KEGG   Pan troglodytes (chimpanzee): 454887
Entry
454887            CDS       T01005                                 
Symbol
ITGB4
Name
(RefSeq) integrin beta-4 isoform X1
  KO
K06525  integrin beta 4
Organism
ptr  Pan troglodytes (chimpanzee)
Pathway
ptr04151  PI3K-Akt signaling pathway
ptr04510  Focal adhesion
ptr04512  ECM-receptor interaction
ptr04810  Regulation of actin cytoskeleton
ptr04820  Cytoskeleton in muscle cells
ptr05165  Human papillomavirus infection
ptr05410  Hypertrophic cardiomyopathy
ptr05412  Arrhythmogenic right ventricular cardiomyopathy
ptr05414  Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:ptr00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04151 PI3K-Akt signaling pathway
    454887 (ITGB4)
  09133 Signaling molecules and interaction
   04512 ECM-receptor interaction
    454887 (ITGB4)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    454887 (ITGB4)
  09142 Cell motility
   04820 Cytoskeleton in muscle cells
    454887 (ITGB4)
   04810 Regulation of actin cytoskeleton
    454887 (ITGB4)
 09160 Human Diseases
  09172 Infectious disease: viral
   05165 Human papillomavirus infection
    454887 (ITGB4)
  09166 Cardiovascular disease
   05410 Hypertrophic cardiomyopathy
    454887 (ITGB4)
   05412 Arrhythmogenic right ventricular cardiomyopathy
    454887 (ITGB4)
   05414 Dilated cardiomyopathy
    454887 (ITGB4)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:ptr04147]
    454887 (ITGB4)
   04515 Cell adhesion molecules [BR:ptr04515]
    454887 (ITGB4)
   04090 CD molecules [BR:ptr04090]
    454887 (ITGB4)
Exosome [BR:ptr04147]
 Exosomal proteins
  Exosomal proteins of colorectal cancer cells
   454887 (ITGB4)
  Exosomal proteins of bladder cancer cells
   454887 (ITGB4)
Cell adhesion molecules [BR:ptr04515]
 Integrins
  Integrin beta subunits
   454887 (ITGB4)
CD molecules [BR:ptr04090]
 Proteins
  454887 (ITGB4)
SSDB
Motif
Pfam: Integrin_beta fn3 Calx-beta Integrin_B_tail Pur_ac_phosph_N I-EGF_1 PSI_integrin EGF_2 SEA
Other DBs
NCBI-GeneID: 454887
NCBI-ProteinID: XP_016786379
Ensembl: ENSPTRG00000009653
VGNC: 9339
Position
17:68833324..68869865
AA seq 1875 aa
MAGPRPSPWARLLLAALISVSLSGTLANRCKKAPVKSCTECVRVDKDCAYCTDELFRDRR
CNTQAELLAAGCQRESIMVMESSFQITEETQIDTTLRRSQMSPQGLRVRLRPGEERHFEL
EVFEPLESPVDLYILMDFSNSMSDDLDNLKKMGQNLARVLSQLTSDYTIGFGKFVDKVSV
PQTDMRPEKLKEPWPNSDPPFSFKNVISLTEDVDEFRNKLQGERISGNLDAPEGGFDAIL
QTAVCTRDIGWRPDSTHLLVFSTESAFHYEADGANVLAGIMSRNDERCHLDTTGTYTQYR
TQDYPSVPTLVRLLAKHNIIPIFAVTNYSYSYYEKLHTYFPVSSLGVLQEDSSNIVELLE
EAFNRIRSNLDIRALDSPRGLRTEVTSKMFQKTKTGSFHIRRGEVGIYQVQLRALEHVDG
