KEGG   Panthera tigris altaica (Amur tiger): 102970886
Entry
102970886         CDS       T02988                                 
Symbol
KALRN
Name
(RefSeq) kalirin, RhoGEF kinase
  KO
K15048  kalirin [EC:2.7.11.1]
Organism
ptg  Panthera tigris altaica (Amur tiger)
Brite
KEGG Orthology (KO) [BR:ptg00001]
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:ptg01001]
    102970886 (KALRN)
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:ptg04131]
    102970886 (KALRN)
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:ptg04147]
    102970886 (KALRN)
Enzymes [BR:ptg01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.1  non-specific serine/threonine protein kinase
     102970886 (KALRN)
Protein kinases [BR:ptg01001]
 Serine/threonine kinases: CAMK group
  Trio family [OT]
   102970886 (KALRN)
Membrane trafficking [BR:ptg04131]
 Others
  Rho GTPase associated proteins
   Rho guanine nucleotide exchange factors (GEFs)
    102970886 (KALRN)
Exosome [BR:ptg04147]
 Exosomal proteins
  Exosomal proteins of other body fluids (saliva and urine)
   102970886 (KALRN)
SSDB
Motif
Pfam: RhoGEF Pkinase Spectrin SH3-RhoG_link PK_Tyr_Ser-Thr I-set Ig_3 PH fn3 ig SH3_1 IQ_SEC7_PH SH3_2 PH_10 Ig_2 PH_19 SH3_9 PH_13 V-set Pur_ac_phosph_N RL11D T4_Rnl2_C Tissue_fac Herpes_gE_N
Other DBs
NCBI-GeneID: 102970886
NCBI-ProteinID: XP_015400283
Position
Un
AA seq 2875 aa
MRGSKWDLIKPLLKTLQEAFPAEIHVALIIKPDNFWQKQKTNFGSSKFIFETSMVSVEGL
TKLVDPSQLTEEFDGSLDYNHEEWIELRLSLEEFFNSAVHLLSRLEDLQEMLARKEFPVD
VEGSRRLIDEHTQLKKKVLKAPVEELDREGQRLLQCIRCSDGFSGRNCIPGSADFQSLVP
KITSLLDKLHSTRQHLHQMWHVRKLKLDQCFQLRLFEQDAEKMFDWISHNKELFLQSHTE
IGVSYQHALDLQTQHNHFAMNSMNAYVNINRIMSVASRLSEAGHYASQQIKQISTQLDQE
WKSFAAALDERSTILAMSAVFHQKAEQFLSGVDAWCKMCSEGGLPSEMQDLELAIHHHQS
LYEQVTQAYTEVSQDGKALLDVLQRPLSPGNSESLTATANYSKAVHQVLDVVHEVLHHQR
RLESIWQHRKVRLHQRLQLCVFQQDVQQVLDWIENHGEAFLSKHTGVGKSLHRARALQKR
HDDFEEVAQNTYTNADKLLEAAEQLAQTGECDPEEIYKAARHLEVRIQDFVRRVEQRKLL
LDMSVSFHTHTKELWTWMEDLQKEMLEDVCADSVDAVQELIKQFQQQQTATLDATLNVIK
EGEDLIQQLRDSAVSNNKTPHSSSISHIESVLQQLDDAQVQMEELFHERKIKLDIFLQLR
IFEQYTIEVTAELDAWNEDLLRQMNDFNTEDLTLAEQRLQRHTERKLAMNNMTFEVIQQG
QDLHQYIMEVQASGIELICEKDIDLAAQVQELLEFLHEKQHELELNAEQTHKRLEQCLQL
RHLQAEVKQVLGWIRNGESMLNASLVNASSLSEAEQLQREHEQFQLAIESLFHATSLQKT
