ID B_KETOACYL_SYNTHASE; PATTERN.
AC PS00606;
DT 01-DEC-1991 CREATED; 01-APR-2006 DATA UPDATE; 25-MAY-2022 INFO UPDATE.
DE Beta-ketoacyl synthases active site.
PA G-{A}-{KGR}-x(2)-[LIVMFTAP]-{R}-x-[AGC]-C-[STA](2)-[STAG]-x(2)-{LI}-
PA [LIVMF].
NR /RELEASE=2022_02,567483;
NR /TOTAL=376(365); /POSITIVE=367(356); /UNKNOWN=0(0); /FALSE_POS=9(9);
NR /FALSE_NEG=14; /PARTIAL=2;
CC /TAXO-RANGE=??EP?; /MAX-REPEAT=2;
CC /SITE=9,active_site;
CC /VERSION=2;
DR Q0CRQ5 , 5MOAS_ASPTN, T; G4MVZ2 , ACE1_MAGO7 , T;
DR A0A1L9WQM9, ACRA_ASPA1 , T; R4WH05 , ACRS2_ALTAL, T;
DR Q02059 , ACTI1_STRCO, T; D9N1A1 , ACTS3_ALTAL, T;
DR A0A1L9WN37, ACUA_ASPA1 , T; A2QX22 , ADAA_ASPNC , T;
DR G3KLH6 , ADAA_ASPNG , T; A0A1Y0BRF1, ADRD_PENRO , T;
DR B6HV32 , ADRD_PENRW , T; V5Y0F7 , AF161_ALTAL, T;
DR Q8TGA2 , AFLA_ASPPU , T; Q5BEJ6 , AFOE_EMENI , T;
DR B8N8R0 , AFVB_ASPFN , T; A0A411PQP9, AGPKS_PAEDI, T;
DR Q4WZA8 , ALB1_ASPFU , T; A0A1L9UCG2, ALBA_ASPBC , T;
DR G3XLL5 , ALBA_ASPNA , T; A2QUI2 , ALBA_ASPNC , T;
DR C8VJR7 , ALNA_EMENI , T; A0A3G9H990, ALT1_ALTAL , T;
DR Q5KTM9 , ALT5_ALTSO , T; A0A097ZPE0, ANDM_EMEVA , T;
DR Q5ATG8 , APDA_EMENI , T; S0DL59 , APF5_GIBF5 , T;
DR Q5B0D0 , APTA_EMENI , T; G1XU04 , AR283_ARTOA, T;
DR A0A2H3CTK0, ARMB_ARMGA , T; I3ZNU9 , ARMB_ARMME , T;
DR A0A284RE13, ARMB_ARMOS , T; A0A5C1RD96, ASC5_DIDFA , T;
DR A0A5C1RDA3, ASC7_DIDFA , T; A0A455R5P9, ASCC_ACREG , T;
DR Q0D159 , AT325_ASPTN, T; Q5AV00 , ATNF_EMENI , T;
DR A0A455LLX1, ATNH_ARTSZ , T; Q0CJ59 , ATX_ASPTN , T;
DR A0A0M4L8I7, AURA_CALAK , T; A0A0U5GFS8, AUSA_ASPCI , T;
DR Q5ATJ7 , AUSA_EMENI , T; A0A0F7U103, AUSA_PENBI , T;
DR G3XMD1 , AZAB_ASPNA , T; Q0CF73 , AZPB2_ASPTN, T;
DR A0A0C6E0I7, BET1_NEOBT , T; S0DZM7 , BIK1_GIBF5 , T;
DR B1GVX7 , BOA6_BOTFB , T; A0A411L027, BUAA_ASPBU , T;
DR A0A1V6PAF7, CALA_PENDC , T; A0A0K0MCJ4, CAZM_CHAGB , T;
DR A1CLY8 , CCSA_ASPCL , T; P39525 , CEM1_YEAST , T;
