KEGG   REACTION: R08901Help
Entry
R08901                      Reaction                               

Name
2'''-acetyl-6'''-hydroxyneomycin-C hydrolase (acetate-forming)
Definition
2'''-N-Acetyl-6'''-deamino-6'''-hydroxyneomycin C + H2O <=> 6'''-Deamino-6'''-hydroxyneomycin C + Acetate
Equation
Reaction class
RC00166  C17587_C17588
RC00300  C00033_C17587
Enzyme
Pathway
rn00524  Neomycin, kanamycin and gentamicin biosynthesis
rn01130  Biosynthesis of antibiotics
Orthology
K17078  2'-N-acetylparomamine deacetylase / 2'''-acetyl-6'''-hydroxyneomycin deacetylase [EC:3.5.1.112 3.5.1.113]
Reference
1  [PMID:17226887]
  Authors
Truman AW, Huang F, Llewellyn NM, Spencer JB.
  Title
Characterization of the enzyme BtrD from Bacillus circulans and revision of its functional assignment in the biosynthesis of butirosin.
  Journal
Angew Chem Int Ed Engl 46:1462-4 (2007)
DOI:10.1002/anie.200604194
Other DBs
RHEA: 34054

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