HQSALQVQQKAEALLQAGHYDADAIRECAEKVALHWQQLMLKMEDRLKLVNASVAFYKTS
EQVCSVLESLEQEYRRDEDWCGGRDKLGPAAEMDHVIPLISKHLEQKEAFLKACTLARRN
AEVFLKYIHRNNVSMPSAASHTRGPEQQVKAILSELLQRENRVLHFWTLKKRRLDQCQQY
VVFERSAKQALDWIQETGEYYLSTHTSPGETTEETQELLKEYGEFRVPAKQTKEKVKLLI
QLADSFVEKGHIHATEIRKWVTTVDKHYRDFSLRMGKYRYSLEKALGVNTEDNKDLELDI
IPASLSDREVKLRDANHEVNEEKRKSARKKEFIMAELLQTEKAYVRDLHECLETYLWEMT
SGVEEIPPGILNKEHIIFGNIQEIYDFHNNIFLKELEKYEQLPEDVGHCFVTWADKFQMY
VTYCKNKPDSNQLILEHAGTFFDEIQQRHGLANSISSYLIKPVQRITKYQLLLKELLTCC
EEGKGELKDGLEVMLSVPKKANDAMHVSMLEGFDENLDVQGELILQDAFQVWDPKSLIRK
GRERHLFLFEISLVFSKEIKDSSGHTKYVYKNKLLTSELGVTEHVEGDPCKFALWSGRTP
SSDNKTVLKASNIETKQEWIKNIREVIQERIIHLKGALKEPIQLPKTPAKQRNNSKRDGV
EDVDSQGDGSSQPDTISIASRTSQNTVDSDKLSGGCELTVVLQDFNAGHSSELTIQVGQT
VELLERPSERPGWCLVRTTERSPPQEGLVPSSALCISHSRSSVEMDCFFPLVKDAYSHSS
SENGGKSESVANLQSQPSLNSIHSSPGPKRSTNTLKKWLTSPVRRLNSGKADGNIKKQKK
VRDGRKSFDLGSPKPGDETTPQGDSADEKNKKGWGEDEPDEESHTPLPPPMKIFDNDPTQ
DEMSSSLLAARQASTEVPSAADLVSAIEQLVKSKLSLEGGSYRGSLKDPVGCLNEGMTPP
TPPRNLEEEQKAKALRGRMFVLNELVQTEKDYVKDLGIVVEGFMKRIEEKGVPEDMRGKD
KIVFGNIHQIYDWHKDFFLAELEKCIQEQDRLGQLFIKHERKLHIYVWYCQNKPRSEYIV
AEYDAYFEEVKQEINQRLTLSDFLIKPIQRITKYQLLLKDFLRYSEKAGLECSDIEKAVE
LMCLVPKRCNDMMNLGRLQGFEGTLTAQGKLLQQDTFYVIELDAGMQSRTKERRVFLFEQ
IVIFSELLRKGSLTPGYMFKRSIKMNYLVLEENVDNDPCKFALMNRETSERVILQAANAD
IQQAWVQDINQVLETQRDFLNALQSPIEYQRKERNTAVMRSQPSRVPQASPRPYSSVPGG
SDKPPKGSSYNPPLPPLKISTSNGSPGFDYHQPGEKFEATKQGDLGGCNGTSSMAVIKDY
YALKENEICVSQGEVVQVLAVNQQNMCLVYQPASDCSPAAEGWVPGSVLAPLTKATAAAE
SSDGSIKKSCSWHTLRMRKRAEVENTGKNEATGPRKPKDILGNKVSVKETNSSEESECDD
LDPNTSMEILNPNFIQEVAPEFLVPLVDVTCLLGDTVTLQCKVCGRPKPTITWKGPDQNI
LDTDNSSATYTVSSCDSGEITLKICNLMPQDSGIYTCIATNDHGTTSTSATVKVQGVPAA
PNRPIAQERSCTSVILRWLPPSSTGNCTISGYTVEYREEGSQAWQQSVASTLDTYLVIED
LSPGSPYQFRVSASNPWGISLPSEPSEFVRLPEYDAAADGATISWKDNFDSAYTELNEIG
RGRFSIVKKCIHKATRKDVAVKFVSKKMKKKEQAAHEAALLQHLQHPQYITLHDTYESPT
SYILILELMDDGRLLDYLMHHDELMEEKVAFYIRDIIEALQYLHNCRVAHLDIKPENLLI
DLRIPVPRVKLIDLEDAVQISGHFHIHHLLGNPEFAAPEVIQGIPVSLGTDIWSIGVLTY
VMLSGVSPFLDESKEETCINVCRVDFSFPHEYFCGVSNAARDFINVILQEDFRRRPTAAT
CLQHPWLQPHNGSYSKIPLDTSRLACFIERRKHQNDVRPIPNVKSYIVNRVNQGT
NT seq 8628 nt   +upstreamnt  +downstreamnt
atgcggggctccaagtgggacctcatcaagcccctcctcaagacgctacaggaagccttt
ccagctgagatccatgtggccctcatcatcaaacccgacaacttctggcagaaacagaag
accaactttggcagctccaaattcatctttgagacaagcatggtgtccgtggagggcctc
