KEGG   Rousettus aegyptiacus (Egyptian rousette): 107521615Help
Entry
107521615         CDS       T06036                                 

Gene name
PLA2G4A
Definition
(RefSeq) cytosolic phospholipase A2
  KO
K16342  cytosolic phospholipase A2 [EC:3.1.1.4]
Organism
ray  Rousettus aegyptiacus (Egyptian rousette)
Pathway
ray00564  Glycerophospholipid metabolism
ray00565  Ether lipid metabolism
ray00590  Arachidonic acid metabolism
ray00591  Linoleic acid metabolism
ray00592  alpha-Linolenic acid metabolism
ray01100  Metabolic pathways
ray04010  MAPK signaling pathway
ray04014  Ras signaling pathway
ray04072  Phospholipase D signaling pathway
ray04217  Necroptosis
ray04270  Vascular smooth muscle contraction
ray04370  VEGF signaling pathway
ray04611  Platelet activation
ray04664  Fc epsilon RI signaling pathway
ray04666  Fc gamma R-mediated phagocytosis
ray04724  Glutamatergic synapse
ray04726  Serotonergic synapse
ray04730  Long-term depression
ray04750  Inflammatory mediator regulation of TRP channels
ray04912  GnRH signaling pathway
ray04913  Ovarian steroidogenesis
ray04921  Oxytocin signaling pathway
ray05231  Choline metabolism in cancer
Brite
KEGG Orthology (KO) [BR:ray00001]
 09100 Metabolism
  09103 Lipid metabolism
   00564 Glycerophospholipid metabolism
    107521615 (PLA2G4A)
   00565 Ether lipid metabolism
    107521615 (PLA2G4A)
   00590 Arachidonic acid metabolism
    107521615 (PLA2G4A)
   00591 Linoleic acid metabolism
    107521615 (PLA2G4A)
   00592 alpha-Linolenic acid metabolism
    107521615 (PLA2G4A)
 09130 Environmental Information Processing
  09132 Signal transduction
   04014 Ras signaling pathway
    107521615 (PLA2G4A)
   04010 MAPK signaling pathway
    107521615 (PLA2G4A)
   04370 VEGF signaling pathway
    107521615 (PLA2G4A)
   04072 Phospholipase D signaling pathway
    107521615 (PLA2G4A)
 09140 Cellular Processes
  09143 Cell growth and death
   04217 Necroptosis
    107521615 (PLA2G4A)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    107521615 (PLA2G4A)
   04664 Fc epsilon RI signaling pathway
    107521615 (PLA2G4A)
   04666 Fc gamma R-mediated phagocytosis
    107521615 (PLA2G4A)
  09152 Endocrine system
   04912 GnRH signaling pathway
    107521615 (PLA2G4A)
   04913 Ovarian steroidogenesis
    107521615 (PLA2G4A)
   04921 Oxytocin signaling pathway
    107521615 (PLA2G4A)
  09153 Circulatory system
   04270 Vascular smooth muscle contraction
    107521615 (PLA2G4A)
  09156 Nervous system
   04724 Glutamatergic synapse
    107521615 (PLA2G4A)
   04726 Serotonergic synapse
    107521615 (PLA2G4A)
   04730 Long-term depression
    107521615 (PLA2G4A)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    107521615 (PLA2G4A)
 09160 Human Diseases
  09161 Cancer: overview
   05231 Choline metabolism in cancer
    107521615 (PLA2G4A)
Enzymes [BR:ray01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.1  Carboxylic-ester hydrolases
    3.1.1.4  phospholipase A2
     107521615 (PLA2G4A)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: PLA2_B C2
Motif
Other DBs
NCBI-GeneID: 107521615
NCBI-ProteinID: XP_016021941
Position
Unknown
