KEGG   Pan troglodytes (chimpanzee): 462770Help
Entry
462770            CDS       T01005                                 

Gene name
GSTA3
Definition
(RefSeq) glutathione S-transferase A3 isoform X1
  KO
K00799  glutathione S-transferase [EC:2.5.1.18]
Organism
ptr  Pan troglodytes (chimpanzee)
Pathway
ptr00480  Glutathione metabolism
ptr00980  Metabolism of xenobiotics by cytochrome P450
ptr00982  Drug metabolism - cytochrome P450
ptr00983  Drug metabolism - other enzymes
ptr01100  Metabolic pathways
ptr01524  Platinum drug resistance
ptr05200  Pathways in cancer
ptr05204  Chemical carcinogenesis
ptr05225  Hepatocellular carcinoma
ptr05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:ptr00001]
 09100 Metabolism
  09106 Metabolism of other amino acids
   00480 Glutathione metabolism
    462770 (GSTA3)
  09111 Xenobiotics biodegradation and metabolism
   00980 Metabolism of xenobiotics by cytochrome P450
    462770 (GSTA3)
   00982 Drug metabolism - cytochrome P450
    462770 (GSTA3)
   00983 Drug metabolism - other enzymes
    462770 (GSTA3)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    462770 (GSTA3)
   05204 Chemical carcinogenesis
    462770 (GSTA3)
  09162 Cancer: specific types
   05225 Hepatocellular carcinoma
    462770 (GSTA3)
  09166 Cardiovascular disease
   05418 Fluid shear stress and atherosclerosis
    462770 (GSTA3)
  09176 Drug resistance: antineoplastic
   01524 Platinum drug resistance
    462770 (GSTA3)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   02000 Transporters [BR:ptr02000]
    462770 (GSTA3)
Enzymes [BR:ptr01000]
 2. Transferases
  2.5  Transferring alkyl or aryl groups, other than methyl groups
   2.5.1  Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)
    2.5.1.18  glutathione transferase
     462770 (GSTA3)
Transporters [BR:ptr02000]
 Other transporters
  Pores ion channels [TC:1]
   462770 (GSTA3)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: GST_C_3 GST_C GST_N DUF3825
Motif
Other DBs
NCBI-GeneID: 462770
NCBI-ProteinID: XP_016811161
Ensembl: ENSPTRG00000018284
VGNC: 11091
UniProt: H2QT71
Position
6
AA seq 172 aa AA seqDB search
MFQQVPMVEIDGMKLVQTRAILNYIASKYNLYGKDIKERALIDMYTEGMADLNEMILLLP
LCRPEEKDAKIALIKEKTKSRYFPAFEKVLQSHGQDYLVGNKLSRADISLVELLYYVEEL
DSSLISSFPLLKALKTRISNLPTVKKFLQPGSPRKPPADAKALEEARKIFRF
NT seq 519 nt NT seq  +upstreamnt  +downstreamnt
atgttccagcaagtaccaatggttgagattgatgggatgaagttggtacagaccagagcc
attctcaactacattgccagcaaatacaacctctacgggaaagacataaaggagagagcc
ctaattgatatgtatacagaaggtatggcagatttgaatgaaatgatccttcttctgccc
ttatgtcgacctgaggaaaaagatgccaagattgccttgatcaaagagaaaacaaaaagt
cgctatttccctgccttcgaaaaagtgttacagagccatggacaagactaccttgttggc
aacaagctgagccgggctgacattagcctggtggaacttctctactatgtggaagagctt
gactccagccttatctccagcttccctctgctgaaggccctgaaaaccagaatcagcaac
ctgcccacagtgaagaagtttctacagcctggcagcccaaggaaacctcccgcagatgca
aaagctttagaagaagccagaaagattttcaggttttaa

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