KEGG   Pan troglodytes (chimpanzee): 460745
Entry
460745            CDS       T01005                                 
Symbol
ATR
Name
(RefSeq) serine/threonine-protein kinase ATR isoform X1
  KO
K06640  serine/threonine-protein kinase ATR [EC:2.7.11.1]
Organism
ptr  Pan troglodytes (chimpanzee)
Pathway
ptr03460  Fanconi anemia pathway
ptr04110  Cell cycle
ptr04115  p53 signaling pathway
ptr04218  Cellular senescence
ptr05165  Human papillomavirus infection
ptr05166  Human T-cell leukemia virus 1 infection
ptr05170  Human immunodeficiency virus 1 infection
Brite
KEGG Orthology (KO) [BR:ptr00001]
 09120 Genetic Information Processing
  09124 Replication and repair
   03460 Fanconi anemia pathway
    460745 (ATR)
 09140 Cellular Processes
  09143 Cell growth and death
   04110 Cell cycle
    460745 (ATR)
   04115 p53 signaling pathway
    460745 (ATR)
   04218 Cellular senescence
    460745 (ATR)
 09160 Human Diseases
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    460745 (ATR)
   05170 Human immunodeficiency virus 1 infection
    460745 (ATR)
   05165 Human papillomavirus infection
    460745 (ATR)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:ptr01001]
    460745 (ATR)
  09182 Protein families: genetic information processing
   03400 DNA repair and recombination proteins [BR:ptr03400]
    460745 (ATR)
Enzymes [BR:ptr01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.1  non-specific serine/threonine protein kinase
     460745 (ATR)
Protein kinases [BR:ptr01001]
 Serine/threonine kinases: Other
  PIKK family [OT]
   460745 (ATR)
DNA repair and recombination proteins [BR:ptr03400]
 Eukaryotic type
  Check point factors
   Other check point factors
    460745 (ATR)
SSDB
Motif
Pfam: PI3_PI4_kinase FAT UME FATC HEAT Mad3_BUB1_I TPR_1 TRIF-NTD THP2
Other DBs
NCBI-GeneID: 460745
NCBI-ProteinID: XP_016797578
Ensembl: ENSPTRG00000015483
VGNC: 6166
UniProt: K7BXR2
Position
3:complement(140540953..140670654)
AA seq 2646 aa
MGEHGLELASMIPALRELGSATPEEYNTVVQKPRQILCQFIDRILTDVNVVAVELVKKTD
SQPTSVMLLDFIQHIMKSSPLMFVNVSGSHEAKGSCIEFSNWIITRLLRIAATPSCHLLH
KKICEVICSLLFLFKSKSPAIFGVLTKELLQLFEDLVYLHRRNVMSHAVEWPVVMSRFLS
QLDEHMGYLQSAPLQLMSMQNLEFIEVTLLTVLTRIIAIVFFRRQELLLWQIGCVLLEYG
SPKIKSLAISFLTELFQLGGLPAQPASTFFSSLLELLKHLVEMDTDQLKLYEEPLSKLIK
TLFPFEAEAYRNIEPVYLNMLLEKLCVMFEDGVLMRLKSDLLKAALCHLLQYFLKFVPAG
YESALQVRKVYVRNICKALLDVLGIQVDAEYLLGPLYAALKMESMEIIEEIQCQTQQENL
SSNSDGISPKRRRLSSSLNPSKRAPKQTEEIKHVDMNQKSILWSALKQKAESLQISLEYS
GLKNPVIEMLEGIAVVLQLTALCTVHCSHQNMNCRTFKDCQHKSKKKPSVVITWMSLDFY
TKVLKSCRSLLESVQKPDLEATIDKVVKIYDALIYMQVNSSFEDHILEDLCGMLSLPWIY
SHSDDGCLKLTTFATNLLTLSCRISDSYSPQAQSRCVFLLTLFPRRIFLEWRTAVYNWAL
