KEGG   Rickettsiales bacterium Ac37b: NOVO_01075
Entry
NOVO_01075        CDS       T03234                                 
Symbol
topA
Name
(GenBank) DNA topoisomerase 1
  KO
K03168  DNA topoisomerase I [EC:5.6.2.1]
Organism
rbt  Rickettsiales bacterium Ac37b
Brite
KEGG Orthology (KO) [BR:rbt00001]
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03032 DNA replication proteins [BR:rbt03032]
    NOVO_01075 (topA)
   03400 DNA repair and recombination proteins [BR:rbt03400]
    NOVO_01075 (topA)
Enzymes [BR:rbt01000]
 5. Isomerases
  5.6  Isomerases altering macromolecular conformation
   5.6.2  Enzymes altering nucleic acid conformation
    5.6.2.1  DNA topoisomerase
     NOVO_01075 (topA)
DNA replication proteins [BR:rbt03032]
 Prokaryotic type
  DNA Topoisomerases
   NOVO_01075 (topA)
DNA repair and recombination proteins [BR:rbt03400]
 Prokaryotic type
  DSBR (double strand breaks repair)
   NHEJ (non-homologous end-joining)
    SHIIR (short-homology-independent illegitimate recombination)
     Facilitator
      NOVO_01075 (topA)
SSDB
Motif
Pfam: Topoisom_bac Toprim_C_rpt Toprim zf-C4_Topoisom Toprim_4 Plasmod_MYXSPDY
Other DBs
NCBI-ProteinID: AIL64620
UniProt: A0A077FJB6
Position
215440..218001
AA seq 853 aa
MKLVIVESPAKAKTINKYLGKDYQVVASYGHIRDLPSKNGSVIPEENFTMIYEVNDKSRK
HIKPIIDASKKAEQIFLATDPDREGESISWHIVEALKDLKAIKKNIPVKRVVFNEITKKA
VLEAMQHPRDIDMDLVNAQQARRALDYLVGFTLSPVLWRKLPGSRSAGRVQSVALRLICD
REVEIETFITREYWDIKVNLLNKQDELFTSTLTHLNGEKLDKFALSSEKEAQKIVQFLQK
KLYHVDNIEEKQVKRNPLPPFITSSLQQEASRKLGFSPDYTMRLAQKLYEGVSIEGETVG
LITYMRTDGVQLAQEATNSIRQLINKSFGKEYLPSSPRIYKSKVKNAQEAHEAIRPTNVN
LDPLQAKKYLDKNSFELYELIWKRTVACQMESAILNVLSVIIKTDDNETILKATGSTLKF
DGFYRLYREILDSDSNNNEEEENKILPKLDIGDKLKLSEVLPRQHFTEPPPRFSEASLIK
KLEELGIGRPSTYAPTISLLQDRNYIHLDKKRFIPDERGRLVTTFLISFFQRYVEYDFTA
KLENELDHISAGDLEWKLFLKNFWYDFEANVTEVKQYDIGQILEKISILLEPYLFPNSDK
NKECPSCTNGTLALKLGKFGAFIACSNYPECKYTRKIGDSDEQDTPIVADINKLGIDEDT
GLDITLRQGPYGYYIQLGEADEENKKPKRISLPKSIDPQELSLEQAKALLNLPREVGIHP
ETGQVVKAGIGRFGPYLFYNKSYTSIPASDDILTIGINRAVSLIAEKGSKKIEPVKVLGM
HPVLNQELAVYEGRYGLYIKLGKVNISLPKNINLDELTLQETVDIVDTYQEKHPEKKISS
KKTTTTKKKKAKS
NT seq 2562 nt   +upstreamnt  +downstreamnt
atgaaattggtaatagtagaatcccctgctaaggctaaaactattaataaatatttaggt
aaagattatcaagtggtagcttcttatggtcatattcgggatttaccttcaaagaatggt
tctgtgataccagaagaaaattttactatgatttatgaagttaatgataaatctagaaaa
catataaagcctataatagatgcttctaagaaagcagaacaaatttttttagcaacagat
cctgatcgtgaaggagaatctatatcatggcatatcgttgaagctttaaaagatctcaaa
gctattaaaaaaaatattccagtaaaaagagtagtatttaatgagattactaaaaaagca
gtattagaggcaatgcaacatccgcgtgatatcgatatggatttggttaatgctcaacaa