acgaaactggtggacccctcccagctgaccgaggagtttgatggctccctggactacaac
cacgaagagtggatcgagctgcggctctccctggaggagttcttcaacagtgctgtgcac
ctgctctcacgcctcgaggacctacaggagatgctggcccggaaggagttccccgtggac
gtggaaggctcacggcgcctcatcgacgagcacacgcagctcaagaagaaggtgctgaag
gcccctgtggaagagctggaccgggaggggcagcggctgctgcagtgtatccgctgcagt
gatggcttctcagggcgcaactgcatcccgggtagcgccgacttccagagcctggtgccc
aagatcaccagcctcctggacaagctgcactccacccggcagcacctgcaccagatgtgg
catgtgcgcaagctcaagttggaccagtgcttccagctacggctttttgagcaggatgcc
gagaagatgttcgactggataagccacaacaaggagttattcctccagagccatacggag
atcggcgtgagctaccagcatgctctagacctccagacacagcacaatcactttgccatg
aactccatgaatgcttatgtcaatatcaaccgcatcatgtccgtggcttcccgcctctct
gaggccggccattacgcctcacagcaaatcaagcagatttccacacagctggaccaggag
tggaagagcttcgctgctgctctggatgaacgcagcaccatccttgccatgtctgcggta
ttccaccagaaggctgagcagttcctgtcaggagtggacgcctggtgcaagatgtgcagt
gagggtggcctgccatccgagatgcaggacctggagctggcaatccaccatcatcagtcc
ttgtatgagcaggtgacccaggcctacacggaggtcagccaagatggcaaagcactgctg
gatgtgctgcagcgtcccctgagtcctgggaactctgagtccctcacggccactgccaac
tactccaaggcggtgcaccaggtgctggacgtggtgcacgaggtgctgcaccaccagcgg
cggctcgagagcatctggcagcaccgcaaggtgcggctccaccagcggctgcagctctgt
gtattccagcaagacgtgcaacaggtgttggattggattgaaaaccatggtgaggccttt
ctcagcaaacacaccggggttgggaagtccctgcatcgagcccgggccctgcagaagagg
catgatgactttgaagaggtggctcagaatacctacaccaacgcggacaagctcctagag
gctgcagagcagctggctcagacgggggaatgtgaccccgaggagatctacaaggcagct
cgacacctggaggtgcgcatccaggactttgtgcgcagggtggaacagcggaagcttctc
ctggacatgtctgtctccttccacacgcacaccaaagagttgtggacatggatggaagac
cttcagaaggagatgctggaggacgtctgtgcagactcagtggatgcggtccaggaactg
atcaagcagttccagcagcagcagactgccactctggacgccacgctcaatgtcatcaag
gaaggcgaagaccttatccagcagctcagggactcggctgtgtccaacaacaagacaccc
cacagcagctccatcagccacatcgagtcagtccttcagcagctggatgatgcccaggta
cagatggaggagctgttccacgagcggaagatcaagctagacatcttcctgcagctgcgc
atcttcgagcaatataccattgaggtgacagcagagctagacgcctggaatgaagacttg
ctccggcagatgaatgacttcaatacagaggatctgacgctcgcggagcagcggctgcaa
cgccacacagagcggaagctggccatgaacaacatgaccttcgaggtcatccagcagggt
caggatctgcaccagtacatcatggaggtccaggcctcaggaatcgagttaatctgtgag
aaagacatcgatctggcagcccaggtacaagagctactggagtttctccatgagaagcag
cacgaactggagctcaacgcagagcagacccataagcggttagagcagtgcctccagctg
cggcacctgcaggccgaggtcaaacaggtcctgggatggatccgcaatggggagtcaatg