QSSHEVIRASCVSGFFILLQQQNSCNRVPRILIDKVKDDSDIVKKEFASILGQLVCTLHG
MFYLTSSLTEPFSEHGHVDLFCRNLKATSQHECSSSQLKASVCKPFLFLLKKKTPSPVKL
AFIDNLHHLCKHLDFREDETDVKAVLGTLLNLMEDPDKDVRVAFSGNIKHILESLDSEDG
FIKELFVLRMKEAYTHAQISRNNELKDTLILTTGDIGRAAKGDLVPFALLHLLHCLLSKS
ASVSGAAYTEIRALVAAKSVKLQSFFSQYKKPICQFLVESLHSSQMTALPNTPCQNADMR
KQDVAHQREMALNTLSEIANVFDFPDLNRFLTRTLQVLLPDLAAKASPAASALIRTLGKQ
LNVNRREILINNFKYIFSHLVCSCSKDELERALHYLKNETEIELGSLLRQDFQGLHNELL
LRIGEHYQQVFNGLSILASFASSDDPYQGPRDIISPELMADYLQPKLLGILAFFNMQLLS
SSVGIEDKKMALNSLMSLMKLMGPKHVSSVRVKMMTTLRTGLRFKDDFPELCCRAWDCFV
RCLDHGCLGSLLSHVIVALLPLIHIQPKETAAIFHYLIIENRDAVQDFLHEIYFLPDHPE
LKKIKAVLQEYRKETSESTDLQTTLQLSMKAIQHENVDVRIHALTSLKETLYKNQEKLIK
YATDSETVEPIISQLVTVLLKGCQDANSQARLLCGECLGELGAIDPGRLDFSTTETQGKD
FTFVIETGVEDSSFAYGLLMELTRAYLAYADNSRAQDSAAYAIQELLSIYDCREMETNGP
GHQLWRRFPEHVREILEPHLNTRYKSSQKSTDWSGVKKPIYLSKLGSNFAEWSASWAGYL
ITKVRHDLASKIFTCCSIMMKHDFKVTIYLLPHILVYVLLGCNQEDQQEVYAEIMAVLKH
DDQHTINTQDIASDLCQLSTQTVFSMLDHLTQWARHKFQALKAEKCPHSKSNRNKVDSMV
STVDYEDYQSVTRFLDLIPQDTLAVASFRSKAYTRAVMHFESFITEKKQNIQEHLGFLQK
LYAAMHEPDGVAGVSAIRKAEPSLKEQILEHESLGLLRDATACYDRAIQLEPDQIIHYHG
VVKSMLGLGQLSTVITQVNGVHANRSEWTDELNTYRVEAAWKLSQWDLVENYLAADGKST
TWSVRLGQLLLSAKKRDITAFYDTLKLVRAEQIVPLSAASFERGSYQRGYEYIVRLHMLC
ELEHSIKPLFQHSPGDSSQEDSLNWVARLEMTQNSYRAKEPILALRRALLSLNKRPDYNE
MVGECWLQSARVARKAGHHQTAYNALLNAGESRLAELYVERAKWLWSKGDVHQALIVLQK
GVELCFPENETPPEGKNMLIHGRAMLLVGRFMEETANFESNAIMKKYKDVTACLPEWEDG
HFYLAKYYDKLMPMVTDNKMEKQGDLIRYIVLHFGRSLQYGNQFIYQSMPRMLTLWLDYG
TKAYEWEKAGRSDRVQMRNDLGKINKVITEHTNYLAPYQFLTAFSQLISRICHSHDEVFV
VLMEIIAKVFLAYPQQAMWMMTAVSKSSYPMRVNRCKEILNKAIHMKKSLEKFVGDATRL
TDKLLELCNKPVDGSSSTLSMSTHFKMLKKLVEEATFSEILIPLQSVMIPTLPSILGTHA
NHASHEPFPGHWAYIAGFDDMVEILASLQKPKKISLKGSDGKFYIMMCKPKDDLRKDCRL
MEFNSLINKCLRKDAESRRRELHIRTYAVIPLNDECGIIEWVNNTAGLRPILTKLYKEKG
VYMTGKELRQCMLPKSAALSEKLKVFREFLLPRHPPIFHEWFLRTFPDPTSWYSSRSAYC
RSTAVMSMVGYILGLGDRHGENILFDSLTGECVHVDFNCLFNKGETFEVPEIVPFRLTHN
MVNGMGPMGTEGLFRRACEVTMRLMRDQREPLMSVLKTFLHDPLVEWSKPVKGHSKAPLN
ETGEVVNEKAKTHVLDIEQRLQGVIKTRNRVTGLPLSIEGHVHYLIQEATDENLLCQMYL
GWTPYM
NT seq 7941 nt   +upstreamnt  +downstreamnt
atgggggaacatggcctggagctggcttccatgatccccgccctgcgggagctgggcagt
gccacaccagaggaatataatacagttgtacagaagccaagacaaattctgtgtcaattc
attgaccggatacttacagatgtaaatgttgttgctgtagaacttgtaaagaaaactgac
tctcagccaacctccgtgatgttgcttgatttcatccagcatatcatgaaatcctcccca
cttatgtttgtaaatgtgagtggaagccatgaggccaaaggcagttgtattgaattcagt
aattggatcataacgagacttctgcggattgcagcaactccctcctgtcatttgttacac
aagaaaatctgtgaagtcatctgttcattattatttctttttaaaagcaagagtcctgct
atttttggggtactcacaaaagaattattacaactttttgaagacttggtttacctccat
agaagaaatgtgatgagtcatgctgtggaatggccagtggtcatgagccgatttttaagt
caattagatgaacacatgggatatttacaatcagctcctttgcagttgatgagtatgcaa
