR2_ORYSI , N;
DR Q7XT99 , AKR2_ORYSJ , N; A2XRZ6 , AKR3_ORYSI , N;
DR Q7XQ45 , AKR3_ORYSJ , N; P77256 , AKRMG_ECOLI, N;
DR P74308 , AKR_SYNY3 , N; P27800 , ALDX_SPOSA , N;
DR Q9C5B9 , ALKR1_ARATH, N; Q84M96 , ALKR2_ARATH, N;
DR O22707 , ALKR3_ARATH, N; Q93ZN2 , ALKR4_ARATH, N;
DR Q9ASZ9 , ALKR5_ARATH, N; F4HPY8 , ALKR6_ARATH, N;
DR Q6IMN8 , ALRA_DICDI , N; Q55FL3 , ALRC_DICDI , N;
DR Q04212 , ARA2_YEAST , N; P06632 , DKGA_CORSC , N;
DR Q8X7Z7 , DKGB_ECO57 , N; P30863 , DKGB_ECOLI , N;
DR Q8Z988 , DKGB_SALTI , N; Q8ZRM7 , DKGB_SALTY , N;
DR Q8ZH36 , DKGB_YERPE , N; Q52472 , FCDH_PSESP , N;
DR O81884 , GALDH_ARATH, N; Q0GYU5 , GLD1_HYPJE , N;
DR P80874 , GS69_BACSU , N; O13848 , I3ACR_SCHPO, N;
DR P46336 , IOLS_BACSU , N; Q07551 , KAR_YEAST , N;
DR P82810 , MORA_RABIT , N; Q3L181 , PERR_RAUSE , N;
DR Q9GV41 , PGFS_TRYBB , N; O14295 , PLR1_SCHPO , N;
DR Q06494 , PLR1_YEAST , N; O94521 , PLR2_SCHPO , N;
DR G4MZI3 , PRD1_MAGO7 , N; Q876L8 , XYL1_HYPJE , N;
DR P49378 , XYL1_KLULA , N; G4N708 , XYL1_MAGO7 , N;
DR P78736 , XYL1_PACTA , N; B8ZS00 , Y1669_MYCLB, N;
DR O69462 , Y1669_MYCLE, N; B2HIJ9 , Y1744_MYCMM, N;
DR A0PQ11 , Y1987_MYCUA, N; A1T726 , Y2161_MYCVP, N;
DR A0QV09 , Y2407_MYCS2, N; P9WQA4 , Y2971_MYCTO, N;
DR P9WQA5 , Y2971_MYCTU, N; A1KMW6 , Y2993_MYCBP, N;
DR Q7TXI6 , Y2996_MYCBO, N; A5U6Y1 , Y2999_MYCTA, N;
DR Q73VK6 , Y3007_MYCPA, N; A0QJ99 , Y3816_MYCA1, N;
DR Q73SC5 , Y4149_MYCPA, N; A0QL30 , Y4483_MYCA1, N;
DR O42888 , YBN4_SCHPO , N; Q10494 , YDG7_SCHPO , N;
DR O14125 , YEZB_SCHPO , N; O94315 , YH5B_SCHPO , N;
DR Q9C1X5 , YKW2_SCHPO , N;
DR Q42400 , AAP1_ARATH , F; P92934 , AAP6_ARATH , F;
DR B1MLV9 , ATPFD_MYCA9, F; Q752Q2 , BST1_ASHGO , F;
DR Q96F05 , CK024_HUMAN, F; Q2U0Q9 , EIF3C_ASPOR, F;
DR Q0CVT0 , EIF3C_ASPTN, F; Q0ZB76 , EIF3C_BOMMO, F;
DR Q9ZCZ1 , FAD3_RICPR , F; Q1HCM0 , FGFP3_MOUSE, F;
DR Q22RG7 , H34_TETTS , F; Q7N3S7 , HMUV_PHOLL , F;
DR Q99PI5 , LPIN2_MOUSE, F; Q3KE48 , MACB2_PSEPF, F;
DR A9IWA4 , MURC_BART1 , F; Q8UIF2 , MUTS_AGRFC , F;
DR A8I275 , MUTS_AZOC5 , F; Q6G542 , MUTS_BARHE , F;
DR Q6G0X1 , MUTS_BARQU , F; A9ILT1 , MUTS_BART1 , F;
DR Q2YNZ0 , MUTS_BRUA2 , F; Q57FM9 , MUTS_BRUAB , F;
DR A9M792 , MUTS_BRUC2 , F; Q8YES6 , MUTS_BRUME , F;
DR A5VN83 , MUTS_BRUO2 , F; B0CIQ5 , MUTS_BRUSI , F;
DR Q8G310 , MUTS_BRUSU , F; Q11B27 , MUTS_CHESB , F;
DR A6WV86 , MUTS_OCHA4 , F; Q2KD76 , MUTS_RHIEC , F;
DR Q1MMA5 , MUTS_RHIL3 , F; Q1K8F6 , NAGS_NEUCR , F;
DR B2B2C5 , NAGS_PODAN , F; Q8RXH2 , NUP85_ARATH, F;