cttaatgccagcctggtcaatgccagctctttgtctgaagcagagcagctgcagagggaa
cacgagcagttccaactggcaatcgagtccctctttcatgccacttccttgcagaagacg
caccagagcgccctgcaggtacagcagaaagctgaggctctgctccaggccggccactat
gatgccgatgccatccgggaatgtgccgagaaggtggccctccactggcagcagctcatg
ctgaagatggaagaccggctaaaactagtcaatgcctctgtggcattttataaaacttct
gaacaggtctgtagtgtcctagagagtttagagcaagaataccggagagatgaggactgg
tgtggtggacgagacaaactgggaccagcagcagagatggaccacgtcatcccactcatc
agtaaacatttggaacaaaaggaggcctttcttaaggcctgtaccctggcgcggcggaac
gctgaagtgtttctcaagtacatccacaggaacaacgtcagcatgcccagtgccgccagc
cacacgcggggacctgagcagcaagtgaaagccatcttgagtgagctcttacagagggag
aatcgcgtcctgcacttctggaccttgaagaagcgacggttagaccagtgccagcaatat
gtggtgtttgaacgcagtgctaagcaggcgctggactggatccaagaaacaggtgaatat
tacctctcaacacatacctcccccggagagaccacagaggagactcaggaactgctgaaa
gagtatggggaattcagggtgcccgccaagcaaacaaaggagaaggtgaagcttctgatt
caactggccgatagctttgtggaaaaaggccacattcatgccacagagatcaggaaatgg
gtgaccacagtggacaagcattacagagacttctccttgaggatgggaaagtaccggtac
tccctggagaaagccctcggcgtcaacacagaggacaataaggacttggagctggacatc
atcccagcaagcctttcagatcgtgaggtcaagctacgggatgccaaccacgaagtcaat
gaagagaagcggaagtcagcccggaagaaagaattcattatggctgaattactgcagaca
gagaaggcgtatgtaagggacttacatgagtgcttagagacctacctgtgggaaatgacc
agtggcgtggaggagatcccccctgggatccttaataaagagcatatcatctttggcaac
atccaggagatctacgattttcataacaacatcttcctcaaagagctggagaagtatgag
cagctgcctgaggatgtgggacactgctttgttacctgggcagacaaatttcagatgtac
gtcacctactgtaaaaacaagcctgattccaaccagctgatcctggagcatgcaggcacc
ttctttgatgagatacagcagcggcacggtctggccaactccatctcttcctacctaatc
aagcccgtccagaggatcaccaagtaccagctgctcctgaaggaacttttaacttgctgc
gaagaagggaagggagagctcaaggatggcctggaggtgatgctcagtgtcccaaagaaa
gccaatgatgccatgcatgtcagcatgctggaagggttcgacgagaacctggatgtgcag
ggggagctgattctccaggatgcctttcaagtgtgggacccaaagtcactgatccggaag
gggcgagagcggcacttgttcctctttgagatctccttggtttttagcaaggagatcaaa
gactcttcaggacacacgaaatatgtttacaagaacaagctactgacctcagagctgggt
gtgacggagcacgtagaaggtgatccctgcaaattcgccttgtggtctgggcgcacccct
tcctcagacaataaaacagtgctgaaagcctccaacatagaaaccaagcaggagtggatc
aagaacattcgagaggtgattcaagagaggatcattcacctgaaaggagctttaaaggag
ccaattcaactccccaaaacaccagccaaacagaggaacaatagtaagagggatggagtg
gaggatgttgacagccagggggatggaagcagccagccagacaccatctctatcgcctct
aggacctctcagaatacagtggacagtgacaagctctctggcggatgtgagttgaccgtg