aatttagaatttattgaagtcactttattaacggttcttactcgtattattgcaattgtg
ttttttagaaggcaagaactcttactttggcagataggttgtgttctgctagagtatggt
agtccaaaaattaaatccctagcaattagctttttaacagaactttttcagcttggagga
ctaccagcacaaccagctagcacttttttcagctcattgttggaattattaaaacacctt
gtagaaatggatactgaccaattgaaactctatgaagagccattatcaaagctgataaag
acactatttccctttgaagcagaagcttatagaaatattgaacctgtctatttaaatatg
ctgctggaaaaactctgtgtcatgtttgaagacggtgtgctcatgcggcttaagtctgat
ttgctaaaagcagctttgtgccatttactgcagtatttccttaaatttgtgccagctggg
tatgaatctgctttacaagtcaggaaggtctatgtgagaaatatttgtaaagctcttttg
gatgtgcttggaattcaggtagatgcagagtacttgttgggcccactttatgcagctttg
aaaatggaaagtatggaaatcattgaggagattcaatgccaaactcaacaggaaaacctc
agcagtaatagtgatggaatatcacccaaaaggcgtcgtctcagctcgtctctaaaccct
tctaaaagagcaccaaaacagactgaggaaattaaacatgtggacatgaaccaaaagagc
atattatggagtgcactgaaacagaaagctgaatcccttcagatttcccttgaatacagt
ggcctaaagaatcctgttattgagatgttagaaggaattgctgttgtcttacaactgact
gctctgtgtactgttcattgttctcatcaaaacatgaactgccgtactttcaaggactgt
caacataaatccaagaagaagccttctgtagtgataacttggatgtcattggatttttac
acaaaagtgcttaagagctgtagaagtttgttagaatctgttcagaaaccggacctggag
gcaaccattgataaggtggtgaaaatttatgatgctttgatttatatgcaagtaaacagt
tcatttgaagatcatatcctggaagatttatgtggaatgctctcacttccatggatttat
tcccattctgatgatggctgtttaaagttgaccacatttgccactaatcttctaacatta
agctgtaggatttcagatagctattcaccacaggcacaatcacgatgtgtgtttcttctg
actctgtttccaagaagaatattccttgaatggagaacagcagtttacaactgggccctg
cagagctcccatgaagtaatccgggctagttgtgttagtggattttttatcttactgcag
cagcagaattcttgtaacagagttcccaggattcttatagataaagtcaaagatgattct
gacattgtcaagaaagaatttgcttctatacttggtcaacttgtctgtactcttcacggc
atgttttatctgacaagttctttaacagaacctttctctgaacacggacatgtggacctc
ttctgtaggaacttgaaagccacttctcaacatgaatgttcatcttctcaactaaaagct
tctgtctgcaagccattccttttcctactgaaaaaaaaaacacctagtcctgtaaaactt
gctttcatagataatctacatcatctttgtaagcatcttgattttagagaagatgaaaca
gatgtaaaagcagttcttggaactttattaaatttaatggaagatccagacaaagatgtt
agagtggcttttagtggaaatatcaagcacatattggaatccttggactctgaagatgga
tttataaaggagctttttgtcttaagaatgaaggaagcatatacacatgcccaaatatca
agaaataatgagctgaaggataccttgattcttacaacaggggatattggaagggccgca
aaaggagatttggtaccgtttgcactcttacacttattgcattgtttgttatccaagtca
gcatctgtctctggagcagcatacacagaaattagagctctggttgcagctaaaagtgtt
aaactgcaaagttttttcagccagtataagaaacccatctgtcagtttttggtagaatcc
cttcactctagtcagatgacagcacttccgaatactccatgccagaatgctgacatgcga
aaacaagatgtggctcaccagagagaaatggctttaaatacgttgtctgaaattgccaac
gtttttgactttcctgatcttaatcgttttcttactaggacattacaagttctactacct
gatcttgctgccaaagcaagccctgcagcttctgctctcattcgaactttaggaaaacaa
ttaaatgtcaatcgtagagagattttaataaacaacttcaaatatattttttctcatttg
gtctgttcttgttccaaagatgaattagaacgtgcccttcattatctgaagaatgaaaca