DR Q2HBN0 , CGHG_CHAGB , T; Q2HEW5 , CHEA_CHAGB , T;
DR Q65Z23 , CITS_MONPU , T; A0A161CEU9, CITS_MONRU , T;
DR A0A125R003, CLA3_CLACD , T; A0A481WQB6, CLAF_PENCR , T;
DR A0A345BJN0, CLZ14_COCLU, T; G3J453 , CM3B_CORMM , T;
DR A0A0A2JW91, CNSI_PENEN , T; B6F209 , CPAS_ASPOZ , T;
DR A0A2G5IC96, CTB1_CERBT , T; Q6DQW3 , CTB1_CERNC , T;
DR Q0C9L7 , CTVA_ASPTN , T; L7XAV2 , CURS2_ASPTE, T;
DR D2E9X0 , DEP5_ALTBR , T; A0A0N0DCA3, DEP5_FUSLA , T;
DR A0A0N7D745, DHC5_ALTCI , T; A0A4P8DJU2, DMPKS_CRYX8, T;
DR A0A4P8DJV2, DMXL2_CRYX8, T; P9WEX0 , DPASA_ARTSH, T;
DR A0A1B7YCC9, DPCHA_COLHI, T; I1RL11 , DPFGA_GIBZE, T;
DR P9WEX6 , DPMAA_METAN, T; K2QVI8 , DPMPA_MACPH, T;
DR Q5BA83 , EASB_EMENI , T; Q0UI00 , ELCA_PHANO , T;
DR S4W172 , EQXS_FUSHE , T; S0DS59 , EQXS_GIBF5 , T;
DR Q03131 , ERYA1_SACER, T; Q03132 , ERYA2_SACER, T;
DR Q03133 , ERYA3_SACER, T; A0A4P8GHJ1, EUPA_PHOSX , T;
DR P57193 , FABB_BUCAI , T; Q8KA28 , FABB_BUCAP , T;
DR Q89AY4 , FABB_BUCBP , T; P0A954 , FABB_ECOL6 , T;
DR P0A953 , FABB_ECOLI , T; P43710 , FABB_HAEIN , T;
DR Q02K94 , FABB_PSEAB , T; O34340 , FABF_BACSU , T;
DR Q83E37 , FABF_COXBU , T; P0AAI7 , FABF_ECO57 , T;
DR P0AAI6 , FABF_ECOL6 , T; P0AAI5 , FABF_ECOLI , T;
DR P56902 , FABF_RHIME , T; P0AAI8 , FABF_SHIFL , T;
DR Q5HHA1 , FABF_STAAC , T; Q99VA6 , FABF_STAAM , T;
DR Q7A6F8 , FABF_STAAN , T; Q6GIA3 , FABF_STAAR , T;
DR Q6GAU2 , FABF_STAAS , T; Q5TKS0 , FABF_STAAU , T;
DR Q8NXE1 , FABF_STAAW , T; P73283 , FABF_SYNY3 , T;
DR Q9KQH9 , FABF_VIBCH , T; P55338 , FABF_VIBHA , T;
DR P43098 , FAS2_CANAX , T; G8BAW7 , FAS2_CANPC , T;
DR P78615 , FAS2_EMEND , T; Q765N2 , FAS2_LACKL , T;
DR P15368 , FAS2_PENPA , T; Q10289 , FAS2_SCHPO , T;
DR A0A0D1DNX1, FAS2_USTMA , T; P19097 , FAS2_YEAST , T;
DR P36189 , FAS_ANSAN , T; Q71SP7 , FAS_BOVIN , T;
DR P12276 , FAS_CHICK , T; P49327 , FAS_HUMAN , T;
DR P19096 , FAS_MOUSE , T; P12785 , FAS_RAT , T;
