KEGG   Pan troglodytes (chimpanzee): 100614992
Entry
100614992         CDS       T01005                                 
Symbol
SRD5A2
Name
(RefSeq) 3-oxo-5-alpha-steroid 4-dehydrogenase 2 isoform X1
  KO
K12344  3-oxo-5-alpha-steroid 4-dehydrogenase 2 [EC:1.3.1.22]
Organism
ptr  Pan troglodytes (chimpanzee)
Pathway
ptr00140  Steroid hormone biosynthesis
ptr01100  Metabolic pathways
ptr05215  Prostate cancer
Module
ptr_M00976  C19-Steroid hormone biosynthesis, pregnenolone => testosterone => dihydrotestosterone
Brite
KEGG Orthology (KO) [BR:ptr00001]
 09100 Metabolism
  09103 Lipid metabolism
   00140 Steroid hormone biosynthesis
    100614992 (SRD5A2)
 09160 Human Diseases
  09162 Cancer: specific types
   05215 Prostate cancer
    100614992 (SRD5A2)
Enzymes [BR:ptr01000]
 1. Oxidoreductases
  1.3  Acting on the CH-CH group of donors
   1.3.1  With NAD+ or NADP+ as acceptor
    1.3.1.22  3-oxo-5alpha-steroid 4-dehydrogenase (NADP+)
     100614992 (SRD5A2)
SSDB
Motif
Pfam: Steroid_dh DUF1295 DUF6832
Other DBs
NCBI-GeneID: 100614992
NCBI-ProteinID: XP_016803788
Ensembl: ENSPTRG00000044930
VGNC: 58081
Position
2A:complement(31545246..31731425)
AA seq 214 aa
MTSQGMPRTANHCQKLGTLKTFVYSLLNRGRPYPAILILRGIAFCTGNGVLQGYYLIYCA
EYPDGWYTDIRFSLACLPVVLLFITSWLQDVDCSSRHYIWQSRQEERRSVFLFILGMGIN
IHSDYILRQLRKPGEISYRIPQGGLFTYVSGANFLGEIIEWIGYALATWSLPALAFAFFS
LCFLGLRAFHHHRFYLKMFEDYPKSRKALIPFIF
NT seq 645 nt   +upstreamnt  +downstreamnt
atgacaagccaaggaatgccaaggactgcaaaccattgccagaagctaggaacactcaag
acatttgtgtactcactgctcaatcgagggaggccttatccagctatactcattctcaga
ggcattgccttctgcactggaaatggagtccttcaaggctactatctgatttactgtgct
gaataccctgatgggtggtacacagacatacggtttagcttggcatgtttacctgtggtc
ctcttattcatcacttcatggttgcaagatgttgactgtagctcaaggcattacatctgg
caatcaagacaggaagaaagacgaagtgtcttcttatttattttgggaatgggaataaac
attcatagtgactatatattgcgccagctcaggaagcctggagaaatcagctacaggatt
ccacaaggtggcttgtttacgtatgtttctggagccaatttcctcggtgagatcattgaa
tggatcggctatgccctggccacttggtccctcccagcacttgcatttgcatttttctca
ctttgtttccttgggctgcgagcttttcaccaccataggttctacctcaagatgtttgag
gactaccccaaatctcggaaagcccttattccattcatcttttaa

  All links  
Ontology (2)   
   KEGG BRITE (2)   
Pathway (4)   
   KEGG PATHWAY (3)   
   KEGG MODULE (1)   
Chemical substance (11)   
   KEGG COMPOUND (11)   
Chemical reaction (5)   
   KEGG ENZYME (1)   
   KEGG REACTION (4)   
Genome (1)   
   KEGG GENOME (1)   
Gene (6)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
   VGNC (1)   
Protein sequence (2)   
   RefSeq(pep) (2)   
DNA sequence (2)   
   RefSeq(nuc) (2)   
Protein domain (3)   
   Pfam (3)   
All databases (36)   

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