DR Q90941 , PB1_CHICK , F; Q86U86 , PB1_HUMAN , F;
DR Q1J2D0 , PTA_DEIGD , F; P95991 , RL13_SACS2 , F;
DR Q6B8S1 , RR18_GRATL , F; Q1KVT1 , RR18_TETOB , F;
DR P62659 , RS18_THET2 , F; Q5SLQ0 , RS18_THET8 , F;
DR P80382 , RS18_THETH , F; A0T0G5 , SECA_PHATC , F;
DR Q045X9 , SYE_LACGA , F; Q74L27 , SYE_LACJO , F;
DR A0RQ93 , TRMB_CAMFF , F; Q6CSG8 , U507_KLULA , F;
DR Q9ZCE0 , XERC_RICPR , F; Q68VT2 , XERC_RICTY , F;
DR Q6R7C1 , Y109_OSHVF , F; Q8DB14 , Y2014_VIBVU, F;
DR Q7MIW1 , Y2402_VIBVY, F;
3D 1ABN; 1ADS; 1AE4; 1AFS; 1AH0; 1AH3; 1AH4; 1AZ1; 1AZ2; 1C9W; 1CWN; 1DLA;
3D 1EF3; 1EKO; 1EL3; 1FRB; 1HQT; 1IEI; 1IHI; 1J96; 1JEZ; 1K8C; 1LWI; 1MAR;
3D 1MI3; 1MRQ; 1MZR; 1PWL; 1PWM; 1Q13; 1Q5M; 1R38; 1RAL; 1RY0; 1RY8; 1S1P;
3D 1S1R; 1S2A; 1S2C; 1SM9; 1T40; 1T41; 1US0; 1X96; 1X97; 1X98; 1XF0; 1XJB;
3D 1YE4; 1YE6; 1Z3N; 1Z89; 1Z8A; 1Z9A; 1ZQ5; 1ZUA; 2ACQ; 2ACR; 2ACS; 2ACU;
3D 2AGT; 2ALR; 2BGQ; 2BGS; 2DUX; 2DUZ; 2DV0; 2F2K; 2F38; 2FGB; 2FVL; 2FZ8;
3D 2FZ9; 2FZB; 2FZD; 2HDJ; 2HUO; 2HV5; 2HVN; 2HVO; 2I16; 2I17; 2IKG; 2IKH;
3D 2IKI; 2IKJ; 2INE; 2INZ; 2IPJ; 2IPW; 2IQ0; 2IQD; 2IS7; 2ISF; 2J8T; 2NVC;
3D 2NVD; 2PD5; 2PD9; 2PDB; 2PDC; 2PDF; 2PDG; 2PDH; 2PDI; 2PDJ; 2PDK; 2PDL;
3D 2PDM; 2PDN; 2PDP; 2PDQ; 2PDU; 2PDW; 2PDX; 2PDY; 2PEV; 2PF8; 2PFH; 2PZN;
3D 2QXW; 2R24; 2VDG; 3B3D; 3BCJ; 3BUR; 3BUV; 3BV7; 3BXD; 3C3U; 3CAQ; 3CAS;
3D 3CAV; 3CMF; 3COT; 3CV7; 3D3F; 3DN5; 3DOP; 3F7J; 3FX4; 3G1R; 3G5E; 3GHR;
3D 3GHS; 3GHT; 3GHU; 3GUG; 3H4G; 3H7R; 3H7U; 3LBO; 3LD5; 3LEN; 3LEP; 3LQG;
3D 3LQL; 3LZ3; 3LZ5; 3M0I; 3M4H; 3M64; 3MB9; 3MC5; 3NTY; 3ONB; 3ONC; 3P2V;
3D 3Q65; 3Q67; 3R43; 3R58; 3R6I; 3R7M; 3R8G; 3R8H; 3R94; 3RX2; 3RX3; 3RX4;
3D 3S3G; 3T42; 3U2C; 3UFY; 3UG8; 3UGR; 3UWE; 3UZW; 3UZX; 3UZY; 3UZZ; 3V35;
3D 3V36; 3WCZ; 4DBS; 4DBU; 4DBW; 4DZ5; 4F40; 4FA3; 4FAL; 4FAM; 4FZI; 4G5D;
3D 4GA8; 4GAB; 4GAC; 4GCA; 4GIE; 4GQ0; 4GQG; 4H7C; 4HMN; 4I5X; 4ICC; 4IGS;
3D 4IJC; 4IJR; 4JIH; 4JII; 4JIR; 4JQ1; 4JQ2; 4JQ3; 4JQ4; 4JQA; 4JTQ; 4JTR;
3D 4L1W; 4L1X; 4LAU; 4LAZ; 4LB3; 4LB4; 4LBR; 4LBS; 4NKC; 4PR4; 4PRR; 4PRT;
3D 4PUU; 4PUW; 4Q7B; 4QBX; 4QR6; 4QX4; 4QXI; 4RPQ; 4WDT; 4WDU; 4WDW; 4WDX;
3D 4WEV; 4WRH; 4XO6; 4XO7; 4XVD; 4XVE; 4XZH; 4XZI; 4XZL; 4XZM; 4XZN; 4YS1;
3D 4YU1; 4YVP; 4YVV; 4YVX; 4ZFC; 5HA7; 5HNT; 5HNU; 5LIK; 5LIU; 5LIW; 5LIX;
3D 5LIY; 5M2F; 5OU0; 5OUJ; 5OUK; 5Y7N; 5Z6T; 5Z6U; 6A7A; 6A7B; 6F2U; 6F78;
3D 6F7R; 6F81; 6F82; 6F84; 6F8O; 6GXK; 6IJX; 6SYW; 6T27; 6T3P; 6T5G; 6T7Q;
3D 6TD8; 6TUC; 6TUF; 6TXP; 6XUM; 6Y03; 6Y1P; 7C7F; 7C7G; 7C7H;
DO PDOC00061;
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