DR A0A7L8UVC9, FFSA_ASPFV , T; Q4WKW9 , FGNA_ASPFU , T;
DR B8NYX0 , FLUP_ASPFN , T; Q4WAY3 , FMAB_ASPFU , T;
DR A0A0S6XH49, FRBB_BLOB1 , T; A0A0E4AZP0, FSA1_FUSSF , T;
DR Q5SBL6 , FSDS_FUSHE , T; I1S166 , FSL1_GIBZE , T;
DR S0DTP6 , FSR1_GIBF5 , T; A0A0D2YG10, FUB1_FUSO4 , T;
DR S0DRI1 , FUB1_GIBF5 , T; W7MT31 , FUB1_GIBM7 , T;
DR S0EET5 , FUJ1_GIBF5 , T; W7LKX1 , FUM1_GIBM7 , T;
DR S0EEY3 , FUS1_GIBF5 , T; W7MLD7 , FUS1_GIBM7 , T;
DR I1RVD8 , FUSA1_GIBZE, T; A0A6S5ZY48, G433_FUSSX , T;
DR Q0CCY3 , GEDC_ASPTN , T; S3D9F1 , GLOL_GLAL2 , T;
DR E9KMQ2 , GRA1_CLAGR , T; I1R9A6 , GRA9_GIBZE , T;
DR D7PI15 , GSFA_PENAE , T; M2YJJ3 , HEXA_DOTSN , T;
DR A0A2Z5TM64, HIMA_ASPJA , T; B3FWS8 , HPM3_HYPSB , T;
DR M2YKT6 , HPS1_DOTSN , T; A0A482N9V7, ICCA_TALVA , T;
DR P0DO30 , ILIA_NEOS2 , T; P41175 , KAS1_STRCM , T;
DR Q02578 , KAS1_STRCN , T; P23155 , KAS1_STRCO , T;
DR P16538 , KAS1_STRGA , T; Q05356 , KAS1_STRHA , T;
DR P43678 , KAS1_STRRM , T; P16540 , KAS1_STRVN , T;
DR P52410 , KASC1_ARATH, T; P23902 , KASC1_HORVU, T;
DR Q9C9P4 , KASC2_ARATH, T; Q8L3X9 , KASM_ARATH , T;
DR A0A179H0J7, LCSC_PURLI , T; Q9Y8A5 , LOVB_ASPTE , T;
DR Q0C8M3 , LOVB_ASPTN , T; Q9Y7D5 , LOVF_ASPTE , T;
DR Q0C8L6 , LOVF_ASPTN , T; A0A6J4B487, LUC5_FUSSX , T;
DR A0A2P1DP91, MACA_PENTR , T; Q02251 , MCAS_MYCBO , T;
DR Q8J0F7 , MLCA_PENCI , T; Q8J0F5 , MLCB_PENCI , T;
DR A0A0A0RM07, MLNS_PHANO , T; Q3S2T9 , MOKA_MONPI , T;
DR Q3S2U6 , MOKB_MONPI , T; A0A0B5KU17, MPAC2_PENBR, T;
DR F1DBA9 , MPAC_PENBR , T; W6QL47 , MPAC_PENRF , T;
DR A0A0R8YWJ7, MPAS_CLAUC , T; P22367 , MSAS_PENPA , T;
DR A0A089QRB9, MSL3_MYCTU , T; Q7TXK8 , MSL7_MYCBO , T;
DR B2HIL7 , MSL7_MYCMM , T; Q9R9J1 , MYCA_BACIU , T;
DR G2Q9A5 , MYCA_MYCTT , T; P04684 , NODE_RHILT , T;
DR P04683 , NODE_RHILV , T; P06230 , NODE_RHIME , T;
DR P72331 , NODE_RHIS3 , T; P06231 , NOE4_RHIML , T;
DR D4AWH3 , NSCA_ARTBC , T; E4V2N2 , NSCA_ARTGP , T;
