KEGG   REACTION: R02107
Entry
R02107                      Reaction                               
Name
xanthine:oxygen oxidoreductase
Definition
Xanthine + H2O + Oxygen <=> Urate + Hydrogen peroxide
Equation
C00385 + C00001 + C00007 <=> C00366 + C00027
Reaction class
RC00143  C00366_C00385
RC02755  C00007_C00027
Enzyme
1.17.3.2
Pathway
rn00230  Purine metabolism
rn01100  Metabolic pathways
Module
M00546  Purine degradation, xanthine => urea
M00958  Adenine ribonucleotide degradation, AMP => Urate
M00959  Guanine ribonucleotide degradation, GMP => Urate
Brite
Enzymatic reactions [BR:br08201]
 1. Oxidoreductase reactions
  1.17  Acting on CH or CH2 groups
   1.17.3  With oxygen as acceptor
    1.17.3.2
     R02107  Xanthine + H2O + Oxygen <=> Urate + Hydrogen peroxide
Orthology
K00106  xanthine dehydrogenase/oxidase [EC:1.17.1.4 1.17.3.2]
Other DBs
RHEA: 21135

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Ontology (1)   
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Pathway (7)   
   KEGG PATHWAY (4)   
   KEGG MODULE (3)   
Chemical substance (5)   
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Chemical reaction (4)   
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Gene (2142)   
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KEGG   REACTION: R00069
Entry
R00069                      Reaction                               
Name
4-imidazolone-5-propanoate:oxygen oxidoreductase
Definition
Hydantoin-5-propionate + Hydrogen peroxide <=> 4-Imidazolone-5-propanoate + Oxygen + H2O
Equation
C05565 + C00027 <=> C03680 + C00007 + C00001
Reaction class
RC00969  C03680_C05565
RC02755  C00007_C00027
Enzyme
1.14.13.-       1.17.3.2
Pathway
rn00340  Histidine metabolism
Brite
Enzymatic reactions [BR:br08201]
 1. Oxidoreductase reactions
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.13  With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.13.-
     R00069  Hydantoin-5-propionate + Hydrogen peroxide <=> 4-Imidazolone-5-propanoate + Oxygen + H2O
  1.17  Acting on CH or CH2 groups
   1.17.3  With oxygen as acceptor
    1.17.3.2
     R00069  Hydantoin-5-propionate + Hydrogen peroxide <=> 4-Imidazolone-5-propanoate + Oxygen + H2O

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Ontology (1)   
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Pathway (2)   
   KEGG PATHWAY (2)   
Chemical substance (5)   
   KEGG COMPOUND (5)   
Chemical reaction (3)   
   KEGG ENZYME (1)   
   KEGG RCLASS (2)   
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KEGG   REACTION: R01769
Entry
R01769                      Reaction                               
Name
hypoxanthine:oxygen oxidoreductase
Definition
Hypoxanthine + Oxygen + H2O <=> Xanthine + Hydrogen peroxide
Equation
C00262 + C00007 + C00001 <=> C00385 + C00027
Reaction class
RC00143  C00262_C00385
RC02755  C00007_C00027
Enzyme
1.17.3.2
Pathway
rn00230  Purine metabolism
rn01100  Metabolic pathways
rn01232  Nucleotide metabolism
Module
M00958  Adenine ribonucleotide degradation, AMP => Urate
Brite
Enzymatic reactions [BR:br08201]
 1. Oxidoreductase reactions
  1.17  Acting on CH or CH2 groups
   1.17.3  With oxygen as acceptor
    1.17.3.2
     R01769  Hypoxanthine + Oxygen + H2O <=> Xanthine + Hydrogen peroxide
Orthology
K00106  xanthine dehydrogenase/oxidase [EC:1.17.1.4 1.17.3.2]
Other DBs
RHEA: 68015

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Pathway (7)   
   KEGG PATHWAY (6)   
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Chemical substance (5)   
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Chemical reaction (3)   
   KEGG ENZYME (1)   
   KEGG RCLASS (2)   
Gene (2142)   
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   KEGG GENES (2141)   
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KEGG   REACTION: R07942
Entry
R07942                      Reaction                               
Name
1-methylxanthine:oxygen oxidoreductase
Definition
1-Methylxanthine + H2O + Oxygen <=> 1-Methyluric acid + Hydrogen peroxide
Equation
C16358 + C00001 + C00007 <=> C16359 + C00027
Reaction class
RC00143  C16358_C16359
RC02755  C00007_C00027
Enzyme
1.17.3.2
Pathway
rn00232  Caffeine metabolism
Brite
Enzymatic reactions [BR:br08201]
 1. Oxidoreductase reactions
  1.17  Acting on CH or CH2 groups
   1.17.3  With oxygen as acceptor
    1.17.3.2
     R07942  1-Methylxanthine + H2O + Oxygen <=> 1-Methyluric acid + Hydrogen peroxide
Orthology
K00106  xanthine dehydrogenase/oxidase [EC:1.17.1.4 1.17.3.2]

