KEGG   REACTION: R02570Help
Entry
R02570                      Reaction                               

Name
succinyl-CoA:enzyme N6-(dihydrolipoyl)lysine S-succinyltransferase
Definition
Succinyl-CoA + Enzyme N6-(dihydrolipoyl)lysine <=> CoA + [Dihydrolipoyllysine-residue succinyltransferase] S-succinyldihydrolipoyllysine
Equation
Comment
2-oxoglutarate dehydrogenase complex:dihydrolipoyllysine-residue succinyltransferase
a part of multi-step reaction (see R08549, R01700+R02570+R07618)
following after R01700
Reaction class
RC00004  C00010_C00091  C15973_C16254
RC02727  C00091_C16254
Enzyme
Pathway
rn00020  Citrate cycle (TCA cycle)
Module
M00009  Citrate cycle (TCA cycle, Krebs cycle)
M00011  Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate
Orthology
K00658  2-oxoglutarate dehydrogenase E2 component (dihydrolipoamide succinyltransferase) [EC:2.3.1.61]
Other DBs
RHEA: 15216

KEGG   REACTION: R01933Help
Entry
R01933                      Reaction                               

Name
2-oxoadipate dehydrogenase complex
Definition
2-Oxoadipate + CoA + NAD+ <=> Glutaryl-CoA + CO2 + NADH + H+
Equation
Comment
2-oxoglutarate dehydrogenase complex (see R08549)
multi-step reaction (see R01940+R02571+R07618)
Reaction class
RC00001  C00003_C00004
RC00004  C00010_C00527
RC02833  C00322_C00527
Enzyme
1.2.4.2         1.8.1.4         2.3.1.61
Pathway
rn00310  Lysine degradation
rn00380  Tryptophan metabolism
rn01100  Metabolic pathways
rn01130  Biosynthesis of antibiotics
Module
M00032  Lysine degradation, lysine => saccharopine => acetoacetyl-CoA
Orthology
K00382  dihydrolipoamide dehydrogenase [EC:1.8.1.4]
K00658  2-oxoglutarate dehydrogenase E2 component (dihydrolipoamide succinyltransferase) [EC:2.3.1.61]
K15791  probable 2-oxoglutarate dehydrogenase E1 component DHKTD1 [EC:1.2.4.2]
Other DBs
RHEA: 30798

KEGG   REACTION: R02571Help
Entry
R02571                      Reaction                               

Name
Glutaryl-CoA:dihydrolipoamide S-succinyltransferase
Definition
Glutaryl-CoA + Enzyme N6-(dihydrolipoyl)lysine <=> CoA + [Dihydrolipoyllysine-residue succinyltransferase] S-glutaryldihydrolipoyllysine
Equation
Comment
2-oxoglutarate dehydrogenase complex:dihydrolipoyllysine-residue succinyltransferase
a part of multi-step reaction (see R01933, R01940+R02571+R07618)
following after R01940
Reaction class
RC00004  C00010_C00527  C06157_C15973
RC02727  C00527_C06157
Enzyme
Orthology
K00658  2-oxoglutarate dehydrogenase E2 component (dihydrolipoamide succinyltransferase) [EC:2.3.1.61]

KEGG   REACTION: R08549Help
Entry
R08549                      Reaction                               

Name
2-Oxoglutarate dehydrogenase complex
Definition
2-Oxoglutarate + CoA + NAD+ <=> Succinyl-CoA + CO2 + NADH + H+
Equation
Comment
multi-step reaction (see R01700+R02570+R07618)
Reaction class
RC00001  C00003_C00004
RC00004  C00010_C00091
RC02833  C00026_C00091
Enzyme
1.2.4.2         1.8.1.4         2.3.1.61
Pathway
rn01100  Metabolic pathways
rn01110  Biosynthesis of secondary metabolites
rn01120  Microbial metabolism in diverse environments
rn01130  Biosynthesis of antibiotics
rn01200  Carbon metabolism
Orthology
K00164  2-oxoglutarate dehydrogenase E1 component [EC:1.2.4.2]
K00382  dihydrolipoamide dehydrogenase [EC:1.8.1.4]
K00658  2-oxoglutarate dehydrogenase E2 component (dihydrolipoamide succinyltransferase) [EC:2.3.1.61]
Other DBs
RHEA: 27789

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