gtcctccaggacttcaatgcaggccacagcagcgagctgaccatccaggtgggacagacg
gtggagctgctggagcggcccagcgagcggccgggctggtgtctggtccgcaccacggaa
aggagccccccgcaagagggcctggttcccagcagcgccctgtgcatctcccattcccga
agcagcgtggagatggactgcttcttccccctggtgaaagatgcatactcccattcctca
agtgaaaacggaggcaagtctgagtcagtggccaacctgcagtctcagccctccctgaac
tccatccacagctcccccggtcccaagcgttccactaacacccttaagaagtggctgacg
agccccgtgcgccggctcaacagcgggaaagcagatggaaacatcaagaagcagaagaaa
gtacgagatggccggaagagcttcgacctgggatctcccaagcctggggatgagacgacc
cctcagggagacagtgcagatgagaagaacaagaaaggatggggtgaagatgagccagat
gaagagtcacacacccccctccctccacctatgaagatctttgacaatgaccctacgcag
gacgagatgtcctcctctttgctagcagcccggcaggcttccactgaagtaccttctgct
gcagaccttgtcagtgcaatagaacaattggtcaaaagcaagctgagtctagaaggaggc
tcataccggggaagcctgaaggaccctgtaggctgcctgaatgagggaatgaccccaccc
acacctcctagaaacctggaagaagaacagaaagccaaggccctgaggggcaggatgttt
gtcttgaatgagctggtacagacagaaaaagactatgtcaaagatctggggattgtggtg
gagggcttcatgaagagaatagaagaaaagggtgtccctgaggacatgcgaggaaaggat
aaaatcgtgtttggaaatattcaccagatttacgactggcataaggattttttcctggct
gaactggaaaaatgtatccaggagcaagacaggctgggacagctcttcatcaaacacgag
cggaagctgcacatctacgtgtggtactgccagaacaagccgcgctcagagtacatcgtc
gcggagtacgacgcttactttgaagaggtgaaacaggagataaatcaaaggctgacactt
agtgacttccttatcaagcccattcagagaatcacaaaataccagttgctcctcaaggac
ttcctgagatacagcgagaaggctggtttggagtgttcagatatcgagaaagcagtggag
ttaatgtgccttgttccaaaacgctgcaatgacatgatgaatctgggacgcctgcagggc
tttgagggcaccctgaccgctcaggggaagctgctgcagcaggacacgttctatgtgatt
gagctggacgcgggcatgcagtcccggaccaaggagaggcgcgtgttcctctttgagcaa
atcgtcatcttcagtgaactgctaaggaagggatccctcaccccgggctacatgttcaaa
aggagcatcaagatgaattacttggtcctggaggagaacgtggacaatgacccctgcaag
tttgcactcatgaacagggagacttcagagagggtcattctgcaagctgccaacgcggac
atccagcaggcctgggtgcaggacatcaatcaagtcttagaaacacagcgagacttccta
aatgcactacagtcgcccattgagtaccagcggaaagaaaggaacacagctgtgatgagg
tcccagccatctagagttccccaagccagccccaggccctactcctctgtccccgggggc
tctgacaagcccccaaagggctccagctataacccgcctctgccacccctgaagatatct
acctccaatggcagtccagggtttgactatcaccagcctggggaaaagtttgaggccacc
aagcagggcgacctggggggctgcaatgggacctcctccatggccgtgatcaaagattac
tatgcactgaaggagaacgaaatctgtgtgagccaaggtgaggtagtccaggtcctcgcc
gtcaaccagcagaacatgtgcctggtgtaccagccggccagcgactgttcccctgcggcc
gagggctgggtcccaggcagcgtcctggcacccctcaccaaagccaccgcggcagcagaa
