KEGG   Panthera tigris altaica (Amur tiger): 102952769
Entry
102952769         CDS       T02988                                 
Symbol
FOS
Name
(RefSeq) Fos proto-oncogene, AP-1 transcription factor subunit
  KO
K04379  proto-oncogene protein c-fos
Organism
ptg  Panthera tigris altaica (Amur tiger)
Pathway
ptg01522  Endocrine resistance
ptg04010  MAPK signaling pathway
ptg04024  cAMP signaling pathway
ptg04210  Apoptosis
ptg04380  Osteoclast differentiation
ptg04620  Toll-like receptor signaling pathway
ptg04657  IL-17 signaling pathway
ptg04658  Th1 and Th2 cell differentiation
ptg04659  Th17 cell differentiation
ptg04660  T cell receptor signaling pathway
ptg04662  B cell receptor signaling pathway
ptg04668  TNF signaling pathway
ptg04713  Circadian entrainment
ptg04725  Cholinergic synapse
ptg04728  Dopaminergic synapse
ptg04915  Estrogen signaling pathway
ptg04917  Prolactin signaling pathway
ptg04921  Oxytocin signaling pathway
ptg04926  Relaxin signaling pathway
ptg04928  Parathyroid hormone synthesis, secretion and action
ptg04932  Non-alcoholic fatty liver disease
ptg04935  Growth hormone synthesis, secretion and action
ptg05031  Amphetamine addiction
ptg05132  Salmonella infection
ptg05133  Pertussis
ptg05135  Yersinia infection
ptg05140  Leishmaniasis
ptg05142  Chagas disease
ptg05161  Hepatitis B
ptg05162  Measles
ptg05166  Human T-cell leukemia virus 1 infection
ptg05167  Kaposi sarcoma-associated herpesvirus infection
ptg05170  Human immunodeficiency virus 1 infection
ptg05171  Coronavirus disease - COVID-19
ptg05200  Pathways in cancer
ptg05207  Chemical carcinogenesis - receptor activation
ptg05208  Chemical carcinogenesis - reactive oxygen species
ptg05210  Colorectal cancer
ptg05224  Breast cancer
ptg05231  Choline metabolism in cancer
ptg05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
ptg05323  Rheumatoid arthritis
ptg05417  Lipid and atherosclerosis
ptg05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:ptg00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    102952769 (FOS)
   04668 TNF signaling pathway
    102952769 (FOS)
   04024 cAMP signaling pathway
    102952769 (FOS)
 09140 Cellular Processes
  09143 Cell growth and death
   04210 Apoptosis
    102952769 (FOS)
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    102952769 (FOS)
   04660 T cell receptor signaling pathway
    102952769 (FOS)
   04658 Th1 and Th2 cell differentiation
    102952769 (FOS)
   04659 Th17 cell differentiation
    102952769 (FOS)
   04657 IL-17 signaling pathway
    102952769 (FOS)
   04662 B cell receptor signaling pathway
    102952769 (FOS)
  09152 Endocrine system
   04915 Estrogen signaling pathway
    102952769 (FOS)
   04917 Prolactin signaling pathway
    102952769 (FOS)
   04921 Oxytocin signaling pathway
    102952769 (FOS)
   04926 Relaxin signaling pathway
    102952769 (FOS)
   04935 Growth hormone synthesis, secretion and action
    102952769 (FOS)
   04928 Parathyroid hormone synthesis, secretion and action
    102952769 (FOS)
  09156 Nervous system
   04725 Cholinergic synapse
    102952769 (FOS)
   04728 Dopaminergic synapse
    102952769 (FOS)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    102952769 (FOS)
  09159 Environmental adaptation
   04713 Circadian entrainment
    102952769 (FOS)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    102952769 (FOS)
   05207 Chemical carcinogenesis - receptor activation
    102952769 (FOS)
   05208 Chemical carcinogenesis - reactive oxygen species
    102952769 (FOS)
   05231 Choline metabolism in cancer