DR C5FM57 , NSCA_ARTOC , T; Q4WA61 , NSCA_ASPFU , T;
DR A1D8I9 , NSCA_NEOFI , T; F2PWS5 , NSCA_TRIEC , T;
DR F2T0M0 , NSCA_TRIRC , T; F2S6Z9 , NSCA_TRIT1 , T;
DR D4CZZ2 , NSCA_TRIVH , T; A0A2I1C3X5, NSRB_ASPN1 , T;
DR A0A455M2Y3, NTNH_NECSZ , T; A0A2I1BSV9, NVFA_ASPN1 , T;
DR Q07017 , OL56_STRAT , T; P9WEQ0 , OLCA_PENCN , T;
DR J4UHQ6 , OPS1_BEAB2 , T; Q5AUX1 , ORSA_EMENI , T;
DR A0A1R3RGK0, OTAA_ASPC5 , T; A2R6H1 , OTAA_ASPNC , T;
DR Q0VCA7 , OXSM_BOVIN , T; Q9NWU1 , OXSM_HUMAN , T;
DR Q9D404 , OXSM_MOUSE , T; A1CFL8 , PATK_ASPCL , T;
DR A0A075TRC0, PATK_PENEN , T; W3X7U2 , PFMAE_PESFW, T;
DR Q7TVK8 , PHAS_MYCBO , T; A1KQG0 , PHAS_MYCBP , T;
DR A5U9F4 , PHAS_MYCTA , T; P9WQE8 , PHAS_MYCTO , T;
DR P9WQE9 , PHAS_MYCTU , T; A0A2Z5XAL7, PHM1_PYRSX , T;
DR A0A142C799, PHNA_PENHR , T; M1WG96 , PIG15_CLAP2, T;
DR Q9ZGI5 , PIKA1_STRVZ, T; Q9ZGI4 , PIKA2_STRVZ, T;
DR Q9ZGI3 , PIKA3_STRVZ, T; Q9ZGI2 , PIKA4_STRVZ, T;
DR Q5B8A0 , PKFA_EMENI , T; Q5AXA9 , PKGA_EMENI , T;
DR Q5BBP8 , PKHA_EMENI , T; Q5B7V0 , PKIB_EMENI , T;
DR B0G103 , PKS10_DICDI, T; I1RF58 , PKS12_GIBZE, T;
DR I6XD69 , PKS12_MYCTU, T; Q559A9 , PKS13_DICDI, T;
DR I6X8D2 , PKS13_MYCTU, T; Q558Y6 , PKS14_DICDI, T;
DR P96284 , PKS15_MYCTU, T; Q869W9 , PKS16_DICDI, T;
DR Q869X2 , PKS17_DICDI, T; Q54TW0 , PKS18_DICDI, T;
DR Q54T36 , PKS19_DICDI, T; G4N296 , PKS19_MAGO7, T;
DR A0A0H4ADX3, PKS19_PHANO, T; Q55E72 , PKS1_DICDI , T;
DR A7UMW1 , PKS1_ELSFA , T; A0A0B4FTU6, PKS1_METAF , T;
DR A0A2U8NEV6, PKS1_METAQ , T; A0A2U8NET4, PKS1_METAS , T;
DR A0A0B4ESU9, PKS1_METBS , T; A0A0B4G9F9, PKS1_METGA , T;
DR A0A0B4H4F0, PKS1_METMF , T; E9F646 , PKS1_METRA , T;
DR A5PHD6 , PKS1_SARSH , T; F9XMW3 , PKS1_ZYMTI , T;
DR B0G138 , PKS21_DICDI, T; Q54QD3 , PKS22_DICDI, T;
DR Q54QD1 , PKS23_DICDI, T; Q54KU5 , PKS24_DICDI, T;
DR Q54KU3 , PKS25_DICDI, T; B8MYS6 , PKS27_ASPFN, T;
