KEGG   Rhinopithecus bieti (black snub-nosed monkey): 108533749
Entry
108533749         CDS       T04641                                 
Symbol
KIT
Name
(RefSeq) mast/stem cell growth factor receptor Kit isoform X1
  KO
K05091  proto-oncogene tyrosine-protein kinase Kit [EC:2.7.10.1]
Organism
rbb  Rhinopithecus bieti (black snub-nosed monkey)
Pathway
rbb04010  MAPK signaling pathway
rbb04014  Ras signaling pathway
rbb04015  Rap1 signaling pathway
rbb04072  Phospholipase D signaling pathway
rbb04151  PI3K-Akt signaling pathway
rbb04640  Hematopoietic cell lineage
rbb04916  Melanogenesis
rbb05200  Pathways in cancer
rbb05221  Acute myeloid leukemia
rbb05224  Breast cancer
rbb05230  Central carbon metabolism in cancer
Brite
KEGG Orthology (KO) [BR:rbb00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    108533749 (KIT)
   04014 Ras signaling pathway
    108533749 (KIT)
   04015 Rap1 signaling pathway
    108533749 (KIT)
   04072 Phospholipase D signaling pathway
    108533749 (KIT)
   04151 PI3K-Akt signaling pathway
    108533749 (KIT)
 09150 Organismal Systems
  09151 Immune system
   04640 Hematopoietic cell lineage
    108533749 (KIT)
  09152 Endocrine system
   04916 Melanogenesis
    108533749 (KIT)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    108533749 (KIT)
   05230 Central carbon metabolism in cancer
    108533749 (KIT)
  09162 Cancer: specific types
   05221 Acute myeloid leukemia
    108533749 (KIT)
   05224 Breast cancer
    108533749 (KIT)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:rbb01001]
    108533749 (KIT)
  09183 Protein families: signaling and cellular processes
   04090 CD molecules [BR:rbb04090]
    108533749 (KIT)
Enzymes [BR:rbb01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.10  Protein-tyrosine kinases
    2.7.10.1  receptor protein-tyrosine kinase
     108533749 (KIT)
Protein kinases [BR:rbb01001]
 Receptor tyrosine kinases (RTK)
  PDGFR family [OT]
   108533749 (KIT)
CD molecules [BR:rbb04090]
 Proteins
  108533749 (KIT)
SSDB
Motif
Pfam: PK_Tyr_Ser-Thr Pkinase Ig_3 ig I-set Ig_2 V-set Ig_6
Other DBs
NCBI-GeneID: 108533749
NCBI-ProteinID: XP_017734133
Position
Unknown
AA seq 976 aa
MRGARGAWDFLCVLLFLLHVQTGSSQPSVSPGEPSPPSIHPAKSELIVHVGNEIRLLCID
PGFVKWTFEILDETNENKQNEWITEKAEATNTGKYTCTNKHGLSSSIYVFVRDPAKLFLV
DRSLYGKEDNDTLVRCPLTDPEVTSYSLKGCQGKPLPKDLRFVPDPKAGITIKSVKRAYH
RLCLHCSADQEGKSVLSDKFILKVRPAFKAVPVVSVSKASYLLREGEEFTVTCTIKDVSS
SVYSTWKRENSQTKLQEKYNSWHHGDFNYERQATLTISSARVNDSGVFMCYANNTFGSAN
VTTTLEVVDKGFINIFPMINTTVFVNDGENVDLIVEYEAFPKPEHQQWIYMNRTFTDKWE
DYPKSENESNIRYVSELHLTRLKGTEGGTYTFLVSNSDVNASIAFNVYVNTKPEILTYDR
LVNGMLQCVAAGFPEPTIDWYFCPGTEQRCSASVLPVDVQTLNASGPPFGKLVVQSSIDS
SAFKHNGTVECKAYNDVGKTSAYFNFAFKGNNKEQIHPHTLFTPLLIGFVIVAGMMCIIV
MILTYKYLQKPMYEVQWKVVEEINGNNYVYIDPTQLPYDHKWEFPRNRLSFGKTLGAGAF
GKVVEATAYGLIKSDAAMTVAVKMLKPSAHLTEREALMSELKVLSYLGNHMNIVNLLGAC
TIGGPTLVITEYCCYGDLLNFLRRKRDSFICSKQEDHAETALYKNLLHSKESSCSDSTNE
YMDMKPGVSYVVPTKADKRRSARIGSYIERDVTPAIMEDDELALDLEDLLSFSYQVAKGM
AFLASKNCIHRDLAARNILLTHGRITKICDFGLARDIKNDSNYVVKGNARLPVKWMAPES
IFNCVYTFESDVWSYGIFLWELFSLGSSPYPGMPVDSKFYKMIKEGFRMLSPEHAPAEMY
DIMKTCWDADPLKRPTFKQIVQLIEKQISESTNHIYSNLANCSPNRQKPVVDHSVRINSV
GSTASSSQPLLVHDDV
NT seq 2931 nt   +upstreamnt  +downstreamnt
atgagaggcgctcgcggcgcctgggattttctctgcgttctgctcttcctgctccacgtc
