KEGG   Rhinopithecus bieti (black snub-nosed monkey): 108544578
Entry
108544578         CDS       T04641                                 
Symbol
PKM
Name
(RefSeq) pyruvate kinase PKM isoform X1
  KO
K00873  pyruvate kinase [EC:2.7.1.40]
Organism
rbb  Rhinopithecus bieti (black snub-nosed monkey)
Pathway
rbb00010  Glycolysis / Gluconeogenesis
rbb00620  Pyruvate metabolism
rbb01100  Metabolic pathways
rbb01200  Carbon metabolism
rbb01230  Biosynthesis of amino acids
rbb04922  Glucagon signaling pathway
rbb04930  Type II diabetes mellitus
rbb05165  Human papillomavirus infection
rbb05203  Viral carcinogenesis
rbb05230  Central carbon metabolism in cancer
Module
rbb_M00001  Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate
rbb_M00002  Glycolysis, core module involving three-carbon compounds
Brite
KEGG Orthology (KO) [BR:rbb00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00010 Glycolysis / Gluconeogenesis
    108544578 (PKM)
   00620 Pyruvate metabolism
    108544578 (PKM)
 09150 Organismal Systems
  09152 Endocrine system
   04922 Glucagon signaling pathway
    108544578 (PKM)
 09160 Human Diseases
  09161 Cancer: overview
   05203 Viral carcinogenesis
    108544578 (PKM)
   05230 Central carbon metabolism in cancer
    108544578 (PKM)
  09172 Infectious disease: viral
   05165 Human papillomavirus infection
    108544578 (PKM)
  09167 Endocrine and metabolic disease
   04930 Type II diabetes mellitus
    108544578 (PKM)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:rbb04131]
    108544578 (PKM)
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:rbb04147]
    108544578 (PKM)
Enzymes [BR:rbb01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.1  Phosphotransferases with an alcohol group as acceptor
    2.7.1.40  pyruvate kinase
     108544578 (PKM)
Membrane trafficking [BR:rbb04131]
 Autophagy
  Chaperone mediated autophagy (CMA)
   Selective cargos
    108544578 (PKM)
Exosome [BR:rbb04147]
 Exosomal proteins
  Proteins found in most exosomes
   108544578 (PKM)
SSDB
Motif
Pfam: PK PK_C HpcH_HpaI
Other DBs
NCBI-GeneID: 108544578
NCBI-ProteinID: XP_017751282
UniProt: A0A2K6N015
Position
Unknown
AA seq 531 aa
MSKPHSEAGTAFIQTQQLHAAMADTFLEHMCRLDIDSPPITARNTGIICTIGPASRSVET
LKEMIKSGMNVARLNFSHGTHEYHAETIKNVRTATESFASDPILYRPVAVALDTKGPEIR
TGLIKGSGTAEVELKKGATLKITLDNAYMEKCDENILWLDYKNICKVVEVGSKIYVDDGL
ISLQVKQKGADFLVTEVENGGSLGSKKGVNLPGAAVDLPAVSEKDIQDLKFGVEQDVDMV
FASFIRKAADVHEVRKVLGEKGKNIKIISKIENHEGVRRFDEILEASDGIMVARGDLGIE
IPAEKVFLAQKMMIGRCNRAGKPVICATQMLESMIKKPRPTRAEGSDVANAVLDGADCIM
LSGETAKGDYPLEAVRMQHLIAREAEAAIYHLQLFEELRRLAPITSDPTEATAVGAVEAS
FKCCSGAIIVLTKSGRSAHQVARYRPRAPIIAVTRNPQTARQAHLYRGIFPVLCKDPVQE
AWAEDVDLRVNFAMNVGKARGFFKKGDVVIVLTGWRPGSGFTNTMRVVPVP
NT seq 1596 nt   +upstreamnt  +downstreamnt
atgtcgaagccccatagtgaagccgggactgccttcattcagacccagcagctgcatgca
gccatggctgacacattcctggagcacatgtgccgcctggacattgactcaccacccatc
acagcccggaacactggcatcatctgtaccattggcccagcttcccgatcagtggagacg
ttgaaggagatgattaagtctggaatgaatgtggctcgtctgaacttctctcatggaact
catgagtaccacgcagagaccatcaagaatgtgcgcacagccacagaaagctttgcttct
gaccccatcctctaccggcccgttgctgtggctctggacactaaaggacctgagatccga
actgggctcatcaaggggagcggcactgcagaggtggagctgaagaagggagccactctc
aaaatcacgctggataacgcctacatggaaaagtgtgacgagaacatcctatggctggac
tacaagaacatctgcaaggtggtagaagtgggcagcaagatctacgtggatgatgggctt
atttctcttcaggtgaagcagaaaggtgctgacttcctggtgacggaggtggaaaatggt
ggctccttgggcagcaagaagggtgtgaaccttcctggggctgctgtggacctgcctgct
gtgtcggaaaaggacatccaggatctgaagtttggggtcgagcaggatgtcgatatggtg
tttgcatcgttcatccgcaaggcagctgatgtccatgaagttaggaaggtcctgggagag
aagggaaagaacatcaagataatcagcaaaatcgagaatcatgaaggggttcggaggttt
gatgaaatcctggaggccagtgatgggatcatggtggctcgtggtgatctaggcattgag
attcctgcggagaaggtcttccttgctcagaagatgatgattgggcggtgcaaccgagct
gggaagcctgtcatctgtgctactcagatgctggagagcatgatcaagaagccccgcccc
acccgggctgaaggcagtgatgtggccaatgcagttttggatggagccgactgcatcatg
ctgtctggagaaacagccaaaggggactatcctctggaggctgtgcgcatgcagcacctg
attgcccgtgaggcagaggccgccatctaccacttgcaattatttgaggaactccgccgc
ctggcgcccattaccagcgaccccacagaagccaccgccgtgggtgccgtggaggcctcc
ttcaagtgctgcagtggggccataatcgtcctcaccaagtctggcaggtctgctcatcag
gtggccagataccgcccacgtgcccccatcattgctgtgacccggaatccccagacagct
cgtcaggcccacctgtaccgtggcatcttccctgtgctgtgcaaggacccagtccaggag
gcctgggctgaggacgtggacctccgggtgaactttgccatgaatgttggcaaggcccga
ggcttcttcaagaagggagatgtggtcattgtgctgactgggtggcgccctggctccggc
ttcaccaacaccatgcgtgttgttcctgtgccgtga

  All links  
Ontology (4)   
   KEGG BRITE (4)   
Pathway (12)   
   KEGG PATHWAY (10)   
   KEGG MODULE (2)   
Chemical substance (12)   
   KEGG COMPOUND (12)   
Chemical reaction (6)   
   KEGG ENZYME (1)   
   KEGG REACTION (5)   
Genome (1)   
   KEGG GENOME (1)   
Gene (4)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   OC (1)   
Protein sequence (7)   
   UniProt (1)   
   RefSeq(pep) (6)   
DNA sequence (6)   
   RefSeq(nuc) (6)   
Protein domain (3)   
   Pfam (3)   
All databases (55)   

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