gaaattgaactggggagcctgttgagacaagatttccaaggattgcataatgaattattg
ctgcgtattggagaacactatcaacaggtttttaatggtttgtcaatacttgcctcattt
gcatccagtgatgatccatatcagggcccaagagatatcatatcacctgaactgatggct
gattatttacaacccaaattgttgggcattttggctttttttaacatgcagttactgagc
tctagtgttggcattgaagataagaaaatggccttgaacagtttgatgtctttgatgaag
ttaatgggacccaaacatgtcagttctgtgagggtgaagatgatgaccacactgagaact
ggccttcgattcaaggatgattttcctgaattgtgttgcagagcttgggactgctttgtt
cgctgcctggatcatggttgtctgggctcccttctcagtcatgtaatagtagctttgtta
cctcttatacacatccagcctaaagaaactgcagctatctttcactacctcataattgaa
aacagggatgctgtgcaagattttcttcatgaaatatattttttacctgatcatccagaa
ttaaaaaagataaaagccgttctccaggaatacagaaaggagacctctgagagcactgat
cttcagacaactcttcagctctctatgaaggccattcaacatgaaaatgtcgatgttcgt
attcatgctcttacaagcttgaaggaaaccttgtataaaaatcaggaaaaactgataaag
tatgcaacagacagtgaaacagtagaacctattatctcacagttggtgacagtgcttttg
aaaggttgccaagatgcaaactctcaagctcggttgctctgtggggaatgtttaggggaa
ttgggggcgatagatccaggtcgattagatttctcaacaactgaaactcaaggaaaagat
tttacatttgtgattgagactggagtagaagattcaagctttgcctatggattattgatg
gagctaacaagagcttaccttgcgtatgctgataatagccgagctcaagattcagctgcc
tatgccattcaggagttgctttctatttatgactgtagagagatggagaccaacggccca
ggtcaccaattgtggaggagatttcctgagcatgttcgggaaatactagaacctcatcta
aataccagatacaagagttctcagaagtcaaccgattggtctggagtaaagaagccaatt
tacttaagtaaattgggtagtaactttgcagaatggtcagcatcttgggcaggttatctt
atcacaaaggttcgacatgatcttgccagtaaaattttcacctgctgtagcattatgatg
aagcatgatttcaaagtgaccatctatcttcttccacatattctggtgtatgtcttactg
ggttgtaatcaagaagatcagcaggaggtttatgcagaaattatggcagttctaaagcat
gacgatcagcataccataaatacccaagacattgcatctgatctgtgtcaactcagtaca
cagactgttttctccatgcttgaccatctcacacagtgggcaaggcacaaatttcaggca
ctgaaagctgagaaatgtccacacagcaaatcaaacagaaataaggtagactcaatggta
tctactgtggattatgaagactatcagagtgtaacccgttttctagacctcataccccag
gatactctggcagtagcttcctttcgctccaaagcatacacacgagctgtaatgcacttt
gaatcatttattacagaaaagaagcaaaatattcaggaacatcttggatttttacagaaa
ttgtatgctgctatgcatgaacctgatggagtggccggagtcagtgcaattagaaaggca
gaaccatctctaaaagaacagatccttgaacatgaaagccttggcttgctgagggatgcc
actgcttgttatgacagggctattcagctagaaccagaccagatcattcattatcatggt
gtagtaaagtccatgttaggtcttggtcagctgtctactgttatcactcaggtgaatgga
gtgcatgctaacaggtccgagtggacagatgaattaaacacgtacagagtggaagcagct
tggaaattgtcacagtgggatttggtggaaaactatttggcagcagatggaaaatctaca
acatggagtgtcagactgggacagctattattatcagccaaaaaaagagatatcacagct
ttttatgacacactgaaactagtgagagcagaacaaattgtacctctttcagctgcaagc
tttgaaagaggctcctaccaacgaggatatgaatatattgtgagattgcacatgttgtgt
gagttggagcatagcatcaaaccacttttccagcattctccaggtgacagttctcaagaa
gattctctaaactgggtagctcgactagaaatgacccagaattcctacagagccaaggag
cctatcctggctctccggagggctttactaagcctcaacaaaagaccagattacaatgaa
atggttggagaatgctggctgcagagtgccagagtagctagaaaggctggtcaccaccag