    102952769 (FOS)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    102952769 (FOS)
  09162 Cancer: specific types
   05210 Colorectal cancer
    102952769 (FOS)
   05224 Breast cancer
    102952769 (FOS)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    102952769 (FOS)
   05170 Human immunodeficiency virus 1 infection
    102952769 (FOS)
   05161 Hepatitis B
    102952769 (FOS)
   05171 Coronavirus disease - COVID-19
    102952769 (FOS)
   05162 Measles
    102952769 (FOS)
   05167 Kaposi sarcoma-associated herpesvirus infection
    102952769 (FOS)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    102952769 (FOS)
   05135 Yersinia infection
    102952769 (FOS)
   05133 Pertussis
    102952769 (FOS)
  09174 Infectious disease: parasitic
   05140 Leishmaniasis
    102952769 (FOS)
   05142 Chagas disease
    102952769 (FOS)
  09163 Immune disease
   05323 Rheumatoid arthritis
    102952769 (FOS)
  09165 Substance dependence
   05031 Amphetamine addiction
    102952769 (FOS)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    102952769 (FOS)
   05418 Fluid shear stress and atherosclerosis
    102952769 (FOS)
  09167 Endocrine and metabolic disease
   04932 Non-alcoholic fatty liver disease
    102952769 (FOS)
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    102952769 (FOS)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors [BR:ptg03000]
    102952769 (FOS)
   04131 Membrane trafficking [BR:ptg04131]
    102952769 (FOS)
Transcription factors [BR:ptg03000]
 Eukaryotic type
  Basic leucine zipper (bZIP)
   AP-1(-like) components, Fos
    102952769 (FOS)
Membrane trafficking [BR:ptg04131]
 Autophagy
  Chaperone mediated autophagy (CMA)
   Selective cargos
    102952769 (FOS)
SSDB
Motif
Pfam: bZIP_1 bZIP_2 bZIP_Maf MIC19_MIC25 DUF3450 HALZ Macoilin
Other DBs
NCBI-GeneID: 102952769
NCBI-ProteinID: XP_007095105
UniProt: A0A8C9KEH0
Position
Un
AA seq 381 aa
MMFSGFNADYEASSSRCSSASPAGDNLSYYHSPADSFSSMGSPVNAQDFCTDLAVSSANF
IPTVTAISTSPDLQWLVQPTLVSSVAPSQTRAPHPYGVPAPSAGAYSRAGVVKTVTAGGR
AQSIGRRGKVEQLSPEEEEKRRIRRERNKMAAAKCRNRRRELTDTLQAETDQLEDEKSAL
QTEIANLLKEKEKLEFILAAHRPACKIPDDLGFPEEMSVASLDLSGGLPEAATPESEEAF
TLPLLNDPEPKPSVEPVKSISSMELKAEPFDDFLFPASSRPSGSETARSVPDMDLSGSFY
AADWEPLHGGSLGMGPMATELEPLCTPVVTCTPSCTTYTSSFVFTYPEADSFPSCGAAHR
KGSSSNEPSSDSLSSPTLLAL
NT seq 1146 nt   +upstreamnt  +downstreamnt
atgatgttctctggcttcaacgccgactacgaggcgtcctcctcccgctgcagcagcgcc
tccccggccggggacaatctctcctactaccactcaccggccgactccttctccagcatg
ggctctcctgtcaatgcgcaggacttctgcacggatctggccgtctccagcgccaacttt
atcccaacggtgactgccatctccaccagcccggacctgcagtggctggtgcagcccacc
ctggtctcctccgtggctccttctcagaccagagccccccacccctatggagtccccgcc
ccctccgccggggcttactccagggctggagtcgtgaagaccgtgaccgcaggaggccga
gctcagagcattggcaggaggggcaaagtggaacagttgtccccagaagaagaagagaaa
aggagaatccgaagggaaaggaataagatggctgcagccaagtgccggaaccggaggcgg
gagctcacggatacgctgcaagcggagacagaccaactagaagatgagaagtctgctttg
cagactgagattgccaacctgctgaaggagaaggaaaaactagagttcatcctggcagct
caccgacccgcctgcaagatccccgatgacctgggcttcccggaagagatgtctgtggct
tccctagatctgagcgggggcctgccggaagctgccacccccgagtcggaggaggctttc
accctgcccctcctcaatgatcctgagcccaagccctccgtggagccggtcaagagcatc
agcagcatggagctgaaggccgagccctttgatgacttcctgttcccagcatcgtccagg
cccagcggctctgagaccgcccgctctgtgccagacatggacctgtctggttccttctat
gcagcagactgggagcccctgcatggtggctccctggggatggggcccatggccacagag
ctggagcctctgtgcaccccggtggtcacctgtactcctagctgcactacttacacgtct
tccttcgtcttcacctaccctgaggctgactccttccccagctgtggggctgctcaccgc
aagggcagcagcagcaacgaaccctcctctgactcgctcagctcacccacgctgctggcc
ctgtga

DBGET integrated database retrieval system