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Pathway (2)   
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Chemical substance (5)   
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Chemical reaction (3)   
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Gene (2142)   
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KEGG   REACTION: R07977
Entry
R07977                      Reaction                               
Name
1,7-dimethylxanthine:oxygen oxidoreductase
Definition
1,7-Dimethylxanthine + Oxygen + H2O <=> 1,7-Dimethyluric acid + Hydrogen peroxide
Equation
C13747 + C00007 + C00001 <=> C16356 + C00027
Reaction class
RC02017  C13747_C16356
RC02755  C00007_C00027
Enzyme
1.17.3.2
Pathway
rn00232  Caffeine metabolism
rn01100  Metabolic pathways
rn01110  Biosynthesis of secondary metabolites
Brite
Enzymatic reactions [BR:br08201]
 1. Oxidoreductase reactions
  1.17  Acting on CH or CH2 groups
   1.17.3  With oxygen as acceptor
    1.17.3.2
     R07977  1,7-Dimethylxanthine + Oxygen + H2O <=> 1,7-Dimethyluric acid + Hydrogen peroxide
Orthology
K00106  xanthine dehydrogenase/oxidase [EC:1.17.1.4 1.17.3.2]

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Pathway (6)   
   KEGG PATHWAY (6)   
Chemical substance (5)   
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Chemical reaction (4)   
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Gene (2142)   
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KEGG   REACTION: R07978
Entry
R07978                      Reaction                               
Name
3,7-dimethylxanthine:oxygen oxidoreductase
Definition
Theobromine + H2O + Oxygen <=> 3,7-Dimethyluric acid + Hydrogen peroxide
Equation
C07480 + C00001 + C00007 <=> C16360 + C00027
Reaction class
RC02017  C07480_C16360
RC02755  C00007_C00027
Enzyme
1.17.3.2
Pathway
rn00232  Caffeine metabolism
Brite
Enzymatic reactions [BR:br08201]
 1. Oxidoreductase reactions
  1.17  Acting on CH or CH2 groups
   1.17.3  With oxygen as acceptor
    1.17.3.2
     R07978  Theobromine + H2O + Oxygen <=> 3,7-Dimethyluric acid + Hydrogen peroxide
Orthology
K00106  xanthine dehydrogenase/oxidase [EC:1.17.1.4 1.17.3.2]

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Ontology (1)   
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Pathway (2)   
   KEGG PATHWAY (2)   
Chemical substance (5)   
   KEGG COMPOUND (5)   
Chemical reaction (4)   
   KEGG ENZYME (1)   
   KEGG RCLASS (2)   
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Gene (2142)   
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KEGG   REACTION: R07979
Entry
R07979                      Reaction                               
Name
7-methylxanthine:oxygen oxidoreductase
Definition
7-Methylxanthine + Oxygen + H2O <=> 7-Methyluric acid + Hydrogen peroxide
Equation
C16353 + C00007 + C00001 <=> C16355 + C00027
Reaction class
RC02017  C16353_C16355
RC02755  C00007_C00027
Enzyme
1.17.3.2
Pathway
rn00232  Caffeine metabolism
Brite
Enzymatic reactions [BR:br08201]
 1. Oxidoreductase reactions
  1.17  Acting on CH or CH2 groups
   1.17.3  With oxygen as acceptor
    1.17.3.2
     R07979  7-Methylxanthine + Oxygen + H2O <=> 7-Methyluric acid + Hydrogen peroxide
Orthology
K00106  xanthine dehydrogenase/oxidase [EC:1.17.1.4 1.17.3.2]

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Ontology (1)   
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Pathway (2)   
   KEGG PATHWAY (2)   
Chemical substance (5)   
   KEGG COMPOUND (5)   
Chemical reaction (4)   
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Gene (2142)   
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KEGG   REACTION: R08235
Entry
R08235                      Reaction                               
Name
6-mercaptopurin:oxygen oxidoreductase
Definition
6-Mercaptopurine + 2 H2O + 2 Oxygen <=> 6-Thiourate + 2 Hydrogen peroxide
Equation
C02380 + 2 C00001 + 2 C00007 <=> C16613 + 2 C00027
Comment
two-step reaction
Reaction class
RC02199  C02380_C16613
RC02755  C00007_C00027
Enzyme
1.17.3.2
Pathway
rn00983  Drug metabolism - other enzymes
Brite
Enzymatic reactions [BR:br08201]
 1. Oxidoreductase reactions
  1.17  Acting on CH or CH2 groups
   1.17.3  With oxygen as acceptor
    1.17.3.2
     R08235  6-Mercaptopurine + 2 H2O + 2 Oxygen <=> 6-Thiourate + 2 Hydrogen peroxide
Orthology
K00106  xanthine dehydrogenase/oxidase [EC:1.17.1.4 1.17.3.2]

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Ontology (1)   
   KEGG BRITE (1)   
Pathway (2)   
   KEGG PATHWAY (2)   
Chemical substance (5)   
   KEGG COMPOUND (5)   
Chemical reaction (3)   
   KEGG ENZYME (1)   
   KEGG RCLASS (2)   
Gene (2142)   
   KEGG ORTHOLOGY (1)   
   KEGG GENES (2141)   
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