acagcctacaatgctctccttaatgcaggggaatcacgactcgctgaactgtacgtggaa
agggcaaagtggctctggtccaagggtgatgttcaccaggcactaattgttcttcaaaaa
ggtgttgaattatgttttcctgaaaatgaaaccccacctgagggtaagaacatgttaatc
catggtcgagctatgctactagtgggccgatttatggaagaaacagctaactttgaaagc
aatgcaattatgaaaaaatataaggatgtgaccgcatgcctgccagaatgggaggatggg
catttttaccttgccaagtactatgacaaattgatgcccatggtcacagacaacaaaatg
gaaaagcaaggtgatctcatccggtatatagttcttcattttggcagatctctacaatat
ggaaatcagttcatatatcagtcaatgccacgaatgttaactctatggcttgattatggt
acaaaggcatatgaatgggaaaaagctggccgctccgatcgtgtacaaatgaggaatgat
ttgggtaaaataaacaaggttatcacagagcatacaaactatttagctccatatcaattt
ttgactgctttttcacaattgatctctcgaatttgtcattctcacgatgaagtttttgtt
gtcttgatggaaataatagccaaagtatttctagcctatcctcaacaagcaatgtggatg
atgacagctgtgtcaaagtcatcttatcccatgcgtgtgaacagatgcaaggaaatcctc
aataaagctattcatatgaaaaaatccttagagaagtttgttggagatgcaactcgccta
acagataagcttctagaattgtgcaataaaccggttgatggaagtagttccacattaagc
atgagcactcattttaaaatgcttaaaaagctggtagaagaagcaacatttagtgaaatc
ctcattcctctacaatcagtcatgatacctacacttccatcaattctgggtacccatgct
aaccatgctagccatgaaccatttcctggacattgggcctatattgcagggtttgatgat
atggtggaaattcttgcttctcttcagaaaccaaagaagatttctttaaaaggctcagat
ggaaagttctacatcatgatgtgtaagccaaaagatgacctgagaaaggattgtagacta
atggaattcaattccttgattaataagtgcttaagaaaagatgcagagtctcgtagaaga
gaacttcatattcgaacatatgcagttattccactaaatgatgaatgtgggattattgaa
tgggtgaacaacactgctggtttgagacctattctgaccaaactatataaagaaaaggga
gtgtatatgacaggaaaagaacttcgccagtgtatgctaccaaagtcagcagctttatct
gaaaaactcaaagtattccgagaatttctcctgcccaggcatcctcctatttttcatgag
tggtttctgagaacattccctgatcctacatcatggtacagtagtagatcagcttactgc
cgttccactgcagtaatgtcaatggttggttatattctggggcttggagaccgtcatggt
gaaaatattctctttgattctttgactggtgaatgcgtacatgtagatttcaattgtctt
ttcaataagggagaaacctttgaagttccagaaattgtaccatttcgcctgactcataat
atggttaatggaatgggtcctatgggaacagagggtctttttcgaagagcatgtgaagtt
acaatgaggctgatgcgtgatcagcgagagcctttaatgagtgtcttaaagacttttcta
catgatcctcttgtggaatggagtaaaccagtgaaagggcattccaaagcgccactgaat
gaaactggagaagttgtcaatgaaaaggccaagacccatgttcttgacattgagcagcga
ctacaaggtgtaatcaagactcgaaatagagtgacaggactgccgttatctattgaagga
catgtgcattaccttatacaagaagctactgatgaaaacttactatgccagatgtatctt
ggttggactccatatatgtga

  All links  
Ontology (4)   
   KEGG BRITE (4)   
Pathway (7)   
   KEGG PATHWAY (7)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (6)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
   VGNC (1)   
Protein sequence (5)   
   UniProt (1)   
   RefSeq(pep) (4)   
DNA sequence (16)   
   RefSeq(nuc) (6)   
   GenBank (5)   
   EMBL (5)   
Protein domain (9)   
   Pfam (9)   
All databases (49)   

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