DR Q54G30 , PKS27_DICDI, T; B0G170 , PKS28_DICDI, T;
DR Q54FQ3 , PKS29_DICDI, T; N4WHA7 , PKS2_COCH4 , T;
DR Q55DM7 , PKS2_DICDI , T; A0A0B4FLB2, PKS2_METAF , T;
DR E9EHG2 , PKS2_METAQ , T; A0A0B4H8J1, PKS2_METBS , T;
DR A0A0B4I1L1, PKS2_METGA , T; A0A0B4I1J8, PKS2_METMF , T;
DR E9ET39 , PKS2_METRA , T; Q54FQ2 , PKS30_DICDI, T;
DR Q54FQ1 , PKS31_DICDI, T; Q54FP8 , PKS32_DICDI, T;
DR Q54FN7 , PKS33_DICDI, T; Q54FN2 , PKS34_DICDI, T;
DR Q54FD2 , PKS38_DICDI, T; Q54FC8 , PKS39_DICDI, T;
DR Q55CN6 , PKS3_DICDI , T; Q54ED7 , PKS40_DICDI, T;
DR Q54ED6 , PKS41_DICDI, T; Q54D44 , PKS42_DICDI, T;
DR Q54B51 , PKS44_DICDI, T; Q86JI5 , PKS5_DICDI , T;
DR A0R1E8 , PKS5_MYCS2 , T; O53901 , PKS5_MYCTU , T;
DR B0G0Z9 , PKS6_DICDI , T; B0G100 , PKS7_DICDI , T;
DR M3A326 , PKS81_PSEFD, T; B0G101 , PKS8_DICDI , T;
DR Q86AE3 , PKS9_DICDI , T; P40806 , PKSJ_BACSU , T;
DR Q05470 , PKSL_BACSU , T; P40872 , PKSM_BACSU , T;
DR O31782 , PKSN_BACSU , T; O31784 , PKSR_BACSU , T;
DR S7ZFK6 , POXE_PENO1 , T; A0A1W5T1U1, POXE_PENOX , T;
DR Q7TXM0 , PPSA_MYCBO , T; P9WQE6 , PPSA_MYCTO , T;
DR P9WQE7 , PPSA_MYCTU , T; Q2UB00 , PPSB_ASPOR , T;
DR Q7TXL9 , PPSB_MYCBO , T; P9WQE4 , PPSB_MYCTO , T;
DR P9WQE5 , PPSB_MYCTU , T; Q7TXL8 , PPSC_MYCBO , T;
DR P96202 , PPSC_MYCTU , T; Q7TXL7 , PPSD_MYCBO , T;
DR P9WQE2 , PPSD_MYCTO , T; P9WQE3 , PPSD_MYCTU , T;
DR Q7TXL6 , PPSE_MYCBO , T; P9WQE0 , PPSE_MYCTO , T;
DR P9WQE1 , PPSE_MYCTU , T; A0A1E1FFN8, PRHL_PENBI , T;
DR A0A089FSA4, PRLS_FUNXX , T; Q4WAZ9 , PSOA_ASPFU , T;
DR A0A067XNI2, PTAA_PESFW , T; A0A3T0QHT6, PVHA_TALVA , T;
DR Q4WLD4 , PYR2_ASPFU , T; P9WEZ4 , PYTA_ASPTE , T;
DR Q0CZH1 , PYTA_ASPTN , T; A0A2V5GX43, PYVA_ASPV1 , T;
DR C5H882 , RADS2_FLOCH, T; B3FWT6 , RDC1_METCM , T;
DR A0A1U8QN18, SDGA_EMENI , T; D7UQ44 , SOL1_ALTSO , T;
DR G0R6S9 , SORB_HYPJQ , T; A0A384XH94, SPKS1_STRTC, T;
DR A0A3G1DJF3, SQHKS_PHOSM, T; Q7SHI6 , SRDA_NEUCR , T;