agtagtgacggaagcatcaagaagtcatgttcatggcataccctacgaatgagaaagcgg
gcggaagtggagaacacgggtaaaaatgaagccacagggcctcgtaaacccaaggatatt
ctgggcaacaaagtctctgttaaagagacgaacagttccgaggagtcagagtgtgatgat
cttgaccctaatactagcatggagatcttaaatccaaatttcatccaagaagtggcccca
gaattccttgtgcccttagtggatgtgacctgcttgcttggggacacagtgacattgcag
tgcaaagtctgtgggcggccgaagcccaccatcacctggaagggtccagaccagaacatt
cttgacaccgacaacagctcggccacatacaccgtctcctcctgtgattctggggaaatc
accctgaagatctgcaatctgatgccccaagacagtgggatttatacctgcatagcaacg
aacgaccatggcaccacatctacgtctgctacagttaaagtgcaaggtgttccagcagcc
cctaaccgccccattgcccaggaaagaagctgcacttctgtgattctccgctggctgcct
ccctccagcactgggaactgcactatttctggttacaccgtggagtaccgggaggaaggt
tcccaggcctggcagcagtctgtagcttcgaccttggacacttacctcgtcatcgaagac
ctcagccctgggagtccttatcagttcagagtcagcgccagtaacccctgggggatcagc
cttcccagcgagccctcagagtttgtgcgactcccagagtacgatgctgctgctgatggt
gccaccatttcttggaaggataattttgattcagcttatactgagctgaatgaaattgga
agaggccgtttctccattgtaaagaaatgcattcacaaagctacccgcaaggatgtcgct
gtgaaatttgttagcaaaaaaatgaagaaaaaagagcaggccgcccacgaggctgcccta
cttcagcacctgcagcacccccagtacatcactctccatgacacttatgagtcccccaca
tcctacatcctgattttggaactgatggatgatggccggctcttagactaccttatgcat
cacgatgagctgatggaagagaaagtagctttctatatccgagacatcatagaagctctg
cagtatcttcacaactgcagggtggcccatttggacatcaagccggaaaacctgctcatc
gaccttcgcattccagtacctcgagtgaagctcatcgacctggaggatgccgtccagatc
tcgggccacttccacatccaccacctgctggggaaccccgagtttgctgccccagaagtg
atccaaggcatccccgtctccctgggcacagatatctggagcatcggggtgctgacatat
gtcatgctgagtggggtgtcccccttcttggatgagagtaaagaggagacatgtatcaat
gtgtgcagggtggacttcagcttcccgcacgaatacttctgtggtgtgagcaatgccgcc
agagacttcatcaatgtgatcctacaggaagactttcggaggaggcccacggcagccacc
tgcctgcagcatccctggctgcagccccacaatggcagctactccaagatccccctggac
acctcccgcctggcgtgcttcatagaacgccgcaagcatcagaacgacgtgcggcctatc
cccaacgtcaagagctacatcgtcaaccgagtaaaccaagggacatag

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Ontology (5)   
   KEGG BRITE (5)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (4)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   OC (1)   
Protein sequence (13)   
   RefSeq(pep) (13)   
DNA sequence (13)   
   RefSeq(nuc) (13)   
Protein domain (24)   
   Pfam (24)   
All databases (61)   

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