AA seq 741 aa AA seqDB search
MFLVEHQYSHKFTVVVLRATKVTKGAFGDMLDTPDPYVELFISSTPDSRKRTRHFNNDIN
PVWNETFEFILDPNQENVLEITLMDANYVMDETLGTATFPISFMKVGEKKEVPFIFNEVT
EMILEMSLEVCSSPDLRFSMALCDQEKAFRYRRKENIRENMKKLLGPENSEGLSSTRDVP
VVAILGSGGGFRAMVGFSGVMKALYESGILDCTTYVAGLSGSTWYMSTLYSHPDFPEKGP
EEINEELMKNVSYNPLLLLTPQKVKRYVESLWKKKRSGQPVTFTDIFGMLIGETLIHNRM
NITLSSLKEKVNTAQCPLPLFTCLHVKPDVSELMFADWVEFSPYEIGMAKYGTFMAPDLF
GSKFFMGKVVKKYEENPLHFLMGVWGSAFSILFNRVLGVSSSQNKGSTMEEELENITAKH
IVSNDSSDSDDESQEPKGTENEDAERDYQNDNQASWVHRMIMALMSDSALFNTREGRAGK
VHNFMLGLNLNTSYPLSPFRDFTTQESLDEDELDAAVADPDEFEQIYEPLDVKSKKIHVV
DSGLTFNLPYPLILRPQRGVDLIISFDFSARPSDSSPPFKELLLAEKWAKMNKLPFPKID
PYVFDREGLKECYVFKPKNPDVEKDCPTIIHFVLANINFRKYKAPGVPRETTEEKEIADF
DIFDDPESPFSTFNFQYPNQAFKRLHDLMYFNTLNNIDVIKNAIIESIEYRRQNPSRCSV
SLSNIEARKFFNKEALSKPTA
NT seq 2226 nt NT seq  +upstreamnt  +downstreamnt
atgtttctagtggagcaccagtattcccacaagttcacagtagtggtgttacgtgccacc
aaagtgacaaagggggccttcggtgacatgcttgacactccagacccctacgtggaactt
ttcatctcctcaactcccgacagcaggaagagaacgagacactttaataatgacataaac
cctgtgtggaatgagacctttgaatttattttggacccgaatcaggaaaatgttttggag
atcacgttaatggatgccaattatgtcatggatgaaactcttggaacagcaacgtttccc
atatcttttatgaaagtaggagagaagaaagaggttccttttattttcaacgaagtcact
gaaatgatcctggaaatgtcccttgaagtttgctcatccccagacctccgatttagcatg
gctctgtgtgatcaggagaaagctttcaggtaccggaggaaagaaaacatcagggaaaac
atgaagaaactcctgggtccggagaacagcgaaggcttgtcttctacacgcgatgtacct
gtggtcgccatactgggctcaggtggagggtttcgagccatggtaggattctccggcgtg
atgaaggcactgtatgaatcaggaattttggattgcactacttatgttgctggtctttct
ggctccacatggtacatgtcaaccttatattctcaccctgattttccagagaaagggcca
gaggagattaatgaagagctaatgaaaaatgttagctataacccccttttacttctcaca
ccacagaaagttaagagatatgttgagtctttatggaagaagaaaaggtctggacaacct
gtcacctttacggatatctttggaatgttaataggagaaacactaattcacaatagaatg
aacattaccttgagtagtttgaaggaaaaagtcaatactgcacaatgccctttacctctt
ttcacctgtctgcatgtcaaacctgatgtttcagaactgatgtttgcagattgggttgaa
tttagtccgtatgagattggcatggctaaatacggtacttttatggctcctgacttattt
ggaagcaaattttttatgggaaaagttgtgaagaaatacgaagaaaaccccttgcatttc
ctaatgggtgtctggggcagcgccttttctatattgttcaacagagtcttgggagtttcc
agttcacaaaataaaggttccaccatggaggaagaattagaaaacattacggcaaagcat
attgtgagtaatgatagctcagatagcgatgatgaatcacaagaacccaaaggcactgaa
aatgaagatgccgaaagagactatcaaaatgataatcaagcaagttgggtccatcgtatg
ataatggccttgatgagcgattcagctctattcaataccagagaaggacgtgctgggaag
gttcacaacttcatgctgggcttgaatctcaatacatcttatccactgtctcctttcaga
gacttcaccacacaggagtccttggatgaagatgaacttgatgcagctgtagcagatcct
gatgaatttgagcaaatatatgagcctctggatgtcaaaagtaaaaagattcacgtagta
gacagtggcctcacatttaacctaccttatcccttgatcctgagacctcagaggggagtt
gatctcatcatctcctttgacttttctgcaagaccaagtgactctagtcctccgttcaag
gaacttctacttgcagaaaaatgggctaaaatgaacaagcttccctttccaaagattgac
ccttatgtgtttgatcgagaaggactaaaggagtgttatgtctttaaacccaagaatcct
gatgtagagaaagattgcccgacgatcattcacttcgttctggccaacatcaacttcaga
aagtacaaggctccaggtgttccaagagaaactacagaagagaaagaaatagctgatttt
gatatttttgatgacccggaatcaccgttttcaaccttcaacttccaatatccaaatcaa
gcattcaaaaggctgcatgatctgatgtacttcaacaccctgaacaacatcgatgtaata
aagaatgccatcattgaaagcatcgaatacagaaggcagaatccatctcgctgttctgtt
tccctcagtaacattgaggcaagaaaatttttcaacaaggaggctctaagcaaacccaca
gcataa

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