LOCUS NC_001402 2630 bp ss-RNA linear VRL 13-AUG-2018
DEFINITION Avian carcinoma virus, complete genome.
ACCESSION NC_001402
VERSION NC_001402.1
DBLINK BioProject: PRJNA485481
KEYWORDS RefSeq.
SOURCE Avian carcinoma virus
ORGANISM Avian carcinoma virus
Viruses; Riboviria; Pararnavirae; Artverviricota; Revtraviricetes;
Ortervirales; Retroviridae; Orthoretrovirinae; Alpharetrovirus.
REFERENCE 1 (bases 1 to 2630)
AUTHORS Patschinsky,T., Jansen,H.W., Blocker,H., Frank,R. and Bister,K.
TITLE Structure and transforming function of transduced mutant alleles of
the chicken c-myc gene
JOURNAL J. Virol. 59 (2), 341-353 (1986)
PUBMED 3016301
REFERENCE 2 (bases 1 to 2630)
CONSRTM NCBI Genome Project
TITLE Direct Submission
JOURNAL Submitted (01-AUG-2000) National Center for Biotechnology
Information, NIH, Bethesda, MD 20894, USA
COMMENT PROVISIONAL REFSEQ: This record has not yet been subject to final
NCBI review. The reference sequence was derived from M14008.
Computer-readable sequence kindly provided by K.Bister
(26-JAN-1987).
The sequence presented below represents the complete proviral
genome including two complete LTRs derived from figure 3 in [1].
The terminal inverted repeats 5' 'aatg' and 'catt' 3' (positions
1-4 and 2627-2630 respectively) may not be completely present in
the integrated proviral DNA.
The MH2E21 myc protein differs from chicken c-myc and MH2 virus
v-myc. [1] constucted various mutants of MH2E21 that expressed
variant myc proteins.
[1] describes the construction and isolation of the MH2E21
retrovirus. The MH2E21 virus appears to be a recombinant between
ring-necked pheasant virus and a deletion mutant of MH2 that was
constructed in vitro.
The MH2E21 virus lacks gag, pol and env genes, and thus needs a
helper virus to reproduce.
COMPLETENESS: full length.
FEATURES Location/Qualifiers
source 1..2630
/organism="Avian carcinoma virus"
/mol_type="genomic RNA"
/strain="MH2E21"
/db_xref="taxon:11958"
repeat_region 1..357
/note="5' LTR"
/rpt_type=long_terminal_repeat
repeat_region 257..277
/note="5' R region"
gene 655..1926
/locus_tag="ACVgp1"
/db_xref="GeneID:1491953"
CDS 655..1926
/locus_tag="ACVgp1"
/codon_start=1
/product="v-myc (59/61 kDa) protein"
/protein_id="NP_040504.1"
/db_xref="GeneID:1491953"
/translation="MEAVIKAAAAAMPLSVSLPSKNYDYDYDSVQPYFYFEEEEENFY
LAAQQRSSELQPPAPSEDIWKKFELLPAPPLSPSCRSNLAAASCFPSTADQLEMVTEL
LGGDMVNQSSICDPDDESFVKSIIIRDCMWSGFSAAAKLEKVVSEKLATYKASRREGG
PAAASRPGPPPSGPPPPPAGPAASAGLYLHDLGAAAAGCIGSSVVFPCPLGRRGPPGA
GPAALLGVDAPPTAGGGSEEEQEEDEEIDVVTLAEANESESSTESSTEASEEHCKPHH
SPLVLERCHVNIHQHNYAAPPSTKVEYPAAKRLKLDSGRVLKQVSNNRKCSSPRTSDS
EVNDKRRTHNVLERQRRNELKLSFFALRDQIPEVANNEKAPKVVILKRATEYVLSIQS
DEHRLIAEKEQLRRRREQLKHKLEQLRNSRA"
misc_feature 691..1641
/locus_tag="ACVgp1"
/note="Myc amino-terminal region; Region: Myc_N;
pfam01056"
/db_xref="CDD:426019"
misc_feature 1657..1908
/locus_tag="ACVgp1"
/note="basic Helix-Loop-Helix-zipper (bHLHzip) domain
found in c-Myc and similar proteins; Region:
bHLHzip_c-Myc; cd11458"
/db_xref="CDD:381464"
misc_feature order(1657..1659,1669..1674,1681..1686,1690..1698,
1702..1707,1717..1719,1777..1782)
/locus_tag="ACVgp1"
/note="DNA binding site [nucleotide binding]"
/db_xref="CDD:381464"
misc_feature order(1714..1716,1723..1728,1732..1737,1744..1746,
1783..1785,1792..1797,1804..1806,1810..1818,1822..1827,
1831..1836,1843..1845,1852..1857,1864..1869,1873..1881,
1885..1890,1894..1908)
/locus_tag="ACVgp1"
/note="tetramer interface [polypeptide binding]; other
site"
/db_xref="CDD:381464"
