KEGG   Panthera tigris altaica (Amur tiger): 102951241
Entry
102951241         CDS       T02988                                 

Gene name
HIF1A
Definition
(RefSeq) hypoxia inducible factor 1 alpha subunit
  KO
K08268  hypoxia-inducible factor 1 alpha
Organism
ptg  Panthera tigris altaica (Amur tiger)
Pathway
ptg04066  HIF-1 signaling pathway
ptg04137  Mitophagy - animal
ptg04140  Autophagy - animal
ptg04659  Th17 cell differentiation
ptg04919  Thyroid hormone signaling pathway
ptg05167  Kaposi sarcoma-associated herpesvirus infection
ptg05200  Pathways in cancer
ptg05205  Proteoglycans in cancer
ptg05211  Renal cell carcinoma
ptg05230  Central carbon metabolism in cancer
ptg05231  Choline metabolism in cancer
ptg05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
Brite
KEGG Orthology (KO) [BR:ptg00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04066 HIF-1 signaling pathway
    102951241 (HIF1A)
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    102951241 (HIF1A)
   04137 Mitophagy - animal
    102951241 (HIF1A)
 09150 Organismal Systems
  09151 Immune system
   04659 Th17 cell differentiation
    102951241 (HIF1A)
  09152 Endocrine system
   04919 Thyroid hormone signaling pathway
    102951241 (HIF1A)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    102951241 (HIF1A)
   05205 Proteoglycans in cancer
    102951241 (HIF1A)
   05230 Central carbon metabolism in cancer
    102951241 (HIF1A)
   05231 Choline metabolism in cancer
    102951241 (HIF1A)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    102951241 (HIF1A)
  09162 Cancer: specific types
   05211 Renal cell carcinoma
    102951241 (HIF1A)
  09172 Infectious disease: viral
   05167 Kaposi sarcoma-associated herpesvirus infection
    102951241 (HIF1A)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors [BR:ptg03000]
    102951241 (HIF1A)
Transcription factors [BR:ptg03000]
 Eukaryotic type
  Basic helix-loop-helix (bHLH)
   Factors with PAS domain
    102951241 (HIF1A)
SSDB
Motif
Pfam: PAS_3 HIF-1a_CTAD PAS_11 HIF-1 PAS PAS_9 PAS_4 HLH
Other DBs
NCBI-GeneID: 102951241
NCBI-ProteinID: XP_015398790
Position
Un
AA seq 940 aa
MINSLCTPEKALIKFKKISSERRKEKSRDAARSRRSKESEVFYELAHQLPLPHNVSSHLD
KASVMRLTISYLRVRKLLDAGDLDIEDEMKAQMNCFYLKALDGFVMVLTDDGDMIYISDN
VNKYMGLTQFELTGHSVFDFTHPCDHEEMREMLTHRNGLVKKGKEQNTQRSFFLRMKCTL
TSRGRTMNIKSATWKVLHCTGHIHVYDTNSNQSQCGYKKPPMTCLVLICEPIPHPSNIEI
PLDSKTFLSRHSLDMKFSYCDERITELMGYEPEELLGRSIYEYYHALDSDHLTKTHHDMF
TKGQVTTGQYRMLAKRGGYVWVETQATVIYNTKNSQPQCIVCVNYVVSGIIQHDLIFSLQ
QTECVLKPVESSDMKMTQLFTKVESEDTSSLFDKLKKEPDALTLLAPAAGDTIISLDFGS
NDTETDDQQLEEVPLYNDVMLPSSNEKLQNINLAMSPLPASETPKPLRSSADPALNQEVV
LKLEPNPESLELSFTMPQIQDQPASPSDGSTRQSSPEPTSPSEYCFDVDSDMVNEFKLEL
VEKLFAEDTEAKNPFSTQDTDLDLEMLAPYIPMDDDFQLRSFDQLSPLESSSTSPQSVGT
ITVFQPAQMQEEPPVTTTSTTATTDELKTVTKDGIEDIKILIASPSPTHVPKVTTGATTS
LYGDTGSRTASPNRAGKGVIEQTEKSHPRSPNVLSVTLSQRTTIPEEELNPKILALQNAQ
RKRKIEHDGSLFQAVGIGTLLQQPDDRATTTSLSWKRVKGCKSSEQNGMEQKTIILIPSD
LACRLLGQSMDESGLPQLTSYDCEVNAPVQGSRNLLQGEELLRALDQWSGYVMTGSQKMT
CKSSDLEEKATLTDSRTGRKGLDIIFLPVVDGFIQDAAQTPDLLVLFNFLYSLVSDPSRD