THVCQLPEDQKGNIHLKPSFSDGLKMDAGIICDVCTCELQKEVRSARCSFNGDFMCGHCV
CSEGWSGQTCNCSTGSLSDIQPCLREGEDKPCSGRGECQCGHCVCYGEGRYEGQFCEYDN
FQCPRTSGFLCNDRGRCSMGQCVCEPGWTGPSCDCPLSNATCIDSNGGICNGRGHCECGR
CHCHQQSLYTDTICEINYSAIHPGLCEDLRSCVQCQAWGTGEKKGRTCEECNFKVKMVDE
LKRAEEVVVRCSFRDEDDDCTYSYTMEGDGAPGPNSTVLVHKKKDCPPGSFWWLIPLLLL
LLPLLALLLLLCWKYCACCKACLALLPCCNRGHMVGFKEDHYMLRENLMASDHLDTPMLR
SGNLKGRDVVRWKVTNNMQRPGFATHAASINPTELVPYGLSLRLARLCTENLLKPDTREC
AQLRQEVEENLNEVYRQISGVHKLQQTKFRQQPNAGKKQDHTIVDTVLMAPRSAKPALLK
LTEKQVEQRAFHDLKVAPGYYTLTADQDARGMVEFQEGVELVDVRVPLFIRPEDDDEKQL
LVEAIDVPAGTATLGRRLVNITIIKEQARDVVSFEQPEFSVSRGDQVARIPVIRRVLDGG
KSQVSYRTQDGTAQGNRDYIPVEGELLFQPGEAWKELQVKLLELQEVDSLLRGRQVRRFH
VQLSNPKFGAHLGQPHSTTIIIRDPDELDRSFTSQMLSSQPPPHGDLGAPQNPNAKAAGS
RKIHFNWLPPSGKPMGYRVKYWIQGDSESEAHLLDSKVPSVELTNLYPYCDYEMKVCAYG
AQGEGPYSSLVSCRTHQEVPSEPGRLAFNVVSSTVTQLSWAEPAETNGEITAYEVCYGLV
NDDNRPIGPMKKVLVDNPKNRMLLIENLRESQPYRYTVKARNGAGWGPEREAIINLATQP
KRPMSIPIIPDIPIVDAQSGEDYDSFLMYSDDVLRSPSGSQRPSVSDDTGCGWKFEPLLG
EELDLRRVTWRLPPELIPRLSASSGRSSDAEAPHGPPDDGGAGGKGGSLPRSATPGPPGE
HLVNGRMDFAFPGSTNSLHRMTTTSAAAYGTHLSPHVPHRMLSTSSTLTRDYNSLTRSEH
SHSTTLPRDYSTLTSVSSHGLPPIWEHGRSRLPLSWALGSRSRAQMKGFPASRGPRDSII
LAGRPAAPSWGPDFRLTAGVPDTPTRLVFSALGPTSLRVSWQEPRCERPLQGYSVEYQLL
NGGELHRLNIPNPAQTSVVVEDLLPNHSYVFRVRAQSQEGWGREREGVITIESQVHPQSP
LCPLPGSAFTLSTPSAPGPLVFTALSPDSLQLSWERPRRPNGDIVGYLVTCEMAQGGGPA
TTFRVDGDSPESRLTVPGLSENVPYKFKVQARTTEGFGPEREGIITIESQDGGPFPQLGS
HAGLFQHPLQSEYSSITTTHTSATEPFLVDGLTLGAQHLEAGGSLTRHVTQEFVSRTLTT
SGTLSTQVDQQFFQT
NT seq 5628 nt   +upstreamnt  +downstreamnt
atggcagggccacgccccagcccatgggccaggctgctcctggcagccttgatcagcgtc
agcctctctgggaccttggcaaaccgctgcaagaaggccccagtgaagagctgcacggag
tgtgtccgtgtggataaggactgtgcctactgcacagacgagctattcagggaccggcgc
tgcaacactcaggcggagctgctggccgcgggctgccagcgggagagcatcatggtcatg
gagagcagcttccagatcacagaggagacccagattgacaccaccctgcggcgcagccag
atgtccccccagggcctgcgggtccgtctgcggcccggtgaggagcggcactttgagctg
gaggtgtttgagccactggagagccccgtggacctgtacatcctcatggacttctccaac
tccatgtccgatgatctggacaacctcaagaagatggggcagaacctggctcgggtcctg
agccagctcaccagcgactacactattggatttggcaagtttgtggacaaagtcagcgtc
ccgcagacggacatgaggcctgagaagctgaaggagccctggcccaacagtgaccccccc
ttctccttcaagaacgtcatcagcctgacagaagatgtggatgagttccggaataaactg
cagggagagcggatctcaggcaacctggatgctcctgagggcggcttcgatgccatcctg
cagacagctgtgtgcacgagggacattggctggcgcccggacagcacccacctgctggtc
ttctccaccgagtcagccttccactatgaggctgatggcgccaacgtgctggctggcatc
atgagccgcaacgatgaacggtgccacctggacaccacgggcacctacacccagtacagg
acacaggactacccgtcggtgcccaccctggtgcgcctgctcgccaagcacaacatcatc
cccatctttgctgtcaccaactactcctatagctactacgagaagcttcacacctatttc