misc_feature order(1714..1716,1723..1728,1732..1737,1744..1746,
1783..1785,1792..1797,1804..1806,1810..1818,1822..1827,
1831..1836,1843..1845,1852..1857,1864..1869,1873..1878,
1885..1887,1894..1899,1906..1908)
/locus_tag="ACVgp1"
/note="dimer interface [polypeptide binding]; other site"
/db_xref="CDD:381464"
repeat_region 2274..2630
/note="3' LTR"
/rpt_type=long_terminal_repeat
repeat_region 2530..2550
/note="3' R region"
ORIGIN
1 aatgtagtct tatgcaatac tcttgtagtc ttgcaacatg cttatgtaac gatgagttag
61 caacatgcct tataaggaaa gaaaaagcac cgtgcatgcc gattggtgga agtaaggtgg
121 tatgatcgtg gtatgatcgt ggtatgatcg tgccttatta ggaaggcaac agacgggtct
181 aacacggatt ggacgaacca ctgaattccg cattgcagag atattgtatt taagtgccta
241 gctcgataca ataaacgcca tttgaccatt caccacattg gtgtgcacct gggttgatgg
301 ccggaccgtt gattccctga cgactacgag cacatgcatg aagcagaagg cttcatttgg
361 tgaccccgac gtgatcgtta gggaatagtg gtcggccaca ggcggcgtgg cgatcctgtc
421 ctcatccgtc tcgcttattc ggggagcgga cgatgaccct agtagagggg gctgcggctt
481 aggagggcag aagctgagtg acgtcggagg gagctccacg gccgggggcc aagataccct
541 accgagaact cagagagtcg ttggaagacg ggaagaaagc ccgacgactg agcggtccac
601 cccaggcgtg attccggttg ctctgcgtga ttccggtcgc ccggtgaatc aagcatggaa
661 gccgtcataa aggcagcagc cgccgcgatg ccgctcagcg tcagcctccc cagcaagaac
721 tacgattacg actacgactc ggtgcagccc tacttctact tcgaggagga ggaggagaac
781 ttctacctgg cggcgcagca gcggagcagc gagctgcagc ctccagcccc gtccgaggac
841 atctggaaga agtttgagct cctgcccgcg ccgcccctct cgcccagctg ccgctccaac
901 ctggccgccg cctcctgctt cccttccacc gccgaccagc tggagatggt gacggagctg
961 ctcggggggg acatggtcaa ccagagctcc atctgcgacc cggacgacga atccttcgtc
1021 aaatccatca tcatccggga ctgcatgtgg agcggcttct ccgccgccgc caagctggag
1081 aaggtggtgt cggagaagct cgccacctac aaagcctccc gccgggaggg gggccccgcc
1141 gccgcctccc gacccggccc gccgccctcg gggccgccgc ctcctcccgc cggccccgcc
1201 gcctcggccg gcctctacct gcacgacctg ggagccgcgg ccgccggctg catcggctcc
1261 tcggtggtct tcccctgccc gctcggcagg cgcggcccgc ccggcgccgg ccccgcggct
1321 ctgctggggg tcgacgcgcc gcccacggcc ggcggcggct cggaggaaga acaagaagaa
1381 gatgaggaaa tcgatgtcgt tacattagct gaagcgaacg agtctgaatc cagcacagag
1441 tccagcacag aagcatcaga ggagcactgt aagccccacc acagtccgct ggtcctcgag
1501 cggtgtcacg tcaacatcca ccaacacaac tacgctgctc ctccctccac caaggtggaa
1561 tacccagccg ccaagaggct aaagttggac agtggcaggg tcctcaaaca ggtcagcaac
1621 aaccgaaaat gctccagtcc ccgcacgtca gactcagagg tgaacgacaa gaggcgaacg
1681 cacaacgtct tggagcgcca gcgaaggaat gagctgaagc tgagcttctt tgccctgcgg
1741 gaccagatac ccgaggtggc caacaacgag aaggcgccca aggttgtcat cctgaaaaga
1801 gccacggagt acgttctgtc tatccaatcg gacgagcaca gactgatcgc agagaaagag
1861 cagttgaggc ggaggagaga acagttgaaa cacaaacttg agcagctaag gaactctcgt
1921 gcataggaac tcttggacat cacttagaat accccaaact agactccgtg tgatagctgg
1981 ttggatcgtt aatcggacgg ctggcacacg gaatgtagga ggtcgctgag taagtacgaa
2041 caaaatttac gttgtaataa ggtgaggctt gacctacaat tgttcaaata atgcttctgt
2101 agaaatgttt agcattaggc atcttgcgct gctccgcgat gtacgggtca ggtataatgt
2161 gcagtttgac tgaggggacc atgatatgta taggcgaaag gcggggcttc ggttgtacgc
2221 ggttaggagt cccctcagga tatagtagtt tcgcttttgc atagggaggg ggaaatgtag
2281 tcttatgcaa tactcttgta gtcttgcaac atgcttatgt aacgatgagt tagcaacatg
2341 ccttataagg aaagaaaaag caccgtgcat gccgattggt ggaagtaagg tggtatgatc
2401 gtggtatgat cgtggtatga tcgtgcctta ttaggaaggc aacagacggg tctaacacgg
2461 attggacgaa ccactgaatt ccgcattgca gagatattgt atttaagtgc ctagctcgat
2521 acaataaacg ccatttgacc attcaccaca ttggtgtgca cctgggttga tggccggacc
2581 gttgattccc tgacgactac gagcacatgc atgaagcaga aggcttcatt
//