GEERQVPESSSDQTAPSAGKITRMRRGPTTPNVRGAAGAT
NT seq 2823 nt   +upstreamnt  +downstreamnt
atgataaattctctttgtacaccagagaaagcccttataaaattcaaaaagataagttct
gaacgtcgaaaagaaaagtctagagatgcagcgagatctcggcgaagtaaagagtctgaa
gttttctatgaacttgctcatcagttgccacttccccataatgtgagctcgcatctcgat
aaggcttctgttatgaggctcaccatcagctatttgcgtgtgaggaaacttctggatgct
ggtgatttagatattgaagatgaaatgaaggcacagatgaattgcttttatttgaaagcc
ttggatggttttgttatggttctcacagatgatggtgacatgatctacatttctgataat
gtgaacaagtacatgggattaactcagtttgaactaactggacacagtgtgtttgatttt
actcatccatgtgaccatgaagaaatgagagaaatgcttacacatagaaatggccttgtg
aagaagggtaaagagcagaatacacagcgaagcttttttctcagaatgaagtgtacccta
actagccgagggagaaccatgaacataaagtcagcaacgtggaaagtacttcactgcaca
ggccatattcatgtctacgataccaatagtaaccaatctcagtgtgggtataagaaacca
cccatgacgtgcttggtgctgatttgtgaacccattcctcatccatcaaatattgaaatt
cctttagatagcaagacttttctgagtcgtcatagtctggatatgaaattttcttactgt
gatgaaagaattactgaattgatgggatatgagccagaggaacttttgggccggtcaata
tatgaatattaccacgctttggactctgaccatctgaccaaaactcatcatgacatgttt
actaaaggccaagtcaccacaggacagtacaggatgcttgccaaaagaggtggatatgtc
tgggttgaaactcaagcgaccgtcatatataacactaagaactctcaaccacagtgcatt
gtatgtgtaaattacgttgtgagtggtattattcagcacgacttgattttctcccttcaa
caaacagaatgtgtcctcaaaccagttgaatcttcagatatgaaaatgactcagctgttc
accaaagttgaatcagaagacacaagtagtctgtttgataaacttaagaaggaacctgat
gctttaactttgctggccccagctgctggagacacaatcatatctttagatttcggcagc
aatgacacagaaactgatgaccagcaacttgaggaagttccattgtataatgatgtaatg
cttccctcatccaatgaaaaattacagaacataaatttggcaatgtctccattacctgct
tctgaaactccaaagccacttcgaagtagtgctgaccctgcactcaatcaagaagttgta
ctaaaattagagccaaatccagagtcactggaactttcttttactatgccccagattcaa
gatcagccagctagtccttctgatggaagcactagacagagttcacctgagcctaccagt
cccagtgaatattgttttgatgtggatagtgatatggtcaatgaatttaagctggaattg
gtagagaaactttttgctgaagacacagaagccaagaatccattttccacccaggacacg
gatttagacttggagatgttagctccttacatcccaatggatgatgacttccagttacgt
tcctttgatcagttgtcgccactggaaagcagttctacaagccctcaaagcgtgggcaca
attacagtattccagccggctcagatgcaggaggaacctcctgttaccactaccagtacc
actgccaccactgatgaattaaaaacagtgacaaaagatggtatagaagacattaaaata
ctgattgcatctccatctcctacccatgtacccaaagtaactactggtgccacaacatca
ctgtatggtgatactggaagtcggacagcctcaccaaacagagcaggaaaaggagtcata
gaacagacagaaaaatctcatccaagaagccctaatgtgttatctgtcactttgagtcaa
agaactaccattcctgaagaagaactaaatccaaagatactagctttgcagaatgctcag
agaaagcgaaaaatagaacatgacggttcactttttcaagcagtaggaattggaacatta
ttacagcagccagatgatcgtgcaactactacatcactttcttggaaacgcgtaaaagga
tgcaaatctagtgagcagaatggaatggagcaaaagacaattattttaataccctctgat
ttagcatgtagactgctggggcaatcaatggatgagagtggattaccacaactgaccagt
tatgattgtgaagttaatgctcctgtacaaggcagcagaaacctactgcagggtgaagaa
ttactcagagctttggatcaatggtcaggttatgtaatgaccgggagtcagaaaatgact
tgtaagagcagtgatttagaagagaaagccactttaacagacagtagaactggaagaaaa
ggtttggacataattttcttacctgtagtggacggttttatccaagacgctgcccagaca
cccgatctcctcgtactatttaatttcctttattcccttgtctcggatccatcccgggac
ggagaggaaagacaggtgcctgagagcagcagtgatcagacagccccctcagcggggaaa
ataacaaggatgcggaggggaccgaccacccctaatgtccgtggtgccgctggtgctaca
tga

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