KEGG   Rhinopithecus bieti (black snub-nosed monkey): 108523688
Entry
108523688         CDS       T04641                                 
Symbol
ATP2A1
Name
(RefSeq) sarcoplasmic/endoplasmic reticulum calcium ATPase 1
  KO
K05853  P-type Ca2+ transporter type 2A [EC:7.2.2.10]
Organism
rbb  Rhinopithecus bieti (black snub-nosed monkey)
Pathway
rbb04020  Calcium signaling pathway
rbb04022  cGMP-PKG signaling pathway
rbb04024  cAMP signaling pathway
rbb04148  Efferocytosis
rbb04260  Cardiac muscle contraction
rbb04261  Adrenergic signaling in cardiomyocytes
rbb04380  Osteoclast differentiation
rbb04919  Thyroid hormone signaling pathway
rbb04972  Pancreatic secretion
rbb05010  Alzheimer disease
rbb05017  Spinocerebellar ataxia
rbb05022  Pathways of neurodegeneration - multiple diseases
rbb05410  Hypertrophic cardiomyopathy
rbb05412  Arrhythmogenic right ventricular cardiomyopathy
rbb05414  Dilated cardiomyopathy
rbb05415  Diabetic cardiomyopathy
Brite
KEGG Orthology (KO) [BR:rbb00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04020 Calcium signaling pathway
    108523688 (ATP2A1)
   04024 cAMP signaling pathway
    108523688 (ATP2A1)
   04022 cGMP-PKG signaling pathway
    108523688 (ATP2A1)
 09140 Cellular Processes
  09141 Transport and catabolism
   04148 Efferocytosis
    108523688 (ATP2A1)
 09150 Organismal Systems
  09152 Endocrine system
   04919 Thyroid hormone signaling pathway
    108523688 (ATP2A1)
  09153 Circulatory system
   04260 Cardiac muscle contraction
    108523688 (ATP2A1)
   04261 Adrenergic signaling in cardiomyocytes
    108523688 (ATP2A1)
  09154 Digestive system
   04972 Pancreatic secretion
    108523688 (ATP2A1)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    108523688 (ATP2A1)
 09160 Human Diseases
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    108523688 (ATP2A1)
   05017 Spinocerebellar ataxia
    108523688 (ATP2A1)
   05022 Pathways of neurodegeneration - multiple diseases
    108523688 (ATP2A1)
  09166 Cardiovascular disease
   05410 Hypertrophic cardiomyopathy
    108523688 (ATP2A1)
   05412 Arrhythmogenic right ventricular cardiomyopathy
    108523688 (ATP2A1)
   05414 Dilated cardiomyopathy
    108523688 (ATP2A1)
   05415 Diabetic cardiomyopathy
    108523688 (ATP2A1)
Enzymes [BR:rbb01000]
 7. Translocases
  7.2  Catalysing the translocation of inorganic cations
   7.2.2  Linked to the hydrolysis of a nucleoside triphosphate
    7.2.2.10  P-type Ca2+ transporter
     108523688 (ATP2A1)
SSDB
Motif
Pfam: E1-E2_ATPase Cation_ATPase_C Cation_ATPase Cation_ATPase_N Hydrolase Hydrolase_3 HAD
Other DBs
NCBI-GeneID: 108523688
NCBI-ProteinID: XP_017719911
Position
Unknown
AA seq 994 aa
MEAAHAKTTEECLAYFGVSETTGLTPDQVKRNLEKYGPNELPAEEGKTLWELVIEQFEDL
LVRILLLAACISFVLAWFEEGEETITAFVEPFVILLILIANAIVGVWQERNAENAIEALK
EYEPEMGKVYRADRKAVQRIKARDIVPGDIVEVAVGDKVPADIRILAIKSTTLRVDQSIL
TGESVSVIKHTEPVPDPRAVNQDKKNMLFSGTNIAAGKALGIVATTGVSTEIGKIRDQMA
ATEQDKTPLQQKLDEFGEQLSKVISLICVAVWLINIGHFNDPVHGGSWIRGAIYYFKIAV
ALAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQ
MSVCKMFIIDKVDGDICLLNEFSITGSTYAPEGEVLKNDKPVRPGQYDGLVELATICALC
NDSSLDFNEAKGVYEKVGEATETALTTLVEKMNVFNTDVRNLSKVERANACNSVIRQLMK
KEFTLEFSRDRKSMSVYCSPAKSSRAAVGNKMFVKGAPEGVIDRCNYVRVGTTRVPLTGP
VKEKIMAVIKEWGTGRDTLRCLALATRDTPPKREEMILDDSARFLEYETDLTFVGVVGML
DPPRKEVMGSIQLCRDAGIRVIMITGDNKGTAIAICRRIGIFGENEEVADRAYTGREFDD
LPLPEQREACRRACCFARVEPSHKSKIVEYLQSFDEITAMTGDGVNDAPALKKAEIGIAM
