GenomeNet

Database: PubMed
Entry: 271964
LinkDB: 271964
Original site: 271964 
PMID:
     271964
Authors:
     Anderson L, Anderson NG.
Title:
     High resolution two-dimensional electrophoresis of human plasma proteins.
Journal:
     Proc Natl Acad Sci U S A. 1977 Dec;74(12):5421-5. doi: 10.1073/pnas.74.12.5421.
Abstract:
     The two-dimensional electrophoretic technique of O'Farrell has been adapted to
     the analysis of human plasma proteins, and 30 polypeptides have been identified
     in the pattern produced. Genetic variants involving charge (isoelectric point) or
     size (molecular weight in the presence of sodium dodecyl sulfate) changes should 
     be routinely detectable in at least 20 proteins at once, facilitating studies of 
     human mutation rates.

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