cctgtctcctcactgggggtgctgcaggaggactcgtccaacatcgtggagctgctggag
gaggccttcaatcgaatccgctccaacctggacatccgggccctagacagcccccgaggc
cttcggacagaggtcacctccaagatgttccagaagacgaagactgggtcctttcacatc
cggcggggggaagtgggtatataccaggtgcagctgcgggcccttgagcacgtggatggg
acgcacgtgtgccagctgccggaggaccagaagggcaacatccatctgaaaccttccttc
tccgacggcctcaagatggacgcgggcatcatctgtgatgtgtgcacctgcgagctgcaa
aaagaggtgcggtcagctcgctgcagcttcaatggagacttcatgtgcggacactgtgtg
tgcagtgagggctggagtggccagacctgcaactgctccaccggctctctgagtgacatt
cagccctgcctgcgggagggcgaggacaagccgtgctccggccgtggggagtgccagtgc
gggcactgtgtgtgctacggcgaaggccgctacgagggtcagttctgcgagtatgacaac
ttccagtgtccccgcacttccgggttcctctgcaatgaccgaggacgctgctccatgggc
cagtgtgtgtgtgagcctggttggacaggcccaagctgtgactgtcccctcagcaatgcc
acctgcatcgacagcaatgggggcatctgtaatggacgtggccactgtgagtgtggccgc
tgccactgccaccagcagtcgctctacacggacaccatctgcgagatcaactactcggcg
atccacccgggcctctgcgaggacctacgctcctgtgtgcagtgccaggcgtggggcact
ggggagaagaaggggcgcacgtgtgaggaatgcaacttcaaggtcaagatggtggatgag
cttaagagagccgaggaggtggtggtgcgctgctccttccgggacgaggatgacgactgc
acctacagctacaccatggaaggtgacggcgcccctgggcccaacagcactgtcctggtg
cacaagaagaaggactgccctccgggctccttctggtggctcatccccctgctcctcctc
ctcctgccgctcctggccctgctactgctgctatgctggaagtactgtgcctgctgcaag
gcctgcctggcacttctcccgtgctgcaaccgaggtcacatggtgggctttaaggaagac
cactacatgctgcgggagaacctgatggcctctgaccacttggacacgcccatgctgcgc
agcgggaacctcaagggccgtgatgtggtccgctggaaggtcaccaacaacatgcagcgg
cctggctttgccactcatgccgccagcatcaaccccacagagctggtgccctacgggctg
tccttgcgcctggcccgcctttgcaccgagaacctgctgaagcctgacactcgggagtgc
gcccagctgcgccaggaggtggaggagaatctgaacgaggtctacaggcagatctccggt
gtacacaagctccagcagaccaagttccggcagcagcccaatgccgggaaaaagcaagac
cacaccattgtggacacagtgctgatggcgccccgctcggccaagccggccctgctgaag
cttacagagaagcaggtggaacagagggccttccacgacctcaaggtggcccctggctac
tacaccctcactgcagaccaggacgcccggggcatggtggagttccaggagggcgtggag
ctggtggacgtacgggtgcccctctttatccggcctgaggatgacgacgagaagcagctg
ctggtggaggccatcgacgtgcccgcaggcactgccaccctcggccgccgcctggtaaac
atcaccatcatcaaggagcaagccagagacgtggtgtcctttgagcagcctgagttctcg
gtcagccgcggggaccaggtggcccgcatccctgtcatccggcgtgtcctggacggcggg
aagtcccaggtctcctaccgcacacaggatggcaccgcgcagggcaaccgggactacatc
cccgtggagggcgagctgctgttccagcctggggaggcctggaaagagctgcaggtgaag
ctcctggagctgcaagaggttgactccctcctgcggggccgccaggtccgccgtttccac
gtccagctcagcaaccctaagtttggggcccacctgggccagccccactccaccaccatc
atcatcagggacccagatgaactggaccggagcttcacgagtcagatgttgtcatcacag
ccaccccctcacggcgacctgggcgccccgcagaaccccaatgctaaggccgctgggtcc
aggaagatccatttcaactggctgcccccttctggcaagccaatggggtacagggtaaag
tactggattcagggtgactctgagtccgaagcccacctgctcgacagcaaggtgccctca