DR A0A193PS74, STBA_STABI , T; Q00681 , STCJ_EMENI , T;
DR Q0UK48 , STHA_PHANO , T; Q54FI3 , STLB_DICDI , T;
DR E9F5E7 , SUBA_METRA , T; G4N137 , TAS1_MAGO7 , T;
DR A0A0F7GFS4, TASS_HAPIR , T; Q0D1N9 , TERA_ASPTN , T;
DR Q2T4N1 , THAG_BURTA , T; A0A0G0AID6, THNA_TRIHA , T;
DR Q4WQZ5 , TPCC_ASPFU , T; A0A481WNP4, TRAA_PENCR , T;
DR B8M9J9 , TROPA_TALSN, T; Q0C8A4 , TRT4_ASPTN , T;
DR A0A2L0P0K3, TWMB_TALWO , T; A0A1B5L6A0, USTP_USTVR , T;
DR P9WEV0 , VALA_ASPTE , T; A0A443HK81, VDTA1_BYSSP, T;
DR A0A1V6NYI6, VERA_PENPO , T; G9N4B2 , VIRA_HYPVG , T;
DR D7PHZ2 , VRTA_PENAE , T; K3VA96 , W4931_FUSPC, T;
DR Q03149 , WA_EMENI , T; G3Y419 , YANA_ASPNA , T;
DR A0A098D6U0, ZEA1_GIBZE , T; A0A098D8A0, ZEA2_GIBZE , T;
DR P08757 , FAS_CAPHI , P; P07855 , FAS_RABIT , P;
DR Q9HYV7 , BEKAS_PSEAE, N; P63455 , KASA_MYCBO , N;
DR Q9CBS7 , KASA_MYCLE , N; H8ESN0 , KASA_MYCTE , N;
DR P9WQD8 , KASA_MYCTO , N; P9WQD9 , KASA_MYCTU , N;
DR P63457 , KASB_MYCBO , N; O69473 , KASB_MYCLE , N;
DR P9WQD6 , KASB_MYCTO , N; P9WQD7 , KASB_MYCTU , N;
DR Q2TXF0 , ORYA_ASPOR , N; Q5W262 , PIGJ_SERS3 , N;
DR Q54IX3 , PKS26_DICDI, N; Q54B49 , PKS45_DICDI, N;
DR Q7VM49 , GLPB_HAEDU , F; Q1DDB3 , KDSB_MYXXD , F;
DR A1SRP8 , MDH_PSYIN , F; Q2N6I8 , MNMG_ERYLH , F;
DR Q3SZM5 , NEUA_BOVIN , F; Q8NFW8 , NEUA_HUMAN , F;
DR Q5R6R5 , NEUA_PONAB , F; Q0DST9 , PUS5_ORYSJ , F;
DR O04086 , Y1105_ARATH, F;
3D 1B3N; 1DD8; 1E5M; 1FJ4; 1FJ8; 1G5X; 1H4F; 1KAS; 1TQY; 1W0I; 2AQ7; 2AQB;
3D 2BUH; 2BUI; 2BYW; 2BYX; 2BYY; 2BYZ; 2BZ3; 2BZ4; 2C9H; 2CDH; 2GFW; 2GFY;
3D 2GQD; 2HG4; 2IWY; 2IWZ; 2IX4; 2PFF; 2QO3; 2UV8; 2VB7; 2VB8; 2VB9; 2VBA;
3D 2VKZ; 3HHD; 3HMJ; 4JRH; 4JRM; 4LS5; 4LS6; 4LS7; 4LS8; 4NA1; 5BP1; 5KOF;
3D 5MY0; 5MY2; 6C9U; 6FIJ; 6FIK; 6JSH; 6JSI; 6KOG; 6OKC; 6OKF; 6OKG; 6OLT;
3D 6QL5; 6QL6; 6QL7; 6QL9; 6ROP; 6TA1; 6U5V; 6U5W; 6WC7; 7CPX; 7CPY; 7L4E;
3D 7L4L; 7M7E; 7M7F; 7M7G; 7M7H;
PR PRU10022;
DO PDOC00529;
//
