KEGG   Rhinopithecus bieti (black snub-nosed monkey): 108523215
Entry
108523215         CDS       T04641                                 
Symbol
MAP2K6
Name
(RefSeq) dual specificity mitogen-activated protein kinase kinase 6 isoform X1
  KO
K04433  mitogen-activated protein kinase kinase 6 [EC:2.7.12.2]
Organism
rbb  Rhinopithecus bieti (black snub-nosed monkey)
Pathway
rbb04010  MAPK signaling pathway
rbb04015  Rap1 signaling pathway
rbb04218  Cellular senescence
rbb04380  Osteoclast differentiation
rbb04620  Toll-like receptor signaling pathway
rbb04664  Fc epsilon RI signaling pathway
rbb04668  TNF signaling pathway
rbb04750  Inflammatory mediator regulation of TRP channels
rbb04912  GnRH signaling pathway
rbb04935  Growth hormone synthesis, secretion and action
rbb04936  Alcoholic liver disease
rbb05014  Amyotrophic lateral sclerosis
rbb05022  Pathways of neurodegeneration - multiple diseases
rbb05132  Salmonella infection
rbb05135  Yersinia infection
rbb05145  Toxoplasmosis
rbb05161  Hepatitis B
rbb05163  Human cytomegalovirus infection
rbb05167  Kaposi sarcoma-associated herpesvirus infection
rbb05169  Epstein-Barr virus infection
rbb05170  Human immunodeficiency virus 1 infection
rbb05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
rbb05417  Lipid and atherosclerosis
rbb05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:rbb00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    108523215 (MAP2K6)
   04015 Rap1 signaling pathway
    108523215 (MAP2K6)
   04668 TNF signaling pathway
    108523215 (MAP2K6)
 09140 Cellular Processes
  09143 Cell growth and death
   04218 Cellular senescence
    108523215 (MAP2K6)
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    108523215 (MAP2K6)
   04664 Fc epsilon RI signaling pathway
    108523215 (MAP2K6)
  09152 Endocrine system
   04912 GnRH signaling pathway
    108523215 (MAP2K6)
   04935 Growth hormone synthesis, secretion and action
    108523215 (MAP2K6)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    108523215 (MAP2K6)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    108523215 (MAP2K6)
 09160 Human Diseases
  09161 Cancer: overview
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    108523215 (MAP2K6)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    108523215 (MAP2K6)
   05161 Hepatitis B
    108523215 (MAP2K6)
   05163 Human cytomegalovirus infection
    108523215 (MAP2K6)
   05167 Kaposi sarcoma-associated herpesvirus infection
    108523215 (MAP2K6)
   05169 Epstein-Barr virus infection
    108523215 (MAP2K6)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    108523215 (MAP2K6)
   05135 Yersinia infection
    108523215 (MAP2K6)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    108523215 (MAP2K6)
  09164 Neurodegenerative disease
   05014 Amyotrophic lateral sclerosis
    108523215 (MAP2K6)
   05022 Pathways of neurodegeneration - multiple diseases
    108523215 (MAP2K6)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    108523215 (MAP2K6)
   05418 Fluid shear stress and atherosclerosis
    108523215 (MAP2K6)
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    108523215 (MAP2K6)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:rbb01001]
    108523215 (MAP2K6)
Enzymes [BR:rbb01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.12  Dual-specificity kinases (those acting on Ser/Thr and Tyr residues)
    2.7.12.2  mitogen-activated protein kinase kinase
     108523215 (MAP2K6)
Protein kinases [BR:rbb01001]
 Serine/threonine kinases: STE group
  STE7 family
   108523215 (MAP2K6)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr Kinase-like ABC1 Seadorna_VP7 Pkinase_fungal Haspin_kinase DUF4344 Choline_kinase APH
Other DBs
NCBI-GeneID: 108523215
NCBI-ProteinID: XP_017719217
UniProt: A0A2K6LB21
Position
Unknown
AA seq 334 aa
MSQSKGKKRNPGLKIPKEAFEQPQTSSTPPRDLDSKACISIGNQNFEVKADDLEPIMELG
RGAYGVVEKMRHVPSGQIMAVKRIRATVNSQEQKRLLMDLDISMRTVDCPFTVTFYGALF
REGDVWICMELMDTSLDKFYKQVIDKGQTIPEDILGKIAVSIVKALEHLHSKLSVIHRDV
KPSNVLINALGQVKMCDFGISGYLVDSVAKTIDAGCKPYMAPERINPELNQKGYSVKSDI
WSLGITMIELAILRFPYDSWGTPFQQLKQVVEEPSPQLPADKFSAEFVDFTSQCLKKNSK
ERPTYPELMQHPFFTLHESKGTDVASFVKLILGD
NT seq 1005 nt   +upstreamnt  +downstreamnt
atgtctcagtcgaaaggcaagaagcgaaaccctggccttaaaattccaaaagaagcgttt
gaacaacctcagaccagttccacaccacctcgagatttagactccaaggcttgcatttct
attggaaatcagaactttgaggtgaaggcagatgacctggagcctataatggaactggga
cgaggtgcgtacggggtggtggagaagatgcggcacgtgcccagcgggcagatcatggca
gtgaagcggatccgagccacagtaaatagccaggaacagaaaaggctactgatggatttg
gatatttccatgaggacggtggactgtccattcaccgtcaccttttatggcgcactgttt
cgggagggtgatgtgtggatctgcatggagctcatggatacatcactagataaattctac
aaacaagttattgataaaggccagacaattccagaggacatcttagggaaaatagcagtt
tctattgtaaaagcattagaacatttacacagtaagctgtctgtcattcacagagacgtc
aagccttctaatgtactcattaatgctctcggtcaagtgaagatgtgcgattttggaatc
agtggctacttggtggactctgttgctaaaacgattgatgcgggttgcaaaccatacatg
gcccctgaaagaataaacccagagctcaaccagaagggatacagtgtgaagtctgacatt
tggagcctaggcatcacaatgattgagttggccatccttcgatttccctatgattcatgg
ggaactccatttcagcagctcaaacaggtggtagaggagccatcgccacaactcccagca
gacaagttctctgcagagttcgttgactttacctcacagtgcttaaagaagaattccaaa
gaacggcctacatacccagagctaatgcaacatccatttttcactctacatgaatccaaa
ggaacagatgtggcatcttttgtaaaactgattcttggagactaa

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Ontology (3)   
   KEGG BRITE (3)   
Pathway (24)   
   KEGG PATHWAY (24)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (4)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   OC (1)   
Protein sequence (4)   
   UniProt (1)   
   RefSeq(pep) (3)   
DNA sequence (3)   
   RefSeq(nuc) (3)   
Protein domain (10)   
   Pfam (10)   
All databases (50)   

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