gctagaagggccctggattaccttgttggatttacgttatctccagtattatggagaaaa
ttaccgggtagtcgttcagcagggagagtgcaatccgtagcacttcgattaatttgtgat
cgcgaagtagaaatagaaacttttattaccagagaatattgggatataaaagttaattta
ttaaacaaacaagatgagctctttacgtcaacacttactcatttgaatggagaaaagcta
gataaatttgcactctcaagtgagaaggaggcacaaaaaatagtacaattcttacagaag
aaattatatcatgttgataatattgaagaaaagcaagttaagagaaatcctcttcctcca
tttattacatcatctttgcaacaagaggcatcaagaaagctagggtttagccctgattac
acgatgcgtcttgctcaaaagctttacgaaggagtaagtattgaaggagaaactgttgga
ctcattacctatatgagaacagatggggtacagcttgctcaagaagcaacgaatagtatt
agacagttgattaataagagttttgggaaagagtatcttccttcatcacctcgtatttat
aagagcaaagtaaaaaatgctcaagaagcacatgaagccattaggccgaccaatgttaat
ttagatccgctgcaagctaaaaaatatttagataaaaattcgtttgaactttatgaactg
atttggaaacgtacagtagcttgtcagatggaaagtgctattttaaatgtgttatctgta
attattaaaactgatgacaatgagacaattttaaaagctacaggatctacgttaaaattt
gatggattttatcgtctatatcgtgaaatattggatagtgattcgaataataatgaagaa
gaggaaaataaaatattacctaaattagatataggtgataaattaaaattatcggaagta
ttaccgaggcaacattttactgaacctccaccgcgctttagtgaagcaagtttgataaaa
aaattagaagaattgggtataggtcgtccttccacttatgctcctacaatttccttgtta
caagatcgtaattatatacacttagataaaaagagatttatacctgatgaacgaggaaga
ctagttactacatttttaataagtttctttcagagatatgtggagtatgattttactgct
aaattagaaaatgaactagatcatatatcagcaggtgacttagagtggaaattatttttg
aaaaatttctggtatgactttgaagcgaatgttacagaagtaaagcaatatgacattggg
caaatattagagaaaatttctattttgttagaaccgtatttatttccaaatagtgataag
aataaagaatgtccttcatgtacaaatggtactcttgctttaaaactaggtaaatttgga
gcatttattgcctgttcaaattatcctgagtgtaaatatactcgaaaaataggtgatagt
gatgaacaggatacgcctatagttgctgatattaataaattaggaatagatgaagatacc
ggtttagatataactttacgtcaagggccatatgggtattatatacaactaggggaagct
gacgaggaaaataaaaaacctaaacgtatttctttacctaagtctattgatccgcaagaa
ttgagtttagaacaggcaaaagccttattaaatttgccaagagaagtgggaatacatcca
gaaactggacaggttgttaaagctggtataggtagatttggaccttatcttttttataat
aaatcgtatactagcatacctgctagtgatgatatattaacaataggtattaatcgagca
gtatctttaattgcagaaaaaggttcaaaaaagattgaacctgtaaaagttttaggaatg
catcctgtactaaatcaagagttagcagtatatgagggaagatatgggttatatataaaa
ttaggtaaagtgaacatatcattacctaaaaatataaatttggatgaattaactttgcaa
gaaacagttgatatcgtggatacatatcaagaaaaacatcctgaaaagaaaatatcttct
aaaaaaactactactaccaaaaagaaaaaagctaagtcataa

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Ontology (4)   
   KEGG BRITE (4)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (81)   
   KEGG ORTHOLOGY (1)   
   RefGene (78)   
   NCBI-PROTEINID (1)   
   OC (1)   
Protein sequence (1)   
   UniProt (1)   
Protein domain (6)   
   Pfam (6)   
All databases (94)   

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