KEGG   Panthera tigris altaica (Amur tiger): 102965436
Entry
102965436         CDS       T02988                                 
Symbol
GCK
Name
(RefSeq) glucokinase
  KO
K12407  glucokinase [EC:2.7.1.2]
Organism
ptg  Panthera tigris altaica (Amur tiger)
Pathway
ptg00010  Glycolysis / Gluconeogenesis
ptg00052  Galactose metabolism
ptg00500  Starch and sucrose metabolism
ptg00520  Amino sugar and nucleotide sugar metabolism
ptg00524  Neomycin, kanamycin and gentamicin biosynthesis
ptg01100  Metabolic pathways
ptg01200  Carbon metabolism
ptg01250  Biosynthesis of nucleotide sugars
ptg04910  Insulin signaling pathway
ptg04911  Insulin secretion
ptg04917  Prolactin signaling pathway
ptg04922  Glucagon signaling pathway
ptg04930  Type II diabetes mellitus
ptg04950  Maturity onset diabetes of the young
ptg05230  Central carbon metabolism in cancer
Module
ptg_M00001  Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate
ptg_M00549  Nucleotide sugar biosynthesis, glucose => UDP-glucose
ptg_M00892  UDP-N-acetyl-D-glucosamine biosynthesis, eukaryotes, glucose => UDP-GlcNAc
Brite
KEGG Orthology (KO) [BR:ptg00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00010 Glycolysis / Gluconeogenesis
    102965436 (GCK)
   00052 Galactose metabolism
    102965436 (GCK)
   00500 Starch and sucrose metabolism
    102965436 (GCK)
   00520 Amino sugar and nucleotide sugar metabolism
    102965436 (GCK)
  09110 Biosynthesis of other secondary metabolites
   00524 Neomycin, kanamycin and gentamicin biosynthesis
    102965436 (GCK)
 09150 Organismal Systems
  09152 Endocrine system
   04911 Insulin secretion
    102965436 (GCK)
   04910 Insulin signaling pathway
    102965436 (GCK)
   04922 Glucagon signaling pathway
    102965436 (GCK)
   04917 Prolactin signaling pathway
    102965436 (GCK)
 09160 Human Diseases
  09161 Cancer: overview
   05230 Central carbon metabolism in cancer
    102965436 (GCK)
  09167 Endocrine and metabolic disease
   04930 Type II diabetes mellitus
    102965436 (GCK)
   04950 Maturity onset diabetes of the young
    102965436 (GCK)
Enzymes [BR:ptg01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.1  Phosphotransferases with an alcohol group as acceptor
    2.7.1.2  glucokinase
     102965436 (GCK)
SSDB
Motif
Pfam: Hexokinase_1 Hexokinase_2
Other DBs
NCBI-GeneID: 102965436
NCBI-ProteinID: XP_015392062
Position
Un
AA seq 331 aa
MGSAEQTSGGAVPLEGGIWAKRQLCLSLALSLPILTPMVQTRQEGSLEYLLLCQQAETTE
KDPQCQSQAYHEDQKNQLDMPPSRRALGKVGDFLSLDLGGTNFRVMLVKVGEGEEGQWSV
KTKHQMYSIPEDAMTGTAEMLFDYISECISDFLDKHQMKHKKLPLGFTFSFPVRHEDIDK
GILLNWTKGFKASGAEGNNIVGLLRDAIKRRGDFEMDVVAMVNDTVATMISCYYEDRRCE
VGMIVGTGCNACYMEEMHNVELVEGEEGRMCVNTEWGAFGDSGELDEFLLEYDRVVDENS
LNPGQQLMHSSGRGAALVSAVACKKACMLGQ
NT seq 996 nt   +upstreamnt  +downstreamnt
atgggttcagccgagcagacgtcaggtggtgctgtgcccctggaaggaggcatctgggcc
aagaggcagctgtgcctgtcactggccctgtcactgcctatcctgacacccatggtgcag
actcgccaggaggggtctctagagtacttgctcctgtgccagcaggctgagaccactgaa
aaggatccccagtgccagtcccaggcctaccatgaggaccagaagaaccagttggacatg
cccccgagtcggagagcactgggcaaagttggggacttcctctccctggacctgggcggc
accaacttcagggtgatgctggtgaaggtgggggagggcgaagaggggcagtggagcgtg
aagaccaagcaccagatgtattccatccccgaggacgccatgacgggtactgctgagatg
ctctttgactacatctctgagtgcatctccgacttcctggacaagcaccagatgaagcac
aagaagctgcccttgggcttcaccttctccttccccgtgaggcatgaggacatcgacaag
ggcatcctcctcaattggaccaagggcttcaaggcctcaggagcagaagggaacaacatc
gttgggctcctacgtgatgccatcaaacggagaggggactttgaaatggacgtggtggcg
atggtgaatgacactgtggccacgatgatctcctgctactatgaagaccgccggtgtgag
gttggcatgattgtgggaacaggctgcaatgcctgctacatggaggagatgcacaacgtg
gagctggtggaaggggaggagggccgcatgtgcgtcaacaccgagtggggcgccttcggg
gactccggagagctggacgagttcctgctggagtatgaccgcgtggtggacgagaactcc
ctgaaccctgggcagcagctgatgcacagcagcggccgaggcgccgccctggtgtccgcg
gtggcctgtaagaaggcctgcatgctgggccagtga

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (18)   
   KEGG PATHWAY (15)   
   KEGG MODULE (3)   
Chemical substance (8)   
   KEGG COMPOUND (8)   
Chemical reaction (4)   
   KEGG ENZYME (1)   
   KEGG REACTION (3)   
Genome (1)   
   KEGG GENOME (1)   
Gene (4)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   OC (1)   
Protein sequence (2)   
   RefSeq(pep) (2)   
DNA sequence (2)   
   RefSeq(nuc) (2)   
Protein domain (2)   
   Pfam (2)   
All databases (43)   

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