KEGG   REACTION: R01493
Entry
R01493                      Reaction                               
Name
N-acylsphingosine amidohydrolase
Definition
N-Acylsphingosine + H2O <=> Carboxylate + Sphingosine
Equation
C00195 + C00001 <=> C00060 + C00319
Reaction class
RC00064  C00195_C00319
RC00328  C00060_C00195
Enzyme
3.5.1.23
Brite
Enzymatic reactions [BR:br08201]
 3. Hydrolase reactions
  3.5  Acting on carbon-nitrogen bonds, other than peptide bonds
   3.5.1  In linear amides
    3.5.1.23
     R01493  N-Acylsphingosine + H2O <=> Carboxylate + Sphingosine
IUBMB reaction hierarchy [BR:br08202]
 3. Hydrolase reactions
  3.5.1.23
   R01493  Carboxylate
Other DBs
RHEA: 20859

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Ontology (2)   
   KEGG BRITE (2)   
Chemical substance (4)   
   KEGG COMPOUND (4)   
Chemical reaction (3)   
   KEGG ENZYME (1)   
   KEGG RCLASS (2)   
All databases (9)   

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KEGG   REACTION: R01494
Entry
R01494                      Reaction                               
Name
N-acylsphingosine amidohydrolase
Definition
N-Acylsphingosine + H2O <=> Fatty acid + Sphingosine
Equation
C00195 + C00001 <=> C00162 + C00319
Reaction class
RC00064  C00195_C00319
RC00328  C00162_C00195
Enzyme
3.5.1.23
Pathway
rn00600  Sphingolipid metabolism
rn01100  Metabolic pathways
Module
M00099  Sphingosine biosynthesis
Brite
Enzymatic reactions [BR:br08201]
 3. Hydrolase reactions
  3.5  Acting on carbon-nitrogen bonds, other than peptide bonds
   3.5.1  In linear amides
    3.5.1.23
     R01494  N-Acylsphingosine + H2O <=> Fatty acid + Sphingosine
IUBMB reaction hierarchy [BR:br08202]
 3. Hydrolase reactions
  3.5.1.23
   R01493  Carboxylate
    R01494  Fatty acid
Orthology
K01441  alkaline ceramidase [EC:3.5.1.23]
K12348  acid ceramidase [EC:3.5.1.23]
K12349  neutral ceramidase [EC:3.5.1.23]

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (5)   
   KEGG PATHWAY (4)   
   KEGG MODULE (1)   
Chemical substance (4)   
   KEGG COMPOUND (4)   
Chemical reaction (4)   
   KEGG ENZYME (1)   
   KEGG RCLASS (2)   
   SABIO-RK (1)   
Gene (3180)   
   KEGG ORTHOLOGY (3)   
   KEGG GENES (3177)   
All databases (3195)   

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KEGG   REACTION: R06518
Entry
R06518                      Reaction                               
Name
N-acylsphingosine amidohydrolase
Definition
Dihydroceramide + H2O <=> Fatty acid + Sphinganine
Equation
C12126 + C00001 <=> C00162 + C00836
Reaction class
RC00064  C00836_C12126
RC00328  C00162_C12126
Enzyme
3.5.1.23
Pathway
rn00600  Sphingolipid metabolism
rn01100  Metabolic pathways
Brite
Enzymatic reactions [BR:br08201]
 3. Hydrolase reactions
  3.5  Acting on carbon-nitrogen bonds, other than peptide bonds
   3.5.1  In linear amides
    3.5.1.23
     R06518  Dihydroceramide + H2O <=> Fatty acid + Sphinganine
Orthology
K04711  dihydroceramidase [EC:3.5.1.-]
K12348  acid ceramidase [EC:3.5.1.23]
K12349  neutral ceramidase [EC:3.5.1.23]

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Ontology (1)   
   KEGG BRITE (1)   
Pathway (4)   
   KEGG PATHWAY (4)   
Chemical substance (4)   
   KEGG COMPOUND (4)   
Chemical reaction (3)   
   KEGG ENZYME (1)   
   KEGG RCLASS (2)   
Gene (3283)   
   KEGG ORTHOLOGY (3)   
   KEGG GENES (3280)   
All databases (3295)   

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KEGG   REACTION: R06528
Entry
R06528                      Reaction                               
Name
phytoceramide amidohydrolase
Definition
Phytoceramide + H2O <=> Fatty acid + Phytosphingosine
Equation
C12145 + C00001 <=> C00162 + C12144
Comment
YPC1, YDC1
Reaction class
RC00064  C12144_C12145
RC00328  C00162_C12145
Enzyme
3.5.1.23
Pathway
rn00600  Sphingolipid metabolism
rn01100  Metabolic pathways
Brite
Enzymatic reactions [BR:br08201]
 3. Hydrolase reactions
  3.5  Acting on carbon-nitrogen bonds, other than peptide bonds
   3.5.1  In linear amides
    3.5.1.23
     R06528  Phytoceramide + H2O <=> Fatty acid + Phytosphingosine
Orthology
K05848  phytoceramidase [EC:3.5.1.-]
K12348  acid ceramidase [EC:3.5.1.23]
K12349  neutral ceramidase [EC:3.5.1.23]

  All links  
Ontology (1)   
   KEGG BRITE (1)   
Pathway (4)   
   KEGG PATHWAY (4)   
Chemical substance (4)   
   KEGG COMPOUND (4)   
Chemical reaction (3)   
   KEGG ENZYME (1)   
   KEGG RCLASS (2)   
Gene (2173)   
   KEGG ORTHOLOGY (3)   
   KEGG GENES (2170)   
All databases (2185)   

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