cagacaggctcttctcaaccatctgtgagtccaggggaaccgtctccaccatccatccat
ccagcaaaatcagagttaatagtccacgtgggcaacgagattaggctgttgtgcattgat
ccaggctttgtcaaatggacttttgagatcctggatgaaacgaatgagaataagcagaat
gaatggatcacagaaaaggcagaggccaccaacactggcaaatacacatgcaccaacaaa
cacggcttaagcagttccatttatgtgtttgttagagatcctgccaagcttttccttgtt
gaccgctccttgtatggtaaagaagacaatgacacactggtccgctgtcctctcacagac
ccagaagtgaccagttattccctcaaggggtgccaggggaagcctcttcccaaggacttg
aggtttgttcctgaccccaaggctggcatcacgatcaaaagtgtgaaacgcgcctaccat
cggctctgtctgcattgttctgcggaccaggagggcaagtcagtgctgtcagacaaattc
atcctgaaagtgaggccagccttcaaagctgtgcctgttgtgtctgtgtccaaagcaagc
tatcttcttagggaaggcgaagaattcacagtgacgtgcacaataaaagatgtgtctagt
tctgtgtactcaacgtggaaaagggaaaacagtcagactaaactacaggagaaatataat
agctggcatcacggtgacttcaattatgaacgtcaggcaacgctgactatcagttcagcg
agagttaatgattctggagtgttcatgtgttatgccaataatacttttggatcagcaaat
gtcacaacaaccttggaagtagtagataaaggattcattaatatcttccccatgataaac
actacagtatttgtaaatgatggagaaaatgtagatttgattgttgaatatgaggcattc
cccaaacctgaacaccagcagtggatctatatgaacagaaccttcactgataaatgggaa
gattatcccaagtctgagaatgaaagtaatatcagatacgtaagtgaacttcatctaacc
agattaaaaggcactgaaggaggcacatacacattcctagtgtccaattctgacgtcaat
gcttccatagcatttaatgtttatgtgaatacaaaaccagaaatcctgacttacgacagg
ctcgtgaatggcatgctccaatgtgtggcagcaggattcccagaacccacaatagattgg
tatttttgtccgggaactgagcagagatgctctgcttctgtactgccagtggatgtgcag
acactaaacgcatctgggccaccatttggaaaactagtggttcagagctccatagattct
agtgcattcaagcacaatggcacggttgaatgtaaggcttacaacgatgtgggcaagact
tctgcctattttaactttgcatttaaaggtaacaacaaagagcaaatccatccccacacc
ctgttcactcctttgctgattggttttgtaatcgtagctggcatgatgtgcattattgtg
atgattctaacctacaaatatttacagaaacccatgtatgaagtacagtggaaggttgtt
gaggagataaatggaaacaattacgtttacatagacccaacacaacttccttatgatcac
aaatgggagtttcccagaaacaggctgagttttgggaaaaccctgggtgctggcgctttc
gggaaggttgttgaggcaactgcttatggcttaattaagtcggacgcggccatgactgtc
gctgtaaagatgctcaaaccaagtgcccatttaacagaacgagaagccctcatgtctgaa
ctcaaagtcctgagttaccttggtaatcatatgaatattgtgaatcttcttggagcctgc
accattggagggcccaccctggtcattacagaatattgttgctatggtgatcttttgaat
tttttgagaagaaaacgtgattcttttatttgttcaaagcaggaagatcatgcagaaact
gcactttataagaatcttctgcattcaaaggagtcttcctgcagcgatagtactaatgag
tacatggacatgaaacctggagtttcttatgttgtcccaaccaaggctgacaaaaggaga
tctgcgagaataggctcatacatagaaagagatgtgactcccgccatcatggaggatgac
gagttggccctagacttagaagacttgctgagcttttcttaccaggtggcaaagggcatg
gctttccttgcctccaagaattgtattcacagagacttggcagccagaaatatcctcctt
actcatggtcggatcacaaagatttgtgattttggtctagccagagacatcaagaatgat
tctaattatgtggttaaaggaaacgctcgactacctgtgaagtggatggcacctgaaagc
attttcaattgtgtatacacgtttgaaagtgacgtctggtcctatgggatttttctttgg
gagctattctctttaggaagcagcccttatcctggaatgccagtcgattctaagttctac
aagatgatcaaggaaggcttccggatgctcagccctgaacatgcacctgctgaaatgtat
gacataatgaagacttgctgggatgcggatcccctaaaaagaccaacattcaagcaaatt
gttcagctaattgagaagcagatttcagagagcaccaaccatatttactccaacttagca
aactgcagccccaaccgacagaagcctgtggtggaccattcagtgcggatcaattctgtc
ggcagcaccgcttcctcctcccaacctctgcttgtgcacgacgacgtctga

  All links  
Ontology (4)   
   KEGG BRITE (4)   
Pathway (11)   
   KEGG PATHWAY (11)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (4)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   OC (1)   
Protein sequence (4)   
   RefSeq(pep) (4)   
DNA sequence (4)   
   RefSeq(nuc) (4)   
Protein domain (8)   
   Pfam (8)   
All databases (37)   

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