gtggagctcaccaacctgtacccgtattgcgactatgagatgaaggtgtgcgcctacggg
gctcagggcgagggaccctacagctccctggtgtcctgccgcacccaccaggaagtgccc
agcgagccagggcgtctggccttcaatgtcgtctcctccacggtgacccagctgagctgg
gctgagccggctgagaccaacggtgagatcacagcctacgaggtctgctatggcctggtc
aacgatgacaaccgacctattgggcccatgaagaaagtgctggttgacaaccctaagaac
cggatgctgcttattgagaaccttcgggagtcccagccctaccgctacacggtgaaggcg
cgcaacggggccggctgggggcccgagcgggaggccatcatcaacctggccacccagccc
aagaggcccatgtccatccccatcatccctgacatccctatcgtggacgcccagagcggg
gaggactacgacagcttcctcatgtacagcgatgacgttctacgctctccatcgggcagc
cagaggcccagcgtctccgatgacactggctgcggctggaagttcgagcccctgctgggg
gaggagctggacctgcggcgcgtcacgtggcggctgcccccggagctcatcccgcgcctg
tcggccagcagcgggcgctcctccgacgccgaggcgccccacgggcccccggacgacggc
ggcgcgggcgggaagggcggcagcctgccccgcagtgcgacacccgggccccccggagag
cacctggtgaatggccggatggactttgccttcccgggcagcaccaactccctgcacagg
atgaccacgaccagtgctgctgcctatggcacccacctgagcccacacgtgccccaccgc
atgctaagcacatcctccaccctcacacgggactacaactcactgacccgctcggaacac
tcacactcgaccacactgcccagggactactccaccctcacctccgtctcctcccacggc
ctccctcccatctgggaacacgggaggagcaggcttccgctgtcctgggccctggggtcc
cggagtcgggctcagatgaaagggttccccgcttccaggggcccacgagactctataatc
ctggctgggaggccagcagcgccctcctggggcccagactttcgcctgactgctggtgtg
cccgacacgcccacccgcctggtgttctctgccctggggcccacatctctcagagtgagc
tggcaggagccgcggtgcgagcggccgctgcagggctacagcgtggagtaccagctgctg
aatggcggcgagctgcatcggctcaacatccccaaccctgcccagacctcggtggtggtg
gaagacctcctgcccaaccactcctacgtgttccgcgtgcgggcccagagccaggaaggc
tggggccgagagcgtgagggtgtcatcaccatcgaatcccaggtgcacccgcagagccca
ctgtgtcccctgccaggctccgccttcactttgagcactcccagtgccccaggcccgctg
gtgttcactgccctgagcccagactcgctgcagctgagctgggagcggccacggaggccc
aatggggatatcgtcggctacctggtgacctgtgagatggcccaaggaggagggccagcc
accacattccgggtggatggagacagccccgagagccggctgaccgtgccgggcctcagc
gagaacgtgccctacaagttcaaggtgcaggccaggaccactgagggcttcgggccagag
cgcgagggcatcatcaccatagagtcccaggatggaggacccttcccgcagctgggcagc
catgccgggctcttccagcacccgctgcaaagcgagtacagcagcatcaccaccacccac
accagcgccaccgagcccttcctagtggatgggctgaccctgggggcccagcacctggag
gcaggcggctccctcacccggcatgtgacccaggagtttgtgagccggacactgaccacc
agcggaaccctcagcacccaggtggaccaacagttcttccaaacctga

  All links  
Ontology (4)   
   KEGG BRITE (4)   
Pathway (9)   
   KEGG PATHWAY (9)   
Genome (1)   
   KEGG GENOME (1)   
Gene (6)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
   VGNC (1)   
Protein sequence (5)   
   RefSeq(pep) (5)   
DNA sequence (9)   
   RefSeq(nuc) (5)   
   GenBank (2)   
   EMBL (2)   
Protein domain (9)   
   Pfam (9)   
All databases (43)   

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