GSGTAVAKTASEMVLADDNFSTIVAAVEEGRAIYNNMKQFIRYLISSNVGEVVCIFLTAA
LGLPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMDRPPRSPKEPLISGWLFFRYMAI
GGYVGAATVGAAAWWFMYAEDGPHVNYSQLTHFMQCTEDNAHFEGIDCEVFEASEPMTMA
LSVLVTIEMCNALNSLSENQSLLRMPPWVNIWLVGSICLSMSLHFLILYVDPLPMIFKLQ
ALDLAHWLMVLKISLPVIGLDEILKFIARNYLEG
NT seq 2985 nt   +upstreamnt  +downstreamnt
atggaggccgctcacgctaaaaccacggaggaatgtttggcctattttggggtgagtgag
accacgggcctcaccccggaccaagttaagcggaatctggagaaatacggccccaatgag
ctccctgctgaggaagggaagaccctgtgggagctggtgatagagcagtttgaagacctc
ctggtgcggatcctcctcctggccgcatgcatttccttcgtgctggcctggtttgaggaa
ggtgaagagaccatcactgcctttgttgaaccttttgtcatcctcttgatcctcattgcc
aatgccatcgtgggggtttggcaggagcggaacgcagagaatgccatagaggccctgaag
gagtatgagccagagatggggaaggtctaccgggctgaccgcaaggcagtgcaaaggatc
aaggctcgggacatcgtccccggggacatcgtggaggtggctgtgggagacaaagtccct
gcagacatccgaatcctcgccatcaaatccaccaccctgcgggttgaccagtccatcctg
acaggcgagtctgtatctgtcatcaagcacacggagcccgttcctgacccccgagctgtc
aaccaggacaagaagaacatgcttttctcgggcaccaacattgcagctggcaaggccttg
ggcattgtggccaccaccggtgtgagcactgagattgggaaaatccgagaccaaatggct
gccacagaacaggacaagacccctttgcagcagaagctggatgagtttggggagcagctc
tccaaggtcatctccctcatctgtgtggctgtctggctcatcaacattggccacttcaat
gaccctgtccatgggggctcctggatccgcggggccatctactactttaagattgccgtg
gccttggctgtggctgccatccccgaaggtcttcctgcagtcatcaccacctgcctggcc
ctgggtacccgccggatggcaaagaagaatgccattgtaaggagcttgccctccgtagag
accctgggctgcacctctgtcatctgttccgacaagacaggcaccctcaccaccaaccag
atgtctgtctgcaagatgtttatcattgataaggtggatggggacatctgcctcctgaat
gagttctccatcactggctccacttacgctccagagggagaggtcttgaagaatgataag
ccagtccggccagggcagtatgacgggctggtggagctggccaccatctgtgccctctgc
aatgactcctccttggacttcaacgaggccaaaggtgtctatgagaaggttggcgaggcc
accgagacagcactcaccaccctggtggagaagatgaatgtattcaacacagatgtgaga
aacctctcgaaggtggagagagccaacgcctgcaactcggtgatccgccagctaatgaag
aaggaattcaccctggagttctcccgagacaggaagtccatgtctgtctattgctcccca
gccaaatcttcccgggctgctgtgggcaacaagatgtttgtcaagggtgcccccgagggc
gtcatcgaccgctgtaactatgtgcgagttggcaccacccgggtgccactgacggggcca
gtgaaggagaagatcatggcagtgatcaaggagtggggcactggccgggacactctgcgc
tgcttggccctggccacaagggacacccccccgaagcgagaggaaatgatcctggatgac
tctgccaggttcctagaatatgagacggacctgacattcgtgggcgtggtgggcatgctg
gaccctccacgcaaggaggtcatgggctccatccagctgtgccgtgacgctgggatccgg
gtgatcatgatcactggggacaacaagggcacagccattgccatctgccggcgaattggc
atctttggggagaacgaggaggtggccgatcgcgcctacacgggccgagagttcgatgac
ctgcctctgcctgaacagcgggaagcctgccgacgtgcctgctgctttgcccgcgtggag
ccctcacacaagtccaagattgtggagtacctgcagtccttcgatgagatcacagccatg
acaggtgatggcgtcaatgacgcccctgccctgaagaaggccgagattggcattgccatg
ggatctggcactgctgtggccaagactgcctctgagatggtgctggccgacgacaacttc
tccaccatcgtagctgctgtggaggagggccgcgccatctataacaacatgaagcagttc
atccgctacctcatttcctccaacgtgggcgaggtggtctgcatcttcctgactgctgcc
ctggggctgcccgaggccctgatcccggtgcagctgctgtgggtgaacttggtgaccgac
gggctcccagccacagccctgggcttcaacccaccagacctggacatcatggaccgcccc
ccccggagccccaaggagcctctcatcagtggctggctcttcttccgctacatggcaatc
gggggctatgtgggtgcagccaccgtgggagcggctgcctggtggttcatgtacgctgag
gacgggcctcatgtcaactacagccagctgactcacttcatgcagtgcaccgaggacaac
gcccacttcgagggcatagactgtgaggtcttcgaggcctctgagcccatgaccatggcc
ttgtccgtgctggtgaccatcgagatgtgcaacgcactcaacagcctgtccgagaaccag
tccctgctgcggatgccaccctgggtgaacatctggctggtgggctccatctgcctctcc
atgtccctgcacttcctcatcctctacgttgaccccctgccgatgatcttcaagctccag
gccctggacctcgcccactggctcatggtcctcaagatctcactgccggtcattgggctc
gacgaaatcctcaagttcattgctcggaactacctagagggataa

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